{"product_id":"beta-n-acetylglucosaminidase-beta-nag-activity-colorimetric-assay-tbs2105-100","title":"Beta-N-Acetylglucosaminidase (Beta-NAG) Activity Colorimetric Assay","description":"\u003cp\u003eβ-Hexosaminidase (β-N-Acetylglucosaminidase, NAGase, EC 3.2.1.52) is a lysosomal enzyme that is expressed in various tissues, including kidneys, liver, lungs, and mast cells. Elevated enzyme levels are associated with many disorders, such as Tay-Sachs and Sandhoff disease, inflammation, and abnormal immune responses.\u003c\/p\u003e\n\u003cp\u003eThe Beta-Hexosaminidase Activity Colorimetric Assay provides a simple and sensitive method for monitoring hexosaminidase activity in biological samples (tissue, cells, serum, urine). This assay uses a synthetic p-nitrophenol derivative (R-pNP) as its substrate and releases pNP which can be measured at absorbance (OD 405 nm). The assay can detect as low as 50 µU of NAGase activity in a variety of samples.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 18px\"\u003e\u003cstrong\u003eApplications\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eThis kit is used for the determination of hexosaminidase activity in biological samples.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 18px\"\u003e\u003cstrong\u003eKey features\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eFast and sensitive:\u003c\/strong\u003e Linear detection range (20 µL sample): 0.05 to 50 U\/L for a 30-minute reaction at 37˚C.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHigh throughput:\u003c\/strong\u003e This can be readily automated on HTS liquid handling systems for processing thousands of samples per day.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003e\u003cspan style=\"font-size: 18px\"\u003e\u003cstrong\u003eStorage Conditions\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eThis kit is shipped on ice. Store all components at -20℃ in a non-frost-free freezer. Shelf life of 12 months after receiving.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 18px\"\u003e\u003cstrong\u003ePreparation\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cimg class=\"alignnone wp-image-10284 lazyloaded\" src=\"https:\/\/tribioscience.com\/wp-content\/uploads\/2020\/04\/TBS2110-2.jpg\" alt=\"\" width=\"681\" height=\"485\" data-lazy-sizes=\"(max-width: 681px) 100vw, 681px\" data-was-processed=\"true\"\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 18px\"\u003e\u003cstrong\u003eStandard Curve\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cimg class=\"alignnone wp-image-10285 lazyloaded\" src=\"https:\/\/tribioscience.com\/wp-content\/uploads\/2020\/04\/TBS2110-3.png\" alt=\"\" width=\"340\" height=\"299\" data-was-processed=\"true\"\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003c!--TBS2105-100 TBS2015-200--\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 13px; font-weight: 700; text-transform: uppercase;\"\u003e\u003cstrong\u003eResearch use only.\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/tribioscience.com\/wp-content\/uploads\/2020\/03\/TBS2105_beta-NAG_V_06_24-update.pdf\"\u003eDatasheet (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/tribioscience.com\/wp-content\/uploads\/2020\/03\/TBS2105-Beta-NAG-Colorimetric-Assay_MSDS_2024.pdf\"\u003eMSDS (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003cp\u003eSun, Y., Wu, Y., He, Z., Wang, Y., Hou, W., Cao, Y., Zhou, Q., \u0026amp; Zhang, R. (2025). Type III CRISPR-mediated flexible RNA excision with engineered guide RNAs. \u003cem\u003eMolecular cell\u003c\/em\u003e, \u003cem\u003e85\u003c\/em\u003e(5), 989–998.e4. \u003ca href=\"https:\/\/doi.org\/10.1016\/j.molcel.2025.01.021\" target=\"_blank\" rel=\"noopener\"\u003ehttps:\/\/doi.org\/10.1016\/j.molcel.2025.01.021\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 13px; font-weight: 700; text-transform: uppercase;\"\u003e\u003cstrong\u003eResearch use only.\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e","brand":"TriBioScience","offers":[{"title":"100 tests","offer_id":45986452013135,"sku":"TBS2105-100","price":1320.0,"currency_code":"ILS","in_stock":true},{"title":"200 tests","offer_id":45986452045903,"sku":"TBS2105-200","price":2231.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/TBS2105-0.jpg?v=1782811265","url":"https:\/\/www.danyel.co.il\/products\/beta-n-acetylglucosaminidase-beta-nag-activity-colorimetric-assay-tbs2105-100","provider":"danyel biotech","version":"1.0","type":"link"}