{"product_id":"capto-adhere-multimodal-chromatography-resin-17544403","title":"Capto™ adhere multimodal chromatography resin","description":"\u003cp\u003eCapto™ adhere is a strong anioin exchange (AIEX) multimodal chromatography resin designed for purification of monoclonal antibodies (mAbs) after the protein A step at process scale.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eIt can be used in flow-through or bind\/elute mode.\u003c\/li\u003e\n\u003cli\u003eWide operational window of pH and conductivity.\u003c\/li\u003e\n\u003cli\u003eResin fulfills industrial demands for security of supply, robust performance, and regulatory support.\u003c\/li\u003e\n\u003cli\u003eSaves time and operating costs when used as part of a two-step chromatographic process with protein A capture.\u003c\/li\u003e\n\u003cli\u003eRemoves contaminants to formulation levels.\u003c\/li\u003e\n\u003cli\u003eHigh capacity and productivity in flow-through mode.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp style=\"margin: 0 0 1rem; font-size: 24px;\"\u003e\u003cbr\u003e\nDifferent selectivity from traditional IEX resins\u003c\/p\u003e\n\n\u003cp\u003eCapto™ adhere resin is composed of a rigid, high-flow agarose matrix and a novel multimodal ligand. The strong multimodal ligand gives a different selectivity from that of conventional ion exchange (IEX) resins.\u003c\/p\u003e\n\n\u003cp style=\"margin: 0 0 1rem; font-size: 24px;\"\u003eSecond step in mAb chromatographic process\u003c\/p\u003e\n\n\u003cp\u003eCapto™ adhere resin can remove key contaminants such as DNA, host cell proteins (HCP), leached protein A, dimers and larger aggregates, and viruses in a single step. Together with a \u003ca href=\"https:\/\/www.cytivalifesciences.com\/shop\/chromatography\/resins\/affinity-antibody\"\u003eprotein A\u003cbr\u003e\ncapture step\u003c\/a\u003e, (using, for example, \u003ca href=\"https:\/\/www.cytivalifesciences.com\/shop\/chromatography\/resins\/affinity-antibody\/mabselect-sure-antibody-purification-resin-p-00700\"\u003eMabSelect™ SuRe resin\u003c\/a\u003e), Capto™ adhere resin allows the design of a two-step chromatographic process for mAbs.\u003c\/p\u003e\n\n\u003cp style=\"margin: 0 0 1rem; font-size: 24px;\"\u003ePart of the Capto™ adhere family\u003c\/p\u003e\n\n\u003cp\u003eFor optimal performance of Capto™ adhere, screening and optimization of loading conditions is recommended, preferably using modern high-throughput process development tools, such as PreDictor™ 96-well filter plates.\u003c\/p\u003e\n\n\u003cp style=\"margin: 0 0 1rem; font-size: 24px;\"\u003ePrepacked columns and other formats\u003c\/p\u003e\n\n\u003cp\u003eCapto™ adhere resin is available in the following formats:\u003c\/p\u003e\n\n\u003cp style=\"margin: 0 0 1rem; font-size: 22px;\"\u003eProcess development scale\u003c\/p\u003e\n\n\u003cul\u003e\n\t\u003cli\u003e\n\u003ca href=\"https:\/\/www.cytivalifesciences.com\/shop\/chromatography\/prepacked-columns\/multimodal\/predictor-capto-adhere-p-00528%C2%A0\"\u003ePreDictor™ Capto™ adhere filter plates\u003c\/a\u003e, 96-well plates for high-throughput screening or process development.\u003c\/li\u003e\n\t\u003cli\u003e\n\u003ca href=\"https:\/\/www.cytivalifesciences.com\/shop\/chromatography\/prepacked-columns\/multimodal\/predictor-robocolumn-capto-adhere-p-00582%C2%A0%C2%A0\"\u003ePreDictor™ Capto™ adhere RoboColumn units\u003c\/a\u003e, miniaturized columns for high-throughput process development.\u003c\/li\u003e\n\t\u003cli\u003e\n\u003ca href=\"https:\/\/www.cytivalifesciences.com\/shop\/chromatography\/prepacked-columns\/multimodal\/hiscreen-capto-adhere-p-00615\"\u003eHiScreen™ Capto™ adhere columns\u003c\/a\u003e, optimized for method and process development.\u003c\/li\u003e\n\t\u003cli\u003e\n\u003ca href=\"\/shop\/chromatography\/prepacked-columns\/hydrophobic-interaction\/f-x-columns-for-mechanistic-modeling-of-chromatography-p-25416\"\u003e\u003cem\u003ef\u003c\/em\u003e(x) column\u003c\/a\u003e, prepacked and precharacterized chromatography column for fast and accurate mechanistic modeling.\u003c\/li\u003e\n\t\u003cli\u003e\n\u003ca href=\"\/shop\/chromatography\/prepacked-columns\/ion-exchange\/prepacked-validation-chromatography-columns-p-10922\"\u003eValidation columns\u003c\/a\u003e, scale-down columns for robust and reproducible process validation and process development (Tricorn™ format)\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp style=\"margin: 0 0 1rem; font-size: 22px;\"\u003eLab scale (for manual or automated systems)\u003c\/p\u003e\n\n\u003cp\u003e\u003ca href=\"https:\/\/www.cytivalifesciences.com\/shop\/chromatography\/prepacked-columns\/multimodal\/hitrap-capto-adhere-p-00468\"\u003eHiTrap™ Capto™ adhere columns\u003c\/a\u003e, for easy use with a syringe, peristaltic pump, or chromatography system.\u003c\/p\u003e\n\n\u003cp style=\"margin: 0 0 1rem; font-size: 22px;\"\u003eProcess-scale\u003c\/p\u003e\n\n\u003cp\u003e\u003ca href=\"https:\/\/www.cytivalifesciences.com\/shop\/chromatography\/prepacked-columns\/multimodal\/capto-adhere-resin-prepacked-in-readytoprocess-single-use-columns-p-00581\"\u003eReadyToProcess™ Capto™ adhere columns\u003c\/a\u003e, 1 L and larger columns for clinical manufacturing that minimize the need for cleaning and cleaning validation.\u003c\/p\u003e\n\n\u003cp style=\"margin: 0 0 1rem; font-size: 22px;\"\u003eProcess characterization kits\u003c\/p\u003e\n\n\u003cp\u003e\u003ca href=\"https:\/\/www.cytivalifesciences.com\/shop\/chromatography\/resins\/ion-exchange\/process-characterization-kit-p-11616\"\u003eProcess characterization kits\u003c\/a\u003e for Capto™ adhere and other resins are designed for studying the potential impact that resin ligand density might have on the process outcome.\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-14882-pdf\"\u003eData file (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-29872-pdf\"\u003eInstructions for use (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Cytiva","offers":[{"title":"1 L","offer_id":45982359093327,"sku":"17544403","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"5 L","offer_id":45982359126095,"sku":"17544404","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"10 L","offer_id":45982359158863,"sku":"17544405","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"25 mL","offer_id":45982359191631,"sku":"17544410","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"100 mL","offer_id":45982359224399,"sku":"17544401","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Standard","offer_id":45982359257167,"sku":"17544460","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/digi-10500-original-png_81bae96d-dbff-4acf-980e-640697dea237.png?v=1785960481","url":"https:\/\/www.danyel.co.il\/products\/capto-adhere-multimodal-chromatography-resin-17544403","provider":"danyel biotech","version":"1.0","type":"link"}