{"product_id":"archer-variantplex-pan-solid-tumor-panel-ngs-assay-ab0151","title":"Archer VARIANTPlex Pan Solid Tumor Panel","description":"\u003cp\u003e\u003cstrong\u003eIdentify DNA profiles and assess HRD with less reads\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eEfficiently detect single nucleotide variants, copy number variations, insertions, and deletions by targeted NGS of 185 genes along with microsatellite instability, tumor mutational burden, and homologous recombination deficiency status relevant for colorectal, breast, melanoma, gastric, pancreatic, CNS, NSCLC, and other pan-cancer research.\u003c\/p\u003e\u003cp\u003eThe VARIANTPlex Pan Solid Tumor v2 panel is available with integrated HRD assessment. The VARIANTPlex Pan Solid Tumor v1 panel can be paired with the VARIANTPlex HRD Module to provide an HRD assessment on a by-sample basis.\u003c\/p\u003e\u003ch2\u003eKey Benefits\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eFlexible, customizable insights\u003c\/strong\u003e — Combine pre-designed panels, create custom panel content, and easily add targets to your existing assay, while maintaining high performance with minimal workflow disruption.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDetect confidently\u003c\/strong\u003e — Anchored Multiplex PCR (AMP™) chemistry is designed for compatibility with a wide range of sample types, including low-input and potentially degraded samples such as FFPE tissue. Archer Analysis includes a unique outlier detection algorithm that leverages position-specific data to enable variant detection even at low allele frequencies, empowering you to detect confidently.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAchieve efficiency\u003c\/strong\u003e — Streamlined workflows for your lab are enabled by choice of reaction-sized lyophilized reagents or high-throughput liquid reagents, while parallel workflows across all Archer panels provide efficient genomic characterization.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003ePanel Specifications\u003c\/h2\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003e\u003c\/th\u003e\n\u003cth\u003eVARIANTPlex Pan Solid Tumor v1 panel\u003c\/th\u003e\n\u003cth\u003eVARIANTPlex Pan Solid Tumor v2 panel\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eTargeted genes\u003c\/td\u003e\n\u003ctd\u003e185\u003c\/td\u003e\n\u003ctd\u003e185\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eGenomic alterations\u003c\/td\u003e\n\u003ctd\u003eSNVs, Indels, CNVs, ITDs, MSI, TMB\u003c\/td\u003e\n\u003ctd\u003eSNVs, Indels, CNVs, ITDs, MSI, TMB, HRD\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eInput nucleic acid required*\u003c\/td\u003e\n\u003ctd\u003e≥10 ng\u003c\/td\u003e\n\u003ctd\u003e≥10 ng\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eRecommended number of reads\u003c\/td\u003e\n\u003ctd\u003e25 M\u003c\/td\u003e\n\u003ctd\u003e37 M\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eHands-on time\u003c\/td\u003e\n\u003ctd\u003e\u0026lt;3.5 hours\u003c\/td\u003e\n\u003ctd\u003e\u0026lt;3.5 hours\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTotal library prep time\u003c\/td\u003e\n\u003ctd\u003e1.5 days\u003c\/td\u003e\n\u003ctd\u003e1.5 days\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePlatform compatibility\u003c\/td\u003e\n\u003ctd\u003eIllumina®\u003c\/td\u003e\n\u003ctd\u003eIllumina®\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eReagent format\u003c\/td\u003e\n\u003ctd\u003eLyophilized or liquid\u003c\/td\u003e\n\u003ctd\u003eLyophilized or liquid\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eSupported sample types\u003c\/td\u003e\n\u003ctd\u003eFFPE, fresh frozen, cytology smear, FNA\u003c\/td\u003e\n\u003ctd\u003eFFPE, fresh frozen, cytology smear, FNA\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003e\u003csmall\u003e*Input mass requirements vary depending on type and quality. Unless the tumor cellularity and sample quality are high, 50 ng of FFPE-derived nucleic acid should be considered the minimum recommendation. If input is not limiting, 200 ng is recommended.\u003c\/small\u003e\u003c\/p\u003e\u003ch2\u003eGene Targets\u003c\/h2\u003e\u003cp\u003eAKT1, BRAF, EGFR, ERBB2, FOXL2, GNA11, GNAQ, GNAS, HRAS, IDH1, IDH2, KIT, KRAS, MET, NRAS, PDGFRA, PIK3CA, RET, TERT, TP53, ALK, APC, AR, ATRX, CDK4, CDK6, CDKN2A, CTNNB1, DDR2, ERBB3, ERBB4, ESR1, FBXW7, FGFR1, FGFR2, FGFR3, H3F3A, HIST1H3B, JAK2, MAP2K1, MAP2K2, MTOR, MYC, NOTCH1, NOTCH2, NOTCH3, NOTCH4, NTRK1, NTRK2, NTRK3, POLD1, POLE, PTEN, RAF1, RB1, RICTOR, ROS1, SMAD4, SMO, VHL, ATM, BARD1, BRCA1, BRCA2, BRIP1, CDK12, CHEK1, CHEK2, FANCA, FANCL, PALB2, RAD51B, RAD51C, RAD51D, RAD54L, STK11, ABL1, ACVR1, AKT2, AKT3, ARID1A, ARID1B, ARID2, ATR, AURKA, B2M, BAP1, BCOR, BLM, BMPR1A, CCND1, CCND2, CCND3, CCNE1, CDH1, CDKN2B, CHD1, CIC, CSF1R, DAXX, DDX3X, DICER1, EIF1AX, EP300, EPCAM, ERCC1, ERCC2, EZH2, FANCI, FGF19, FGFR4, FH, FLCN, FLT1, FLT3, FLT4, FOXA1, FUBP1, H3F3B, HIST1H3C, HNF1A, JAK1, JAK3, KDM6A, KDR, KEAP1, KLF4, KMT2C, KMT2D, LZTR1, MAP3K1, MDM2, MDM4, MED12, MEN1, MLH1, MPL, MRE11A, MSH2, MSH3, MSH6, MUC16, MUTYH, MYCN, NBN, NF1, NF2, NKX2-1, NPM1, PBRM1, PIK3CB, PIK3R1, PLCB4, PMS2, PPP2R1A, PPP2R2A, PRKD1, PTCH1, PTPN11, RAD50, RAD51, RHOA, RNF43, SDHA, SDHB, SDHC, SDHD, SETD2, SF3B1, SMAD2, SMARCA4, SMARCB1, SRC, SRSF2, STAG2, SUFU, TGFBR2, TP63, TRAF7, TSC1, TSC2, TSHR, U2AF1, XRCC2, XRCC3\u003c\/p\u003e\u003ch2\u003eDocuments\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003eUser guides and protocols\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/sfvideo.blob.core.windows.net\/sitefinity\/docs\/default-source\/protocol\/variantplex-ht-protocol-for-illumina-protocol.pdf?sfvrsn=b8a5f507_26\" target=\"_blank\" rel=\"noopener\"\u003eVARIANTPlex-HT Protocol for Illumina (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/sfvideo.blob.core.windows.net\/sitefinity\/docs\/default-source\/protocol\/variantplex-hs-hgc-protocol-for-illumina-protocol.pdf?sfvrsn=ba2f507_21\" target=\"_blank\" rel=\"noopener\"\u003eVARIANTPlex HS-HGC Protocol for Illumina (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003eProduct inserts\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/sfvideo.blob.core.windows.net\/sitefinity\/docs\/default-source\/supplementary-product-info\/variantplex-ht-pan-solid-tumor-v2-product-insert.pdf?sfvrsn=954dce07_7\" target=\"_blank\" rel=\"noopener\"\u003eVARIANTPlex-HT Pan Solid Tumor v2 Product Insert (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/sfvideo.blob.core.windows.net\/sitefinity\/docs\/default-source\/supplementary-product-info\/variantplex-pan-solid-tumor-v2-product-insert.pdf?sfvrsn=9b4dce07_7\" target=\"_blank\" rel=\"noopener\"\u003eVARIANTPlex Pan Solid Tumor v2 Product Insert (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/sfvideo.blob.core.windows.net\/sitefinity\/docs\/default-source\/supplementary-product-info\/variantplex-ht-pan-solid-tumor-product-insert.pdf?sfvrsn=cd48f207_8\" target=\"_blank\" rel=\"noopener\"\u003eVARIANTPlex-HT Pan Solid Tumor Product Insert (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/sfvideo.blob.core.windows.net\/sitefinity\/docs\/default-source\/supplementary-product-info\/variantplex-pan-solid-tumor-product-insert.pdf?sfvrsn=839ef507_10\" target=\"_blank\" rel=\"noopener\"\u003eVARIANTPlex Pan Solid Tumor Product Insert (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003eFlyers\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/sfvideo.blob.core.windows.net\/sitefinity\/docs\/default-source\/flyer\/flexible-customizable-comprehensive-genomic-profiling-solutions-flyer.pdf?sfvrsn=2dfcf07_5\" target=\"_blank\" rel=\"noopener\"\u003eFlexible Customizable Comprehensive Genomic Profiling Solutions Flyer (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/sfvideo.blob.core.windows.net\/sitefinity\/docs\/default-source\/flyer\/solid-tumor-and-sarcoma-research-panels.pdf?sfvrsn=6f3af107_3\" target=\"_blank\" rel=\"noopener\"\u003eSolid Tumor and Sarcoma Research Panels (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/sfvideo.blob.core.windows.net\/sitefinity\/docs\/default-source\/flyer\/reliable-calling-by-archer-assays-sequenced-with-the-aviti-system-flyer.pdf?sfvrsn=a734f307_6\" target=\"_blank\" rel=\"noopener\"\u003eReliable calling by Archer assays sequenced with the AVITI system flyer (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eOrdering Information\u003c\/h2\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eCat. #\u003c\/th\u003e\n\u003cth\u003eKit\u003c\/th\u003e\n\u003cth\u003eFormat\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eAB0151\u003c\/td\u003e\n\u003ctd\u003eVARIANTPlex-HGC 2.0 Pan Solid Tumor v2 ILMN 8rxn\u003c\/td\u003e\n\u003ctd\u003ev2 \/ HGC 2.0 \/ Illumina \/ 8 rxn\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAB0196\u003c\/td\u003e\n\u003ctd\u003eVARIANTPlex-HT Pan Solid Tumor v2 ILMN 24rxn\u003c\/td\u003e\n\u003ctd\u003ev2 \/ HT \/ Illumina \/ 24 rxn\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAB0142\u003c\/td\u003e\n\u003ctd\u003eVARIANTPlex-HGC 2.0 Pan Solid Tumor ILMN 8rxn\u003c\/td\u003e\n\u003ctd\u003ev1 \/ HGC 2.0 \/ Illumina \/ 8 rxn\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAB0153\u003c\/td\u003e\n\u003ctd\u003eVARIANTPlex-HT Pan Solid Tumor ILMN 24rxn\u003c\/td\u003e\n\u003ctd\u003ev1 \/ HT \/ Illumina \/ 24 rxn\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAB0154\u003c\/td\u003e\n\u003ctd\u003eVARIANTPlex-HT Pan Solid Tumor ILMN 96rxn\u003c\/td\u003e\n\u003ctd\u003ev1 \/ HT \/ Illumina \/ 96 rxn\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003e\u003csmall\u003eHT kits are liquid reagents for high-throughput \/ automated workflows (Illumina only). For research use only. Not for use in diagnostic procedures.\u003c\/small\u003e\u003c\/p\u003e","brand":"Archer","offers":[{"title":"v2 \/ HGC 2.0 \/ Illumina \/ 8 rxn","offer_id":46798466318415,"sku":"AB0151","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"v2 \/ HT \/ Illumina \/ 24 rxn","offer_id":46798466351183,"sku":"AB0196","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"v1 \/ HGC 2.0 \/ Illumina \/ 8 rxn","offer_id":46798466383951,"sku":"AB0142","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"v1 \/ HT \/ Illumina \/ 24 rxn","offer_id":46798466416719,"sku":"AB0153","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"v1 \/ HT \/ Illumina \/ 96 rxn","offer_id":46798466449487,"sku":"AB0154","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/variantplex-ht-dx-liquid-reagents_10029100_850_eff5d664-c21c-4dc0-8f35-c93be50fc282.jpg?v=1789654397","url":"https:\/\/www.danyel.co.il\/products\/archer-variantplex-pan-solid-tumor-panel-ngs-assay-ab0151","provider":"danyel biotech","version":"1.0","type":"link"}