{"product_id":"biosigma-clearline-low-binding-clearlock-microtubes-cl05-0100dlb","title":"CLEARLine® Low Binding CLEARLock® Microtubes","description":"\u003cp\u003eCLEARLock® CLEARLine® Low Binding Microtubes are designed for laboratories that need reliable recovery of valuable biological samples, especially when working with proteins, DNA, RNA or other nucleic acids at low concentrations.\u003c\/p\u003e \u003cp\u003eSample loss caused by binding to tube surfaces can affect the accuracy and reproducibility of sensitive workflows. Biosigma Low Binding microtubes \u003cb\u003ehelp minimize this risk by reducing interactions between analytes and the tube wall\u003c\/b\u003e, supporting better recovery during handling, centrifugation, preparation and storage.\u003c\/p\u003e \u003cp\u003eThe range includes Protein Low Binding microtubes for biochemistry applications and DNA Low Binding microtubes for molecular biology workflows such as nucleic acid amplification and PCR. \u003cstrong\u003eMade from medical-grade polypropylene\u003c\/strong\u003e, the tubes are \u003cstrong\u003eproduced without intentional addition of PFAS during the production process\u003c\/strong\u003e. They feature a secure CLEARLock® cap, excellent transparency, graduated markings and a writing area for easy identification.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eEach batch is certified free from human DNA, DNase, RNase, ATP, endotoxins and PCR inhibitors\u003c\/b\u003e, making these low binding microcentrifuge tubes suitable for demanding laboratory applications where sample integrity is essential.\u003c\/p\u003e\u003ch2\u003eFeatures\u003c\/h2\u003e\u003cul\u003e \u003cli\u003e\n\u003cstrong\u003eLow binding surface\u003c\/strong\u003e designed to minimize sample loss and improve recovery\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eDedicated DNA and Protein versions\u003c\/strong\u003e for nucleic acid and protein workflows\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eIdeal for low-concentration samples\u003c\/strong\u003e, where even small losses can affect results\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eSecure CLEARLock® hinged cap\u003c\/strong\u003e helps prevent accidental opening during use\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eHermetic closure\u003c\/strong\u003e helps reduce evaporation during long-term storage\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eWritable and pierceable cap\u003c\/strong\u003e for practical sample handling\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eGraduated tube with writing area\u003c\/strong\u003e for easy volume reading and identification\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eExcellent transparency\u003c\/strong\u003e for clear sample visibility\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eHigh centrifugation resistance\u003c\/strong\u003e, up to 30,000 x g\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eWide temperature range\u003c\/strong\u003e, from -80°C to +100°C\u003c\/li\u003e \u003cli\u003e\u003cstrong\u003eAutoclavable at +121°C for 20 minutes\u003c\/strong\u003e\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eMedical-grade polypropylene\u003c\/strong\u003e, non-cytotoxic and non-hemolytic\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eCertified clean batches\u003c\/strong\u003e, free from human DNA, DNase, RNase, ATP, endotoxins and PCR inhibitors\u003c\/li\u003e \u003cli\u003eMetal free\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eRe-closable bag packaging\u003c\/strong\u003e for convenient laboratory storage\u003c\/li\u003e \u003c\/ul\u003e\u003ch2\u003eApplications\u003c\/h2\u003e\u003cul\u003e \u003cli\u003eMolecular biology applications, including nucleic acid amplification and PCR\u003c\/li\u003e \u003cli\u003eBiochemistry applications, including protein sample handling and recovery\u003c\/li\u003e \u003cli\u003eCell culture, chemistry and general laboratory workflows\u003c\/li\u003e \u003cli\u003ePreparation, centrifugation and long-term storage of biological and chemical samples\u003c\/li\u003e \u003cli\u003eHandling of low-volume and low-concentration samples where sample recovery is critical\u003c\/li\u003e \u003cli\u003eFreezer storage of samples at temperatures down to -80°C\u003c\/li\u003e \u003cli\u003eStorage and transport of biological specimens under suitable laboratory conditions\u003c\/li\u003e \u003cli\u003eBiotechnology, pharmaceutical, food industry, research and quality control laboratories\u003c\/li\u003e \u003c\/ul\u003e\u003ch2\u003eProduct Information\u003c\/h2\u003e\u003cp\u003eCLEARLock® CLEARLine® Low Binding Microtubes are available in two dedicated versions: \u003cstrong\u003eProtein Low Binding\u003c\/strong\u003e for protein recovery and \u003cstrong\u003eDNA Low Binding\u003c\/strong\u003e for nucleic acid recovery. \u003cbr\u003eBoth versions are designed to reduce sample loss during handling and storage, especially when working with low-concentration samples.\u003c\/p\u003e \u003cp\u003e \u003cstrong\u003eProtein recovery performance\u003c\/strong\u003e \u003cbr\u003eProtein Low Binding CLEARLock® CLEARLine® Microtubes were tested against low binding and standard microtubes from other suppliers.\u003c\/p\u003e \u003cp\u003eTest procedure: \u003c\/p\u003e\u003cul\u003e \u003cli\u003e Tubes were filled with an aqueous BSA solution and human protein extracts at a concentration of 40 ng\/ml, then stored at 4°C for 24 hours.\u003c\/li\u003e \u003cli\u003e After incubation, proteins were extracted and quantified using the Bradford assay.\u003c\/li\u003e \u003cli\u003e Three independent experiments were performed.\u003c\/li\u003e \u003cli\u003e Results from the independent experiments showed an average recovery greater than 20% compared to standard tubes\u003c\/li\u003e \u003c\/ul\u003e  \u003cp\u003e \u003cstrong\u003eDNA recovery performance\u003c\/strong\u003e \u003cbr\u003eDNA Low Binding CLEARLock® CLEARLine® Microtubes were tested against low binding and standard microtubes from other suppliers.\u003c\/p\u003e \u003cp\u003eTest procedure: \u003c\/p\u003e\u003cul\u003e \u003cli\u003eTubes were filled with 3.5 ng\/µl and 0.35 ng\/µl Human Nuclear DNA and stored at -80°C for 24 hours.\u003c\/li\u003e \u003cli\u003eAfter incubation, 5 and 10 µl of DNA solution were amplified by PCR (35 and 40 cycles). Band intensities were calculated with ImageJ and normalized against Biosigma microtube amplified products.\u003c\/li\u003e \u003cli\u003eThree independent experiments were performed.\u003c\/li\u003e \u003cli\u003e Results from the independent experiments showed an average recovery greater than 20% compared to standard tubes.\u003c\/li\u003e \u003c\/ul\u003e\u003ch2\u003eOrdering Information\u003c\/h2\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eCat. No.\u003c\/th\u003e\n\u003cth\u003eVolume\u003c\/th\u003e\n\u003cth\u003eBinding\u003c\/th\u003e\n\u003cth\u003eDescription\u003c\/th\u003e\n\u003cth\u003eSale unit\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eCL05.0100DLB\u003c\/td\u003e\n\u003ctd\u003e0.5 mL\u003c\/td\u003e\n\u003ctd\u003eDNA Low Binding\u003c\/td\u003e\n\u003ctd\u003eMicrotube with cap Eppendorf type 0.5 ml in PP - CLEARLINE CLEARLock® DNA Low Binding 5 bags of 100 pcs.\u003c\/td\u003e\n\u003ctd\u003e500\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCL05.0100PLB\u003c\/td\u003e\n\u003ctd\u003e0.5 mL\u003c\/td\u003e\n\u003ctd\u003eProtein Low Binding\u003c\/td\u003e\n\u003ctd\u003eMicrotube with cap Eppendorf type 0.5 ml in PP - CLEARLINE CLEARLock® Protein Low Binding 5 bags of 100 pcs.\u003c\/td\u003e\n\u003ctd\u003e500\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCL15.0050DLB\u003c\/td\u003e\n\u003ctd\u003e1.5 mL\u003c\/td\u003e\n\u003ctd\u003eDNA Low Binding\u003c\/td\u003e\n\u003ctd\u003eMicrotube with cap Eppendorf type 1.5 ml in PP - CLEARLINE CLEARLock® DNA Low Binding 4 bags of 50 pcs\u003c\/td\u003e\n\u003ctd\u003e200\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCL15.0050PLB\u003c\/td\u003e\n\u003ctd\u003e1.5 mL\u003c\/td\u003e\n\u003ctd\u003eProtein Low Binding\u003c\/td\u003e\n\u003ctd\u003eMicrotube with cap Eppendorf type 1.5 ml in PP - CLEARLINE CLEARLock® Protein Low Binding 4 bags of 50pcs.\u003c\/td\u003e\n\u003ctd\u003e200\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCL20.0050DLB\u003c\/td\u003e\n\u003ctd\u003e2 mL\u003c\/td\u003e\n\u003ctd\u003eDNA Low Binding\u003c\/td\u003e\n\u003ctd\u003eMicrotube with cap Eppendorf type 2 ml in PP - CLEARLINE CLEARLock® DNA Low Binding 4 bags of 50 pcs.\u003c\/td\u003e\n\u003ctd\u003e200\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCL20.0050PLB\u003c\/td\u003e\n\u003ctd\u003e2 mL\u003c\/td\u003e\n\u003ctd\u003eProtein Low Binding\u003c\/td\u003e\n\u003ctd\u003eMicrotube with cap Eppendorf type 2 ml in PP - CLEARLINE CLEARLock® Protein Low Binding 4 bags of 50pcs\u003c\/td\u003e\n\u003ctd\u003e200\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003ch2\u003eDocuments\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.biosigma.com\/datasheet\/CL05.0100DLB_TDS.pdf\" target=\"_blank\"\u003eTechnical datasheet – CL05.0100DLB, CL15.0050DLB, CL20.0050DLB\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.biosigma.com\/datasheet\/CL05.0100PLB_TDS.pdf\" target=\"_blank\"\u003eTechnical datasheet – CL05.0100PLB, CL15.0050PLB, CL20.0050PLB\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Biosigma","offers":[{"title":"0.5 mL \/ DNA Low Binding","offer_id":67638932406351,"sku":"CL05.0100DLB","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"0.5 mL \/ Protein Low Binding","offer_id":67638932439119,"sku":"CL05.0100PLB","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"1.5 mL \/ DNA Low Binding","offer_id":67638932471887,"sku":"CL15.0050DLB","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"1.5 mL \/ Protein Low Binding","offer_id":67638932504655,"sku":"CL15.0050PLB","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"2 mL \/ DNA Low Binding","offer_id":67638932537423,"sku":"CL20.0050DLB","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"2 mL \/ Protein Low Binding","offer_id":67638932570191,"sku":"CL20.0050PLB","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/5888-1.jpg?v=1791365779","url":"https:\/\/www.danyel.co.il\/products\/biosigma-clearline-low-binding-clearlock-microtubes-cl05-0100dlb","provider":"danyel biotech","version":"1.0","type":"link"}