{"product_id":"capto-hires-ion-exchange-chromatography-columns-29275878","title":"Capto™ HiRes ion exchange chromatography columns","description":"\u003cp\u003eCapto™ HiRes Q and Capto™ HiRes S are prepacked columns for high-resolution purification of proteins and other biomolecules by ion exchange chromatography. They are well-suited for the preparation of highly pure proteins for structural studies and for protein analysis.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eHigh resolution columns—for laboratory scale ion exchange chromatography.\u003c\/li\u003e\n\u003cli\u003eSuitable for preparing highly pure proteins—essential in, for example, structural studies using techniques such as cryo-electron microscopy or protein crystallography.\u003c\/li\u003e\n\u003cli\u003eSuitable for protein analysis in research or quality control—for example, for characterization of target protein charge variants.\u003c\/li\u003e\n\u003cli\u003eHigh quality column—excellent reproducibility, durability, and high chemical and pH stabilities.\u003c\/li\u003e\n\u003cli\u003eReplacement for Mono Q and Mono S columns—delivering similar or improved resolution, with easy transition from one column platform to the other.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eAbout Capto™ HiRes resin\u003c\/p\u003e\n\n\u003cp\u003eThe chromatography resins packed in Capto™ HiRes Q and Capto™ HiRes S ion exchange columns are based on a high-flow agarose base matrix and a small bead size (average bead size 9 μm).  They are strong anion and strong cation exchangers, respectively with ion exchange properties that remain constant during chromatography within the recommended pH range of 2 to 12.\u003c\/p\u003e\n\n\u003cp\u003eA high-performance IEX column format\u003c\/p\u003e\n\n\u003cp\u003eCapto™ HiRes Q and Capto HiRes S IEX resins are prepacked in high-performance Tricorn glass columns of two different sizes. The columns have fittings for simple connection to ÄKTA™ chromatography systems or equivalent high-performance systems. All column parts are biocompatible.\u003c\/p\u003e\n\n\u003cp\u003eHigh-resolution protein purification\u003c\/p\u003e\n\n\u003cp\u003eIn many research areas, for example in structural biology using X-ray crystallography or cryo-electron microscopy (cryo-EM), obtaining homogeneous size and charge of biomolecules is crucial for the elucidation of their structures. High-resolution separation of samples based on their charge properties is essential to secure sample charge homogeneity and success of the study. Capto HiRes columns separate proteins and biomolecules that are very close in net charge, which makes these columns great for these applications.\u003c\/p\u003e\n\n\u003cp\u003eProtein analysis\u003c\/p\u003e\n\n\u003cp\u003eCapto™ HiRes ion exchange columns can be used for protein analysis, in applications such as characterization of target protein charge variants.\u003c\/p\u003e\n\n\u003cp\u003eCapto™ Q HiRes and Capto™ S HiRes replace MonoBeads columns\u003c\/p\u003e\n\n\u003cp\u003eA separation that worked on a Mono Q or Mono S column may be performed on a Capto™ HiRes Q or Capto™ HiRes S column with little modification or optimization. Similar resin selectivity and slightly improved resolution can be expected with the Capto™ HiRes columns while using the same experimental conditions. The similar selectivity of the two columns ensures a smooth transition even for quality control (QC) applications.\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-29998-pdf\"\u003eData file (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-29824-pdf\"\u003eInstructions for use (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Cytiva","offers":[{"title":"1 (29275878)","offer_id":45982056284239,"sku":"29275878","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"1 (29275877)","offer_id":45982056317007,"sku":"29275877","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"1 (29275881)","offer_id":45982056349775,"sku":"29275881","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"1 (29275879)","offer_id":45982056382543,"sku":"29275879","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/digi-29827-original-png_cb88386e-6a0c-424c-a6ca-3a2c6c1663d2.png?v=1785958037","url":"https:\/\/www.danyel.co.il\/products\/capto-hires-ion-exchange-chromatography-columns-29275878","provider":"danyel biotech","version":"1.0","type":"link"}