{"product_id":"anti-mouse-pd-1-mouse-monoclonal-antibody-lalapg-tbs10218-0-5","title":"Anti-Mouse PD-1 Mouse Monoclonal Antibody (LALAPG)","description":"\u003cp\u003e\u003cstrong\u003eDescription:\u003c\/strong\u003e Programmed cell death protein 1 (PD-1) is an immune checkpoint receptor expressed on the surface of immune cells, including T cells, B cells, and myeloid cells. It plays a crucial role in immune regulation by delivering inhibitory signals upon interaction with its ligands, PD-L1 and PD-L2, to reduce T cell activity and maintain immune homeostasis. This antibody also contains a LALAPG mutation in the Fc fragment rendering it unable to bind to endogenous Fcγ receptors.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eApplications:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ein vivo blocking of PD-1\/PD-L signaling\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e 150 kDa\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHost:\u003c\/strong\u003e Mouse\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIsotype:\u003c\/strong\u003e Mouse IgG2a Kappa\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMutations:\u003c\/strong\u003e L234A L235A P329G (LALAPG)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eConcentration:\u003c\/strong\u003e 4 mg\/ml\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePurity:\u003c\/strong\u003e \u0026gt;95%\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFormulation:\u003c\/strong\u003e PBS, pH 7.0, no stabilizers or preservatives.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEndotoxin:\u003c\/strong\u003e \u0026lt; 1EU\/mg\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eClonality: \u003c\/strong\u003eMonoclonal\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSterility:\u003c\/strong\u003e 0.2 µm filtered\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eStorage:\u003c\/strong\u003e Stable at 4°C for one month. Store at -20°C for long-term storage.\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 13px; font-weight: 700; text-transform: uppercase;\"\u003e\u003cstrong\u003eResearch use only.\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/tribioscience.com\/wp-content\/uploads\/2025\/03\/TBS10218_Anti-Mouse_PD-1_LALAPG_Mab_Datasheet_2025.pdf\"\u003eDatasheet (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/tribioscience.com\/wp-content\/uploads\/2025\/03\/TBS10218_Anti-Mouse_PD-1_Mab_MSDS-2025-1.pdf\"\u003eMSDS (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"TriBioScience","offers":[{"title":"0.5 MG","offer_id":45986368159823,"sku":"TBS10218-0.5","price":1122.0,"currency_code":"ILS","in_stock":true},{"title":"1 MG","offer_id":45986368192591,"sku":"TBS10218-1","price":1605.0,"currency_code":"ILS","in_stock":true},{"title":"5 MG","offer_id":45986368225359,"sku":"TBS10218-5","price":5963.0,"currency_code":"ILS","in_stock":true},{"title":"25 MG","offer_id":45986368258127,"sku":"TBS10218-25","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/Mouse-Mab.jpg?v=1782809086","url":"https:\/\/www.danyel.co.il\/products\/anti-mouse-pd-1-mouse-monoclonal-antibody-lalapg-tbs10218-0-5","provider":"danyel biotech","version":"1.0","type":"link"}