{"product_id":"archer-variantplex-expanded-solid-tumor-panel-ngs-assay-ab0141","title":"Archer VARIANTPlex Expanded Solid Tumor Panel","description":"\u003cp\u003e\u003cstrong\u003eDiscover key DNA signatures of multiple cancers with one panel\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eEfficiently detect single nucleotide variants, insertions, deletions, copy number variations, and microsatellite instability with targeted NGS of 76 relevant genes for colorectal, breast, melanoma, pancreatic, NSCLC and other pan-cancer research.\u003c\/p\u003e\u003ch2\u003eKey Benefits\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eDetect confidently\u003c\/strong\u003e — Archer’s unique outlier detection algorithm leverages position-specific data to enable variant detection even at low allele frequencies, while Archer Analysis makes providing answers easy.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLess QNS\u003c\/strong\u003e — Anchored Multiplex PCR (AMP™) chemistry is designed for compatibility with a wide variety of sample types, including low-input and potentially degraded samples such as FFPE tissue.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAchieve efficiency\u003c\/strong\u003e — Streamlined workflows for your lab are enabled by choice of reaction-sized lyophilized reagents or high-throughput liquid reagents, while parallel workflows across all Archer panels provide efficient genomic characterization.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCustomize content\u003c\/strong\u003e — Use Assay Marketplace to modify any panel to fit your lab's needs or start from scratch to keep up with the pace of discovery.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003ePanel Specifications\u003c\/h2\u003e\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eTargeted genes\u003c\/td\u003e\n\u003ctd\u003e76\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eGenomic alterations\u003c\/td\u003e\n\u003ctd\u003eSNVs, indels, CNVs, ITDs, MSI\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eInput nucleic acid required*\u003c\/td\u003e\n\u003ctd\u003e≥10 ng\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eRecommended number of reads\u003c\/td\u003e\n\u003ctd\u003e6 M\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eHands-on time\u003c\/td\u003e\n\u003ctd\u003e\u0026lt;3.5 hours\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTotal library prep time\u003c\/td\u003e\n\u003ctd\u003e1.5 days\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePlatform compatibility\u003c\/td\u003e\n\u003ctd\u003eIllumina®\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eReagent format\u003c\/td\u003e\n\u003ctd\u003eLyophilized or liquid\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eSupported sample types\u003c\/td\u003e\n\u003ctd\u003eFFPE, fresh frozen, cytology smear, FNA\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\u003cp\u003e\u003csmall\u003e*Input mass requirements vary depending on type and quality. Unless the tumor cellularity and sample quality are high, 50 ng of FFPE-derived nucleic acid should be considered the minimum recommendation. If input is not limiting, 200 ng is recommended.\u003c\/small\u003e\u003c\/p\u003e\u003ch2\u003eGene Targets\u003c\/h2\u003e\u003cp\u003eAKT1, BRAF, EGFR, ERBB2, FOXL2, GNA11, GNAQ, GNAS, HRAS, IDH1, IDH2, KIT, KRAS, MET, NRAS, PDGFRA, PIK3CA, RET, TERT, TP53, ALK, APC, AR, ATRX, CDK4, CDK6, CDKN2A, CTNNB1, DDR2, ERBB3, ERBB4, ESR1, FBXW7, FGFR1, FGFR2, FGFR3, H3F3A, HIST1H3B, JAK2, MAP2K1, MAP2K2, MTOR, MYC, NOTCH1, NOTCH2, NOTCH3, NOTCH4, NTRK1, NTRK2, NTRK3, POLD1, POLE, PTEN, RAF1, RB1, RICTOR, ROS1, SMAD4, SMO, VHL, ATM, BARD1, BRCA1, BRCA2, BRIP1, CDK12, CHEK1, CHEK2, FANCA, FANCL, PALB2, RAD51B, RAD51C, RAD51D, RAD54L, STK11\u003c\/p\u003e\u003ch2\u003eDocuments\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003eUser guides and protocols\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/sfvideo.blob.core.windows.net\/sitefinity\/docs\/default-source\/protocol\/variantplex-ht-protocol-for-illumina-protocol.pdf?sfvrsn=b8a5f507_26\" target=\"_blank\" rel=\"noopener\"\u003eVARIANTPlex-HT Protocol for Illumina (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/sfvideo.blob.core.windows.net\/sitefinity\/docs\/default-source\/protocol\/variantplex-hs-hgc-protocol-for-illumina-protocol.pdf?sfvrsn=ba2f507_21\" target=\"_blank\" rel=\"noopener\"\u003eVARIANTPlex HS-HGC Protocol for Illumina (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003eProduct inserts\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/sfvideo.blob.core.windows.net\/sitefinity\/docs\/default-source\/supplementary-product-info\/variantplex-ht-expanded-solid-tumor-panel-product-insert.pdf?sfvrsn=cf48f207_7\" target=\"_blank\" rel=\"noopener\"\u003eVARIANTPlex-HT Expanded Solid Tumor Panel Product Insert (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/sfvideo.blob.core.windows.net\/sitefinity\/docs\/default-source\/supplementary-product-info\/variantplex-expanded-solid-tumor-product-insert.pdf?sfvrsn=ce9ef507_11\" target=\"_blank\" rel=\"noopener\"\u003eVARIANTPlex Expanded Solid Tumor Product Insert (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eOrdering Information\u003c\/h2\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eCat. #\u003c\/th\u003e\n\u003cth\u003eKit\u003c\/th\u003e\n\u003cth\u003eFormat\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eAB0141\u003c\/td\u003e\n\u003ctd\u003eVARIANTPlex-HGC 2.0 Expanded Solid Tumor ILMN 8rxn\u003c\/td\u003e\n\u003ctd\u003eHGC 2.0 \/ Illumina \/ 8 rxn\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAB0165\u003c\/td\u003e\n\u003ctd\u003eVARIANTPlex-HT Expanded Solid Tumor ILMN 24rxn\u003c\/td\u003e\n\u003ctd\u003eHT \/ Illumina \/ 24 rxn\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAB0170\u003c\/td\u003e\n\u003ctd\u003eVARIANTPlex-HT Expanded Solid Tumor ILMN 96rxn\u003c\/td\u003e\n\u003ctd\u003eHT \/ Illumina \/ 96 rxn\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003e\u003csmall\u003eHT kits are liquid reagents for high-throughput \/ automated workflows (Illumina only). For research use only. Not for use in diagnostic procedures.\u003c\/small\u003e\u003c\/p\u003e","brand":"Archer","offers":[{"title":"HGC 2.0 \/ Illumina \/ 8 rxn","offer_id":46798465859663,"sku":"AB0141","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"HT \/ Illumina \/ 24 rxn","offer_id":46798465892431,"sku":"AB0165","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"HT \/ Illumina \/ 96 rxn","offer_id":46798465925199,"sku":"AB0170","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/variantplex-ht-dx-liquid-reagents_10029100_850_89e0b30e-0dc0-4b4f-807d-8dc40c36fa64.jpg?v=1789654397","url":"https:\/\/www.danyel.co.il\/products\/archer-variantplex-expanded-solid-tumor-panel-ngs-assay-ab0141","provider":"danyel biotech","version":"1.0","type":"link"}