{"product_id":"archer-variantplex-myeloid-v2-panel-ngs-assay-10028437","title":"Archer VARIANTPlex Myeloid v2 Panel","description":"\u003cp\u003e\u003cstrong\u003eDiscover insights into myeloid-origin cancers with a targeted DNA panel\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eDetect single nucleotide variants, insertions, deletions, copy number variations, and internal tandem duplications with targeted NGS of 92 genes relevant for acute myeloid leukemia (AML), myeloproliferative neoplasms (MPN), myelodysplastic syndromes (MDS), Chronic Myeloid Leukemia (CML), Myeloid Sarcomas (MS), and lymphoid malignancies research.\u003c\/p\u003e\u003ch2\u003eKey Benefits\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eDetect confidently\u003c\/strong\u003e — A unique outlier detection algorithm leverages position-specific data to enable variant detection even at low allele frequencies, one of the many ways that Archer Archer Analysis empowers you to detect confidently.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLess QNS\u003c\/strong\u003e — Anchored Multiplex PCR (AMP™) chemistry is designed for compatibility with a wide range of sample types, including low-input and degraded samples such as FFPE tissue.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAchieve efficiency\u003c\/strong\u003e — Streamlined workflows for your lab are enabled by choice of reaction-sized lyophilized reagents or high-throughput liquid reagents, while parallel workflows across all Archer panels provide efficient genomic characterization.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCustomize content\u003c\/strong\u003e — Use Assay Marketplace to modify any panel to fit your lab’s needs or start from scratch to keep up with the pace of discovery.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003ePanel Specifications\u003c\/h2\u003e\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eTargeted genes\u003c\/td\u003e\n\u003ctd\u003e92\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eGenomic alterations\u003c\/td\u003e\n\u003ctd\u003eSNVs, Indels, CNVs, ITDs\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eInput nucleic acid required*\u003c\/td\u003e\n\u003ctd\u003e≥10 ng\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eVariant Allele Frequency\u003c\/td\u003e\n\u003ctd\u003e1-5%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eRecommended number of reads\u003c\/td\u003e\n\u003ctd\u003e1.5 - 10 M\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eHands-on time\u003c\/td\u003e\n\u003ctd\u003e\u0026lt;3.5 hours\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTotal library prep time\u003c\/td\u003e\n\u003ctd\u003e1.5 days\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePlatform compatibility\u003c\/td\u003e\n\u003ctd\u003eIllumina®\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eReagent format\u003c\/td\u003e\n\u003ctd\u003eLyophilized or liquid\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eSupported sample types\u003c\/td\u003e\n\u003ctd\u003eBlood, bone marrow, fresh frozen, BMMC, PBMC\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\u003cp\u003e\u003csmall\u003e*Input mass requirements vary depending on type and quality. Unless the tumor cellularity and sample quality are high, 50 ng of FFPE-derived nucleic acid should be considered the minimum recommendation. If input is not limiting, 200 ng is recommended.\u003c\/small\u003e\u003c\/p\u003e\u003ch2\u003eGene Targets\u003c\/h2\u003e\u003cp\u003eABL1, ANKRD26, ASXL1, ATRX, BCOR, BCORL1, BRAF, BRCC3, BTK, CALR, CBL, CBLB, CBLC, CCND2, CDC25C, CDKN2A, CEBPA, CREBBP, CSF3R, CTCF, CUX1, CXCR4, DCK, DDX41, DHX15, DNMT3A, EED, ETNK1, ETV6, EZH2, FBXW7, FLT3, GATA1, GATA2, GNAS, GNB1, HRAS, IDH1, IDH2, IKZF1, IL7R, JAK1, JAK2, JAK3, KDM6A, KIT, KMT2A, KMT2D, KRAS, LUC7L2, MAP2K1, MPL, MYC, MYD88, NF1, NOTCH1, NPM1, NRAS, NUDT15, PAX5, PDGFRA, PHF6, PPM1D, PRPF8, PTEN, PTPN11, RAD21, RBBP6, RPS14, RUNX1, SAMD9, SAMD9L, SETBP1, SF3B1, SH2B3, SLC29A1, SMC1A, SMC3, SRSF2, STAG2, STAT3, STAT5B, TET2, TP53, TPMT, U2AF1, U2AF2, UBA1, UBTF, WT1, XPO1, ZRSR2\u003c\/p\u003e\u003ch2\u003eDocuments\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003eUser guides and protocols\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/sfvideo.blob.core.windows.net\/sitefinity\/docs\/default-source\/protocol\/variantplex-ht-protocol-for-illumina-protocol.pdf?sfvrsn=b8a5f507_26\" target=\"_blank\" rel=\"noopener\"\u003eVARIANTPlex-HT Protocol for Illumina (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/sfvideo.blob.core.windows.net\/sitefinity\/docs\/default-source\/protocol\/variantplex-hs-hgc-protocol-for-illumina-protocol.pdf?sfvrsn=ba2f507_21\" target=\"_blank\" rel=\"noopener\"\u003eVARIANTPlex HS-HGC Protocol for Illumina (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003eProduct inserts\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/sfvideo.blob.core.windows.net\/sitefinity\/docs\/default-source\/supplementary-product-info\/variantplex-myeloid-v2-product-insert.pdf?sfvrsn=9f0ec807_8\" target=\"_blank\" rel=\"noopener\"\u003eVARIANTPlex Myeloid v2 Product Insert (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/sfvideo.blob.core.windows.net\/sitefinity\/docs\/default-source\/supplementary-product-info\/variantplex-ht-myeloid-v2-panel-product-insert.pdf?sfvrsn=9c0ec807_8\" target=\"_blank\" rel=\"noopener\"\u003eVARIANTPlex-HT Myeloid v2 Panel Product Insert (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003eFlyers\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\u003cli\u003e\u003ca href=\"https:\/\/sfvideo.blob.core.windows.net\/sitefinity\/docs\/default-source\/flyer\/archer-variantplex-myeloid-v2-panel-assay-solutions-flyer.pdf?sfvrsn=cc8ac807_6\" target=\"_blank\" rel=\"noopener\"\u003eArcher VARIANTPlex Myeloid v2 Panel Assay Solutions Flyer (PDF)\u003c\/a\u003e\u003c\/li\u003e\u003c\/ul\u003e\u003ch2\u003eOrdering Information\u003c\/h2\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eCat. #\u003c\/th\u003e\n\u003cth\u003eKit\u003c\/th\u003e\n\u003cth\u003eFormat\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e10028437\u003c\/td\u003e\n\u003ctd\u003eVARIANTPlex-HGC 2.0 Myeloid v2 ILMN 8rxn\u003c\/td\u003e\n\u003ctd\u003eHGC 2.0 \/ Illumina \/ 8 rxn\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e10029353\u003c\/td\u003e\n\u003ctd\u003eVARIANTPlex-LAC Myeloid v2 ILMN 8rxn\u003c\/td\u003e\n\u003ctd\u003eLAC \/ Illumina \/ 8 rxn\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e10029060\u003c\/td\u003e\n\u003ctd\u003eVARIANTPlex-HT Myeloid v2 ILMN 24rxn\u003c\/td\u003e\n\u003ctd\u003eHT \/ Illumina \/ 24 rxn\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e10029271\u003c\/td\u003e\n\u003ctd\u003eVARIANTPlex-HT Myeloid v2 ILMN 96rxn\u003c\/td\u003e\n\u003ctd\u003eHT \/ Illumina \/ 96 rxn\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003e\u003csmall\u003eHT kits are liquid reagents for high-throughput \/ automated workflows (Illumina only). For research use only. Not for use in diagnostic procedures.\u003c\/small\u003e\u003c\/p\u003e","brand":"Archer","offers":[{"title":"HGC 2.0 \/ Illumina \/ 8 rxn","offer_id":46798466121807,"sku":"10028437","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"LAC \/ Illumina \/ 8 rxn","offer_id":46798466154575,"sku":"10029353","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"HT \/ Illumina \/ 24 rxn","offer_id":46798466187343,"sku":"10029060","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"HT \/ Illumina \/ 96 rxn","offer_id":46798466220111,"sku":"10029271","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/variantplex-ht-dx-liquid-reagents_10029100_850_5c736aa8-81c0-49f0-b070-75d1234ffcc1.jpg?v=1789654397","url":"https:\/\/www.danyel.co.il\/products\/archer-variantplex-myeloid-v2-panel-ngs-assay-10028437","provider":"danyel biotech","version":"1.0","type":"link"}