{"product_id":"calmodulin-sepharose-4b-17052901","title":"Calmodulin Sepharose™ 4B","description":"\u003cp\u003eCalmodulin Sepharose 4B affinity resin for purification of proteins with affinity for calmodulin, a highly conserved regulatory protein involved in many cellular processes in eukaryotic cells.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eFor single-step purification of native calmodulin-binding proteins\u003c\/li\u003e\n\u003cli\u003eSuitable for tandem affinity purification (TAP) of protein complexes\u003c\/li\u003e\n\u003cli\u003ePurification of calmodulin-regulated proteins from all eukaryotic cells\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eCalmodulin is a highly conserved regulatory protein found in all eukaryotic cells.This protein is involved in many cellular processes such as glycogen metabolism,cytoskeletal control, neurotransmission, phosphate activity and control of NAD₊\/NADP₊ Calmodulin binds proteins principally through their interactions with hydrophobic sites on its surface. These sites are exposed after a conformational change induced by the action of Ca₂₊ on separate Ca₂₊-binding sites. The binding of enzymes may be enhanced if the enzyme substrate is present and enzyme-substratecalmoldulin-Ca₂₊ complexes are particularly stable\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-12726-pdf\"\u003eInstructions for use (PDF)\u003c\/a\u003e\u003c\/li\u003e\u003c\/ul\u003e","brand":"Cytiva","offers":[{"title":"10 mL","offer_id":45982435508303,"sku":"17052901","price":3206.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/digi-8109-original-png_486c21a3-97eb-4d31-bb4b-db4eeede2093.png?v=1785957315","url":"https:\/\/www.danyel.co.il\/products\/calmodulin-sepharose-4b-17052901","provider":"danyel biotech","version":"1.0","type":"link"}