{"product_id":"altretamine-gpx4-inhibitor-ferroptosis-inducer-tbi5592","title":"Altretamine, GPX4 inhibitor; Ferroptosis inducer","description":"\u003cp\u003e\u003cspan style=\"font-size: 18px\"\u003e\u003cstrong\u003e\u003cu\u003eProduct Details\u003c\/u\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFormal Name:\u003c\/strong\u003e N2,N2,N4,N4,N6,N6-Hexamethyl-1,3,5-triazine-2,4,6-triamine; 2,4,6-Tris(dimethylamino)-1,3,5-triazine\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAlternate Names:\u003c\/strong\u003e Hexamethylmelamine; NSC-13875\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMolecular Formula:\u003c\/strong\u003e C\u003csub\u003e9\u003c\/sub\u003eH\u003csub\u003e18\u003c\/sub\u003eN\u003csub\u003e6\u003c\/sub\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFormula Weight:\u003c\/strong\u003e 210.30\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCAS Number:\u003c\/strong\u003e 645-05-6\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePurity:\u003c\/strong\u003e \u0026gt;98%\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFormulation:\u003c\/strong\u003e powder\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSolubility:\u003c\/strong\u003e Soluble in DMSO (40 mg\/ml)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eStorage:\u003c\/strong\u003e RT\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eStability:\u003c\/strong\u003e ≥ 1 year.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 18px\"\u003e\u003cstrong\u003e\u003cu\u003eApplications\u003c\/u\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eGPX4 inhibitor; Ferroptosis inducer\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 18px\"\u003e\u003cstrong\u003e\u003cu\u003eFunctions\u003c\/u\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eInduces ferroptosis by inhibiting glutathione peroxidase 4 (GPX4) which causes accumulation of lipid hydroperoxides. Ferroptosis induction may be its mechanism of action as a cancer chemotherapeutic. Clinically useful agent for ovarian cancer.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 18px\"\u003e\u003cstrong\u003e\u003cu\u003eApplication Procedures\u003c\/u\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eFirst dissolved in DMSO (40 mg\/ml), then diluted to aqueous buffer.\u003c\/p\u003e\n\u003cp\u003e\u003c!--TBI5592-20MG TBI5592-100MG--\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 13px; font-weight: 700; text-transform: uppercase;\"\u003e\u003cstrong\u003eResearch use only.\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\u003cli\u003e\u003ca href=\"https:\/\/tribioscience.com\/wp-content\/uploads\/2023\/08\/TBI5592_Altretamine.pdf\"\u003eDatasheet (PDF)\u003c\/a\u003e\u003c\/li\u003e\u003c\/ul\u003e","brand":"TriBioScience","offers":[{"title":"20 mg","offer_id":45986597666895,"sku":"TBI5592-20MG","price":288.0,"currency_code":"ILS","in_stock":true},{"title":"100 mg","offer_id":45986597699663,"sku":"TBI5592-100MG","price":821.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/TBI5592.png?v=1782815609","url":"https:\/\/www.danyel.co.il\/products\/altretamine-gpx4-inhibitor-ferroptosis-inducer-tbi5592","provider":"danyel biotech","version":"1.0","type":"link"}