{"title":"Wyatt Technology","description":null,"products":[{"product_id":"wyatt-dawn-8-multi-angle-light-scattering-detector","title":"DAWN 8 Multi-Angle Light Scattering Detector","description":"\u003cspan\u003e\u003cp align=\"center\"\u003e\u003cimg fetchpriority=\"high\" src=\"https:\/\/www.wyatt.com\/wp-content\/uploads\/2019\/10\/DAWN-Hero-Neon-9-19.jpg\" width=\"55%\"\u003e\u003c\/p\u003e\u003c\/span\u003e\n\u003cbr\u003e\n\u003cp\u003eThe world's most advanced light scattering instrument for absolute characterization of proteins, conjugates, macromolecules, and nanoparticles.\u003c\/p\u003e\n\u003cp\u003ePremier MALS\u003c\/p\u003e\n\u003cp\u003eThe DAWN instrument is the premier Multi-Angle static Light Scattering (MALS) detector for absolute characterization of the molar mass and size of macromolecules and nanoparticles in solution. It offers the highest sensitivity, the widest range of molecular weight, size, and concentration, and the largest selection of configurations and optional modules for enhanced capabilities.\u003c\/p\u003e\n\u003chr class=\"no_line\" style=\"margin: 0 auto 10px auto\"\u003e\n\u003cp\u003eSeparation First\u003c\/p\u003e\n\u003cp\u003eMALS is most often used in conjunction with a separation system such as Gel Permeation Chromatography (GPC-MALS), Size Exclusion Chromatography (SEC-MALS), or Field-Flow Fractionation (FFF-MALS) to determine distributions of mass, size, and composition, independent of column calibration by reference standards. \u003c\/p\u003e\n\u003chr class=\"no_line\" style=\"margin: 0 auto 10px auto\"\u003e\n\u003cp\u003eSupported by ASTRA\u003csup\u003e™\u003c\/sup\u003e Software\u003c\/p\u003e\nASTRA Software and its built-in analysis modules support the DAWN MALS instrument, providing the most versatile analysis available for online multi-angle and dynamic light scattering measurements. \n\u003cp\u003eOverview\u003c\/p\u003e\n\u003cp\u003eThe DAWN and its companion \u003ca href=\"https:\/\/www.wyatt.com\/products\/instruments\/optilab-refractive-index-detector.html\"\u003eOptilab\u003csup\u003e™\u003c\/sup\u003e\u003c\/a\u003e dRI detector are the established benchmarks for MALS analysis, cited in thousands of peer-reviewed publications. Multi-angle light scattering detection is indispensable for use with GPC and HPLC-SEC in order to obtain reliable molecular mass distributions and information on molecular conformation, branching ratio, fragments and aggregates.\u003c\/p\u003e\n\u003cp\u003eSEC-MALS with a DAWN and Optilab characterizes conformation and branching of \u003cb\u003esynthetic and natural polymers\u003c\/b\u003e larger than 10 nm in rms radius \u003ci\u003eR\u003c\/i\u003e\u003csub\u003eg\u003c\/sub\u003e. The addition of a \u003ca href=\"https:\/\/www.wyatt.com\/products\/instruments\/viscostar-online-differential-viscometer.html\"\u003eViscoStar\u003csup\u003e™\u003c\/sup\u003e\u003c\/a\u003e differential viscometer creates a GPC triple-detection system that can analyze molecular conformation and size below the \u003ci\u003eR\u003c\/i\u003e\u003csub\u003eg\u003c\/sub\u003e limit of 10 nm and determine Mark-Houwink Sakurada coefficients.\u003c\/p\u003e\n\u003cp\u003eThe combination of a UV\/Vis absorbance detector with a DAWN instrument and Optilab refractive index detector creates a UV-MALS-RI triple-detection system, for analysis of copolymers and protein conjugates (glycoproteins, PEGylated proteins, surfactant-bound membrane proteins, etc.). With the addition of a \u003ca href=\"https:\/\/store.wyatt.com\/shop\/udawn\/udawn3\/wiq\/\"\u003eWyattQELS\u003csup\u003e™\u003c\/sup\u003e DLS module\u003c\/a\u003e for size determination, protein conformation may be analyzed.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ci\u003eM\u003c\/i\u003e\u003csub\u003ew\u003c\/sub\u003e from 200 Da to 1000 MDa\u003c\/li\u003e\n\u003cli\u003eSensitivity: 10 ng\/mL 100 kDa polystyrene in THF, 0.4 µg\/mL BSA (66.4 kDa) in PBS\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ci\u003eR\u003c\/i\u003e\u003csub\u003eg\u003c\/sub\u003e from 10 to 500 nm, up to 1000 nm with shape-specific models\u003c\/li\u003e\n\u003cli\u003eUltra-stable, high-power laser\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThe DAWN may also be used in batch (off-line) mode to characterize the weight-average molar mass, z-average size \n  and second virial coefficient of unfractionated samples.\u003c\/p\u003e\n\u003cp\u003eIn conjunction with a \n  \u003ca href=\"https:\/\/www.wyatt.com\/products\/instruments\/calypso-ii-label-free-biomolecular-interactions.html\"\u003eCalypso\u003csup\u003e™\u003c\/sup\u003e   CG-MALS\u003c\/a\u003e system, the DAWN characterizes macromolecular interactions, label-free and immobilization-free: affinity and absolute stoichiometry of self- and hetero-association of simple or complex molecular systems. The Calypso system also automates the determination of second virial coefficients, cross virial coefficients, average molar masses and sizes.\u003c\/p\u003e\n\u003cp\u003eUltrasonic Cleaning Included\u003c\/p\u003e\n\u003cp\u003eEach DAWN instrument includes an embedded \u003ca href=\"https:\/\/www.wyatt.com\/accessories\/comet.html\"\u003e\u003cb\u003eCOMET\u003csup\u003e™\u003c\/sup\u003e\u003c\/b\u003e\u003c\/a\u003e ultrasonic transducer that cleans the flow cell automatically by agitating the fluid and loosening particles from the glass surfaces. \u003c\/p\u003e\n\u003cp\u003eTemperature-Controlled Models\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eAmbient model\u003c\/li\u003e\n\u003cli\u003eUltra-High-Temperature (UHT) model, from ambient up to +210 °C\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli\u003eStandard Peltier heated\/cooled (H\/C) model, temperature control from -15 °C to +150 °C\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMolar Mass Range\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e200 Da to 1 GDa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMolecular Size Range ( R g )\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e≈ 10 to 500 nm, up to 1000 nm with shape-specific models\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMolecular Size Range ( R h )\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eIn flow mode, 0.5 nm to 300 nm ; batch mode 0.5 nm to 1 μm (requires WyattQELS DLS module or DynaPro NanoStar + fiber optic connection).\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSensitivity\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e10 ng of 100 kDa polystyrene in THF or 200 ng of BSA in PBS, assuming standard 7.8 mm x 300 mm SEC column and no post-column filter\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMobile Phase Compatibility\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eAll-solvent compatible (aqueous and organic). Wetted materials are 316 stainless steel, fused silica or F2 glass, and Kalrez.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMALS Detectors\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eHigh-gain, high dynamic range photodiodes at 18 detection angles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eAuxiliary Detectors\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eLaser monitor for stabilization feedback; forward transmission monitor to correct signals for absorbing samples and to assess data quality.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDynamic Range\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e3,300,000:1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDLS Detector (optional)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eWyattQELS dynamic light scattering module installs directly inside the DAWN chassis. Alternatively, the optical fiber pickup of the DynaPro NanoStar cuvette-based DLS instrument or Mobius DLS-ELS instrument may be installed in the DAWN.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eLaser Wavelength\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e658 nm ± 4 nm; 785 nm optional for use with fluorescing samples\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eLaser Power Control\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eProgrammable 10% to 100%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eFlow Cells\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eFused Silica, optimal for solvent refractive index less than 1.50; F2, optimal for solvent refractive index above 1.50\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eTemperature Options\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eAmbient Heated\/Cooled (HC) -15 °C to +150 °C Ultra-High-Temperature (UHT) ambient to +210 °C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eAnalog Inputs\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e4 differential analog inputs with 24 bit resolution. Input range -10 V to +10 V\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eAnalog Outputs\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e2 analog outputs from user selectable measurements channels -10 V to +10 V\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eOther Inputs\/Outputs\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eAlarm in, Alarm out\/retransmit, Auto-Inject in, Auto inject contact closure retransmit, Recycle In\/Out (operates Orbit recycle valve)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eComputer Interface\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eEthernet\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eFront Panel Display\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e10.1\" (257 mm), capacitive high-resolution screen with multi-touch functionality, displays signals, graphs, instrument settings and diagnostics\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDimensions\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e58 cm (L) x 36 cm (W) x 26 cm (H)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\u003cp\u003e\u003ca href=\"https:\/\/www.wyatt.com\/products\/dawn-brochure-request.html\" target=\"_blank\"\u003eBrochure\u003c\/a\u003e\u003c\/p\u003e","brand":"Wyatt Technology","offers":[{"title":"Ambient \/ Fused Silica, 658 nm \/ None","offer_id":46488395481167,"sku":"WD38-016500","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Ambient \/ Fused Silica, 658 nm \/ WyattQELS","offer_id":46488407834703,"sku":"WD38-016501","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Ambient \/ Fused Silica, 658 nm \/ DLS Fiber","offer_id":46488407867471,"sku":"WD38-0165DLS","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Ambient \/ Fused Silica, 785 nm \/ None","offer_id":46488407900239,"sku":"WD38-017800","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Ambient \/ Fused Silica, 785 nm \/ WyattQELS","offer_id":46488407933007,"sku":"WD38-017801","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Ambient \/ Fused Silica, 785 nm \/ DLS Fiber","offer_id":46488407965775,"sku":"WD38-0178DLS","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Ambient \/ Fused Silica, Aqueous, 658 nm \/ None","offer_id":46488407998543,"sku":"WD38-01AQ6500","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Ambient \/ Fused Silica, Aqueous, 658 nm \/ WyattQELS","offer_id":46488408031311,"sku":"WD38-01AQ6501","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Ambient \/ Fused Silica, Aqueous, 658 nm \/ DLS Fiber","offer_id":46488408064079,"sku":"WD38-01AQ65DLS","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Ambient \/ Fused Silica + Wide-Bore, 658 nm \/ WyattQELS","offer_id":46488408096847,"sku":"WD38-01036501","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Ambient \/ Fused Silica + Wide-Bore, 658 nm \/ DLS Fiber","offer_id":46488408129615,"sku":"WD38-010365DLS","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Ambient \/ Wide-Bore Fused Silica, 658 nm \/ WyattQELS","offer_id":46488408162383,"sku":"WD38-036501","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Ambient \/ Wide-Bore Fused Silica, 658 nm \/ DLS Fiber","offer_id":46488408195151,"sku":"WD38-0365DLS","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Ambient \/ 2 × Wide-Bore Fused Silica, 658 nm \/ WyattQELS","offer_id":46488408227919,"sku":"WD38-03036501","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Ambient \/ 2 × Wide-Bore Fused Silica, 658 nm \/ DLS Fiber","offer_id":46488408260687,"sku":"WD38-030365DLS","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Ambient \/ To be specified \/ To be specified","offer_id":46488408293455,"sku":"WD38","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Heated\/Cooled \/ Fused Silica, 658 nm \/ None","offer_id":46488395513935,"sku":"WD3HC8-016500","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Heated\/Cooled \/ Fused Silica, 658 nm \/ WyattQELS","offer_id":46488408326223,"sku":"WD3HC8-016501","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Heated\/Cooled \/ Fused Silica, 658 nm \/ DLS Fiber","offer_id":46488408358991,"sku":"WD3HC8-0165DLS","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Heated\/Cooled \/ To be specified \/ To be specified","offer_id":46488408391759,"sku":"WD3HC8","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Temperature Regulated \/ Fused Silica, 658 nm \/ None","offer_id":46488395546703,"sku":"WD3TR8-016500","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Temperature Regulated \/ Fused Silica, 658 nm \/ WyattQELS","offer_id":46488408424527,"sku":"WD3TR8-016501","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Temperature Regulated \/ Fused Silica, 658 nm \/ DLS Fiber","offer_id":46488408457295,"sku":"WD3TR8-0165DLS","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Temperature Regulated \/ To be specified \/ To be specified","offer_id":46488408490063,"sku":"WD3TR8","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Ultra-High Temperature \/ To be specified \/ To be specified","offer_id":46488408522831,"sku":"WD3UH8","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/DAWN-Hero-Neon-9-19_ec09b7e7-d1cb-4312-92a5-e60c5d7ceefb.jpg?v=1787675350"},{"product_id":"wyatt-dawn-multi-angle-light-scattering-detector","title":"DAWN Multi-Angle Light Scattering Detector","description":"\u003cspan\u003e\u003cp align=\"center\"\u003e\u003cimg fetchpriority=\"high\" src=\"https:\/\/www.wyatt.com\/wp-content\/uploads\/2019\/10\/DAWN-Hero-Neon-9-19.jpg\" width=\"55%\"\u003e\u003c\/p\u003e\u003c\/span\u003e\n\u003cbr\u003e\n\u003cp\u003eThe world's most advanced light scattering instrument for absolute characterization of proteins, conjugates, macromolecules, and nanoparticles.\u003c\/p\u003e\n\u003cp\u003ePremier MALS\u003c\/p\u003e\n\u003cp\u003eThe DAWN instrument is the premier Multi-Angle static Light Scattering (MALS) detector for absolute characterization of the molar mass and size of macromolecules and nanoparticles in solution. It offers the highest sensitivity, the widest range of molecular weight, size, and concentration, and the largest selection of configurations and optional modules for enhanced capabilities.\u003c\/p\u003e\n\u003chr class=\"no_line\" style=\"margin: 0 auto 10px auto\"\u003e\n\u003cp\u003eSeparation First\u003c\/p\u003e\n\u003cp\u003eMALS is most often used in conjunction with a separation system such as Gel Permeation Chromatography (GPC-MALS), Size Exclusion Chromatography (SEC-MALS), or Field-Flow Fractionation (FFF-MALS) to determine distributions of mass, size, and composition, independent of column calibration by reference standards. \u003c\/p\u003e\n\u003chr class=\"no_line\" style=\"margin: 0 auto 10px auto\"\u003e\n\u003cp\u003eSupported by ASTRA\u003csup\u003e™\u003c\/sup\u003e Software\u003c\/p\u003e\nASTRA Software and its built-in analysis modules support the DAWN MALS instrument, providing the most versatile analysis available for online multi-angle and dynamic light scattering measurements. \n\u003cp\u003eOverview\u003c\/p\u003e\n\u003cp\u003eThe DAWN and its companion \u003ca href=\"https:\/\/www.wyatt.com\/products\/instruments\/optilab-refractive-index-detector.html\"\u003eOptilab\u003csup\u003e™\u003c\/sup\u003e\u003c\/a\u003e dRI detector are the established benchmarks for MALS analysis, cited in thousands of peer-reviewed publications. Multi-angle light scattering detection is indispensable for use with GPC and HPLC-SEC in order to obtain reliable molecular mass distributions and information on molecular conformation, branching ratio, fragments and aggregates.\u003c\/p\u003e\n\u003cp\u003eSEC-MALS with a DAWN and Optilab characterizes conformation and branching of \u003cb\u003esynthetic and natural polymers\u003c\/b\u003e larger than 10 nm in rms radius \u003ci\u003eR\u003c\/i\u003e\u003csub\u003eg\u003c\/sub\u003e. The addition of a \u003ca href=\"https:\/\/www.wyatt.com\/products\/instruments\/viscostar-online-differential-viscometer.html\"\u003eViscoStar\u003csup\u003e™\u003c\/sup\u003e\u003c\/a\u003e differential viscometer creates a GPC triple-detection system that can analyze molecular conformation and size below the \u003ci\u003eR\u003c\/i\u003e\u003csub\u003eg\u003c\/sub\u003e limit of 10 nm and determine Mark-Houwink Sakurada coefficients.\u003c\/p\u003e\n\u003cp\u003eThe combination of a UV\/Vis absorbance detector with a DAWN instrument and Optilab refractive index detector creates a UV-MALS-RI triple-detection system, for analysis of copolymers and protein conjugates (glycoproteins, PEGylated proteins, surfactant-bound membrane proteins, etc.). With the addition of a \u003ca href=\"https:\/\/store.wyatt.com\/shop\/udawn\/udawn3\/wiq\/\"\u003eWyattQELS\u003csup\u003e™\u003c\/sup\u003e DLS module\u003c\/a\u003e for size determination, protein conformation may be analyzed.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ci\u003eM\u003c\/i\u003e\u003csub\u003ew\u003c\/sub\u003e from 200 Da to 1000 MDa\u003c\/li\u003e\n\u003cli\u003eSensitivity: 10 ng\/mL 100 kDa polystyrene in THF, 0.4 µg\/mL BSA (66.4 kDa) in PBS\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ci\u003eR\u003c\/i\u003e\u003csub\u003eg\u003c\/sub\u003e from 10 to 500 nm, up to 1000 nm with shape-specific models\u003c\/li\u003e\n\u003cli\u003eUltra-stable, high-power laser\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThe DAWN may also be used in batch (off-line) mode to characterize the weight-average molar mass, z-average size \n  and second virial coefficient of unfractionated samples.\u003c\/p\u003e\n\u003cp\u003eIn conjunction with a \n  \u003ca href=\"https:\/\/www.wyatt.com\/products\/instruments\/calypso-ii-label-free-biomolecular-interactions.html\"\u003eCalypso\u003csup\u003e™\u003c\/sup\u003e   CG-MALS\u003c\/a\u003e system, the DAWN characterizes macromolecular interactions, label-free and immobilization-free: affinity and absolute stoichiometry of self- and hetero-association of simple or complex molecular systems. The Calypso system also automates the determination of second virial coefficients, cross virial coefficients, average molar masses and sizes.\u003c\/p\u003e\n\u003cp\u003eUltrasonic Cleaning Included\u003c\/p\u003e\n\u003cp\u003eEach DAWN instrument includes an embedded \u003ca href=\"https:\/\/www.wyatt.com\/accessories\/comet.html\"\u003e\u003cb\u003eCOMET\u003csup\u003e™\u003c\/sup\u003e\u003c\/b\u003e\u003c\/a\u003e ultrasonic transducer that cleans the flow cell automatically by agitating the fluid and loosening particles from the glass surfaces. \u003c\/p\u003e\n\u003cp\u003eTemperature-Controlled Models\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eAmbient model\u003c\/li\u003e\n\u003cli\u003eUltra-High-Temperature (UHT) model, from ambient up to +210 °C\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli\u003eStandard Peltier heated\/cooled (H\/C) model, temperature control from -15 °C to +150 °C\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMolar Mass Range\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e200 Da to 1 GDa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMolecular Size Range ( R g )\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e≈ 10 to 500 nm, up to 1000 nm with shape-specific models\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMolecular Size Range ( R h )\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eIn flow mode, 0.5 nm to 300 nm ; batch mode 0.5 nm to 1 μm (requires WyattQELS DLS module or DynaPro NanoStar + fiber optic connection).\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSensitivity\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e10 ng of 100 kDa polystyrene in THF or 200 ng of BSA in PBS, assuming standard 7.8 mm x 300 mm SEC column and no post-column filter\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMobile Phase Compatibility\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eAll-solvent compatible (aqueous and organic). Wetted materials are 316 stainless steel, fused silica or F2 glass, and Kalrez.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMALS Detectors\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eHigh-gain, high dynamic range photodiodes at 18 detection angles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eAuxiliary Detectors\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eLaser monitor for stabilization feedback; forward transmission monitor to correct signals for absorbing samples and to assess data quality.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDynamic Range\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e3,300,000:1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDLS Detector (optional)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eWyattQELS dynamic light scattering module installs directly inside the DAWN chassis. Alternatively, the optical fiber pickup of the DynaPro NanoStar cuvette-based DLS instrument or Mobius DLS-ELS instrument may be installed in the DAWN.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eLaser Wavelength\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e658 nm ± 4 nm; 785 nm optional for use with fluorescing samples\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eLaser Power Control\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eProgrammable 10% to 100%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eFlow Cells\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eFused Silica, optimal for solvent refractive index less than 1.50; F2, optimal for solvent refractive index above 1.50\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eTemperature Options\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eAmbient Heated\/Cooled (HC) -15 °C to +150 °C Ultra-High-Temperature (UHT) ambient to +210 °C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eAnalog Inputs\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e4 differential analog inputs with 24 bit resolution. Input range -10 V to +10 V\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eAnalog Outputs\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e2 analog outputs from user selectable measurements channels -10 V to +10 V\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eOther Inputs\/Outputs\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eAlarm in, Alarm out\/retransmit, Auto-Inject in, Auto inject contact closure retransmit, Recycle In\/Out (operates Orbit recycle valve)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eComputer Interface\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eEthernet\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eFront Panel Display\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e10.1\" (257 mm), capacitive high-resolution screen with multi-touch functionality, displays signals, graphs, instrument settings and diagnostics\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDimensions\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e58 cm (L) x 36 cm (W) x 26 cm (H)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\u003cp\u003e\u003ca href=\"https:\/\/www.wyatt.com\/products\/dawn-brochure-request.html\" target=\"_blank\"\u003eBrochure\u003c\/a\u003e\u003c\/p\u003e","brand":"Wyatt Technology","offers":[{"title":"Ambient \/ Fused Silica, 658 nm \/ None","offer_id":46488396562511,"sku":"WD3-016500","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Ambient \/ Fused Silica, 658 nm \/ WyattQELS","offer_id":46488408555599,"sku":"WD3-016501","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Ambient \/ Fused Silica, 658 nm \/ DLS Fiber","offer_id":46488408588367,"sku":"WD3-0165DLS","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Ambient \/ Fused Silica, 785 nm \/ None","offer_id":46488408621135,"sku":"WD3-017800","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Ambient \/ Fused Silica, 785 nm \/ WyattQELS","offer_id":46488408653903,"sku":"WD3-017801","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Ambient \/ Fused Silica, 785 nm \/ DLS Fiber","offer_id":46488408686671,"sku":"WD3-0178DLS","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Ambient \/ Fused Silica, Aqueous, 658 nm \/ None","offer_id":46488408719439,"sku":"WD3-01AQ6500","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Ambient \/ Fused Silica, Aqueous, 658 nm \/ WyattQELS","offer_id":46488408752207,"sku":"WD3-01AQ6501","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Ambient \/ Fused Silica, Aqueous, 658 nm \/ DLS Fiber","offer_id":46488408784975,"sku":"WD3-01AQ65DLS","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Ambient \/ Fused Silica + Wide-Bore, 658 nm \/ WyattQELS","offer_id":46488408817743,"sku":"WD3-01036501","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Ambient \/ Fused Silica + Wide-Bore, 658 nm \/ DLS Fiber","offer_id":46488408850511,"sku":"WD3-010365DLS","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Ambient \/ Wide-Bore Fused Silica, 658 nm \/ WyattQELS","offer_id":46488408883279,"sku":"WD3-036501","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Ambient \/ Wide-Bore Fused Silica, 658 nm \/ DLS Fiber","offer_id":46488408916047,"sku":"WD3-0365DLS","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Ambient \/ 2 × Wide-Bore Fused Silica, 658 nm \/ WyattQELS","offer_id":46488408948815,"sku":"WD3-03036501","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Ambient \/ 2 × Wide-Bore Fused Silica, 658 nm \/ DLS Fiber","offer_id":46488408981583,"sku":"WD3-030365DLS","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Ambient \/ To be specified \/ To be specified","offer_id":46488409014351,"sku":"WD3","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Heated\/Cooled \/ Fused Silica, 658 nm \/ None","offer_id":46488396595279,"sku":"WD3HC-016500","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Heated\/Cooled \/ Fused Silica, 658 nm \/ WyattQELS","offer_id":46488409047119,"sku":"WD3HC-016501","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Heated\/Cooled \/ Fused Silica, 658 nm \/ DLS Fiber","offer_id":46488409079887,"sku":"WD3HC-0165DLS","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Heated\/Cooled \/ Fused Silica, Aqueous, 658 nm \/ None","offer_id":46488409112655,"sku":"WD3HC-01AQ6500","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Heated\/Cooled \/ Fused Silica, Aqueous, 658 nm \/ WyattQELS","offer_id":46488409145423,"sku":"WD3HC-01AQ6501","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Heated\/Cooled \/ Fused Silica, Aqueous, 658 nm \/ DLS Fiber","offer_id":46488409178191,"sku":"WD3HC-01AQ65DLS","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Heated\/Cooled \/ To be specified \/ To be specified","offer_id":46488409210959,"sku":"WD3HC","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Temperature Regulated \/ Fused Silica, 658 nm \/ None","offer_id":46488396628047,"sku":"WD3TR-016500","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Temperature Regulated \/ Fused Silica, 658 nm \/ WyattQELS","offer_id":46488409243727,"sku":"WD3TR-016501","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Temperature Regulated \/ Fused Silica, 658 nm \/ DLS Fiber","offer_id":46488409276495,"sku":"WD3TR-0165DLS","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Temperature Regulated \/ Fused Silica, Aqueous, 658 nm \/ None","offer_id":46488409309263,"sku":"WD3TR-01AQ6500","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Temperature Regulated \/ Fused Silica, Aqueous, 658 nm \/ WyattQELS","offer_id":46488409342031,"sku":"WD3TR-01AQ6501","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Temperature Regulated \/ Fused Silica, Aqueous, 658 nm \/ DLS Fiber","offer_id":46488409374799,"sku":"WD3TR-01AQ65DLS","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Temperature Regulated \/ To be specified \/ To be specified","offer_id":46488409407567,"sku":"WD3TR","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Ultra-High Temperature \/ Fused Silica, 658 nm \/ None","offer_id":46488396660815,"sku":"WD3UH-016500","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Ultra-High Temperature \/ To be specified \/ To be specified","offer_id":46488409440335,"sku":"WD3UH","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/DAWN-Hero-Neon-9-19_ec09b7e7-d1cb-4312-92a5-e60c5d7ceefb.jpg?v=1787675350"},{"product_id":"wyatt-minidawn-multi-angle-light-scattering-detector","title":"miniDAWN Multi-Angle Light Scattering Detector","description":"\u003cspan\u003e\u003cp align=\"center\"\u003e\u003cimg alt=\"DAWN\" fetchpriority=\"high\" src=\"https:\/\/www.wyatt.com\/wp-content\/uploads\/2019\/10\/miniDAWN-Hero-Neon-9-24-19.jpg\" width=\"65%\"\u003e\u003c\/p\u003e\u003c\/span\u003e\n\u003cp\u003eThe Best in Basic Multi-Angle Light Scattering for Absolute Macromolecular Analysis.\u003c\/p\u003e\n\u003cp\u003eMolar Mass\u003c\/p\u003e\n\u003cp\u003eThe miniDAWN determines absolute molar mass and size to characterize proteins, peptides, small polymers and nanoparticles in solution. Coupled to size exclusion chromatography (SEC or GPC), it eliminates the uncertainty and hassle of column calibration, for true confidence in macromolecular characterization.\u003c\/p\u003e\n\u003chr class=\"no_line\" style=\"margin: 0 auto 10px auto\"\u003e\n\u003cp\u003eSuperb Sensitivity\u003c\/p\u003e\n\u003cp\u003eThe miniDAWN not only offers superb sensitivity—it further enhances productivity thanks to greatly enhanced field serviceability and easy data analysis with One-Click Mw\u003csup\u003e™\u003c\/sup\u003e. \u003c\/p\u003e\n\u003chr class=\"no_line\" style=\"margin: 0 auto 10px auto\"\u003e\n\u003cp\u003eCompatible with ASTRA\u003csup\u003e™\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003eThe miniDAWN is accompanied by \u003ca href=\"https:\/\/www.wyatt.com\/products\/software\/astra.html\"\u003eASTRA\u003c\/a\u003e, the most versatile software package available for analysis of online multi-angle and dynamic light scattering. ASTRA and the miniDAWN incorporate advanced ease-of-use features that help guarantee excellent measurements with a single click.\u003c\/p\u003e\n\u003cp\u003eMolar mass, absolutely\u003c\/p\u003e\n\u003cdiv class=\"column one-second\"\u003e\n\u003cp\u003eWyatt's miniDAWN is most often used in conjunction with size exclusion chromatography \n  \t\t(\u003ca href=\"https:\/\/www.wyatt.com\/solutions\/techniques\/sec-mals-molar-mass-size-multi-angle-light-scattering.html\"\u003eSEC-MALS\u003c\/a\u003e) or field-flow fractionation \n  \t\t(\u003ca href=\"https:\/\/www.wyatt.com\/solutions\/techniques\/fff-mals-characterization-of-nanoparticles-colloids-macromolecules.html\"\u003eFFF-MALS\u003c\/a\u003e) \n  \t\tto determine distributions of molecular weight, size and composition. No need to make assumptions about molecular \n          conformation or ideal column interactions.\u003c\/p\u003e\n\u003cp\u003eCharacterize:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eProteins, small peptides and oligonucleotides\u003c\/li\u003e\n\u003cli\u003eSynthetic and natural polymers\u003c\/li\u003e\n\u003cli\u003eNanoparticles, virus-like  particles and vesicles\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eMeasurement Range:\u003c\/p\u003e\n\u003cul style=\"margin-right: 15 px;\"\u003e\n\u003cli\u003eMW from  200 Da to 10 MDa\u003c\/li\u003e\n\u003cli\u003e\n\u003ci\u003er\u003csub\u003eg\u003c\/sub\u003e\u003c\/i\u003e from  10 to 50 nm, up to 150 nm with shape-specific models\u003c\/li\u003e\n\u003cli\u003esensitivity down to 25 ng of 100 kDa polystyrene in THF, injected on a standard GPC column\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"column one-second\"\u003e\n\u003cimg alt=\"protein molar mass characterization \n        with miniDAWN\" src=\"https:\/\/www.wyatt.com\/wp-content\/uploads\/2019\/05\/4-protein_Mwchromatogram_50pc.jpg\" style=\"float: none; width:90%; margin-left: 15px;\" title=\"protein molar mass characterization with miniDAWN\"\u003e\n\u003cp style=\"color: #075c97;\"\u003eThe miniDAWN determines molecular weight independently of column calibration. Here MALS \n      shows that the earliest-eluting molecule does not have the highest molar mass.  \n    \t\u003c\/p\u003e\n\u003c\/div\u003e\n\n\u003cp\u003e\n          The miniDAWN's performance is exceeded only by the \n          \u003ca href=\"https:\/\/www.wyatt.com\/products\/instruments\/dawn-multi-angle-light-scattering-detector.html\"\u003eDAWN\u003csup\u003e™\u003c\/sup\u003e\u003c\/a\u003e which covers a wider range \n          of size and molecular weight, with even better sensitivity and additional optional modules.\n      \u003c\/p\u003e\n\u003cp\u003eUltrasonic Cleaning Included\u003c\/p\u003e\n\u003cp\u003eEach miniDAWN includes an embedded \u003ca href=\"https:\/\/store.wyatt.com\/shop\/minidawn-treos\/treos-ii\/wyatt-comet\/\"\u003e\u003cb\u003eCOMET\u003csup\u003e™\u003c\/sup\u003e\u003c\/b\u003e\u003c\/a\u003e ultrasonic transducer that cleans the flow cell automatically by agitating the fluid and loosening particles from the glass surfaces.\u003c\/p\u003e\n\u003cp\u003eModularity = Productivity\u003c\/p\u003e\n\u003cp\u003eThe miniDAWN incorporates a fully modular design. Each module can be tested independently by the software to verify that it is functioning correctly. This imparts nearly complete field serviceability, since malfunctioning modules can be replaced and validated on-site by service engineers with no further calibration or alignment.\u003c\/p\u003e\n\u003cp\u003eThe miniDAWN is also field-upgradeable: the embedded \u003ca href=\"https:\/\/store.wyatt.com\/shop\/udawn\/udawn3\/wiq\/\"\u003eWyattQELS\u003csup\u003e™\u003c\/sup\u003e DLS Module\u003c\/a\u003e for measuring hydrodynamic radii from 0.5 to 50 nm can be installed on-site as well as in new units shipped from the factory.\u003c\/p\u003e\n\u003cp\u003eNot just SEC-MALS...\u003c\/p\u003e\n\u003cp\u003eWyatt's miniDAWN may be used in batch (off-line) mode or in conjunction with a \n          \u003ca href=\"https:\/\/www.wyatt.com\/products\/instruments\/calypso-ii-label-free-biomolecular-interactions.html\"\u003eCalypso\u003csup\u003e™\u003c\/sup\u003e\u003c\/a\u003e CG-MALS system for \n          characterization of average solution properties as well as macromolecular interaction properties including protein-protein \n          binding affinity and complex stoichiometry.\u003c\/p\u003e\n\u003cdiv class=\"column one-second\"\u003e\n\u003cp\u003eSimplicity personified\u003c\/p\u003e\n\u003cp\u003eWith miniDAWN and ASTRA\u003csup\u003e™\u003c\/sup\u003e, SEC-MALS became a whole lot easier. Sample-specific methods are set up in three short steps with \n          ASTRA's Method Wizard, and new capabilities for automatic data processing mean that it takes just one click from your sample to a \n          full report of the molecular weight and size results. \u003c\/p\u003e\n\u003cp\u003eThe miniDAWN's System Ready monitor will even let you know when the system is fully equilibrated with low baseline noise,\n          ready to run.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"column one-second\"\u003e\n\u003cimg alt=\"Astra\" src=\"https:\/\/www.wyatt.com\/wp-content\/uploads\/2019\/05\/astra-steps.jpg\" style=\"float:none; width:90%;\" title=\"Astra\"\u003e\n\u003c\/div\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMolar Mass Range\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e200 Da to 10 MDa (proteins) or 1 MDa (linear polymers)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMolecular Size Range ( R g )\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e≈ 10 nm to 50 nm, up to 150 nm with shape-specific models\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMolecular Size Range ( R h )\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eIn flow mode, 0.5 nm to 50 nm ; batch mode 0.5 nm to 1 μm (requires WyattQELS DLS module or DynaPro NanoStar + fiber optic connection)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSensitivity\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e25 ng of 100 kDa polystyrene in THF or 500 ng of BSA in PBS, assuming standard 7.8 mm x 300 mm SEC column and no post-column filter\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMobile Phase Compatibility\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eAll-solvent compatible (aqueous and organic); Wetted materials are 316 stainless steel, fused silica, and Kalrez\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMALS Detectors\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eHigh-gain, high dynamic range photodiodes at 3 detection angles\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eAuxiliary Detectors\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eLaser monitor for stabilization feedback; forward transmission monitor to correct signals for absorbing samples and to assess data quality\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDynamic Range\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e3,300,000:1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDLS Detector (optional)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eWyattQELS dynamic light scattering module installs directly inside the miniDAWN chassis. Alternatively, the optical fiber pickup of the DynaPro NanoStar cuvette-based DLS instrument or Mobius DLS-ELS instrument may be installed in the miniDAWN.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eLaser Wavelength\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e658 nm ± 4 nm\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eLaser Power Control\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eProgrammable 10% to 100%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSample Temperature Control\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eAmbient\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eAnalog Inputs\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e2 differential analog inputs with 24 bit resolution; Input range -10 V to +10 V\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eAnalog Outputs\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e1 analog output from user selectable measurements channels -10 V to +10 V\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eOther Inputs\/Outputs\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eAlarm in, Alarm out\/retransmit, Auto-inject in, Auto inject contact closure retransmit, Recycle In\/Out (operates Orbit recycle valve)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eComputer Interface\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eEthernet\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eProcessed Data Rate\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eUp to 36.6 Hz\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eFront Panel Display\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e7\" (178 mm), high-resolution, multi-touch display for viewing\/setting signals, instrument settings and diagnostics\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDimensions\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e58 cm (L) x 36 cm (W) x 18 cm (H)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\u003cp\u003e\u003ca href=\"https:\/\/www.wyatt.com\/products\/minidawn-brochure-request.html\" target=\"_blank\"\u003eBrochure\u003c\/a\u003e\u003c\/p\u003e","brand":"Wyatt Technology","offers":[{"title":"Standard \/ No QELS","offer_id":46488396922959,"sku":"WMD3-00","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Standard \/ With QELS","offer_id":46488409473103,"sku":"WMD3-01","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Standard \/ With DLS","offer_id":46488409505871,"sku":"WMD3-DLS","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Aqueous \/ No QELS","offer_id":46488409538639,"sku":"WMD3-AQ00","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Aqueous \/ With QELS","offer_id":46488409571407,"sku":"WMD3-AQ01","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Aqueous \/ With DLS","offer_id":46488409604175,"sku":"WMD3-AQDLS","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"To be specified \/ To be specified","offer_id":46488409636943,"sku":"WMD3","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/miniDAWN-Hero-Neon-9-24-19.jpg?v=1787675355"},{"product_id":"wyatt-microdawn-mals-detector-for-uhplc","title":"microDAWN MALS Detector for UHPLC","description":"\u003cspan\u003e\u003cp align=\"center\"\u003e\u003cimg alt=\"microDAWN\" src=\"https:\/\/www.wyatt.com\/wp-content\/uploads\/2019\/10\/microDAWN-Hero-Neon-9-24-19.jpg\" width=\"65%\"\u003e\u003c\/p\u003e\u003c\/span\u003e\n\u003cp\u003eThe Only Multi-Angle Light Scattering Detector for UHPLC\u003c\/p\u003e\n\u003cp\u003eUHPLC-SEC System\u003c\/p\u003e\u003cp\u003eThe microDAWN can be coupled to \u003ci\u003eany\u003c\/i\u003e UHPLC-SEC system to determine absolute molecular weights and sizes of polymers, peptides, or proteins directly, without resorting to column calibration or reference standards. The microDAWN produces minimal band broadening in order to maintain the narrow peaks typical of UHPLC, while meeting or exceeding the sensitivity of the miniDAWN\u003csup\u003e™\u003c\/sup\u003e.\u003c\/p\u003e\n\u003chr class=\"no_line\" style=\"margin: 0 auto 10px auto\"\u003e\n\u003cp\u003ePolymer Characterization\u003c\/p\u003e\n\u003cp style=\"display: flex; align-items: flex-start; gap: 10px;\"\u003e\n\u003ci class=\"fa fa-file-pdf-o fa-lg\" style=\"flex-shrink: 0; margin-top: 4px;\"\u003e\u003c\/i\u003e\n\u003cspan\u003e\n    \n      Read our paper published in Nature Scientific Reports:\n    \u003cbr\u003e\n\u003ca href=\"https:\/\/www.nature.com\/articles\/s41598-017-09051-1\" style=\"\" target=\"_blank\"\u003e“Measuring proteins with greater speed and resolution while reducing sample size”\u003c\/a\u003e\n\u003c\/span\u003e\n\u003c\/p\u003e\n\u003chr class=\"no_line\" style=\"margin: 0 auto 10px auto\"\u003e\n\u003cp\u003eUse of SEC-MALS\u003c\/p\u003e\n\u003cp style=\"display: flex; align-items: flex-start; gap: 10px;\"\u003e\n\u003ci class=\"fa fa-file-pdf-o fa-lg\" style=\"flex-shrink: 0; margin-top: 4px;\"\u003e\u003c\/i\u003e\n\u003cspan\u003e\n    \n      Download our white paper on the microDAWN:\n    \u003cbr\u003e\n\u003ca href=\"https:\/\/wyattfiles.s3-us-west-2.amazonaws.com\/literature\/white-papers\/WP1004-Absolute-characterization-of-polymers-with-light-scattering-and-UHP-SEC.pdf\" style=\"\" target=\"_blank\"\u003e“Absolute characterization of polymers with light scattering and UHP-SEC”\u003c\/a\u003e\n\u003c\/span\u003e\n\u003c\/p\u003e\n\u003cdiv class=\"column one-second\"\u003e\n\u003cp\u003eThe microDAWN MALS detector performs absolute characterization of macromolecules eluting from UHPLC, determining molar mass and size \u003ci\u003eindependently\u003c\/i\u003e of retention time and molecular reference standards. This instrument offers superb sensitivity over a wide range of molar mass, size and concentrations. In most respects the microDAWN is similar to the well-established \n      \t\u003ca href=\"https:\/\/www.wyatt.com\/products\/instruments\/minidawn-multi-angle-light-scattering-detector-sec-mals.html\"\u003eminiDAWN™\u003c\/a\u003e, a workhorse MALS instrument used in hundreds of labs around the world for characterizing proteins \n     \t and other molecules smaller than 50 nm in radius.\u003c\/p\u003e\n\u003cp\u003eDistinctly from the miniDAWN, the microDAWN is uniquely suitable for use in conjunction with UHPLC Size Exclusion \n      \tChromatography (\u003ca href=\"https:\/\/www.wyatt.com\/solutions\/techniques\/sec-mals-molar-mass-size-multi-angle-light-scattering.html\"\u003eSEC-MALS\u003c\/a\u003e) thanks to its small interdetector dispersion. In some cases it may be used with ion-exchange or other types of chromatography. Regardless of the specifics, the microDAWN produces minimal band broadening in order to maintain the narrow peaks typical of UHPLC.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"column one-second\" style=\"text-align:center;\"\u003e\n\u003cdiv style=\"padding: 15px;\"\u003e\n\u003cimg align=\"right\" alt=\"microDAWN UHPLC Experimental Setup\" height:=\"399px\" src=\"https:\/\/www.wyatt.com\/wp-content\/uploads\/2019\/05\/UHPLC-microDAWN-microOptilab-Neon-System.jpg\" width=\"350px\"\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003cp\u003e\n\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003ci\u003eM\u003c\/i\u003e\u003csub\u003ew\u003c\/sub\u003e from 200 Da to 10 MDa\u003c\/li\u003e\n\u003cli\u003eSensitivity: 1.0 µg\/mL BSA (66.4 kDa) in PBS; 50 ng\/mL 100 kDa polystyrene in THF.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ci\u003eR\u003c\/i\u003e\u003csub\u003eg\u003c\/sub\u003e from 10 to 50 nm\u003c\/li\u003e\n\u003cli\u003eUltra-stable laser\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThe microDAWN and its companion \n          \u003ca href=\"https:\/\/www.wyatt.com\/products\/instruments\/microOptilab-uhplc-refractometer-sec-mals.html\"\u003emicroOptilab\u003csup\u003e™\u003c\/sup\u003eRefractive Index Detector\u003c\/a\u003e interface to most standard UHPLC systems. As these detectors are based on the advanced technology of Wyatt's miniDAWN and \u003ca href=\"https:\/\/www.wyatt.com\/products\/instruments\/optilab-refractive-index-detector.html\"\u003eOptilab\u003csup\u003e™\u003c\/sup\u003e\u003c\/a\u003e, respectively, users may be confident in the underlying capabilities cited in \u003ca href=\"https:\/\/www.wyatt.com\/library\/bibliography.html\"\u003ethousands of \n            peer-reviewed publications\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003eUltrasonic Cleaning Included\u003c\/p\u003e\n\u003cp\u003eEach microDAWN includes a \u003ca href=\"https:\/\/store.wyatt.com\/shop\/minidawn-treos\/treos-ii\/wyatt-comet\/\"\u003e\u003cb\u003eCOMET\u003csup\u003e™\u003c\/sup\u003e\u003c\/b\u003e\u003c\/a\u003e ultrasonic transducer that cleans MALS flow cells automatically by agitating the fluid and loosening particles from the glass surfaces.\u003c\/p\u003e\n\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMolar Mass Range\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e200 Da to 10 MDa (proteins) or 1 MDa (linear polymers)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMolecular or Particle Size Range (Radius, R g )\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e10 nm to 50 nm, up to 150 nm with shape-specific models\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMolecular Size Range ( R h )\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eIn flow mode, 0.5 nm to 30 nm; batch mode 0.5 nm to 1 μm (requires WyattQELS DLS module or DynaPro NanoStar + fiber optic connection)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSensitivity\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e3.5 ng of 100 kDa polystyrene in THF or 70 ng of BSA in PBS, assuming a 15 cm UHPLC-SEC column and no post-column filter\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMALS Detectors\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eHigh-gain, high dynamic range photodiodes at 3 detection angles\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDynamic Range\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e3,300,000:1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eAuxiliary Detectors\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eLaser monitor for stabilization feedback; forward transmission monitor to correct signals for absorbing samples and to assess data quality\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDLS Detector (optional)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eWyattQELS dynamic light scattering module installs directly inside the microDAWN chassis. Alternatively, the optical fiber pickup of the DynaPro NanoStar cuvette-based DLS instrument or ZetaStar DLS-ELS instrument may be installed in the DAWN .\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eLaser Wavelength\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e658 nm ± 4 nm\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eLaser Power Control\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eProgrammable 10% to 100%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSample Temperature Control\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eAmbient\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eInterdetector Band Broadening\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e(Increase in FWHM @ 0.3 mL\/min) Upstream detector to microDAWN: \u0026lt; 1.5 μL;\nUpstream detector to downstream detector: \u0026lt; 1.6 μL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eWetted Materials\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e316 stainless steel, fused silica, PEEK, PTFE, MP35N iron-free alloy\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eAnalog Inputs\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e2 differential analog inputs with 24 bit resolution; Input range -10 V to +10 V\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eAnalog Outputs\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e1 analog output from user selectable measurements channels -10 V to +10 V\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eOther Inputs\/Outputs\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eAlarm in, Alarm out\/retransmit, Auto-inject in, Auto inject contact\nclosure retransmit, Recycle In\/Out (operates Orbit recycle valve)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eComputer Interface\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eEthernet\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eFront Panel Display\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e7\" (178 mm), high-resolution, multi-touch display for viewing\/setting signals, instrument settings and diagnostics\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eProcessed Data Transmission Rate\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eUp to 73 Hz\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDimensions\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e58 cm (L) x 36 cm (W) x 18 cm (H)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\u003cp\u003e\u003ca href=\"https:\/\/www.wyatt.com\/products\/microdawn-brochure-request.html\" target=\"_blank\"\u003eBrochure\u003c\/a\u003e\u003c\/p\u003e","brand":"Wyatt Technology","offers":[{"title":"Standard \/ No QELS","offer_id":46488397185103,"sku":"WUD3-00","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Standard \/ With QELS","offer_id":46488409768015,"sku":"WUD3-01","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Standard \/ With DLS","offer_id":46488409800783,"sku":"WUD3-DLS","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Aqueous \/ No QELS","offer_id":46488409833551,"sku":"WUD3-AQ00","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Aqueous \/ With QELS","offer_id":46488409866319,"sku":"WUD3-AQ01","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Aqueous \/ With DLS","offer_id":46488409899087,"sku":"WUD3-AQDLS","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"To be specified \/ To be specified","offer_id":46488409931855,"sku":"WUD3","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/microDAWN-Hero-Neon-9-24-19_0af21c4e-49d5-427d-84b4-03e944a0c11a.jpg?v=1787675358"},{"product_id":"wyatt-ultradawn-real-time-mals-detector","title":"ultraDAWN Real-Time MALS Detector","description":"\u003cspan\u003e\u003cp align=\"center\"\u003e\u003cimg src=\"https:\/\/www.wyatt.com\/wp-content\/uploads\/2026\/07\/wyatt-ultradawn-ultradawn-pilot.webp\" width=\"85%\"\u003e\u003c\/p\u003e\u003c\/span\u003e\n\u003cp\u003eA breakthrough in process analytical technology for production of nanoparticles, biopharmaceuticals and polymers.\u003c\/p\u003e\n\u003cp\u003eReal-Time Multi-Angle Light Scattering\u003c\/p\u003e\n\u003cp\u003eultraDAWN measures multi-angle and dynamic light scattering and reports the results – molecular weight, size, polydispersity, particle concentration and more – in real time. With \u003ca href=\"https:\/\/www.wyatt.com\/solutions\/techniques\/real-time-mals.html\"\u003eRT-MALS\u003c\/a\u003e, critical quality attributes (CQAs) can be monitored directly, for rapid feedback on product and process quality. \u003c\/p\u003e\n\u003chr class=\"no_line\" style=\"margin: 0 auto 10px auto\"\u003e\n\u003cp\u003eBenefits of RT-MALS\u003c\/p\u003e\n\u003cp\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eAccelerate process development and scale-up\u003c\/li\u003e\n\u003cli\u003eIncrease yield, reduce overall time until lot release\u003c\/li\u003e\n\u003cli\u003eMaintain product quality with confidence\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eWhere MALS and PAT meet\u003c\/p\u003e\n\u003cp\u003eThe ultraDAWN and ultraDAWN Pilot are unique members of the DAWN\u003csup\u003e™\u003c\/sup\u003e family of MALS instruments. Instead of residing in the analytical lab, they are adapted to inline\/online integration with bioprocess development  and production environments. Together with OBSERVER\u003csup\u003e™\u003c\/sup\u003e real-time software, ultraDAWN calculates and reports molar mass, size, particle concentration and other attributes, up to 300 times per minute, during a unit operation such as chromatographic purification or lipid nanoparticle production.\u003c\/p\u003e\n\u003cp\u003ePAT instrumentation typically monitors process parameters such as pH, temperature, pressure, UV and feedstock, which are tied only indirectly to product properties and quality. ultraDAWN revolutionizes process development with its continuous, direct measurements of relevant product attributes.\u003c\/p\u003e\n\u003cdiv class=\"column one-second\"\u003e\n\u003cp\u003eBuilt in the NEON\u003csup\u003e™\u003c\/sup\u003e platform, ultraDAWN provides an intelligent user interface indicating real-time and time sequences of molar mass, size and\/or particle concentration as well as system health diagnostics and event history. With photodetectors at eighteen scattering angles plus one more to measure light transmitted through the flow cell, the ultraDAWN provides a solution for monitoring multiple biophysical product attributes:\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eMacromolecules: \u003c\/b\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ci\u003eM\u003c\/i\u003e\u003csub\u003ew\u003c\/sub\u003e from 10\u003csup\u003e3\u003c\/sup\u003e to 10\u003csup\u003e9\u003c\/sup\u003e g\/mol\u003c\/li\u003e\n\u003cli\u003e\n\u003ci\u003eR\u003c\/i\u003e\u003csub\u003eg\u003c\/sub\u003e from 10 to 250 nm\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eNanoparticles:\u003c\/b\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eradius from 10 to 250 nm\u003c\/li\u003e\n\u003cli\u003eparticle concentration (concentration range depends on particle size)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eAAV and other small viral vectors:\u003c\/b\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003efull:total capsid ratio Vg\/Cp\u003c\/li\u003e\n\u003cli\u003etotal, full and empty capsid titer (AAV\/mL)\u003c\/li\u003e\n\u003cli\u003etotal AAV, capsid and genome molecular weight\u003c\/li\u003e\n\u003cli\u003erms radius \u003ci\u003eR\u003c\/i\u003e\u003csub\u003eg\u003c\/sub\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eWith the addition of an optional WyattQELS embedded DLS module, ultraDAWN also  monitors hydrodynamic radius from 0.5 to 1000 nm (flow-rate dependent) and the polydispersity index.\u003c\/p\u003e\n\u003cp\u003eultraDAWN offers versatile options for PAT, including:\u003c\/p\u003e\n\u003cul\u003e\n\u003cp\u003eIn-line or on-line configuration\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cb\u003eultraDAWN:\u003c\/b\u003eIn-line flow up to 150 mL\/min, and up to 2 L\/min with a flow splitter\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eultraDAWN Pilot:\u003c\/b\u003e In-line flow up to 1000 mL\/min, and up to 15 L\/min with a flow splitter\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eProcess sampling or slipstream sampling with recirculation\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cb\u003eultraDAWN:\u003c\/b\u003e 0.5 to 50 mL\/min\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eultraDAWN Pilot:\u003c\/b\u003e 50–500 mL\/min\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cli\u003eAnalog integration with bench-scale preparative chromatography and other processing equipment\u003c\/li\u003e\n\u003cli\u003eDigital integration with production control software via OPC-UA\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"column one-second\"\u003e\n\u003cp align=\"center\"\u003e\u003cimg align=\"center\" alt=\"ultraDAWN\" src=\"https:\/\/www.wyatt.com\/wp-content\/uploads\/2019\/11\/ultraDAWN-UI.jpg\" title=\"ultraDAWN\" width=\"350px\"\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMolar Mass Range\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e1 kDa to 1 GDa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSize Range ( R g )\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e10 nm to 250 nm\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSize Range ( R h )\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eIn flow mode, 0.5 nm to 300 nm ; batch mode 0.5 nm to 1 μm \n(requires WyattQELS™ DLS module).\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eData Acquisition Rate\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eup to 300 measurements per minute\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eAccuracy\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e5%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eRepeatability\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e2%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eTemperature Options\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eultraDAWN: Ambient or heated\/cooled (HC) -15 °C to +150 °C ultraDAWN Pilot: ambient only\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSolvent Compatibility\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eAll-solvent compatible (aqueous and organic). Wetted materials are 316 stainless steel, fused silica and Kalrez.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMaximum Inline Flow Rate\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eultraDAWN: 150 mL\/min @  1 cP ultraDAWN Pilot: 1000 mL\/min @ 1 cP\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMaximum Viscosity\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e30 cP (when using HPLC pump with standard or heated\/cooled ultraDAWN in on-line configuration)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMALS Detectors\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eHigh-gain, high dynamic range photodiodes at 18 detection angles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eAnalog Inputs\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e4 analog input lines for external signals from -10V to +10V\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eAnalog Outputs\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e4 analog output lines for sending trigger signals to process equipment\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eOther Inputs\/Outputs\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eAlarm In, Alarm Out\/Retransmit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eComputer Interface\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eEthernet\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eFront Panel Display\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e10.1\" (257 mm), capacitive high-resolution screen with multi-touch functionality, displays signals, graphs, instrument settings and diagnostics. May be used with gloves.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDimensions\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e58 cm (L) x 36 cm (W) x 26 cm (H)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\u003cp\u003e\u003ca href=\"https:\/\/www.wyatt.com\/products\/ultradawn-brochure-request.html\" target=\"_blank\"\u003eBrochure\u003c\/a\u003e\u003c\/p\u003e","brand":"Wyatt Technology","offers":[{"title":"Ambient \/ No Attenuators \/ No QELS","offer_id":46488409964623,"sku":"WULD1-010000","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Ambient \/ No Attenuators \/ With QELS","offer_id":46488409997391,"sku":"WULD1-010001","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Ambient \/ Even Attenuators \/ No QELS","offer_id":46488410030159,"sku":"WULD1-010100","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Ambient \/ Even Attenuators \/ With QELS","offer_id":46488410062927,"sku":"WULD1-010101","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Ambient \/ All Attenuators \/ No QELS","offer_id":46488410095695,"sku":"WULD1-010200","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Ambient \/ All Attenuators \/ With QELS","offer_id":46488410128463,"sku":"WULD1-010201","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Ambient \/ To be specified \/ To be specified","offer_id":46488410161231,"sku":"WULD1","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Heated\/Cooled \/ No Attenuators \/ No QELS","offer_id":46488397283407,"sku":"WULD1T-010000","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Heated\/Cooled \/ Even Attenuators \/ No QELS","offer_id":46488410193999,"sku":"WULD1T-010100","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Heated\/Cooled \/ All Attenuators \/ No QELS","offer_id":46488410226767,"sku":"WULD1T-010200","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Heated\/Cooled \/ To be specified \/ To be specified","offer_id":46488410259535,"sku":"WULD1T","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/wyatt-ultradawn-ultradawn-pilot.webp?v=1787675360"},{"product_id":"wyatt-wyattqels-dynamic-light-scattering-module","title":"WyattQELS Dynamic Light Scattering Module","description":"\u003cp\u003eIntegrates inside a MALS to provide simultaneous DLS measurements of hydrodynamic radius (Rh) in the same scattering volume viewed by the MALS detectors; integration eliminates artifacts due to band broadening or temporal displacement between separate detectors.\nRequest More Information\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\u003cp\u003e\u003ca href=\"https:\/\/www.wyatt.com\/products\/dawn-brochure-request.html\" target=\"_blank\"\u003eBrochure\u003c\/a\u003e\u003c\/p\u003e","brand":"Wyatt Technology","offers":[{"title":"Default Title","offer_id":46488397643855,"sku":"WIQ","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/WIQ-A.jpg?v=1787675362"},{"product_id":"wyatt-dynapro-nanostar-ii-dynamic-light-scattering-ins","title":"DynaPro NanoStar II Dynamic Light Scattering Instrument","description":"\u003cspan\u003e\u003cp align=\"center\"\u003e\u003cimg src=\"\/wp-content\/uploads\/2022\/01\/NanoStar_Hero_Display.jpg\" alt=\"DynaPro NanoStar, dls instrument, dynamic light scattering instrument\" title=\"DynaPro NanoStar II\" width=\"50%\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003c\/p\u003e\u003c\/span\u003e\n\u003cp\u003eTraditional dynamic light scattering, just better.\u003c\/p\u003e\n\u003cp\u003eUnique cuvette-based DLS\u003c\/p\u003e\n\u003cp\u003eThe DynaPro NanoStar II is a unique cuvette-based DLS instrument used for the analysis of proteins, gene therapy vectors, viruses and virus-like particles, promiscuous inhibitors, micelles, liposomes, lipid and metallic nanoparticles, and more. To accommodate scarce and precious samples, specially designed quartz cuvettes afford robust, accurate measurements with as little as 2 µL of solution, while our proprietary disposable cuvettes provide comparable sensitivity with as little as 4 µL!\u003c\/p\u003e\n\u003chr class=\"no_line\" style=\"margin: 0 auto 10px auto\"\u003e\n\u003cp\u003eWalk-up operation with DYNAMICS Touch\u003csup\u003e™\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003eThe NanoStar is the only DLS instrument to provide a fully integrated, walk-up measurement experience. No need to boot up your lab PC, launch the DLS software, connect to the instrument and worry about where your data files are stored. DYNAMICS Touch is an intuitive—yet capable—DLS measurement app that resides right on the NanoStar. \nVia the full-size touch screen display, \u003ca href=\"https:\/\/www.wyatt.com\/products\/software\/dynamics-touch.html\"\u003eDYNAMICS Touch\u003c\/a\u003e guides you through the entire setup and measurement process. It tells you if the data quality is sufficient for confidence in the results, and displays them instantly. Data files and concise PDF reports can be stored on the instrument, transferred via the network or downloaded to a flash drive. You can even send the report to your phone!\u003c\/p\u003e\n\u003cp\u003eFull-featured analyses with DYNAMICS\u003csup\u003e™\u003c\/sup\u003e\u003c\/p\u003e\n\u003ca href=\"https:\/\/www.wyatt.com\/products\/software\/dynamics.html\"\u003eDYNAMICS\u003c\/a\u003e is our powerful PC-based, comprehensive software package for collecting, analyzing, and reporting batch dynamic and static light scattering data. It performs advanced analyses and compares multiple data files to identify trends and statistics. DYNAMICS can control the NanoStar and acquire data directly, or read in DYNAMICS Touch data files.\n\u003cp\u003eDYNAMICS is offered with a 21 CFR Part 11 compliant Security Pack option, enabling the use of the DynaPro NanoStar in a GMP environment for quality control or at-line process monitoring.\u003c\/p\u003e\n\u003cp\u003eSize and beyond\u003c\/p\u003e\n\u003cdiv class=\"column one-second\" style=\"padding-right:10px\"\u003e\n\u003cp\u003eCoupled with the versatile and user-friendly \u003ca href=\"https:\/\/www.wyatt.com\/products\/software\/dynamics.html\"\u003eDYNAMICS\u003csup\u003e™\u003c\/sup\u003e software\u003c\/a\u003e and \u003ca href=\"https:\/\/www.wyatt.com\/products\/software\/dynamics-touch.html\"\u003eDYNAMICS Touch\u003csup\u003e™\u003c\/sup\u003e\u003c\/a\u003e on-board app, the NanoStar may be utilized to measure not just size, size distributions, particle concentration and weight-average molar mass, but also solution properties relevant to sample stability: the second virial coefficient \n  (\u003ci\u003eA\u003c\/i\u003e\u003csub\u003e2\u003c\/sub\u003e or \u003ci\u003eB\u003c\/i\u003e\u003csub\u003e22\u003c\/sub\u003e), the diffusion interaction parameter (\u003ci\u003ek\u003c\/i\u003e\u003csub\u003eD\u003c\/sub\u003e), \u003ca href=\"https:\/\/www.wyatt.com\/solutions\/measuring-turbidity-opalescence.html\"\u003eturbidity or opalescence\u003c\/a\u003e and the temperature of protein melting or aggregation onset (\u003ci\u003eT\u003c\/i\u003e\u003csub\u003em\u003c\/sub\u003e, \u003ci\u003eT\u003c\/i\u003e\u003csub\u003eonset\u003c\/sub\u003e).\u003c\/p\u003e\n\u003cp\u003eCuvette, and yet...\u003c\/p\u003e\n\u003cp\u003e... still another feature unique to the NanoStar: the \u003ca href=\"https:\/\/store.wyatt.com\/shop\/udawn\/udawn3\/dls-compatibility-kit\/\"\u003eoptical fiber pickup\u003c\/a\u003e may be coupled to any of Wyatt's on-line MALS detectors - the \n  \u003ca href=\"https:\/\/www.wyatt.com\/products\/instruments\/dawn-multi-angle-light-scattering-detector.html\"\u003eDAWN\u003csup\u003e™\u003c\/sup\u003e\u003c\/a\u003e or \n  \u003ca href=\"https:\/\/www.wyatt.com\/products\/instruments\/minidawn-multi-angle-light-scattering-detector-sec-mals.html\"\u003eminiDAWN\u003csup\u003e™\u003c\/sup\u003e\u003c\/a\u003e - to add on-line DLS measurements in the same detection volume as \u003ca href=\"https:\/\/www.wyatt.com\/solutions\/techniques\/sec-mals-molar-mass-size-multi-angle-light-scattering.html\"\u003eSEC-MALS\u003c\/a\u003e or \u003ca href=\"https:\/\/www.wyatt.com\/solutions\/techniques\/fff-mals-characterization-of-nanoparticles-colloids-macromolecules.html\"\u003eFFF-MALS\u003c\/a\u003e measurements. \u003c\/p\u003e\n\u003cp\u003eCombining numerous benefits, the NanoStar is an unparalleled cuvette-based DLS detector. For higher productivity, consider the \n  \u003ca href=\"https:\/\/www.wyatt.com\/products\/instruments\/dynapro-dynamic-light-scattering-plate-reader.html\"\u003eDynaPro™\u003csup\u003e™\u003c\/sup\u003e Plate Reader\u003c\/a\u003e, the only commercially available DLS plate reader measuring \u003ci\u003ein situ\u003c\/i\u003e for high-throughput screening of thousands of conditions per day in industry-standard microwell plates.\u003c\/p\u003e\n\u003cp\u003eKey features\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eDYNAMICS Touch on-board app for walk-up operation\u003c\/li\u003e\n\u003cli\u003e\n\u003ci\u003eR\u003c\/i\u003e\u003csub\u003eh\u003c\/sub\u003e from 0.2 nm - 1000 nm\u003c\/li\u003e\n\u003cli\u003eTemperature from -10 °C to +120 °C\u003c\/li\u003e\n\u003cli\u003eMolecular weight from 300 Da to 1 MDa\u003c\/li\u003e\n\u003cli\u003eTurbidity from 1 to 80 NTU\u003c\/li\u003e\n\u003cli\u003eSeparate, optimized SLS and DLS detection channels\u003c\/li\u003e\n\u003cli\u003eAuto-attenuation over five orders of magnitude\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eVersatile, high-quality options\u003c\/p\u003e\n\u003cp\u003eMake measurements in super-high-quality quartz cuvettes with as little as 2 µL of sample, aqueous or organic solvents, over the entire, extended temperature range. This cuvette incorporates a solvent reservoir to prevent sample evaporation over high-temperature or extended analyses.\u003c\/p\u003e\n\u003cp\u003eOur proprietary disposable cuvettes nearly match the optical quality of quartz yet require only 4 µL of sample, aqueous or select polar solvents. For convenience, larger-volume \u003ca href=\"https:\/\/store.wyatt.com\/?product_cat=\u0026amp;post_type=product\u0026amp;s=cuvette\"\u003equartz\u003c\/a\u003e and disposable cuvettes are also available.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"column one-second\"\u003e\n\u003cp align=\"center\"\u003e\u003ca href=\"https:\/\/www.wyatt.com\/wp-content\/uploads\/2022\/01\/Dashboard-Page-Conc.jpg\" rel=\"lightbox\"\u003e\u003cimg alt=\"DYNAMICS Touch\" src=\"https:\/\/www.wyatt.com\/wp-content\/uploads\/2022\/01\/Dashboard-Page-Conc.jpg\" width=\"80%\"\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003cp align=\"center\" style=\"color:#075c97;font-size:14px\"\u003eClick to enlarge.\u003c\/p\u003e\n\u003cp align=\"center\"\u003e\u003cimg alt=\"Cuvettes\" src=\"https:\/\/www.wyatt.com\/wp-content\/uploads\/2021\/10\/Cuvettes.jpg\" style=\"padding-left:20px\" width=\"80%\"\u003e\u003c\/p\u003e\n\u003cbr\u003e\u003cbr\u003e\n\u003cp align=\"center\"\u003e\u003cimg alt=\"DYNAMICS Touch\" src=\"https:\/\/www.wyatt.com\/wp-content\/uploads\/2022\/01\/Over-Shoulder-Touch-Screen.jpg\" style=\"padding-left:20px\" width=\"80%\"\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSize Range (Radius)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e0.2 to 1000 nm\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eStatic Scattering Molecular Weight Range\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e300 Da to 10 MDa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eTurbidity Range\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e1 to 80 NTU\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eParticle Concentration Range\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e1x10 to 1x 10 (dependent on size)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSensitivity\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e0.1 mg\/mL of 14.4 kDa lysozyme in PBS\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eTemperature Range\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e-10 °C to +120 °C Maximum ramp rate 15 °C\/min\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSample Cells\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eQuartz cuvette: 2 μL or 45 μL, Disposable cuvette (cyclic olefin copolymer), generic 4 mL quartz\nand disposable cuvettes (with adapter)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMinimum Sample Volume\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e2 μL in quartz cuvette; 4 μL in disposable cuvette\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eLaser Wavelength\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e658 nm\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eLaser Power Control\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eProgrammable 10% to 100%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eScattering Angle\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e90°\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eOptical Fiber\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eMulti-mode\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eAdditional Detectors\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eLaser monitor for active stabilization; Forward monitor measures  transmitted light for turbidance and laser\/cell diagnostics\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eData Acquisition Time\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e1 to 3600 sec\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eCorrelator\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e512 channel, 100 nsec sampling time in a multi-tau layout\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDimensions\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e57 cm (L) x 36 cm (W) x 20 cm (H)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eWeight\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eTBD\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\u003cp\u003e\u003ca href=\"https:\/\/www.wyatt.com\/products\/nanostar-brochure-request.html\" target=\"_blank\"\u003eBrochure\u003c\/a\u003e\u003c\/p\u003e","brand":"Wyatt Technology","offers":[{"title":"Standalone \/ 2 µL \/ Active USB","offer_id":46488410292303,"sku":"WDN-0100","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Standalone \/ 2 µL \/ Disabled USB","offer_id":46488410325071,"sku":"WDN-0101","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Standalone \/ 45 µL \/ Active USB","offer_id":46488410357839,"sku":"WDN-0200","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Standalone \/ 45 µL \/ Disabled USB","offer_id":46488410390607,"sku":"WDN-0201","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Standalone \/ To be specified \/ To be specified","offer_id":46488410423375,"sku":"WDN","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"With MALS interface \/ 2 µL \/ Active USB","offer_id":46488410456143,"sku":"WDNM-0100","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"With MALS interface \/ 2 µL \/ Disabled USB","offer_id":46488410488911,"sku":"WDNM-0101","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"With MALS interface \/ 45 µL \/ Active USB","offer_id":46488410521679,"sku":"WDNM-0200","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"With MALS interface \/ 45 µL \/ Disabled USB","offer_id":46488410554447,"sku":"WDNM-0201","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"With MALS interface \/ To be specified \/ To be specified","offer_id":46488410587215,"sku":"WDNM","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/NanoStar_Hero_Display.jpg?v=1787675364"},{"product_id":"wyatt-dynapro-zetastar-dls-els-instrument","title":"DynaPro ZetaStar DLS \u0026 ELS Instrument","description":"\u003cbr\u003e\n\u003cp\u003eWalk-up or automated measurements of size,\nparticle concentration and zeta potential\u003c\/p\u003e\n\u003cp\u003eMulti-measurement capabilities in one instrument\u003c\/p\u003e\n\u003cp\u003eThe DynaPro\u003csup\u003e™\u003c\/sup\u003e ZetaStar combines dynamic, electrophoretic and static light scattering to characterize nanoparticle suspensions and macromolecular solutions. It is simple to use, but a powerful tool that quickly delivers size and polydispersity, zeta potential, particle concentration, molar mass, and turbidity\/opalescence for molecules that range in size from angstroms to microns. Analyze and quantify viral vectors, vesicles, lipid nanoparticles, inorganic nanoparticles, nanoemulsions, polymers, peptides, proteins, nucleic acids, and more. \u003c\/p\u003e\n\u003cp\u003eAutomated nanoparticle characterization\u003c\/p\u003e\n\u003cp\u003eThe DynaPro™ ZetaStar Instrument stands apart from other light scattering devices with its unique ability to fully automate size and zeta potential measurements. When paired to an HPLC autosampler, achieve precise, unattended analysis on up to 96 samples in a single run—saving time and reducing variability.\u003c\/p\u003e\n\u003cp\u003eWalk-up operation with DYNAMICS Touch\u003csup\u003e™\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003eDesigned for casual and non-expert users, \u003ca href=\"https:\/\/www.wyatt.com\/products\/software\/dynamics-touch.html\"\u003eDYNAMICS Touch\u003c\/a\u003e is an intuitive—yet capable—multi-measurement app that resides right on the ZetaStar. Via the touch screen display, DYNAMICS Touch guides measurement setup and data collection. Data quality indicators provide confidence in the results as well as insight to help improve future measurements. Results are instantly displayed on the ZetaStar, while data files and concise PDF reports can be stored on the instrument, transferred via the network or downloaded to a flash drive. You can even send the report to your phone!\u003c\/p\u003e\n\u003cp\u003eFull-featured analyses with DYNAMICS™\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/www.wyatt.com\/products\/software\/dynamics.html\"\u003eDYNAMICS\u003c\/a\u003e is our powerful PC-based, comprehensive software package for collecting, analyzing, and reporting dynamic, static and electrophoretic light scattering data. It performs advanced analyses and compares multiple data files to identify trends and compile statistics. DYNAMICS can control the ZetaStar and acquire data directly, run a series of automated experiments with an autosampler, or read in DYNAMICS Touch data files.\u003c\/p\u003e\n\u003cp\u003eDYNAMICS is offered with a 21 CFR Part 11 compliant Security Pack option, enabling the use of the ZetaStar in a GMP environment for quality control or at-line process monitoring.\u003c\/p\u003e\n\u003cdiv class=\"column one-second mobile-one\"\u003e\u003cdiv class=\"mcb-column-inner\"\u003e\n\u003cp style=\"color:#075c97;\"\u003eMore than just your typical zeta potential detector\u003c\/p\u003e\n\u003cp\u003eUnique among zeta potential detectors, the ZetaStar offers sensitive and robust DLS, ELS, and SLS measurements both in cuvettes and in automation using a flow cell.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cb\u003eDLS\/ELS\u003c\/b\u003e: The ZetaStar performs simultaneous dynamic and electrophoretic light scattering (DLS\/ELS) to determine size, polydispersity and zeta potential. \u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eDLS\/SLS\u003c\/b\u003e: Simultaneous dynamic and static light scattering (DLS\/SLS) enables size, polydispersity, particle concentration, molar mass and\/or turbidity measurements in as little as 2 µL. \u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eAutomation\u003c\/b\u003e: The ZetaStar can be paired with an HPLC autosampler and pump to automate measurements of zeta potential and size for up to -96 samples at a time.\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eConvenience\u003c\/b\u003e: DLS\/ELS and DLS\/SLS can also be carried out  in disposable cells to eliminate cuvette cleaning operations and potential sample carryover.\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eLow volume\u003c\/b\u003e: DLS\/ELS can be performed with as little as  65 µL of solution, and DLS\/SLS with as little as 2 µL. \u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eSpeed\u003c\/b\u003e: DLS\/ELS measurements can take just 15 seconds, and DLS\/SLS measurements even less.\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eHigh salt\u003c\/b\u003e: ZetaStar can measure zeta potential in solutions representative of physiological conditions or formulation buffers with high sensitivity and no damage to fragile biological samples .\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\u003c\/div\u003e\n\u003cdiv class=\"column one-second mobile-one\"\u003e\u003cdiv class=\"mcb-column-inner\"\u003e\n\u003cdiv style=\"padding:0px 30px 0px 30px\"\u003e\n\u003cp align=\"center\"\u003e\u003cimg alt=\"ZetaStar\" class=\"scale-with-grid\" src=\"https:\/\/www.wyatt.com\/wp-content\/uploads\/2023\/09\/DynaPro-ZetaStar-Hero-View.jpg\"\u003e\u003c\/p\u003e\n\u003cp align=\"center\"\u003e \u003cimg alt=\"zetastar\" src=\"https:\/\/www.wyatt.com\/wp-content\/uploads\/2023\/09\/ZetaStar-Properties-Panels-1000.jpg\"\u003e \u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\u003c\/div\u003e\n\u003chr class=\"no_line\" style=\"margin: 0 auto 0px auto\"\u003e\n\u003cdiv class=\"column one-second mobile-one\"\u003e\u003cdiv class=\"mcb-column-inner\"\u003e\n\u003cp\u003e\u003cb\u003eQuick and easy\u003c\/b\u003e: Coupled with the user-friendly on-board app, DYNAMICS Touch\u003csup\u003e™\u003c\/sup\u003e, quick and robust results are just a few clicks away. \u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eMaximum power\u003c\/b\u003e: Paired with the full power of PC-based DYNAMICS\u003csup\u003e™\u003c\/sup\u003e, the ZetaStar can determine extended solution properties including:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cb\u003eColloidal stability\u003c\/b\u003e: second virial coefficient (\u003ci\u003eA\u003c\/i\u003e\u003csub\u003e2\u003c\/sub\u003e or \u003ci\u003eB\u003c\/i\u003e\u003csub\u003e22\u003c\/sub\u003e) and  diffusion interaction parameter (\u003ci\u003ek\u003c\/i\u003e\u003csub\u003eD\u003c\/sub\u003e), turbidity or opalescence\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eThermal stability\u003c\/b\u003e: temperature of protein melting or aggregation onset (\u003ci\u003eT\u003c\/i\u003e\u003csub\u003em\u003c\/sub\u003e, \u003ci\u003eT\u003c\/i\u003e\u003csub\u003eonset\u003c\/sub\u003e, \u003ci\u003eT\u003c\/i\u003e\u003csub\u003eagg\u003c\/sub\u003e)\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eAccelerate degradation kinetics\u003c\/b\u003e: the evolution of size and molar mass with time at elevated temperature.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eMinimum downtime\u003c\/b\u003e: Constructed of a set of field-replaceable modules with no need for optical alignment, the ZetaStar need never leave your lab for maintenance. A Wyatt technician can make most repairs on-site.\u003c\/p\u003e\n\u003c\/div\u003e\u003c\/div\u003e\n\u003cdiv class=\"column one-second mobile-one\"\u003e\u003cdiv class=\"mcb-column-inner\"\u003e\n\u003cdiv style=\"padding:0px 30px 0px 30px\"\u003e\n\u003cp align=\"center\" style=\"padding-top:20px\"\u003e \u003cimg alt=\"zetastar\" src=\"https:\/\/www.wyatt.com\/wp-content\/uploads\/2023\/09\/zetastar-description.jpg\" width=\"100%\"\u003e \u003c\/p\u003e\n\u003cp align=\"left\" style=\"color:#075c97;font-size:14px;\"\u003eZetaStar features an intuitive onboard app, DYNAMICS Touch, which enables anyone to walk up to the instrument, insert a cuvette with sample and be guided through a measurement.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\u003c\/div\u003e\n\u003chr class=\"no_line\" style=\"margin: 0 auto 0px auto\"\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSize Range (Radius)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e0.2 nm to 1 μm (cuvette); 0.2 nm to 400 nm (flow cell)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSize Sensitivity\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e0.1 mg\/mL lysozyme (DLS 90); 1 mg\/mL lysozyme (DLS backscattering)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eTemperature Range\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e-10 ºC to 120 ºC*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDetection Angle\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e90º (sidescattering) \u0026amp; 163.5º (backscattering)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMolecular Weight Range\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e300 Da to 10 MDa**\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eParticle Concentration Max Size\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e225 nm\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eParticle Concentration Range\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e10 to 10 particles\/mL (dependent on particle size)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eTurbidity Range\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e1 to 100 NTU\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMolecular Weight Sensitivity\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e0.1 mg\/mL lysozyme\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSLS Measurements Temperature Range\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e-10 ºC to 120 ºC*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSLS Measurements Detection Angle\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e90º\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eConductivity Range\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e0 to 250 mS\/cm***\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMobility Range\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e“No practical limit”\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMobility Size Range\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e1 nm to 50 µm\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMobility Sensitivity\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e1 mg\/mL lysozyme\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eELS Measurements Temperature Range\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e4 ºC to 70 ºC*\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eELS Measurements Detection Angle\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e10º\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eFlow Cell\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003ePEEK, platinum, quartz\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eZeta Disposable Cell\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eCyclic olefin copolymer, polypropylene, 316 stainless steel\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDip Cell\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eQuartz, platinum, polyurethane\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDLS Disposable Cuvette\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eCyclic olefin copolymer\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eLaser Power Control\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eProgrammable 10% to 100%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eLaser Wavelength\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e785 nm\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDetectors\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eELS, SLS, and DLS detectors\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eAdditional Detectors\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eLaser monitor for active compensation; Forward monitor measures\ntransmitted light for turbidance and laser\/cell diagnostics\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eData Acquisition Time\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e1 to 3600 sec\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eCorrelator\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e512 channel, 100 nsec sampling time in a multi-tau layout\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eAuxiliary I\/O\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eAuto Inject contact closure,\n2 analog inputs (16 bits, +\/- 10 V)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eUSB\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e4 USB ports\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eCommunications\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eEthernet\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eFront Panel Display\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e162.5 mm, 16-bit, high-resolution touch screen displays signal graphs, instrument settings, and diagnostics\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDimensions\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e57 cm (L) x 36 cm (W) x 20 cm (H)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\u003cp\u003e\u003ca href=\"https:\/\/www.wyatt.com\/products\/zetastar-brochure-request.html\" target=\"_blank\"\u003eBrochure\u003c\/a\u003e\u003c\/p\u003e","brand":"Wyatt Technology","offers":[{"title":"Standard","offer_id":46488398037071,"sku":"WDZ","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Active USB","offer_id":46488398069839,"sku":"WDZ-00","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Disabled USB","offer_id":46488398102607,"sku":"WDZ-01","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/DynaPro-ZetaStar-Hero-View.jpg?v=1787675366"},{"product_id":"wyatt-dynapro-plate-reader-iii","title":"DynaPro Plate Reader III","description":"\u003cspan\u003e\u003cp align=\"center\"\u003e\u003cimg src=\"https:\/\/www.wyatt.com\/wp-content\/uploads\/2025\/08\/PR4-Hero-1000.webp\" width=\"500px\"\u003e\u003c\/p\u003e\u003c\/span\u003e\n\u003cp\u003eHigh-throughput, automated, dynamic and static light scattering\u003c\/p\u003e\n\u003cp\u003eUpgrade to plates\u003c\/p\u003e\n\u003cp\u003eRevolutionize your performance by replacing your conventional, cuvette-based dynamic light scattering unit with the automated DynaPro Plate Reader. The DynaPro excels at high-throughput sizing and screening of pharmaceutical and nanoparticle formulations to enable novel workflows that simply would not be possible with other DLS instruments. Even if you need to run just a handful of samples, it's a great productivity booster. \u003c\/p\u003e\n\u003chr class=\"no_line\" style=\"margin: 0 auto 10px auto\"\u003e\n\u003cp\u003eWalk-up operation with DYNAMICS Touch\u003csup\u003e™\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003eThe DynaPro Plate Reader is the only plate-based DLS instrument with a fully integrated, walk-up measurement experience. DYNAMICS Touch is an intuitive—yet powerful—DLS measurement app for collecting, analyzing, and reporting dynamic and static light scattering data. Via the full-size touch screen display, \u003ca href=\"https:\/\/www.wyatt.com\/products\/software\/dynamics-touch.html\"\u003eDYNAMICS Touch\u003c\/a\u003e guides you through the entire setup and measurement process, expertise not required. It tells you if the data quality is sufficient for confidence in the results and displays them instantly, no matter how many wells you measure. Data files and concise PDF reports can be stored on the instrument or transferred via the network. You can even send the report to your phone!\n\u003c\/p\u003e\u003cp\u003eComprehensive solution\u003c\/p\u003e\n\u003cp\u003eFor biotherapeutic development, the DynaPro Plate Reader is a comprehensive solution for stability evaluation. Measure aggregation, aggregate size distributions, changes in solution molecular weight, and propensity for aggregation: indicators of both thermal stability (T\u003csub\u003eonset\u003c\/sub\u003e, T\u003csub\u003em\u003c\/sub\u003e, T\u003csub\u003eagg\u003c\/sub\u003e) and colloidal stability (A\u003csub\u003e2\u003c\/sub\u003e\/B\u003csub\u003e22\u003c\/sub\u003e, k\u003csub\u003eD\u003c\/sub\u003e) may be quantified with plate-based DLS and SLS. Even viscosity of concentrated protein solutions can be screened across dozens of formulations in a single plate.\u003c\/p\u003e\n\u003cp\u003eFor nanoparticle formulation and process development, including  viral vectors, non-viral vectors and nano-drug delivery vehicles, the DynaPro adds particle concentration \/ physical titer to basic DLS measurements of size and polydispersity. Its automation is particularly valued to screen fractions during process development and then to quantify CQAs in quality control.\u003c\/p\u003e\n\u003chr class=\"no_line\" style=\"margin: 0 auto 10px auto\"\u003e\n\u003cp\u003eCompatible with DYNAMICS\u003csup\u003e™\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003eThe DynaPro Plate Reader is operated by \u003ca href=\"https:\/\/www.wyatt.com\/products\/software\/dynamics.html\"\u003eDYNAMICS\u003c\/a\u003e, our powerful software package for collecting, analyzing, and reporting automated batch dynamic and static light scattering data. \u003c\/p\u003e\n\u003cp\u003eDYNAMICS is offered with a 21 CFR Part 11 compliant Security Pack option, enabling the use of the DynaPro Plate Reader in a GMP environment.\u003c\/p\u003e\n\u003cp\u003eRevolutionize DLS\u003c\/p\u003e\n\u003cp\u003eThe DynaPro Plate Reader offers dynamic light scattering (DLS) and static light scattering (SLS) measurements of the size, molecular weight, concentration and interactions of proteins, nanoparticles and other macromolecules \u003ci\u003ein situ\u003c\/i\u003e in industry-standard microwell plates. No liquid handling occurs after dispensing into the plates, to maximize throughput and minimize sample carryover. This ground-breaking instrument provides rapid optimization of the formulation process for:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/www.wyatt.com\/solutions\/applications\/biotherapeutics-biophysical-characterization-aggregation-quality.html\"\u003eBiotherapeutics\u003c\/a\u003e such as monoclonal antibodies and virus-like particles (VLPs)\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/www.wyatt.com\/solutions\/applications\/nanoparticle-characterization-by-multi-angle-and-dynamic-light-scattering.html\"\u003eNanoparticle\u003c\/a\u003e drug delivery vehicles including liposomes and conjugated gold NPs\u003c\/li\u003e\n\u003cli\u003eViral and non-viral gene vectors like \u003ca href=\"https:\/\/www.wyatt.com\/GeneTherapy.html\"\u003eAAV, adenovirus, lentivirus\u003c\/a\u003e and \u003ca href=\"https:\/\/www.wyatt.com\/solutions\/lipid-nanoparticle-characterization.html\"\u003eLNP\u003c\/a\u003e\n\u003c\/li\u003e \u003c\/ul\u003e\n\u003cbr\u003e\n\u003cp\u003eA wealth of applications\u003c\/p\u003e\n\u003cp\u003eThe DynaPro Plate Reader provides unparalleled levels of ease-of-use, productivity, reproducibility, and flexibility in order to address additional demanding applications such as:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eAssessing aggregation or oligomerization\u003c\/li\u003e\n\u003cli\u003eQuantifying AAV titer for multiple processes\u003c\/li\u003e\n\u003cli\u003eDetermining protein stability-indicating parameters such as thermal denaturation and colloidal stability\u003c\/li\u003e\n\u003cli\u003eOptimizing protein crystallization\u003c\/li\u003e\n\u003cli\u003eScreening high-concentration protein solutions for reversible association and viscosity\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/wyattfiles.s3-us-west-2.amazonaws.com\/literature\/app-notes\/dls-plate\/WP5003-Automated-dynamic-and-static-light-scattering-in-microwell-plates.pdf\" target=\"_blank\"\u003eRead White Paper\u003c\/a\u003e\u003c\/p\u003e\n\u003cbr\u003e\n\u003cp\u003eKey features\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eMeasure hydrodynamic radius from 0.5 nm to 1000 nm\u003c\/li\u003e\n\u003cli\u003eDetermine particle concentration for particles up to 320 nm in diameter\u003c\/li\u003e\n\u003cli\u003eSensitivity for size down to 0.125 mg\/mL lysozyme\u003c\/li\u003e\n\u003cli\u003eMeasure weight-average molar mass from 1 to 1000 kDa\u003c\/li\u003e\n\u003cli\u003eIndustry-standard microwell plates of 96, 384 or 1536 wells\u003c\/li\u003e\n\u003cli\u003eSample volume from 4 μL to 150 μL\u003c\/li\u003e\n\u003cli\u003eAll measurements made \u003ci\u003ein situ\u003c\/i\u003e in the wells\u003c\/li\u003e\n\u003cli\u003eTemperature ramps from 4 °C to 85 °C\u003c\/li\u003e\n\u003cli\u003eIntegrates with plate-based liquid handling robotics\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSupported Well Plate Formats\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e96, 384 or 1536 *\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSize Range (Radius, R h )\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e0.5 to 1000 nm\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMinimum Concentration @ 14 kDa\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e0.125 mg\/mL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMolar Mass Range\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e300 Da to 1 MDa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMinimum Concentration @ 67 kDa\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e1 mg\/mL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eLaser Wavelength\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e830 nm\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eLaser Power Control\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eProgrammable 10% – 100%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eAttenuation Range\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e1 to 10\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eTemperature Control\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e4 to 85 °C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMinimum Sample Volume\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e4 µL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eData Acquisition Time\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e1 to 3600 seconds per well per read\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eRead Time per Well\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e5 – 20 seconds\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eCorrelator\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e512 channels\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eOnboard Camera\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e3 megapixels\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDigital Communication\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eEthernet (TCP\/IP)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDimensions\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e60 cm (L) x 36 cm (W) x 25 cm (H)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\u003cp\u003e\u003ca href=\"https:\/\/www.wyatt.com\/products\/plate-reader-brochure-request.html\" target=\"_blank\"\u003eBrochure\u003c\/a\u003e\u003c\/p\u003e","brand":"Wyatt Technology","offers":[{"title":"Standard","offer_id":46488398200911,"sku":"WPR3","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Cat. WPR3-01","offer_id":46488398233679,"sku":"WPR3-01","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/PR4-Hero-1000.webp?v=1787675370"},{"product_id":"wyatt-dynapro-plate-reader-4","title":"DynaPro Plate Reader 4","description":"\u003cspan\u003e\u003cp align=\"center\"\u003e\u003cimg src=\"https:\/\/www.wyatt.com\/wp-content\/uploads\/2025\/08\/PR4-Hero-1000.webp\" width=\"500px\"\u003e\u003c\/p\u003e\u003c\/span\u003e\n\u003cp\u003eHigh-throughput, automated, dynamic and static light scattering\u003c\/p\u003e\n\u003cp\u003eUpgrade to plates\u003c\/p\u003e\n\u003cp\u003eRevolutionize your performance by replacing your conventional, cuvette-based dynamic light scattering unit with the automated DynaPro Plate Reader. The DynaPro excels at high-throughput sizing and screening of pharmaceutical and nanoparticle formulations to enable novel workflows that simply would not be possible with other DLS instruments. Even if you need to run just a handful of samples, it's a great productivity booster. \u003c\/p\u003e\n\u003chr class=\"no_line\" style=\"margin: 0 auto 10px auto\"\u003e\n\u003cp\u003eWalk-up operation with DYNAMICS Touch\u003csup\u003e™\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003eThe DynaPro Plate Reader is the only plate-based DLS instrument with a fully integrated, walk-up measurement experience. DYNAMICS Touch is an intuitive—yet powerful—DLS measurement app for collecting, analyzing, and reporting dynamic and static light scattering data. Via the full-size touch screen display, \u003ca href=\"https:\/\/www.wyatt.com\/products\/software\/dynamics-touch.html\"\u003eDYNAMICS Touch\u003c\/a\u003e guides you through the entire setup and measurement process, expertise not required. It tells you if the data quality is sufficient for confidence in the results and displays them instantly, no matter how many wells you measure. Data files and concise PDF reports can be stored on the instrument or transferred via the network. You can even send the report to your phone!\n\u003c\/p\u003e\u003cp\u003eComprehensive solution\u003c\/p\u003e\n\u003cp\u003eFor biotherapeutic development, the DynaPro Plate Reader is a comprehensive solution for stability evaluation. Measure aggregation, aggregate size distributions, changes in solution molecular weight, and propensity for aggregation: indicators of both thermal stability (T\u003csub\u003eonset\u003c\/sub\u003e, T\u003csub\u003em\u003c\/sub\u003e, T\u003csub\u003eagg\u003c\/sub\u003e) and colloidal stability (A\u003csub\u003e2\u003c\/sub\u003e\/B\u003csub\u003e22\u003c\/sub\u003e, k\u003csub\u003eD\u003c\/sub\u003e) may be quantified with plate-based DLS and SLS. Even viscosity of concentrated protein solutions can be screened across dozens of formulations in a single plate.\u003c\/p\u003e\n\u003cp\u003eFor nanoparticle formulation and process development, including  viral vectors, non-viral vectors and nano-drug delivery vehicles, the DynaPro adds particle concentration \/ physical titer to basic DLS measurements of size and polydispersity. Its automation is particularly valued to screen fractions during process development and then to quantify CQAs in quality control.\u003c\/p\u003e\n\u003chr class=\"no_line\" style=\"margin: 0 auto 10px auto\"\u003e\n\u003cp\u003eCompatible with DYNAMICS\u003csup\u003e™\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003eThe DynaPro Plate Reader is operated by \u003ca href=\"https:\/\/www.wyatt.com\/products\/software\/dynamics.html\"\u003eDYNAMICS\u003c\/a\u003e, our powerful software package for collecting, analyzing, and reporting automated batch dynamic and static light scattering data. \u003c\/p\u003e\n\u003cp\u003eDYNAMICS is offered with a 21 CFR Part 11 compliant Security Pack option, enabling the use of the DynaPro Plate Reader in a GMP environment.\u003c\/p\u003e\n\u003cp\u003eRevolutionize DLS\u003c\/p\u003e\n\u003cp\u003eThe DynaPro Plate Reader offers dynamic light scattering (DLS) and static light scattering (SLS) measurements of the size, molecular weight, concentration and interactions of proteins, nanoparticles and other macromolecules \u003ci\u003ein situ\u003c\/i\u003e in industry-standard microwell plates. No liquid handling occurs after dispensing into the plates, to maximize throughput and minimize sample carryover. This ground-breaking instrument provides rapid optimization of the formulation process for:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/www.wyatt.com\/solutions\/applications\/biotherapeutics-biophysical-characterization-aggregation-quality.html\"\u003eBiotherapeutics\u003c\/a\u003e such as monoclonal antibodies and virus-like particles (VLPs)\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/www.wyatt.com\/solutions\/applications\/nanoparticle-characterization-by-multi-angle-and-dynamic-light-scattering.html\"\u003eNanoparticle\u003c\/a\u003e drug delivery vehicles including liposomes and conjugated gold NPs\u003c\/li\u003e\n\u003cli\u003eViral and non-viral gene vectors like \u003ca href=\"https:\/\/www.wyatt.com\/GeneTherapy.html\"\u003eAAV, adenovirus, lentivirus\u003c\/a\u003e and \u003ca href=\"https:\/\/www.wyatt.com\/solutions\/lipid-nanoparticle-characterization.html\"\u003eLNP\u003c\/a\u003e\n\u003c\/li\u003e \u003c\/ul\u003e\n\u003cbr\u003e\n\u003cp\u003eA wealth of applications\u003c\/p\u003e\n\u003cp\u003eThe DynaPro Plate Reader provides unparalleled levels of ease-of-use, productivity, reproducibility, and flexibility in order to address additional demanding applications such as:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eAssessing aggregation or oligomerization\u003c\/li\u003e\n\u003cli\u003eQuantifying AAV titer for multiple processes\u003c\/li\u003e\n\u003cli\u003eDetermining protein stability-indicating parameters such as thermal denaturation and colloidal stability\u003c\/li\u003e\n\u003cli\u003eOptimizing protein crystallization\u003c\/li\u003e\n\u003cli\u003eScreening high-concentration protein solutions for reversible association and viscosity\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/wyattfiles.s3-us-west-2.amazonaws.com\/literature\/app-notes\/dls-plate\/WP5003-Automated-dynamic-and-static-light-scattering-in-microwell-plates.pdf\" target=\"_blank\"\u003eRead White Paper\u003c\/a\u003e\u003c\/p\u003e\n\u003cbr\u003e\n\u003cp\u003eKey features\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eMeasure hydrodynamic radius from 0.5 nm to 1000 nm\u003c\/li\u003e\n\u003cli\u003eDetermine particle concentration for particles up to 320 nm in diameter\u003c\/li\u003e\n\u003cli\u003eSensitivity for size down to 0.125 mg\/mL lysozyme\u003c\/li\u003e\n\u003cli\u003eMeasure weight-average molar mass from 1 to 1000 kDa\u003c\/li\u003e\n\u003cli\u003eIndustry-standard microwell plates of 96, 384 or 1536 wells\u003c\/li\u003e\n\u003cli\u003eSample volume from 4 μL to 150 μL\u003c\/li\u003e\n\u003cli\u003eAll measurements made \u003ci\u003ein situ\u003c\/i\u003e in the wells\u003c\/li\u003e\n\u003cli\u003eTemperature ramps from 4 °C to 85 °C\u003c\/li\u003e\n\u003cli\u003eIntegrates with plate-based liquid handling robotics\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSupported Well Plate Formats\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e96, 384 or 1536 *\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSize Range (Radius, R h )\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e0.5 to 1000 nm\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMinimum Concentration @ 14 kDa\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e0.125 mg\/mL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMolar Mass Range\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e300 Da to 1 MDa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMinimum Concentration @ 67 kDa\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e1 mg\/mL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eLaser Wavelength\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e830 nm\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eLaser Power Control\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eProgrammable 10% – 100%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eAttenuation Range\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e1 to 10\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eTemperature Control\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e4 to 85 °C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMinimum Sample Volume\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e4 µL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eData Acquisition Time\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e1 to 3600 seconds per well per read\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eRead Time per Well\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e5 – 20 seconds\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eCorrelator\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e512 channels\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eOnboard Camera\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e3 megapixels\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDigital Communication\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eEthernet (TCP\/IP)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDimensions\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e60 cm (L) x 36 cm (W) x 25 cm (H)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\u003cp\u003e\u003ca href=\"https:\/\/www.wyatt.com\/products\/plate-reader-brochure-request.html\" target=\"_blank\"\u003eBrochure\u003c\/a\u003e\u003c\/p\u003e","brand":"Wyatt Technology","offers":[{"title":"Default Title","offer_id":46488398266447,"sku":"WPR4-01","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/PR4-Hero-1000.webp?v=1787675370"},{"product_id":"wyatt-microoptilab-refractive-index-detector-for-uhplc","title":"microOptilab Refractive Index Detector for UHPLC","description":"\u003cspan\u003e\u003cp align=\"center\"\u003e\u003cimg alt=\"Optilab refractometer\" class=\"scale-with-grid\" src=\"https:\/\/www.wyatt.com\/wp-content\/uploads\/2019\/10\/microOptilab-Hero-Neon-10-2-19.jpg\" width=\"65%\"\u003e\u003c\/p\u003e\u003c\/span\u003e\n\u003cp\u003eUniversal Detection for UHPLC and SEC-MALS\n\u003c\/p\u003e\u003cp\u003eIndependent of Chromaphores\u003c\/p\u003e\n\u003cp\u003eIndependent of chromaphores or fluorophores, differential Refractive Index (dRI) detectors measure concentrations of all types of samples in almost all solvents. The microOptilab brings the universal detection capabilities, unsurpassed concentration range, and superb sensitivity and linearity – familiar from the \u003ca href=\"https:\/\/www.wyatt.com\/products\/instruments\/optilab-refractive-index-detector.html\"\u003eOptilab\u003csup\u003e™\u003c\/sup\u003e\u003c\/a\u003e – to the domain of UHPLC.\u003c\/p\u003e\n\u003chr class=\"no_line\" style=\"margin: 0 auto 10px auto\"\u003e\n\u003cp\u003eApplication Note\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/wyattfiles.s3.us-west-2.amazonaws.com\/literature\/app-notes\/sec-mals-proteins\/absolute-molar-mass-uhplc.pdf\" target=\"_blank\"\u003e\u003ci class=\"fa fa-file-pdf-o fa-lg\"\u003e\u003c\/i\u003eDownload our Application Note on the microOptilab\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eSEC-MALS with UHPLC\u003c\/p\u003e\n\u003cp\u003eLike standard SEC, UHPLC-SEC analysis relying on column calibration with molecular standards is unreliable when the standards do not accurately reflect your samples in terms of conformation, non-ideal (e.g., hydrophobic) column interactions or reversible association. \u003cb\u003eSEC-MALS\u003c\/b\u003e employs a \u003ca href=\"https:\/\/www.wyatt.com\/products\/instruments\/microDawn-multi-angle-detector-uhplc-sec-mals.html\"\u003emicroDAWN\u003csup\u003e™\u003c\/sup\u003e\u003c\/a\u003e MALS detector downstream of the SEC column and UV detector, to determine molar mass \/ molecular weight distributions of macromolecules independently of column calibration.\u003c\/p\u003e\n\u003cp\u003eRefractive index detection is an important component of any SEC-MALS system, and necessary for analyzing conjugated proteins or polymers devoid of chromaphores. The microOptilab connects with the microDAWN MALS detector for a complete UHP-SEC-MALS setup that transfers the many benefits of SEC-MALS analysis to the realm of UHPLC.\u003c\/p\u003e\n\u003cp\u003eKey benefits\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eVery low band broadening, \u0026lt; 4 µL, to maintain the resolution of very narrow UHPLC peaks\u003c\/li\u003e\n\u003cli\u003eExtraordinary dRI measurement range, -4.7 x 10\u003csup\u003e-3\u003c\/sup\u003e to +4.7 x 10\u003csup\u003e-3\u003c\/sup\u003e RIU (comparable to 25 mg\/mL protein in PBS)\u003c\/li\u003e\n\u003cli\u003eHighly sensitive, ± 1.5 x 10\u003csup\u003e-9\u003c\/sup\u003e RIU across the \u003ci\u003eentire\u003c\/i\u003e measurement range\u003c\/li\u003e\n\u003cli\u003eMeasures solvent refractive index, require for MALS calculations\u003c\/li\u003e\n\u003cli\u003eMeasures at the same wavelength as the MALS detector, for maximum accuracy in MALS calculations\u003c\/li\u003e\n\u003cli\u003eTemperature range 4 °C to 65 °C for proteins and polymers that require a range of temperatures\u003c\/li\u003e\n\u003cli\u003eHigh-resolution, touch-screen front panel displays data graphs and instrument diagnostics, even with the host computer turned off\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eUnparalleled features\u003c\/p\u003e\n\u003cp\u003eConsidering the extremely small peak volumes of UHPLC, band broadening in the microOptilab is kept to the absolute minimum, at less than 4 µL, as compared to 20 - 40 µL or more for standard RI detectors. As a result, the superior resolution from UHPLC columns and instruments will not be compromised with the microOptilab RI detector.\u003c\/p\u003e\n\u003cp\u003eEven though the microOptilab offers a dRI measurement range orders of magnitude beyond that of other UHPLC dRI detectors, unlike other detectors there are no range or gain settings in the microOptilab. The \u003ci\u003efull\u003c\/i\u003e range of instrument detection is always present, and the full sensitivity exists over the \u003ci\u003eentire\u003c\/i\u003e range. The small flow cell and proprietary temperature regulation enable stable RI baselines and signals which further enhance the detector's sensitivity.\u003c\/p\u003e\n\u003cp\u003eUnlike all other dRI detectors, the microOptilab also measures absolute refractive index in order to determine solvent RI, necessary in light scattering calculations and useful in assessing the accuracy of mixing of solvent gradients.\u003c\/p\u003e\n\u003cp\u003eThe microOptilab can be operated \u003ci\u003ebelow\u003c\/i\u003e ambient temperatures as easily as above ambient. No hassle temperature control can be programmed down to 4 °C or as high as 65 °C.\u003c\/p\u003e\n\u003cp\u003eThe microOptilab is compatible with \u003ci\u003eall\u003c\/i\u003e UHPLC systems.\u003c\/p\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eRange (RIU)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e-0.0047 to +0.0047\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003ePeak-to-peak noise (RIU)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e± 1.5 x 10\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eResponse Time\n(User Selectable)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e0.04 to 5 seconds\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eAbsolute Refractive Index Range (RIU)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e1.2 to 1.8\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSensitivity (RIU)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e± 0.002\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eBand Broadening\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u0026lt; 4 μL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eFill Volume (inlet tubing + flow cell)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e13.7 μL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eOutlet tubing (0.030\" ID)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e228 μL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eBack pressure created at inlet port (@ 0.5 mL\/min H2O, 20 °C)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u0026lt;320 psi (22 bar)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMaximum permissible back pressure allowed at outlet port\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e30 psi (2 bar)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eControl Range\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e4 °C to 65 °C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eRegulation\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e± 0.005 °C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eLight Source\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e660 nm\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSafety Sensors\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eVapor and liquid (leak)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDigital Output\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e25 Hz\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eAnalog Output\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e± 10 V or ± 1 V output, 18 bits resolution\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eComputer Interface\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eEthernet\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eFront Panel Display\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e7\" (178 mm), high-resolution, multi-touch display for viewing\/setting signals, instrument settings and diagnostics\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eInputs\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eAnalog In (16 bits, ± 10 V A\/D), Zero dRI, Purge,\nRecycle In, Autoinject In, Alarm In\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eOutputs\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eAutoinject Retransmit, Alarm Out, Recycle Out (to switch Orbit between waste and recycle)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDimensions\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e58 cm (L) x 36 cm (W) x 18 cm (H)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e","brand":"Wyatt Technology","offers":[{"title":"Standard","offer_id":46488398528591,"sku":"WOP1U","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"658nm","offer_id":46488398561359,"sku":"WOP1U-65","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/microOptilab-Hero-Neon-10-2-19_8df3145a-587e-4105-9a61-39b2759e8c49.jpg?v=1787675377"},{"product_id":"wyatt-eclipse-field-flow-fractionation-system","title":"Eclipse Field-Flow Fractionation System","description":"\u003cspan\u003e\u003cp align=\"center\"\u003e\u003cimg alt=\"Eclipse DualTec\" class=\"scale-with-grid\" fetchpriority=\"high\" src=\"https:\/\/www.wyatt.com\/wp-content\/uploads\/2020\/10\/Eclipse-Hero.jpg\" width=\"700\"\u003e\u003c\/p\u003e\u003c\/span\u003e\n\u003cp\u003eThe ultimate separation system for nanoparticles and macromolecules\u003c\/p\u003e\n\u003cp\u003eUniquely Versatile\u003c\/p\u003e\n\u003cp\u003eField-flow fractionation is a uniquely versatile means of size-based separations, capable of fractionating viral particles, liposomes and lipid nanoparticles, emulsions, proteins and aggregates, polysaccharides and technical polymers, engineered nanoparticles, colloidal soil suspensions, chemical mechanical polishing slurries, and many more - with no stationary phase and almost no shear. Separation of biotherapeutics can usually be done in full formulation buffer.\u003c\/p\u003e\n\u003cp\u003eThe Eclipse system is the foundation of FFF-MALS, a powerful technique for separation and comprehensive characterization of macromolecules and nanoparticles from 1 to 1000 nm in size. Eclipse brings FFF to a completely new level, combining exquisite performance and ease of use. Advanced features include the Dilution Control Module (DCM) and the ability to switch seamlessly between FFF and size-exclusion chromatography (SEC) separations. The Mobility add-on system expands Eclipse’s capabilities to include measurements of charge and zeta potential.\u003c\/p\u003e\n\u003chr class=\"no_line\" style=\"margin: 0 auto 0px auto\"\u003e\n\n\u003cdiv class=\"column one-second\" style=\"padding-right:10px\"\u003e\n\u003cp style=\"color:#075c97;\"\u003eSimplicity and quality, with built-in intelligence\u003c\/p\u003e\n\u003cp\u003eThe Eclipse FFF system combines several modules that are integrated seamlessly in VISION\u003csup\u003e™\u003c\/sup\u003e software:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eThe Eclipse FFF flow instrument\u003c\/li\u003e\n\u003cli\u003eWaters\u003csup\u003e™\u003c\/sup\u003e\n Arc\u003csup\u003e™\u003c\/sup\u003e HPLC pump and autosampler\u003c\/li\u003e\n\u003cli\u003eIndustry standard pump and autosampler (legacy only)\u003c\/li\u003e\n\u003cli\u003eEclipse FFF channel\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThese modules may be added:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eIndustry standard fraction collector\u003c\/li\u003e\n\u003cli\u003eMobility EAF4 system\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"column one-second\" style=\"padding-right:10px\"\u003e\n\u003cdiv style=\"padding:0px 30px 0px 30px\"\u003e\n\u003cp align=\"center\" style=\"padding-top:80px\"\u003e \u003cimg alt=\"fff-mals\" src=\"https:\/\/www.wyatt.com\/wp-content\/uploads\/2024\/04\/WAT-Arc-HPLC-Optilab-DAWN-Eclipse-1000.jpg\" width=\"80%\"\u003e \u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003chr class=\"no_line\" style=\"margin: 0 auto 0px auto\"\u003e\n\u003cdiv class=\"column one-second mobile-one\"\u003e\u003cdiv class=\"mcb-column-inner\"\u003e\n\u003cp\u003eEclipse instrument\u003c\/p\u003e\n\u003cp\u003eThe Eclipse FFF instrument is the heart of the FFF system. It incorporates four highly precise and stable flow controllers that ensure robust and repeatable fractionation runs, without the associated pulsation and inherent complexity and low reliability of the multiple pumps found in other FFF systems. \u003c\/p\u003e\n\u003cp\u003eEclipse supports both tip injection and focus-zone injection, enabling use of a variety of FFF separation channels and even a size-exclusion chromatography column.\u003c\/p\u003e\n\u003cp\u003e\u003ci\u003eOptional features:\u003c\/i\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eFFF-SEC switching\u003c\/li\u003e\n\u003cli\u003eDilution Control Module (DCM)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e(see Options tab for more information)\u003c\/p\u003e\n\u003cp\u003eThe user interface is based on a 10” multi-touch display that lets users track progress of the method, know about events or conditions that need attention, and perform any necessary manual operations such as flushing the channel. Built-in intelligence provides health indicators and guided user assistance as well as self-diagnostics procedure.\u003c\/p\u003e\n\u003cp\u003eFront end\u003c\/p\u003e\n\u003cp\u003eThe front end for an Eclipse FFF system comprises a Waters and other industry-standard pumps and autosampler. These components are recognized by analytical laboratories as state-of-the-art for reliability and performance:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eLow pump ripple and pulsation\u003c\/li\u003e\n\u003cli\u003eNo wasted sample (no need to overfill the autosampler – 100 µL are loaded for a 100 µL injection)\u003c\/li\u003e\n\u003cli\u003eUsed in tens of thousands of laboratories around the world, including in the demanding bio\/pharmaceutical industry.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\u003c\/div\u003e\n\u003cdiv class=\"column one-second mobile-one\"\u003e\u003cdiv class=\"mcb-column-inner\"\u003e\n\u003cdiv style=\"padding:0px 30px 0px 30px\"\u003e\n\u003cp align=\"center\" style=\"padding-top:30px\"\u003e \u003cimg alt=\"fff-mals\" src=\"https:\/\/www.wyatt.com\/wp-content\/uploads\/2020\/10\/Eclipse-Hero.jpg\" width=\"80%\"\u003e \u003c\/p\u003e\n\u003cp align=\"center\"\u003e \u003cimg alt=\"fff-mals\" src=\"https:\/\/www.wyatt.com\/wp-content\/uploads\/2020\/10\/side-view-eclipse.jpg\" width=\"90%\"\u003e \u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\u003c\/div\u003e\n\u003chr class=\"no_line\" style=\"margin: 0 auto 0px auto\"\u003e\n\u003cdiv class=\"column one-second mobile-one\"\u003e\u003cdiv class=\"mcb-column-inner\"\u003e\n\u003cp\u003eEclipse FFF channels\u003c\/p\u003e\n\u003cp\u003eFractionation, which is what it’s all about, takes place in the open FFF channel which incorporates a semi-permeable (ultrafiltration) membrane supported by a frit. Eclipse channels offer several key advantages including extra-rigid construction, built-in temperature regulation and built-in dilution control ports. A variety of FFF channels are available to meet different needs – see the Channels tab to learn more.\u003c\/p\u003e\n\u003cp\u003eVISION™\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/www.wyatt.com\/products\/software\/vision.html\"\u003eVISION software\u003c\/a\u003e is the intelligent human interface to an FFF-MALS system built on Wyatt Technology’s Eclipse™ FFF and DAWN™ MALS instruments. It comprises two primary modules:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eVISION DESIGN™ for in silico method design and optimization\u003c\/li\u003e\n\u003cli\u003eVISION RUN™ for running FFF methods, with continuous system monitoring and self-diagnostics to ensure no wasted runs, lost sample or empty solvent bottle.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eVISION interfaces with ASTRA™ software to coordinate synchronization and real-time display of light scattering data within VISION. Both software packages have been developed under a formal quality system and are available in 21 CFR Part 11 compliant options that fulfill GMP and GLP requirements.\u003c\/p\u003e\n\u003c\/div\u003e\u003c\/div\u003e\n\u003cdiv class=\"column one-second mobile-one\"\u003e\u003cdiv class=\"mcb-column-inner\"\u003e\n\u003cdiv style=\"padding:0px 30px 0px 30px\"\u003e\n\u003cp align=\"center\" style=\"padding-top:30px\"\u003e \u003cimg alt=\"fff-mals\" src=\"https:\/\/www.wyatt.com\/wp-content\/uploads\/2021\/12\/Long-Channel-Exploded-12-21.jpg\" width=\"80%\"\u003e \u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\u003c\/div\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eEclipse\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eCompatible with aqueous and organic solvents. Corrosion-resistant from pH 2 to 12. Wetted materials: 316 stainless steel, FFKM perfluoroelastomer, FR3 stainless steel, Vespel. Cross-flow regulation from 6.67 to 0.03 mL\/min.\nPrecision of detector flow rate: 0.1% (with DCM). Dedicated fraction collector output port for minimal peak broadening.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eCommunications\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eEthernet\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eInputs\/Outputs\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eAlarm Out, Aux In with 18-bit effective resolution\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSoftware\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eVISION software suite. Comprises VISION DESIGN module for in silico method development and optimization, and VISION RUN for running sequences and coordinating ASTRA data acquisition.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eFFF-MALS Solution\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eBasic FFF-MALS system includes Eclipse instrument, one separation channel (matched to customer application), Waters and other industry-standard pump and autosampler, DAWN MALS instrument, VISION software suite and ASTRA light scattering analysis software.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDilution Control Module\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eFactory-installed option. Increases sample concentration at the detector by up to a factor of 10 (up to 5 with negligible loss of resolution), controlled by software.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSEC Switching Option\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eFactory-installed option. Allows for automated software-controlled switching between SEC mode and FFF mode.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMobility\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eAdd-on option. Includes Mobility Module with pH sensor and conductivity sensor with software supported calibration, and Mobility channel. Maximum operating voltage ± 30 V, maximum current 30 mA; constant current or constant voltage mode. Wetted materials: platinum, titanium, polyetherimide, alumina ceramic, PTFE, Viton, PEEK, polycarbonate.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDetectors and Modules\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003ePDA, UV\/Vis, FLD, fraction collector, etc.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDLS\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eWyattQELS™ embedded dynamic light scattering module\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSelection\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eShort, Long, Dispersion Inlet and Semi-Prep Channels available. Channel types are offered as fixed-height channel (without spacer) and variable-height channel (with spacer) options. All channels are compatible with aqueous and organic solvents and come with DCM port. Maximum pressure 30 bar.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eTemperature Regulation\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eAmbient to 50 °C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eWetted Materials\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e316 stainless steel, fused silica, FFKM perfluoroelastomer, alumina ceramic. Polycarbonate or Mylar according to the selected spacer for variable-height channels.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSpacers\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eSelection ranges from 250 μm to 1000 μm, depending on channel. FFKM perfluoroelastomer-coated polycarbonate for aqueous solvents, Mylar for organic solvents.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMembranes\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003ePre-cut polyethersulfone or regenerated cellulose with molecular-weight cutoff from 2 to 30 kDa. Templates available to cut other materials to size.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDimensions\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e58 cm (L) x 36 cm (W) x 26 cm (H) (Eclipse instrument)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\u003cp\u003e\u003ca href=\"https:\/\/www.wyatt.com\/products\/eclipse-brochure-request.html\" target=\"_blank\"\u003eBrochure\u003c\/a\u003e\u003c\/p\u003e","brand":"Wyatt Technology","offers":[{"title":"Standard","offer_id":46488398364751,"sku":"WEC","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"with Dilution Control Module","offer_id":46488398397519,"sku":"WECD","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"with Dilution Module \u0026 HP Switch","offer_id":46488398430287,"sku":"WECDSH","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/Eclipse-Hero.jpg?v=1787675377"},{"product_id":"wyatt-optilab-refractive-index-detector","title":"Optilab Refractive Index Detector","description":"\u003cspan\u003e\u003cp align=\"center\"\u003e\u003cimg alt=\"Optilab, refractometer\" class=\"scale-with-grid\" src=\"https:\/\/www.wyatt.com\/wp-content\/uploads\/2019\/10\/Optilab-Hero-Neon9-20-19.jpg\" width=\"65%\"\u003e\u003c\/p\u003e\u003c\/span\u003e\n\u003cp\u003eUniversal Detection for Chromatography and FFF Separations\u003c\/p\u003e\n\u003cp\u003eIndependent of Chromaphores\u003c\/p\u003e\n\u003cp\u003eIndependent of chromaphores or fluorophores, differential Refractive Index (dRI) detectors serve as accurate and versatile concentration detectors in all types of solvents. dRI is part of standard instrumentation for a variety of macromolecular characterization techniques including standard chromatography, SEC-MALS, FFF-MALS and CG-MALS.\u003c\/p\u003e\n\u003chr class=\"no_line\" style=\"margin: 0 auto 10px auto\"\u003e\n\u003cp\u003eUnique dRI Detector\u003c\/p\u003e\n\u003cp\u003eThe Optilab is a unique dRI detector for standard HPLC\/GPC with 256 times the detection power and 50 times the dynamic range of \u003ci\u003eevery other \u003c\/i\u003eRI detector for chromatography in existence today, making it a valuable addition to any MALS setup.\u003c\/p\u003e\n\u003cp\u003eUsing a combination of cutting-edge semiconductor photodiode technology and proprietary computer algorithms, the Optilab achieves an unprecedented combination of sensitivity and range. These features mean that it addresses both standard chromatographic applications and some challenges unique to light scattering measurements such as high concentrations, determination of sample refractive increments (\u003ci\u003edn\/dc\u003c\/i\u003e) and solvent refractive index.\u003c\/p\u003e\n\u003cp\u003eKey Benefits\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eExtraordinary dRI measurement range, -0.0047 to +0.0047 RIU (comparable to 25 mg\/mL protein in PBS)\u003c\/li\u003e\n\u003cli\u003eHighly sensitive, ±7.5 x 10\u003csup\u003e-10\u003c\/sup\u003e RIU across the \u003ci\u003eentire\u003c\/i\u003e measurement range\u003c\/li\u003e\n\u003cli\u003eMeasures solvent absolute refractive index, required for MALS calculations\u003c\/li\u003e\n\u003cli\u003eMeasures at the same wavelength as the MALS detector, for maximum accuracy in MALS calculations\u003c\/li\u003e\n\u003cli\u003eBand broadening \u0026lt; 20 µL preserves SEC resolution\u003c\/li\u003e\n\u003cli\u003eTemperature range 4 °C to 65 °C for proteins and polymers that require a range of temperatures\u003c\/li\u003e\n\u003cli\u003eHigh-resolution, touch-screen front panel displays data graphs and diagnostics, even with the host computer turned off\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eUnparalleled Features\u003c\/p\u003e\n\u003cp\u003eEven though the Optilab offers a dRI measurement range orders of magnitude beyond that of other dRI detectors, unlike other detectors there are no range or gain settings in the Optilab. The \u003ci\u003efull\u003c\/i\u003e range of instrument detection is \u003ci\u003ealways\u003c\/i\u003e present, and the full sensitivity exists over the \u003ci\u003eentire\u003c\/i\u003e range.\u003c\/p\u003e\n\u003cp\u003eThe Optilab can also do something no other on-line refractive index detector can: it can measure the \u003ci\u003eabsolute\u003c\/i\u003e refractive index of a solution. In addition, it can measure the \u003ci\u003edn\/dc\u003c\/i\u003e of a solvent at the \u003ci\u003esame\u003c\/i\u003e wavelength of light as the light scattering instrument. And just to make sure it can't be matched, you can replace the light source in the Optilab for other wavelengths (e.g., 690, 633, 488, etc.) in just minutes!\u003c\/p\u003e\n\u003cp\u003eThe Optilab can go below ambient temperatures as easily as above ambient. No hassle temperature control can be programmed from 4 °C to 65 °C. Compatible with all HPLC systems.\u003c\/p\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eRange (RIU)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e-0.0047 to +0.0047\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003ePeak-to-peak noise (RIU)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e± 7.5 x 10\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eHigh Concentration Option Range (RIU)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e-0.0026 to +0.034\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eHigh Concentration Option Peak-to-peak noise (RIU)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e± 1.5 x 10 RIU\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eResponse Time\n(User Selectable)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e0.1 to 5 seconds\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eAbsolute Refractive Index Range (RIU)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e1.2 to 1.8\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSensitivity (RIU)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e± 0.002\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eBand Broadening\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u0026lt; 12 μL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eFill Volume (inlet tubing + flow cell)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e51.4 μL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eOutlet tubing (0.030\" ID)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e370 μL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eBack pressure created at inlet port (@ 0.5 mL\/min H2O, 20 °C)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u0026lt;22 psi (1.5 bar)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMaximum permissible back pressure allowed at outlet port\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e30 psi (2 bar)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eControl Range\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e4 °C to 65 °C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eRegulation\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e± 0.005 °C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eLight Source\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eOptilab: 660 nm; Optilab HC: 660 nm standard, factory option for 785 nm\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSafety Sensors\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eVapor and liquid (leak)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDigital Output\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e22+ bits @ 10 Hz\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eAnalog Output\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e± 10 V or ± 1 V output, 18 bits resolution\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eComputer Interface\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eEthernet\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eFront Panel Display\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e7\" (178 mm), high-resolution, multi-touch display for viewing\/setting signals, instrument settings and diagnostics\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eInputs\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eAnalog In (16 bits, ± 10 V A\/D), Zero dRI, Purge,\nRecycle In, Autoinject In, Alarm In\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eOutputs\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eAutoinject Retransmit, Alarm Out, Recycle Out (to switch Orbit between waste and recycle)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDimensions\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e58 cm (L) x 36 cm (W) x 18 cm (H)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\u003cp\u003e\u003ca href=\"https:\/\/www.wyatt.com\/products\/optilab-brochure-request.html\" target=\"_blank\"\u003eBrochure\u003c\/a\u003e\u003c\/p\u003e","brand":"Wyatt Technology","offers":[{"title":"Standard","offer_id":46488398626895,"sku":"WOP1","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"High-Concentration","offer_id":46488398659663,"sku":"WOP1H","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"658nm","offer_id":46488398692431,"sku":"WOP1-65","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"High Concentration, 658nm","offer_id":46488398725199,"sku":"WOP1H-65","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"High Concentration, 785nm","offer_id":46488398757967,"sku":"WOP1H-78","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/Optilab-Hero-Neon9-20-19_9309252a-3f5c-4b8b-b3f8-f78b86962b96.jpg?v=1787675382"},{"product_id":"wyatt-microviscostar-online-differential-viscometer","title":"microViscoStar Online Differential Viscometer","description":"\u003cspan\u003e\u003cp align=\"center\"\u003e\u003cimg alt=\"microViscoStar\" class=\"scale-with-grid\" src=\"https:\/\/www.wyatt.com\/wp-content\/uploads\/2019\/10\/microViscoStar-Hero-Neon-10-2-19.jpg\" title=\"microViscoStar-1500\" width=\"65%\"\u003e\u003c\/p\u003e\u003c\/span\u003e\n\u003cp\u003emicroViscoStar: Online differential viscometer for UHPLC.\u003c\/p\u003e\n\u003cp\u003eHighly Sensitive\u003c\/p\u003e\n\u003cp\u003eA highly sensitive, on-line differential viscometer used with \u003ca href=\"https:\/\/www.wyatt.com\/solutions\/techniques\/sec-iv-polymer-molar-mass-and-conformation.html\"\u003eSEC-MALS-IV\u003c\/a\u003e to determine the size and conformation of polymers, proteins and peptides separated by UHPLC.\u003c\/p\u003e\n\u003chr class=\"no_line\" style=\"margin: 0 auto 10px auto\"\u003e\n\u003cp\u003eMultiple Novel Technologies\u003c\/p\u003e\n\u003cp\u003eThe microViscoStar\u003csup\u003e™\u003c\/sup\u003e incorporates multiple novel technologies to provide the highest sensitivity, stability and solvent compatibility of any available viscometer for UHPLC. Its ease-of-use and serviceability make it the perfect companion for Wyatt's \u003ca href=\"https:\/\/www.wyatt.com\/products\/instruments\/microDawn-multi-angle-detector-uhplc-sec-mals.html\"\u003emicroDAWN\u003csup\u003e™\u003c\/sup\u003e\u003c\/a\u003e light scattering and \u003ca href=\"https:\/\/www.wyatt.com\/products\/instruments\/microOptilab-uhplc-refractometer-sec-mals.html\"\u003emicroOptilab\u003csup\u003e™\u003c\/sup\u003e\u003c\/a\u003e refractive index detectors for UHPLC.\u003c\/p\u003e\n\u003chr class=\"no_line\" style=\"margin: 0 auto 10px auto\"\u003e\n\u003cp\u003eAPC and UHPLC Applications\u003c\/p\u003e\n\u003cp\u003eView the webinar \u003ca href=\"https:\/\/www.wyatt.com\/library\/webinars\/development-of-a-new-online-micro-viscometer-for-apc-and-uhplc-applications.html\"\u003eDevelopment of a New Online Micro-Viscometer for APC and UHPLC Applications\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003eTo learn about the technological breakthroughs implemented in the microViscoStar, download \u003ca href=\"https:\/\/wyattfiles.s3.us-west-2.amazonaws.com\/literature\/white-papers\/WP9005-ViscoStar-Innovations-in-Online-Viscometry.pdf\" target=\"_blank\"\u003eViscoStar: Innovations in Online Viscometry for GPC\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003eAnother path to polymer and protein characterization: SEC-MALS-IV\u003c\/p\u003e\n\u003cp\u003eWhen coupled with UHPLC size-exclusion chromatography and a compatible concentration detector such as the \u003ca href=\"https:\/\/www.wyatt.com\/products\/instruments\/optilab-refractive-index-detector.html\"\u003eOptilab\u003csup\u003e™\u003c\/sup\u003e\u003c\/a\u003e, the microViscoStar derives the intrinsic viscosity (IV) of polymers, rapidly and with minimal sample and solvent consumption. An inherently valuable physico-chemical property in itself, IV is best utilized together with molar mass information from a microDAWN multi-angle light scattering (SEC-MALS-IV) to  derive the \u003ci\u003ehydrodynamic radius\u003c\/i\u003e, \u003ci\u003econformation\u003c\/i\u003e, and \u003ci\u003ebranching ratio\u003c\/i\u003e of a macromolecule in solution.\u003c\/p\u003e\n\u003cdiv class=\"column one-second\"\u003e\n\u003cp\u003eKey benefits of the microViscoStar\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cb\u003eHigh sensitivity\u003c\/b\u003e, equivalent to 5 ng of 100 kDa polystyrene in THF at 1.0 mL\/min injected onto a standard GPC column\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eHigh dynamic range\u003c\/b\u003e of over 135,000:1. The full measurement range corresponds to over 13 mg\/mL of 100 kDa polystyrene in THF\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eExtended solvent compatibility\u003c\/b\u003e with all-316 stainless steel transducers\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eTemperature range\u003c\/b\u003e from 4 °C to 70 °C for polymers or proteins that require a range of temperatures\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eMinimal band broadening\u003c\/b\u003e thanks to fast pressure transducers\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003ePump pulse suppression\u003c\/b\u003e to below 4 Pa (hardware alone) or 1 Pa (hardware + software) without loss of chromatographic resolution \u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eAutomated capillary bridge tuning\u003c\/b\u003e with no moving parts, to guarantee a perfectly balanced bridge, every run\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eEnhanced thermal stability\u003c\/b\u003e with drift of \u0026lt;1.25 Pa\/hour\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cbr\u003e \n\u003cp\u003eSEC-IV without MALS?\u003c\/p\u003e\n\u003cp\u003eYes, as much as we love MALS for optimal polymer analysis, it's true that there are occasions when it just won't fit the bill.\u003c\/p\u003e\n\u003cp\u003e\u003ci\u003eUniversal calibration\u003c\/i\u003e is a parallel technique to SEC-MALS for determining molecular weight, commonly used to characterize linear polymers. While universal calibration overcomes some of the problematic issues  associated with column calibration by reference molecules, it does not account for non-ideal column behavior caused by chemical solute-column interactions or hyperbranching. \u003c\/p\u003e\n\u003cp\u003eUniversal calibration is particularly-well suited to replace MALS for:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cb\u003eStrongly fluorescent polymers\u003c\/b\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eWeakly-scattering\u003c\/b\u003e polymer\/solvent systems with very low \u003ci\u003edn\/dc\u003c\/i\u003e values\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003ci\u003eThe Mark-Houwink-Sakurada relationship\u003c\/i\u003e makes use of empirical relationships between intrinsic viscosity and molar mass, specific to each polymer and solvent, to estimate molar mass from SEC-IV measurements. Of course, the best way to determine MHS coefficients is to measure them using SEC-MALS-IV and ASTRA!\u003c\/p\u003e\n\u003cp\u003eGo to the \u003cb\u003eAdvanced Technology\u003c\/b\u003e tab to learn more about the unique features of the microViscoStar.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"column one-second\"\u003e\n\u003cp align=\"center\"\u003e\u003cimg alt=\"microViscostar pump pulse  suppression\" src=\"https:\/\/www.wyatt.com\/wp-content\/uploads\/2019\/05\/pump-pulse-suppression-with-inset.jpg\" title=\"microViscostar pump pulse suppression\"\u003e\u003c\/p\u003e\n\u003cp align=\"left\" style=\"color:#075c97;font-size:14px;padding-left:30px\"\u003ePatented pulse compensation technology in the microViscoStar eliminates pump fluctuations. At the hardware level, the bridge is impedance-matched for dynamic balance, greatly reducing the effect of pump pulses. An additional layer of software filtering eliminates residual pump pulses.\u003c\/p\u003e\n\u003cfigure style=\"margin-left: 15px; text-align: center;\"\u003e\u003cimg alt=\"microViscoStar measurements of epoxy resins\" src=\"https:\/\/www.wyatt.com\/wp-content\/uploads\/2019\/05\/mVS-epoxy.png\" title=\"microViscoStar measurements of \n        epoxy resins\"\u003e\n\u003cp align=\"left\" style=\"color:#075c97;font-size:14px;padding-left:30px\"\u003eThe microVisoStar maintains the narrow peaks and excellent resolution of UHPLC with maximum sensitivity. In this graph, the refractive index and specific viscosity chromatograms of an epoxy resin are overlaid with the molar mass and intrinsic viscosity results calculated from MALS and specific viscosity data, respectively, at each elution volume. The sample was separated on four Waters\u003csup\u003e®\u003c\/sup\u003e APC XT columns in series with pore sizes of 45, 125, 450 and 900 Å.\u003c\/p\u003e\u003c\/figure\u003e\n\u003c\/div\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSensitivity (minimum detectable sample)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e5 ng of 100 kDa polystyrene in THF at 1 mL\/min, under typical UHPLC-SEC conditions\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDifferential pressure noise\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u0026lt; 0.05 Pa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDifferential pressure range\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e6.9 kPa, protected against overpressure\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDynamic range\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e135,000:1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eLinearity\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e0.5% of full scale\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDifferential pressure drift\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u0026lt; 1.25 Pa\/hr\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eCapillary bridge autobalance\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eThermal, leak-free mechanism\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSample shear rate\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e15000 Hz with water at 1 mL\/min\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMax. flow rate\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eAqueous: 1 mL\/min; THF: 1 mL\/min\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDelay volume options\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e5.4 mL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMax. permissible pressure inlet to outlet\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e3000 kPa (435 psi)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eWetted Materials\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e316 stainless steel, PTFE, zirconium silicate, Kalrez , Inconel, 26-1 Stainless Steel, Nickel\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eRange\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e4 °C to 70 °C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eStability\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u0026lt;0.005°C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eAmbient Range\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e0 ºC to 40 ºC, 20% to 70% RH\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDigital Output\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e20 bits @ 10 Hz\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eInputs\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eAutoinject contact closure, Alarm In, Analog In: 2 differential inputs, 16 bits resolution, range -10 V to +10 V\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eOutputs\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eAutoinject Retransmit, Alarm Out, Recycle Out\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eCommunications\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eEthernet\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eFront Panel Display\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e7\" (178 mm), high-resolution, multi-touch display for viewing\/setting signals, instrument settings and diagnostics.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDimensions\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e60 cm (L) x 36 cm (W) x 17 cm (H)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\u003cp\u003e\u003ca href=\"https:\/\/www.wyatt.com\/products\/microviscostar-brochure-request.html\" target=\"_blank\"\u003eBrochure\u003c\/a\u003e\u003c\/p\u003e","brand":"Wyatt Technology","offers":[{"title":"Standard","offer_id":46488398823503,"sku":"WUV4","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Standard Delay Column","offer_id":46488398856271,"sku":"WUV4-01","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/microViscoStar-Hero-Neon-10-2-19_aca2bc34-e001-4882-ae70-6f70937771f3.jpg?v=1787675383"},{"product_id":"wyatt-viscostar-online-differential-viscometer","title":"ViscoStar Online Differential Viscometer","description":"\u003cspan\u003e\u003cp align=\"center\"\u003e\u003cimg alt=\"ViscoStar III\" class=\"scale-with-grid\" src=\"https:\/\/www.wyatt.com\/wp-content\/uploads\/2019\/10\/ViscoStar-Hero-Bright-Screen-9-19.jpg\" title=\"ViscoStar-Hero-Neon-800\" width=\"65%\"\u003e\u003c\/p\u003e\u003c\/span\u003e\n\u003cp\u003eViscoStar: The next generation online differential viscometer.\u003c\/p\u003e\n\u003cp\u003eHighly Sensitive\u003c\/p\u003e\n\u003cp\u003eA highly sensitive, on-line differential viscometer used in conjunction with \u003ca href=\"https:\/\/www.wyatt.com\/solutions\/techniques\/sec-iv-polymer-molar-mass-and-conformation.html\"\u003eSEC-MALS-IV\u003c\/a\u003e to determine the size and conformation of all types of biopolymers, synthetic polymers and even proteins and peptides.\u003c\/p\u003e\n\u003chr class=\"no_line\" style=\"margin: 0 auto 10px auto\"\u003e\n\u003cp\u003eMultiple Novel Technologies\u003c\/p\u003e\n\u003cp\u003eThe ViscoStar incorporates multiple novel technologies to provide the highest sensitivity, stability and solvent compatibility of any available viscometer for GPC. Its ease-of-use and serviceability make it the perfect companion for Wyatt's \u003ca href=\"https:\/\/www.wyatt.com\/products\/instruments\/dawn-multi-angle-light-scattering-detector.html\"\u003eDAWN\u003csup\u003e™\u003c\/sup\u003e\u003c\/a\u003e light scattering and \u003ca href=\"https:\/\/www.wyatt.com\/products\/instruments\/optilab-refractive-index-detector.html\"\u003eOptilab\u003csup\u003e™\u003c\/sup\u003e\u003c\/a\u003e refractive index detectors.\u003c\/p\u003e\n\u003chr class=\"no_line\" style=\"margin: 0 auto 10px auto\"\u003e\n\u003cp\u003eWhite Paper\u003c\/p\u003e\n\u003cp\u003eDownload \"\u003ca href=\"https:\/\/wyattfiles.s3.us-west-2.amazonaws.com\/literature\/white-papers\/WP9005-ViscoStar-Innovations-in-Online-Viscometry.pdf\" target=\"_blank\"\u003eViscoStar: Innovations in Online Viscometry for GPC\u003c\/a\u003e\".\u003c\/p\u003e \n\u003cp\u003eAnother path to polymer and protein characterization: SEC-MALS-IV\u003c\/p\u003e\n\u003cp\u003eWhen coupled with size-exclusion chromatography and a concentration detector such as the Optilab\u003csup\u003e™\u003c\/sup\u003e, the ViscoStar derives the intrinsic viscosity (IV) of polymers. An inherently valuable physico-chemical property in itself, IV is best utilized together with molar mass information from multi-angle light scattering (SEC-MALS-IV) to derive the \u003ci\u003ehydrodynamic radius\u003c\/i\u003e, \u003ci\u003econformation\u003c\/i\u003e, and \u003ci\u003ebranching ratio\u003c\/i\u003e of a macromolecule in solution.\u003c\/p\u003e\n\u003cdiv class=\"column one-second\"\u003e\n\u003cp\u003eKey benefits of the ViscoStar\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cb\u003eHigh sensitivity\u003c\/b\u003e, equivalent to 100 ng of 100 kDa polystyrene in THF at 1.0 mL\/min injected onto a standard GPC column\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eHigh dynamic range\u003c\/b\u003e of over 135,000:1. The full measurement range corresponds to over 13 mg\/mL of 100 kDa polystyrene in THF\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eExtended solvent compatibility\u003c\/b\u003e with all-316 stainless steel transducers\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eTemperature range\u003c\/b\u003e from 4 °C to 70 °C for polymers or proteins that require a range of temperatures\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eMinimal band broadening\u003c\/b\u003e thanks to fast pressure transducers\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003ePump pulse suppression\u003c\/b\u003e to below 4 Pa (hardware alone) or 1 Pa (hardware + software) without \n              loss of chromatographic resolution \n  \t\t\t\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eAutomated capillary bridge tuning\u003c\/b\u003e with no moving parts, to guarantee a perfectly balanced bridge, every run\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eEnhanced thermal stability\u003c\/b\u003e with drift of \u0026lt;2.5 Pa\/hour\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eSEC-IV without MALS?\u003c\/p\u003e\n\u003cp\u003eYes, as much as we love MALS for optimal polymer analysis, it's true that there are occasions when it just won't fit the bill.\u003c\/p\u003e\n\u003cp\u003e\u003ci\u003eUniversal calibration\u003c\/i\u003e is a parallel technique to SEC-MALS for determining molecular weight, commonly used to characterize linear polymers. While universal calibration overcomes some of the problematic issues associated with column calibration by reference molecules, it does not account for non-ideal column behavior caused by chemical solute-column interactions or hyperbranching.\u003c\/p\u003e\n\u003cp\u003eUniversal calibration is particularly-well suited to replace MALS for:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cb\u003eStrongly fluorescent polymers\u003c\/b\u003e, in particular those not adequately addressed by a \n      \u003ca href=\"https:\/\/www.wyatt.com\/products\/instruments\/dawn-multi-angle-light-scattering-detector.html\"\u003eDAWN™\u003c\/a\u003e with long-wavelength (785 nm) laser or a standard DAWN (685 nm) with fluorescence-blocking filters.\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eWeakly-scattering\u003c\/b\u003e polymer\/solvent systems with very low \u003ci\u003edn\/dc\u003c\/i\u003e values\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003ci\u003eThe Mark-Houwink-Sakurada relationship\u003c\/i\u003e makes use of empirical relationships between intrinsic viscosity and molar mass, specific to each polymer and solvent, to estimate molar mass from SEC-IV measurements. Of course, the best way to determine MHS coefficients is to measure them using SEC-MALS-IV and ASTRA\u003csup\u003e™\u003c\/sup\u003e!\u003c\/p\u003e\n\u003cp\u003eGo to the \u003ca href=\"https:\/\/www.wyatt.com\/products\/instruments\/viscostar-online-differential-viscometer.html#viscostar-3\"\u003e\u003cb\u003eAdvanced Technology\u003c\/b\u003e\u003c\/a\u003e tab to learn more about the unique features of the ViscoStar.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"column one-second\"\u003e\n\u003cfigure style=\"margin-left: 15px; text-align: center;\"\u003e\u003cimg alt=\"Viscostar pump pulse \n        suppression\" src=\"https:\/\/www.wyatt.com\/wp-content\/uploads\/2019\/05\/pump-pulse-suppression-with-inset.jpg\" title=\"Viscostar pump pulse suppression\"\u003e\n\u003cp align=\"left\" style=\"color:#075c97;font-size:14px;padding-left:30px\"\u003ePatented pulse compensation technology in the ViscoStar eliminates pump fluctuations. At the hardware level, the bridge is impedance matched for dynamic balance, greatly reducing the effect of pump pulses. An additional layer of software filtering eliminates residual pump pulses.\u003c\/p\u003e\n\u003c\/figure\u003e\n\u003cfigure style=\"margin-left: 15px; text-align: center;\"\u003e\u003cimg alt=\"ViscoStar measurements of PLGA and carboxymethyl cellulose\" src=\"https:\/\/www.wyatt.com\/wp-content\/uploads\/2019\/05\/cmc-plga-intrinsic-viscosity-graphs.jpg\" title=\"ViscoStar measurements of PLGA and carboxymethyl cellulose\"\u003e\n\u003cp align=\"left\" style=\"color:#075c97;font-size:14px;padding-left:30px\"\u003eThe ViscoStar provides the highest available dynamic range and sensitivity in online viscometry. This graph shows the intrinsic viscosities of 1) poly(lactic co-glycolic acid), or PLGA, in THF and 2) carboxymethyl cellulose, or CMC, in aqueous mobile phase, both measured with a ViscoStar and Optilab, spanning a range from tens to thousands of mL\/g. The same instruments readily measure intrinsic viscosity values in the      low single digits with excellent signal-to-noise, even at very low concentrations.\n\t\t\u003c\/p\u003e\u003c\/figure\u003e\n\u003cfigure style=\"margin-left: 15px; text-align: center;\"\u003e\u003cimg alt=\"viscostar-measurement of protein size as hydrodynamic radius\" src=\"https:\/\/www.wyatt.com\/wp-content\/uploads\/2019\/05\/v3-protein-rh-measurements.jpg\" title=\"Viscometric analysis of protein size\"\u003e\n\u003cp align=\"left\" style=\"color:#075c97;font-size:14px;padding-left:30px\"\u003eThree IgG proteins with similar MWs eluted at different elution volumes. To understand their different elution properties, online DLS is typically used to measure the hydrodynamic radius, \u003ci\u003eR\u003c\/i\u003e\u003csub\u003eh\u003c\/sub\u003e, of a protein. However, online DLS did not provide reliable insights, in this case due to the relatively high experimental uncertainty of the DLS. The precise Rh values obtained with a MALS detector and the ViscoStar III, on the other hand, clearly revealed the causes. IgG B eluted later than IgG A due to its more compact structure; IgG C had a slight interaction with the SEC column.\u003c\/p\u003e\u003c\/figure\u003e\n\u003c\/div\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSensitivity (minimum detectable sample)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e0.1 μg of 100 kDa polystyrene in THF at 1 mL\/min, under typical GPC conditions\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDifferential pressure noise\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u0026lt; 0.05 Pa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDifferential pressure range\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e6.9 kPa, protected against overpressure\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDynamic range\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e135,000:1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eLinearity\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e0.5% of full scale\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDifferential pressure drift\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u0026lt; 2.5 Pa\/hr\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eCapillary bridge autobalance\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eThermal, leak-free mechanism\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSample shear rate\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e5000 Hz with water at 1 mL\/min\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMax. flow rate\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eAqueous: 1.5 mL\/min; THF: 3 mL\/min\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDelay volume options\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e16.2, 10.8 or 5.4 mL, with additional factory-installed option for 32.4 mL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMax. permissible pressure inlet to outlet\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e690 kPa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eWetted Materials\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e316 stainless steel, PTFE, zirconium silicate, Kalrez, Inconel, 26-1 Stainless Steel\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eRange\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e4 ºC to 70 ºC\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eStability\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u0026lt;0.005°C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eAmbient Range\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e0 ºC to 40 ºC, 20% to 70% RH\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDigital Output\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e20 bits @ 10 Hz\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eInputs\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eAutoinject contact closure, Alarm In, Analog In: 2 differential inputs, 18 bits resolution, range -10 V to +10 V\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eOutputs\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eAutoinject Retransmit, Alarm Out, Recycle Out\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eCommunications\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eEthernet\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eFront Panel Display\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e7\" (178 mm), high-resolution, multi-touch display for viewing\/setting signals, instrument settings and diagnostics.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDimensions\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e58 cm (L) x 36 cm (W) x 18 cm (H)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\u003cp\u003e\u003ca href=\"https:\/\/www.wyatt.com\/products\/viscostar-brochure-request.html\" target=\"_blank\"\u003eBrochure\u003c\/a\u003e\u003c\/p\u003e","brand":"Wyatt Technology","offers":[{"title":"Standard","offer_id":46488398954575,"sku":"WV4","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Standard Delay Column","offer_id":46488398987343,"sku":"WV4-01","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/ViscoStar-Hero-Bright-Screen-9-19.jpg?v=1787675386"},{"product_id":"wyatt-calypso-ii-composition-gradient-system","title":"Calypso II Composition-Gradient System","description":"\u003cspan\u003e\u003cp align=\"center\"\u003e\u003cimg alt=\"Calypso II\" class=\"scale-with-grid\" src=\"https:\/\/www.wyatt.com\/wp-content\/uploads\/2019\/05\/Calypso.jpg\" title=\"Calypso\" width=\"65%\"\u003e\u003c\/p\u003e\u003c\/span\u003e\n\u003cp\u003eLabel-free, immobilization-free characterization of protein-protein and other macromolecular interactions with composition-gradient multi-angle light scattering.\u003c\/p\u003e\n\u003cp\u003eCG-MALS\u003c\/p\u003e\n\u003cp\u003eThe Calypso II, in conjunction with a \u003ca href=\"https:\/\/www.wyatt.com\/products\/instruments\/dawn-multi-angle-light-scattering-detector.html\"\u003eDAWN\u003csup\u003e™\u003c\/sup\u003e\u003c\/a\u003e or \u003ca href=\"https:\/\/www.wyatt.com\/products\/instruments\/minidawn-multi-angle-light-scattering-detector-sec-mals.html\"\u003eminiDAWN\u003csup\u003e™\u003c\/sup\u003e\u003c\/a\u003e MALS detector, measures binding affinities and absolute, molecular stoichiometries of complex biomolecular interactions.\u003c\/p\u003e\n\u003chr class=\"no_line\" style=\"margin: 0 auto 10px auto\"\u003e\n\u003cp\u003eWeight-Average Molar Mass\u003c\/p\u003e\n\u003cp\u003eIn addition to equilibrium association constants \u003ci\u003eK\u003c\/i\u003e\u003csub\u003ed\u003c\/sub\u003e and absolute stoichiometry of reversible self- and hetero-associations, it can also help determine reaction or aggregation rates, non-specific interaction parameters (virial coefficients) and even automate measurements of weight-average molar mass and \u003ci\u003edn\/dc \u003c\/i\u003efor polymers.\u003c\/p\u003e\n\u003chr class=\"no_line\" style=\"margin: 0 auto 10px auto\"\u003e\n\u003cp\u003eCALYPSO\u003csup\u003e™\u003c\/sup\u003e Software\u003c\/p\u003e\n\u003cp\u003eIncluded with each Calypso is a copy of \u003ca href=\"https:\/\/www.wyatt.com\/products\/software\/calypso-software.html\"\u003eCALYPSO software\u003c\/a\u003e, the most versatile software package available for analysis of biomolecular interactions in solution by light scattering.\u003c\/p\u003e\n\u003cdiv class=\"column one-second\"\u003e\n\u003cp\u003eCreating composition gradients...\u003c\/p\u003e\n\u003cp\u003eCG-MALS employs a Calypso connected to a MALS instrument and optional concentration detector. The Calypso performs sample preparation and delivery, combining up to three different solution in precise mixing ratios and injecting into the detectors.\u003c\/p\u003e\n\u003cp\u003eAccurate compositions result from setting the Calypso's pumps to appropriate flow rate ratios, all controlled from the CALYPSO\u003csup\u003e™\u003c\/sup\u003e software through an intuitive GUI. Mixing is achieved by dispensing the solutions simultaneously from all three pumps via a static mixer.\u003c\/p\u003e\n\u003cp\u003e...that work with MALS detectors\u003c\/p\u003e\n\u003cp\u003eReliable light scattering measurement require the samples to be degassed and filtered. The Calypso incorporates built-in, low-volume degassers and filter housings, connected via PEEK tubing and finger-tight fittings. Even the filter housing is finger-tight, making use of a proprietary design for maximum convenience.\u003c\/p\u003e\n\u003cp\u003eCalypso features\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eBiocompatible wetted materials.\u003c\/li\u003e\n\u003cli\u003eFlexibility to re-organize fluid paths and utilize different wetted materials as needed.\u003c\/li\u003e\n\u003cli\u003eConvenient loading of sample and diluent solutions via conical tubes: 5, 15 or 50 mL.\u003c\/li\u003e\n\u003cli\u003eAutoinject Out contact closure signal, to trigger data acquisition by \u003ca href=\"https:\/\/www.wyatt.com\/products\/software\/astra.html\"\u003eASTRA\u003csup\u003e™\u003c\/sup\u003e\u003c\/a\u003e or \u003ca href=\"https:\/\/www.wyatt.com\/products\/software\/dynamics.html\"\u003eDYNAMICS\u003csup\u003e™\u003c\/sup\u003e\u003c\/a\u003e software for data acquisition and analyses not supported by the CALYPSO software (e.g., DLS acquisition).\u003c\/li\u003e\n\u003cli\u003eBuilt-in Wash port, allowing the pumps to draw on reservoirs of wash solutions for post-experimental clean-up. Automation of up to two sequential wash solutions, e.g. buffer (to clean out proteins) followed by water (to clean out buffer salts) or detergent followed by water, is possible when an \u003ca href=\"https:\/\/store.wyatt.com\/shop\/eclipse\/dualtec-o\/orbit\/\"\u003eOrbit\u003csup\u003e™\u003c\/sup\u003e solvent selector valve\u003c\/a\u003e is added to the setup. These operations are appended to the Method for unattended operation.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"column one-second\"\u003e\n\u003c!--[video_embed video=\"\" parameters=\"\" mp4=\"https:\/\/www.labtube.tv\/videos\/720p\/151907-720.mp4\" ogv=\"\" placeholder=\"\" width=\"400\" height=\"215\"]  \t\n\n          \u003cp\u003e\u003cb\u003ePlay video to learn more about the Calypso system\u003c\/b\u003e\u003c\/p\u003e\n  \t\t\u003cp\u003e\n           \n      \u003c\/p\u003e\t--\u003e\n\u003cimg align=\"right\" alt=\"Calypso Experimental Setup\" height=\"399px\" src=\"https:\/\/www.wyatt.com\/wp-content\/uploads\/2019\/05\/Calypso-DAWN-Optilab-Neon-System.jpg\" style=\"margin: 15px\" width=\"400px\"\u003e\n\u003c\/div\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSyringe Pumps\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e3 computer-controlled pumps; dc-servo motor, for minimum pulsation; 3-port distribution valve on each pump for Input, Output and Wash\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSyringe Volumes\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e12.5 µL to 2.5 mL (1 mL and 0.5 mL syringes supplied as standard)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDegasser Channels\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e1 per pump, 60 µL internal volume\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003ePressure Limit\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e1 mL syringes: 200 psi 0.5 mL syringes: 400 psi\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eAuxiliary Inputs\/Outputs\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eAutoinject out, injector valve control, recycle valve control, digital and analog I\/O for specific applications\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSolvents\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eAqueous\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eWetted Materials\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eBorosilicate glass, PEEK, PTFE, polyethylene, alumina, titanium, stainless steel\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eTypical Sample Volume Per Analysis\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e2.5 to 7 mL, depending on detector configuration and complexity of analysis\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eRange of Measurement\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eEquilibrium Dissociation Constant, K D : 100 pM to 1 mM typical for 100 kDa molecules (actual range varies with molecular weight and association stoichiometry)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eRepeatability of Measurement\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eM w : ± 5% A 2 : ± 0.5 x 10 mol·mL\/g² for sample molar mass of 50 to 100 kDa log( K D ): ± 0.3\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSpecific Binding\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eSee CALYPSO Software for more details. Self-association Hetero-association Multi-valent Combined self- and hetero-association incompetent (inactive) fraction Cooperativity and competitive binding Binding with thermodynamic non-ideality (high concentration) Concatenate multiple data sets for global fit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eNon-Specific Interactions\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eSelf-interaction: 2 and 3 virial coefficients Hetero-interactions: cross virial coefficients with 2 self-virial coefficients\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eKinetics\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e1 -order analyzed in software; export data for higher-order kinetics\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eAdditional analyses\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003edn\/dc\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eHost PC Requirements\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eUSB port for Calypso Ethernet connection for DAWN \/ miniDAWN communications\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDimensions\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e58 cm (L) x 37 cm (W) x 35 cm (H)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\u003cp\u003e\u003ca href=\"https:\/\/www.wyatt.com\/products\/calypso-brochure-request.html\" target=\"_blank\"\u003eBrochure\u003c\/a\u003e\u003c\/p\u003e","brand":"Wyatt Technology","offers":[{"title":"Default Title","offer_id":46488399020111,"sku":"WCG3","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/Calypso.jpg?v=1787675387"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/collections\/WAT_WYATT_gradient_logo.png?v=1787674450","url":"https:\/\/www.danyel.co.il\/collections\/wyatt-technology.oembed","provider":"danyel biotech","version":"1.0","type":"link"}