{"title":"QuantaMatrix","description":"\u003cp\u003eQuantaMatrix (Seoul, Korea) develops dRAST™, the direct and rapid antimicrobial susceptibility test that reports MIC-based results from positive blood cultures in as low as 4 hours, and the QMAC-dRAST Gram-negative and Gram-positive panel kits it runs.\u003c\/p\u003e","products":[{"product_id":"quantamatrix-drast-rapid-antimicrobial-susceptibility-testing-system-qmdrastr02","title":"dRAST Rapid Antimicrobial Susceptibility Testing System","description":"\u003cp\u003edRAST provides MIC-based phenotypic antimicrobial susceptibility testing direct from positive blood culture in as low as 4 hours; reducing time to results by up to 2 days compared to conventional method. The rapid results allow for earlier optimization of antibiotics in critically-ill patients with bloodstream infections and sepsis.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eDedicated to positive blood culture samples\u003c\/li\u003e\n\u003cli\u003eProvides phenotypic MIC in as low as 4 hours\u003c\/li\u003e\n\u003cli\u003eRandom access with up to 12 samples simultaneously (15 panel positions)\u003c\/li\u003e\n\u003cli\u003eExpert system on board with choice of guidelines\u003c\/li\u003e\n\u003cli\u003eEasy start with no McFarland required, no sample prep\u003c\/li\u003e\n\u003cli\u003e2 panels: 1 Gram Neg. + 1 Gram Pos.\u003c\/li\u003e\n\u003cli\u003eEasy to use, fast to operate\u003c\/li\u003e\n\u003cli\u003eNo daily maintenance\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003e2 days faster than conventional AST\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eConventional AST from blood can take at least three days or longer to produce results, as bacteria first has to be detected in blood and a pure isolate obtained before AST can proceed. dRAST, on the other hand, utilizes microfluidic technology and microscopic imaging technology that eliminates the need for pure isolate, to enable much faster results that can impact optimize antibiotic prescribing sooner.\u003c\/p\u003e\u003cp\u003e\u003cimg src=\"https:\/\/www.quantamatrix.com\/wp-content\/uploads\/2022\/07\/Capture-de%CC%81cran-2022-07-12-a%CC%80-15.15.17-1024x195.png\" alt=\"dRAST time to result compared with conventional AST\" style=\"max-width:100%;height:auto\" loading=\"lazy\"\u003e\u003c\/p\u003e\u003ch2\u003eWorkflow\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003eClinical workflow\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cimg src=\"https:\/\/www.quantamatrix.com\/wp-content\/uploads\/2022\/07\/drast_workflow_img2_en.jpeg\" alt=\"dRAST clinical workflow\" style=\"max-width:100%;height:auto\" loading=\"lazy\"\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eTechnical workflow\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cimg src=\"https:\/\/www.quantamatrix.com\/wp-content\/uploads\/2022\/07\/drast_workflow_img-1024x358.png\" alt=\"dRAST technical workflow\" style=\"max-width:100%;height:auto\" loading=\"lazy\"\u003e\u003c\/p\u003e\u003ch2\u003eSoftware\u003c\/h2\u003e\u003cp\u003eUser-friendly interface\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eSimple\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eTouchscreen user interface (UI)\u003c\/li\u003e\n\u003cli\u003eIntuitive result reporting\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003eLis\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eBi-directional LIS connectivity\u003c\/li\u003e\n\u003cli\u003eCompatible with all major LIS\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003eFlexible\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eRandom access and fully automated to improve workflow\u003c\/li\u003e\n\u003cli\u003eCustom expert rules to accommodate individual lab guidelines\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003eExpert System\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eIntegration with international and local guidelines (EUCAST, CLSI, and CA-SFM)\u003c\/li\u003e\n\u003cli\u003eReal-time display of raw data and interpreted results\u003c\/li\u003e\n\u003cli\u003eDisplay of MICs and SIR determination in a single screen\u003c\/li\u003e\n\u003cli\u003eActivated comments and rules for each sample, allowing the clinicians and infectious disease specialists to get all the relevant information\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eAntibiotic panels\u003c\/h2\u003e\u003cp\u003eGram-positive and Gram-negative panels using either CLSI or EUCAST recommended antimicrobials and breakpoints are available for dRAST.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eCLSI panel: 17 Gram-positive , 19 Gram-negative antibiotics with multiple concentrations\u003c\/li\u003e\n\u003cli\u003eEUCAST panel: 18 Gram-positive , 17 Gram-negative antibiotics with multiple concentrations\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eClinical evidence\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003edRAST provides susceptibility test results with greater reliability at enhanced speed.\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eAnalysis of susceptibility results generated by conventional testing methods took an average of 64.5 hours while results from dRAST direct from positive blood cultures only took 14.3 hours.\u003c\/p\u003e\u003cp\u003eSusceptibility result from dRAST is not only rapid but also reliable. Compared to Broth Micro-Dilution (BMD), the overall agreement for dRAST was 94.2% (49\/52) and 98.5% (66\/67) for patients with gram-positive and gram-negative bacteremia, respectively.\u003c\/p\u003e\u003cp\u003e\u003cem\u003eKim et al., Journal of Medical Microbiology 2018; 67: 325-331\u003c\/em\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eRapid AST is critical for timely prescribing of optimal, targeted antimicrobials.\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eA prospective study demonstrated the superior impact of dRAST on the selection of optimal antimicrobial therapy for resistant strains compared to Gram staining or MALDI-TOF MS identification.\u003c\/p\u003e\u003cp\u003eThe proportion of optimal targeted treatment was similar between the Gram-staining and the MALDI-TOF MS groups. However, there was significant improvement for the dRAST group compared to the MALDI-TOF MS group. The dRAST group demonstrated a 32% higher rate of optimal, targeted antimicrobial therapy compared to MALDI-TOF and the rate of ineffective therapy was 26% lower.\u003c\/p\u003e\u003cp\u003eThe study demonstrated that result of rapid AST using dRAST contributes significantly more than that of bacterial ID to the administration of optimal targeted antimicrobial treatment.\u003c\/p\u003e\u003cp\u003e\u003cem\u003eKim et al., Journal of Antimicrobial Chemotherapy, Volume 74, Issue 8, August 2019, Pages 2255–2260\u003c\/em\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eRapid AST by dRAST enables successful implementation of antimicrobial stewardship even in the treatment of bacteremia in the immunosuppressed patients.\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eRapid AST by dRAST enables successful implementation of antimicrobial stewardship even for immunosuppressed patients with bacteremia as well as those with underlying hematological disorders.\u003c\/p\u003e\u003cp\u003eDeploying dRAST into the diagnostic process allows more timely management of optimal, targeted treatment. In a recent study, time to initiation of optimal, targeted antimicrobials decreased by 14 hours in the dRAST group (39.0 hrs) compared to the conventional AST group (53.2 hrs).\u003c\/p\u003e\u003cp\u003eIn addition, the proportion of patients receiving optimal, targeted treatment at 48 hours from the first blood draw higher was higher in the dRAST group (66.1%) compared to the conventional AST group (48.3%). Also, the proportion of patients receiving broad-spectrum treatment at 48 hours was lower in the dRAST group (21.4%) compared to the conventional AST group (31.7%).\u003c\/p\u003e\u003cp\u003e\u003cem\u003eKim et al., Clin Microbiol Infect. Volume 27, Issue 1, 2021,Pages 69-75\u003c\/em\u003e\u003c\/p\u003e","brand":"QuantaMatrix","offers":[{"title":"Default Title","offer_id":67669176975439,"sku":"QMdRASTR02","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/drast_check_box_img_205fcba2-d23f-4dc5-ac71-c95bc4888175.jpg?v=1791735519"},{"product_id":"quantamatrix-qmac-drast-s17-clsi-antibiotic-panel-kit-10-tests-qmdrastn02","title":"QMAC-dRAST S17 CLSI Antibiotic Panel Kit for dRAST, 10 Tests","description":"\u003cp\u003eOur dRAST test kit consists of Panel, Agarose, and Broth. The kit runs on the dRAST system and delivers MIC-based phenotypic susceptibility results directly from positive blood culture in as low as 4 hours. Gram-positive and Gram-negative panels using either CLSI or EUCAST recommended antimicrobials and breakpoints are available for dRAST.\u003c\/p\u003e\u003ch2\u003eKit components\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eQMAC-dRAST Panel:\u003c\/strong\u003e 96-well plate with panel of dried-down antibiotics at various concentrations\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eQMAC-dRAST Agarose:\u003c\/strong\u003e Gel used for bacterial immobilization\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eQMAC-dRAST Broth:\u003c\/strong\u003e Pipette tips and broth dispensed to enable bacterial growth\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eAntibiotic panel\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eCLSI panel: 17 Gram-positive , 19 Gram-negative antibiotics with multiple concentrations\u003c\/li\u003e\n\u003cli\u003eEUCAST panel: 18 Gram-positive , 17 Gram-negative antibiotics with multiple concentrations\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003eCLSI panel, Gram negative (QMdRASTN02)\u003c\/strong\u003e\u003c\/p\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eAntibiotic\u003c\/th\u003e\n\u003cth\u003eEnterobacterales\u003c\/th\u003e\n\u003cth\u003ePseudomonas aeruginosa\u003c\/th\u003e\n\u003cth\u003eAcinetobacter spp.\u003c\/th\u003e\n\u003cth\u003eBurkholderia cepacia\u003c\/th\u003e\n\u003cth\u003eStenotrophomonas maltophilia\u003c\/th\u003e\n\u003cth\u003eOther non-Enterobacterales\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eAmikacin\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAmoxicillin\/Clavulanic Acid\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAmpicillin\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAmpicillin\/Sulbactam\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAztreonam\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCefazolin\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCefepime\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCefotaxime\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCeftazidime\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCiprofloxacin\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eColistin\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eErtapenem\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eGentamicin\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eImipenem\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMeropenem\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMinocycline\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePiperacillin\/Tazobactam\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTrimethoprim\/Sulfamethoxazole\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eESBL\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003e\u003cstrong\u003eCLSI panel, Gram positive (QMdRASTP02)\u003c\/strong\u003e\u003c\/p\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eAntibiotic\u003c\/th\u003e\n\u003cth\u003eStaphylococcus spp.\u003c\/th\u003e\n\u003cth\u003eEnterococcus spp.\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eAmpicillin\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCiprofloxacin\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eClindamycin\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eErythromycin\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eGentamicin\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLevofloxacin\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLinezolid\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eOxacillin\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePenicillin\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eRifampin\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTetracycline\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTrimethoprim \/ Sulfamethoxazole\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eVancomycin\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCefoxitin screen\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eGentamicin high-level\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eStreptomycin high-level\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eInducible clindamycin resistance\u003c\/td\u003e\n\u003ctd\u003e✓\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003ch2\u003eWorkflow\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003eClinical workflow\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cimg src=\"https:\/\/www.quantamatrix.com\/wp-content\/uploads\/2022\/07\/drast_workflow_img2_en.jpeg\" alt=\"dRAST clinical workflow\" style=\"max-width:100%;height:auto\" loading=\"lazy\"\u003e\u003c\/p\u003e\u003ch2\u003eClinical evidence\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003edRAST provides susceptibility test results with greater reliability at enhanced speed.\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eAnalysis of susceptibility results generated by conventional testing methods took an average of 64.5 hours while results from dRAST direct from positive blood cultures only took 14.3 hours.\u003c\/p\u003e\u003cp\u003eSusceptibility result from dRAST is not only rapid but also reliable. Compared to Broth Micro-Dilution (BMD), the overall agreement for dRAST was 94.2% (49\/52) and 98.5% (66\/67) for patients with gram-positive and gram-negative bacteremia, respectively.\u003c\/p\u003e\u003cp\u003e\u003cem\u003eKim et al., Journal of Medical Microbiology 2018; 67: 325-331\u003c\/em\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eRapid AST is critical for timely prescribing of optimal, targeted antimicrobials.\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eA prospective study demonstrated the superior impact of dRAST on the selection of optimal antimicrobial therapy for resistant strains compared to Gram staining or MALDI-TOF MS identification.\u003c\/p\u003e\u003cp\u003eThe proportion of optimal targeted treatment was similar between the Gram-staining and the MALDI-TOF MS groups. However, there was significant improvement for the dRAST group compared to the MALDI-TOF MS group. The dRAST group demonstrated a 32% higher rate of optimal, targeted antimicrobial therapy compared to MALDI-TOF and the rate of ineffective therapy was 26% lower.\u003c\/p\u003e\u003cp\u003eThe study demonstrated that result of rapid AST using dRAST contributes significantly more than that of bacterial ID to the administration of optimal targeted antimicrobial treatment.\u003c\/p\u003e\u003cp\u003e\u003cem\u003eKim et al., Journal of Antimicrobial Chemotherapy, Volume 74, Issue 8, August 2019, Pages 2255–2260\u003c\/em\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eRapid AST by dRAST enables successful implementation of antimicrobial stewardship even in the treatment of bacteremia in the immunosuppressed patients.\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eRapid AST by dRAST enables successful implementation of antimicrobial stewardship even for immunosuppressed patients with bacteremia as well as those with underlying hematological disorders.\u003c\/p\u003e\u003cp\u003eDeploying dRAST into the diagnostic process allows more timely management of optimal, targeted treatment. In a recent study, time to initiation of optimal, targeted antimicrobials decreased by 14 hours in the dRAST group (39.0 hrs) compared to the conventional AST group (53.2 hrs).\u003c\/p\u003e\u003cp\u003eIn addition, the proportion of patients receiving optimal, targeted treatment at 48 hours from the first blood draw higher was higher in the dRAST group (66.1%) compared to the conventional AST group (48.3%). Also, the proportion of patients receiving broad-spectrum treatment at 48 hours was lower in the dRAST group (21.4%) compared to the conventional AST group (31.7%).\u003c\/p\u003e\u003cp\u003e\u003cem\u003eKim et al., Clin Microbiol Infect. Volume 27, Issue 1, 2021,Pages 69-75\u003c\/em\u003e\u003c\/p\u003e\u003ch2\u003eDocuments\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.dropbox.com\/s\/1lbzrf69mcydqo3\/DOC-SDGN001EN%20D.pdf?dl=0\" target=\"_blank\" rel=\"noopener\"\u003eSafety Data Sheet, Gram Negative kit (QMdRASTN02)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.dropbox.com\/s\/n2e2f1d2ud0473t\/DOC-SDGP001EN%20D.pdf?dl=0\" target=\"_blank\" rel=\"noopener\"\u003eSafety Data Sheet, Gram Positive kit (QMdRASTP02)\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"QuantaMatrix","offers":[{"title":"Gram Negative","offer_id":67669178253391,"sku":"QMdRASTN02","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Gram Positive","offer_id":67669178286159,"sku":"QMdRASTP02","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/drast_kit_box_img01.jpg?v=1791724233"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/collections\/vendor-logo-quantamatrix.png?v=1791724146","url":"https:\/\/www.danyel.co.il\/collections\/quantamatrix.oembed","provider":"danyel biotech","version":"1.0","type":"link"}