{"title":"QIAGEN","description":null,"products":[{"product_id":"qiagen-qiastat-dx-rise-high-throughput-syndromic-testing-system-9003163","title":"QIAstat-Dx Rise High-Throughput Syndromic Testing System","description":"\u003cp\u003eQIAstat-Dx simplifies infectious disease diagnostics so you can get faster results for your patients. All you need are a patient sample, a QIAstat-Dx assay cartridge and one of our intuitive QIAstat-Dx instruments. \u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003eQIAstat-Dx Rise is our higher-throughput powerhouse, built to fit the needs of high-demand institutions. Combined with QIAstat-Dx assay cartridges, QIAstat-Dx Rise uses multiplex PCR technology – also known as syndromic testing – to quickly survey many different pathogens in a single patient sample. The cartridges come ready with all reagents preloaded and use our trusted assay chemistry. The system includes random access and batch testing options, with a daily capacity of 160 samples using 8 Analytical Modules. The QIAstat-Dx Rise also includes a multi-test front drawer that can accommodate up to 18 cartridges at the same time, and a waste drawer to automatically collect used cartridges.\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003eEach instrument is made up of two components: 1) A QIAstat-Dx Rise Base, which contains the intuitive touch-screen interface and robotic system that moves and scans the cartridges within the device and 2) Between 1 through 8 Analytical Modules, letting you test up to eight samples at once. \u003c\/p\u003e\n\u003cp\u003eWith QIAstat-Dx Rise in your lab, you can: \u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eGain time away from your instruments\u003c\/strong\u003e: Batch process up to 16 cartridges using 8 Analytical modules.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProcess priority tests fast\u003c\/strong\u003e: Get random access through 2 additional urgent testing slots. \u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLoad and go:\u003c\/strong\u003e Load the full capacity of cartridges in just a few minutes and safely dispose of used tests in one step.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003ePlus, every QIAstat-Dx Analytical Module is compatible with both QIAstat-Dx Analyzer 2.0 and QIAstat-Dx Rise. Easily update your QIAstat-Dx testing format based on your evolving testing needs. \u003ca href=\"https:\/\/www.qiagen.com\/products\/diagnostics-and-clinical-research\/infectious-disease\/qiastat-dx-syndromic-testing\/qiastat-dx\" rel=\"noopener\" target=\"_blank\"\u003eClick here\u003c\/a\u003e to more about QIAstat-Dx Analyzer 2.0, our modular system perfect for labs of every size.\u003c\/p\u003e\u003cp\u003eThe QIAstat-Dx Rise Base is a benchtop in vitro diagnostic device for use with QIAstat-Dx assays and QIAstat-Dx Analytical Modules. It provides full automation from sample preparation to real-time PCR detection. This higher-throughput system can accommodate up to 160 patient samples per day using 8 Analytical Modules.\u003c\/p\u003e\u003ch2\u003eFeatures\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eUses real-time PCR to deliver comprehensive results for up to 160 patient samples per day with 8 Analytical Modules\u003c\/li\u003e\n\u003cli\u003eEasily view Ct values and amplification curves for all detected pathogens\u003c\/li\u003e\n\u003cli\u003eSingle-step cartridge preparation with no precision pipetting required and unique direct swab protocol\u003c\/li\u003e\n\u003cli\u003eLoad the full capacity of cartridges in just a few minutes and safely dispose of all used cartridges from the waste tray in one quick step\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003ePrinciple\u003c\/h2\u003e\u003cp\u003eQIAstat-Dx Rise, combined with QIAstat-Dx assay cartridges, uses real-time PCR to detect pathogen nucleic acids in human biological samples. The instrument and cartridges are designed as a closed system that contain on board all necessary reagents, enabling hands-off sample preparation. Detected real-time amplification signals are interpreted by the integrated software and are reported via an intuitive user interface.\u003c\/p\u003e\u003ch2\u003eProcedure\u003c\/h2\u003e\u003cp\u003ePreparing a QIAstat-Dx cartridge using liquid transfer or dry swab sample application is efficient and fast. And once the cartridges are ready, it takes just a few minutes to load the full capacity of cartridges and start a run on QIAstat-Dx Rise. \u003c\/p\u003e\n\u003cp\u003eLoading a sample into the QIAstat-Dx cartridge requires less than one minute hands-on time with no precision pipetting.\u003c\/p\u003e\n\u003cp\u003eUsing the provided transfer pipette, the user applies a liquid sample to the main port of the QIAstat-Dx cartridge (see Applying a liquid sample to the QIAstat-Dx cartridge). Alternatively for our respiratory assay, a dry swab sample may be directly applied to the cartridge (Applying a dry swab to the QIAstat-Dx cartridge).\u003c\/p\u003e\n\u003cp\u003eFollowing the instructions on the QIAstat-Dx Rise touchscreen display, the user loads the prepared cartridges into the instrument’s loading tray (see Adding cartridges to the QIAstat-Dx Rise input tray).\u003c\/p\u003e\n\u003cp\u003eThe QIAstat-Dx Rise will automatically scan the sample ID and cartridge barcodes, or the user can manually scan the barcodes. Once the user starts the run, the QIAstat-Dx Rise will autonomously process the samples. \u003c\/p\u003e\n\u003cp\u003eThe input tray also offers random and continuous access, meaning an urgent test can be added to an ongoing run at a moment’s notice. \u003c\/p\u003e\n\u003cp\u003eOnce the run is finished, the used cartridges are automatically placed in the dedicated waste tray so they can be disposed of safely and quickly.\u003c\/p\u003e\u003ch2\u003eApplications\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003eQIAstat-Dx Respiratory SARS-CoV-2 Panel (V2)\u003c\/strong\u003e: Qualitative test to analyze 23 viral and bacterial respiratory targets for common pathogens causing respiratory infections, including SARS-CoV-2.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eQIAstat-Dx Respiratory SARS-CoV-2 Panel (V2) – 23 bacterial and viral pathogens\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eViruses\u003c\/th\u003e\n\u003ctd\u003e \u003c\/td\u003e\n\u003cth\u003eBacteria\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eInfluenza A\u003c\/td\u003e\n\u003ctd\u003eParainfluenza virus 1\u003c\/td\u003e\n\u003ctd\u003e \u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eInfluenza A subtype H1N1\/2009\u003c\/td\u003e\n\u003ctd\u003eParainfluenza virus 2\u003c\/td\u003e\n\u003ctd\u003e \u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eInfluenza A subtype H1\u003c\/td\u003e\n\u003ctd\u003eParainfluenza virus 3\u003c\/td\u003e\n\u003ctd\u003e \u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eInfluenza A subtype H3\u003c\/td\u003e\n\u003ctd\u003eParainfluenza virus 4\u003c\/td\u003e\n\u003ctd\u003e\u003cem\u003eMycoplasma pneumoniae\u003c\/em\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eInfluenza B\u003c\/td\u003e\n\u003ctd\u003eRespiratory syncytial virus A\/B\u003c\/td\u003e\n\u003ctd\u003e\u003cem\u003eLegionella pneumophilia\u003c\/em\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCoronavirus 229E\u003c\/td\u003e\n\u003ctd\u003eHuman metapneumovirus A\/B\u003c\/td\u003e\n\u003ctd\u003e\u003cem\u003eBordetella pertussis\u003c\/em\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCoronavirus HKU1\u003c\/td\u003e\n\u003ctd\u003eAdenovirus\u003c\/td\u003e\n\u003ctd\u003e\u003cem\u003eChlamydophila pneumoniae\u003c\/em\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCoronavirus NL63\u003c\/td\u003e\n\u003ctd\u003eBocavirus\u003c\/td\u003e\n\u003ctd\u003e \u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCoronavirus OC43\u003c\/td\u003e\n\u003ctd\u003eRhinovirus\/Enterovirus*\u003c\/td\u003e\n\u003ctd\u003e \u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eSARS-CoV-2\u003c\/td\u003e\n\u003ctd\u003e \u003c\/td\u003e\n\u003ctd\u003e \u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e*Enterovirus and Rhinovirus are both detected, but not differentiated, with the QIAstat-Dx Respiratory SARS-CoV-2 Panel.\u003c\/p\u003e\n\u003cp\u003eThe QIAstat-Dx Respiratory SARS-CoV-Panel (V2) is currently available in select countries.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eQIAstat-Dx Gastrointestinal Panel 2\u003c\/strong\u003e: Qualitative test to analyze 22 of the most common pathogens causing gastrointestinal infections, including differentiation of Shiga-like toxin producing \u003cem\u003eE. coli\u003c\/em\u003e (STEC) stx1 and stx2.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eQIAstat-Dx Gastrointestinal Panel 2 – 23 targets, corresponding to 22 bacterial, viral and parasitic pathogens\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eBacteria\u003c\/th\u003e\n\u003cth\u003e \u003c\/th\u003e\n\u003cth\u003eViruses\u003c\/th\u003e\n\u003cth\u003eParasites\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cem\u003eCampylobacter (C. jejuni, C. upsaliensis, C. coli)\u003c\/em\u003e\u003c\/td\u003e\n\u003ctd\u003e\n\u003cem\u003eSalmonella \u003c\/em\u003espp.\u003c\/td\u003e\n\u003ctd\u003e\u003cem\u003eAdenovirus F40\/41\u003c\/em\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cem\u003eCryptosporidium\u003c\/em\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003cem\u003eClostridium difficile\u003c\/em\u003e (toxin A\/B)\u003c\/td\u003e\n\u003ctd\u003eShiga-like toxin-producing \u003cem\u003eE. coli\u003c\/em\u003e (STEC) stx1 and stx2 (including specific identification of \u003cem\u003eE. coli\u003c\/em\u003e O157 serogroup within STEC)**\u003c\/td\u003e\n\u003ctd\u003eAstrovirus\u003c\/td\u003e\n\u003ctd\u003e\u003cem\u003eCyclospora cayetanensis\u003c\/em\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eEnteroaggregative \u003cem\u003eE. coli\u003c\/em\u003e (EAEC)\u003c\/td\u003e\n\u003ctd\u003e\u003cem\u003eVibrio vulnificus\u003c\/em\u003e\u003c\/td\u003e\n\u003ctd\u003eNorovirus (GI, GII)\u003c\/td\u003e\n\u003ctd\u003e\u003cem\u003eEntamoeba histolytica\u003c\/em\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003cem\u003eShigella\u003c\/em\u003e\/Enteroinvasive \u003cem\u003eE. coli\u003c\/em\u003e (EIEC)\u003c\/td\u003e\n\u003ctd\u003e\u003cem\u003eVibrio parahaemolyticus\u003c\/em\u003e\u003c\/td\u003e\n\u003ctd\u003eRotavirus A\u003c\/td\u003e\n\u003ctd\u003e\u003cem\u003eGiardia lamblia\u003c\/em\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eEnteropathogenic \u003cem\u003eE. coli\u003c\/em\u003e (EPEC)\u003c\/td\u003e\n\u003ctd\u003e\u003cem\u003eVibrio cholerae\u003c\/em\u003e\u003c\/td\u003e\n\u003ctd\u003eSapovirus (GI, GII, GIV, GV)\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eEnterotoxigenic \u003cem\u003eE. coli\u003c\/em\u003e (ETEC) \u003cem\u003elt\/st\u003c\/em\u003e\n\u003c\/td\u003e\n\u003ctd\u003e\u003cem\u003eYersinia enterocolitica\u003c\/em\u003e\u003c\/td\u003e\n\u003ctd\u003e \u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cem\u003ePlesiomonas shigelloides\u003c\/em\u003e\u003c\/td\u003e\n\u003ctd\u003e \u003c\/td\u003e\n\u003ctd\u003e \u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e**The stx1 and stx2 toxin genes of STEC are reported separately by the QIAstat-Dx Gastrointestinal Panel 2.\u003c\/p\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eFeatures\u003c\/th\u003e\n\u003cth\u003eSpecifications\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eConfiguration\u003c\/td\u003e\n\u003ctd\u003eModular syndromic testing system with QIAstat-Dx Rise Base, up to 8 QIAstat-Dx Analytical Modules and 1 QIAstat-Dx Rise Mobile Table (optional).\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eInstrument dimensions (WxHxD)\u003c\/td\u003e\n\u003ctd\u003eQIAstat-Dx Rise Base (door closed): 580 x 1280 x 810 mm (22.8 x 50.4 x 31.9 in) \u003cbr\u003eQIAstat-Dx Rise Base (door open): 1500 mm x 1280 x 810 mm (59 x 50.4 x 31.9 in)\u003cbr\u003eFor installation and service interventions, 1.5 m of space around the instrument is required.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWeight\u003c\/td\u003e\n\u003ctd\u003eQIAstat-Dx Rise Base: 130 kg\u003cbr\u003eQIAstat-Dx Analytical Module: 16 kg\u003cbr\u003eQIAstat-Dx Rise Mobile Table (load-bearing capacity): 300 kg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePower requirements\u003c\/td\u003e\n\u003ctd\u003e200–240 VAC\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eRecommended clearance\u003c\/td\u003e\n\u003ctd\u003eLeft side: 80 cm\u003cbr\u003eTop: 32 cm\u003cbr\u003eFront: 140 cm\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eOperating conditions\u003c\/th\u003e\n\u003cth\u003eSpecifications\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAir temperature\u003c\/td\u003e\n\u003ctd\u003e15–28 ̊C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eRelative humidity\u003c\/td\u003e\n\u003ctd\u003e20–80%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAltitude\u003c\/td\u003e\n\u003ctd\u003e0–2200 m\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePlace of operation\u003c\/td\u003e\n\u003ctd\u003eLaboratory (inside)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003ch2\u003eDocuments\u003c\/h2\u003e\u003cul\u003e\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/gb\/resources\/usermanual\/hb-3570-001-qsg-qiastat-dx-rise-0524\" target=\"_blank\" rel=\"noopener\"\u003eQIAstat-Dx Rise Quick-Start Guide\u003c\/a\u003e\u003c\/li\u003e\u003c\/ul\u003e\u003ch2\u003eOrdering Information\u003c\/h2\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eCat. no.\u003c\/th\u003e\n\u003cth\u003eProduct\u003c\/th\u003e\n\u003cth\u003eContents\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\u003ctr\u003e\n\u003ctd\u003e9003163\u003c\/td\u003e\n\u003ctd\u003eQIAstat-Dx Rise Base\u003c\/td\u003e\n\u003ctd\u003eThe QIAstat-Dx Rise Base is a benchtop in vitro diagnostic device for use with QIAstat-Dx assays and QIAstat-Dx Analytical Modules. It provides full automation from sample preparation to real-time PCR detection. This higher-throughput system can accommodate up to 160 patient samples per day using 8 Analytical Modules.\u003c\/td\u003e\n\u003c\/tr\u003e\u003c\/tbody\u003e\n\u003c\/table\u003e","brand":"QIAGEN","offers":[{"title":"Default Title","offer_id":46798467203151,"sku":"9003163","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/1_5_WebFullSizeImage.jpg?v=1789653374"},{"product_id":"qiagen-qiastat-dx-analyzer-2-0-syndromic-testing-system-9002828","title":"QIAstat-Dx Analyzer 2.0 Syndromic Testing System","description":"\u003cp\u003eQIAstat-Dx simplifies infectious disease diagnostics so you can get faster results for your patients. All you need are a patient sample, a QIAstat-Dx assay cartridge and our intuitive QIAstat-Dx instrument.\u003c\/p\u003e\n\u003cp\u003eThe QIAstat-Dx assay cartridges use multiplex PCR technology – also known as syndromic testing – to quickly survey many different pathogens in a single patient sample. The cartridges come ready with preloaded reagents and use our trusted assay chemistry to provide comprehensive results in about an hour.\u003c\/p\u003e\n\u003cp\u003eAnd now you can see critical results even faster with the QIAstat-Dx Analyzer 2.0. With our new Operational Module PRO at the helm, the QIAstat-Dx Analyzer 2.0 blends all the QIAstat-Dx features our customers love with some exciting upgrades. This enhanced QIAstat-Dx instrument introduces our \u003ca href=\"https:\/\/www.qiagen.com\/applications\/syndromic-testing\/products\/qiastat-dx-connectivity\" rel=\"noopener\" target=\"_blank\"\u003eRemote Results Application\u003c\/a\u003e*, which merges lab accuracy with clinical speed. Now you can review and confirm patient results from any location, paving the way for effortless collaboration between central and regional labs. The QIAstat-Dx Analyzer 2.0 is more than just an upgrade – it’s a giant leap towards a smarter, more interconnected healthcare future.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eBreak boundaries:\u003c\/strong\u003e Review and approve results from anywhere with the Remote Results Application, powered by QIAsphere.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStay in the know:\u003c\/strong\u003e Automatically receive notifications and software updates on your instruments.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCustomize to your heart’s desire:\u003c\/strong\u003e Easily switch languages, user roles, instrument configurations and more.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eYou’ll save even more time with \u003ca href=\"https:\/\/www.qiagen.com\/applications\/syndromic-testing\/products\/qiastat-dx-connectivity\" rel=\"noopener\" target=\"_blank\"\u003eQIAstat-Dx connectivity\u003c\/a\u003e, powered by QIAsphere*. With QIAstat-Dx connectivity, you can remotely monitor your instruments in real-time, receive proactive technical support and get on-demand epidemiology reports to support your institution-wide surveillance efforts. Simply install the QIAsphere app on your preferred tablet or smartphone or by accessing the QIAsphere web app through your laptop or desktop browser.\u003c\/p\u003e\n\u003cp\u003e*Some features require a QIAstat-Dx Connectivity plan. Flexible plans are available to meet your needs.\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/www.qiagen.com\/applications\/syndromic-testing\/syndromic-testing-benefits\" rel=\"noopener\" target=\"_blank\"\u003eVisit our resource hub\u003c\/a\u003e to learn how syndromic testing with QIAstat-Dx can help you provide the best care possible for your patients.\u003c\/p\u003e\u003cp\u003eInstrument consists of both the Operational Module PRO and one Analytical Module.\u003c\/p\u003e\u003ch2\u003eFeatures\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eIntuitive workflow with minimal hands-on time\u003c\/li\u003e\n\u003cli\u003eUses real-time PCR to deliver comprehensive results in about an hour\u003c\/li\u003e\n\u003cli\u003eEasily view Ct values and amplification curves for all detected pathogens\u003c\/li\u003e\n\u003cli\u003eNo precision pipetting required and unique direct swab protocol for input into the cartridge\u003c\/li\u003e\n\u003cli\u003eQIAsphere-connected for real-time updates, proactive remote service and custom epidemiology reports\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003ePrinciple\u003c\/h2\u003e\u003cp\u003eThe QIAstat-Dx Analyzers 1.0 and 2.0, combined with QIAstat-Dx assay cartridges, use real-time PCR to detect pathogen nucleic acids in human biological samples. The cartridges are designed as closed systems containing the necessary reagents for automated sample processing, following a simple sample preparation and loading step.  Detected real-time amplification signals are interpreted by the integrated software and are reported via an intuitive user interface.\u003c\/p\u003e\u003ch2\u003eProcedure\u003c\/h2\u003e\u003cp\u003eSetting up and running a QIAstat-Dx test requires minimal hands-on time and just a few simple steps. \u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003eAdd the patient sample to the main port of the QIAstat-Dx cartridge using the plastic pipette provided. For our respiratory panels, you can alternatively apply the sample with a dry swab. This step is fast and easy to perform and requires no precision pipetting.\u003c\/li\u003e\n\u003cli\u003ePress the Run Test button on the QIAstat-Dx touch screen and scan the sample ID barcode.\u003c\/li\u003e\n\u003cli\u003eScan the barcode of the cartridge you’re using.\u003c\/li\u003e\n\u003cli\u003ePosition the cartridge on the instrument’s sample port. The cartridge will automatically move in and the test will start.\u003c\/li\u003e\n\u003cli\u003eAfter about an hour, view the comprehensive results.\u003c\/li\u003e\n\u003c\/ol\u003e\u003ch2\u003eCompatible Panels\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eQIAstat-Dx Respiratory SARS-CoV-2 Panel\u003c\/li\u003e\n\u003cli\u003eQIAstat-Dx Respiratory Panel Plus\u003c\/li\u003e\n\u003cli\u003eQIAstat-Dx Respiratory Panel Mini\u003c\/li\u003e\n\u003cli\u003eQIAstat-Dx Gastrointestinal Panel 2\u003c\/li\u003e\n\u003cli\u003eQIAstat-Dx Gastrointestinal Panel 2 Mini\u003c\/li\u003e\n\u003cli\u003eQIAstat-Dx Meningitis\/Encephalitis Panel\u003c\/li\u003e\n\u003cli\u003eQIAstat-Dx Viral Vesicular Panel\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eDocuments\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/gb\/resources\/usermanual\/hb-3359-002-um-qiastatdx-analyzersw-v160-ce-0824\" target=\"_blank\" rel=\"noopener\"\u003eQIAstat-Dx Analyzer 2.0 User Manual\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/gb\/resources\/usermanual\/hb-3360-001-ug-qiastat-dx-remote-results-app-0124-ce-row\" target=\"_blank\" rel=\"noopener\"\u003eQIAstat-Dx Remote Results Application User Guide\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eOrdering Information\u003c\/h2\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eCat. no.\u003c\/th\u003e\n\u003cth\u003eProduct\u003c\/th\u003e\n\u003cth\u003eContents\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\u003ctr\u003e\n\u003ctd\u003e9002828\u003c\/td\u003e\n\u003ctd\u003eQIAstat-Dx Analyzer 2.0\u003c\/td\u003e\n\u003ctd\u003eInstrument consists of both the Operational Module PRO and one Analytical Module.\u003c\/td\u003e\n\u003c\/tr\u003e\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003e\u003cem\u003eThe QIAstat-Dx instruments and QIAstat-Dx panels are intended for in vitro diagnostic use. \u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eFor up-to-date licensing information and product-specific disclaimers, see the respective QIAGEN kit instructions for use or user manual. QIAGEN instructions for use and user manuals are available at www.qiagen.com or can be requested from QIAGEN Technical Services (or your local distributor). \u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eProduct availability may differ from country to country based on regulations and approvals. Contact your country representative for further details.\u003c\/em\u003e\u003c\/p\u003e","brand":"QIAGEN","offers":[{"title":"Default Title","offer_id":46798467235919,"sku":"9002828","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/1_5_WebFullSizeImage_728c1f51-a9ed-459a-8c57-df4918ba282d.jpg?v=1789653374"},{"product_id":"qiagen-qiastat-dx-respiratory-sars-cov-2-panel-691214","title":"QIAstat-Dx Respiratory SARS-CoV-2 Panel","description":"\u003cp\u003e\u003cstrong\u003eQIAstat-Dx Respiratory SARS-CoV-2 Panel\u003c\/strong\u003e – Qualitative test to analyze 23 viral and bacterial respiratory targets for common pathogens causing respiratory infections, including SARS-CoV-2.\u003c\/p\u003e\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth colspan=\"3\"\u003eQIAstat-Dx Respiratory SARS-CoV-2 Panel – 23 bacterial and viral pathogens\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth colspan=\"2\"\u003eViruses\u003c\/th\u003e\n\u003cth\u003eBacteria\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003cp\u003eInfluenza A\u003c\/p\u003e\n\u003cp\u003eInfluenza A subtype H1N1\/2009\u003c\/p\u003e\n\u003cp\u003eInfluenza A subtype H1\u003c\/p\u003e\n\u003cp\u003eInfluenza A subtype H3\u003c\/p\u003e\n\u003cp\u003eInfluenza B\u003c\/p\u003e\n\u003cp\u003eCoronavirus 229E\u003c\/p\u003e\n\u003cp\u003eCoronavirus HKU1\u003c\/p\u003e\n\u003cp\u003eCoronavirus NL63\u003c\/p\u003e\n\u003cp\u003eCoronavirus OC43\u003c\/p\u003e\n\u003cp\u003eSARS-CoV-2\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd\u003e\n\u003cp\u003eParainfluenza virus 1\u003c\/p\u003e\n\u003cp\u003eParainfluenza virus 2\u003c\/p\u003e\n\u003cp\u003eParainfluenza virus 3\u003c\/p\u003e\n\u003cp\u003eParainfluenza virus 4\u003c\/p\u003e\n\u003cp\u003eRespiratory syncytial virus A\/B\u003c\/p\u003e\n\u003cp\u003eHuman metapneumovirus A\/B\u003c\/p\u003e\n\u003cp\u003eAdenovirus\u003c\/p\u003e\n\u003cp\u003eBocavirus\u003c\/p\u003e\n\u003cp\u003eRhinovirus\/Enterovirus*\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd\u003e\n\u003cp\u003e\u003cem\u003eMycoplasma pneumoniae \u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eLegionella pneumophilia \u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eBordetella pertussis \u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eChlamydophila pneumoniae\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003e*Enterovirus and Rhinovirus are both detected, but not differentiated, with the QIAstat-Dx Respiratory SARS-CoV-2 Panel.\u003c\/p\u003e\u003cp\u003e6 individually packaged cartridges containing all reagents needed for sample preparation and multiplex real-time RT-PCR plus internal control, including 6 transfer pipettes.\u003c\/p\u003e\u003ch2\u003eFeatures\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eIntuitive workflow with minimal hands-on time\u003c\/li\u003e\n\u003cli\u003eUses real-time PCR to deliver comprehensive results in about an hour\u003c\/li\u003e\n\u003cli\u003eEasily view Ct values and amplification curves for all detected pathogens\u003c\/li\u003e\n\u003cli\u003eNo precision pipetting required and unique direct swab protocol for input into the cartridge\u003c\/li\u003e\n\u003cli\u003eQIAsphere-connected for real-time updates, proactive remote service and custom epidemiology reports\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003ePrinciple\u003c\/h2\u003e\u003cp\u003eThe QIAstat-Dx Analyzers 1.0 and 2.0, combined with QIAstat-Dx assay cartridges, use real-time PCR to detect pathogen nucleic acids in human biological samples. The cartridges are designed as closed systems containing the necessary reagents for automated sample processing, following a simple sample preparation and loading step.  Detected real-time amplification signals are interpreted by the integrated software and are reported via an intuitive user interface.\u003c\/p\u003e\u003ch2\u003eProcedure\u003c\/h2\u003e\u003cp\u003eSetting up and running a QIAstat-Dx test requires minimal hands-on time and just a few simple steps. \u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003eAdd the patient sample to the main port of the QIAstat-Dx cartridge using the plastic pipette provided. For our respiratory panels, you can alternatively apply the sample with a dry swab. This step is fast and easy to perform and requires no precision pipetting.\u003c\/li\u003e\n\u003cli\u003ePress the Run Test button on the QIAstat-Dx touch screen and scan the sample ID barcode.\u003c\/li\u003e\n\u003cli\u003eScan the barcode of the cartridge you’re using.\u003c\/li\u003e\n\u003cli\u003ePosition the cartridge on the instrument’s sample port. The cartridge will automatically move in and the test will start.\u003c\/li\u003e\n\u003cli\u003eAfter about an hour, view the comprehensive results.\u003c\/li\u003e\n\u003c\/ol\u003e\u003ch2\u003eDocuments\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/gb\/resources\/kithandbookandprotocol\/hb-2934-003-v2-r1-hb-qiastat-dx-sars-cov-2-ce-0124-row\" target=\"_blank\" rel=\"noopener\"\u003eQIAstat-Dx Respiratory SARS-CoV-2 Panel (Version 2) Instructions for Use (Handbook)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/gb\/resources\/kithandbookandprotocol\/hb-2773-002-r2-hb-qiastat-dx-sars-cov-2-ce-1220-row\" target=\"_blank\" rel=\"noopener\"\u003eQIAstat-Dx Respiratory SARS-CoV-2 Panel Instructions for Use (Handbook)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/gb\/resources\/scientificdocument\/prom-23510-001-an-qsdx-respi-ceivd-verifcation-controls-st-qpro-9200-1224-row\" target=\"_blank\" rel=\"noopener\"\u003eGuidelines for Laboratory Verification of Performance of QIAstat-Dx Respiratory SARS-CoV-2 Panel\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eOrdering Information\u003c\/h2\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eCat. no.\u003c\/th\u003e\n\u003cth\u003eProduct\u003c\/th\u003e\n\u003cth\u003eContents\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\u003ctr\u003e\n\u003ctd\u003e691214\u003c\/td\u003e\n\u003ctd\u003eQIAstat-Dx Respiratory SARS-CoV-2 Panel\u003c\/td\u003e\n\u003ctd\u003e6 individually packaged cartridges containing all reagents needed for sample preparation and multiplex real-time RT-PCR plus internal control, including 6 transfer pipettes\u003c\/td\u003e\n\u003c\/tr\u003e\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003e\u003cem\u003eThe QIAstat-Dx instruments and QIAstat-Dx panels are intended for in vitro diagnostic use. \u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eFor up-to-date licensing information and product-specific disclaimers, see the respective QIAGEN kit instructions for use or user manual. QIAGEN instructions for use and user manuals are available at www.qiagen.com or can be requested from QIAGEN Technical Services (or your local distributor). \u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eProduct availability may differ from country to country based on regulations and approvals. Contact your country representative for further details.\u003c\/em\u003e\u003c\/p\u003e","brand":"QIAGEN","offers":[{"title":"Default Title","offer_id":46798467825743,"sku":"691214","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/1_5_WebFullSizeImage_74021754-c3b4-47be-8fee-eb1c33e911df.jpg?v=1789653380"},{"product_id":"qiagen-qiastat-dx-respiratory-panel-plus-691224","title":"QIAstat-Dx Respiratory Panel Plus","description":"\u003cp\u003e\u003cstrong\u003eQIAstat-Dx Respiratory Panel Plus\u003c\/strong\u003e – FDA-cleared test to analyze 21 viral and bacterial targets for common pathogens causing respiratory symptoms, including SARS-CoV-2.\u003c\/p\u003e\u003ctable\u003e\n\u003ccaption\u003e\n\u003cstrong\u003eQIAstat-Dx Respiratory Panel Plus\u003c\/strong\u003e – 21 bacterial and viral targets\u003c\/caption\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003ctd colspan=\"2\"\u003eViruses\u003c\/td\u003e\n\u003ctd\u003eBacteria\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003cul\u003e\n\u003cli\u003eSevere Acute Respiratory Syndrome Coronavirus (SARS-CoV-2)\u003c\/li\u003e\n\u003cli\u003eInfluenza A\u003c\/li\u003e\n\u003cli\u003eInfluenza A H1N1 pdm09\u003c\/li\u003e\n\u003cli\u003eInfluenza A H1\u003c\/li\u003e\n\u003cli\u003eInfluenza A H3\u003c\/li\u003e\n\u003cli\u003eInfluenza B\u003c\/li\u003e\n\u003cli\u003eHuman Coronavirus 229E\u003c\/li\u003e\n\u003cli\u003eHuman Coronavirus HKU1\u003c\/li\u003e\n\u003cli\u003eHuman Coronavirus NL63\u003c\/li\u003e\n\u003cli\u003eHuman Coronavirus OC43\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/td\u003e\n\u003ctd\u003e\n\u003cul\u003e\n\u003cli\u003eParainfluenza virus 1\u003c\/li\u003e\n\u003cli\u003eParainfluenza virus 2\u003c\/li\u003e\n\u003cli\u003eParainfluenza virus 3\u003c\/li\u003e\n\u003cli\u003eParainfluenza virus 4\u003c\/li\u003e\n\u003cli\u003eAdenovirus\u003c\/li\u003e\n\u003cli\u003eRespiratory syncytial virus\u003c\/li\u003e\n\u003cli\u003eHuman metapneumovirus\u003c\/li\u003e\n\u003cli\u003eHuman Rhinovirus\/Enterovirus (not differentiated)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/td\u003e\n\u003ctd\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cem\u003eMycoplasma pneumoniae\u003c\/em\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cem\u003eBordetella pertussis\u003c\/em\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cem\u003eChlamydophila pneumoniae\u003c\/em\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003eThis version of our assay replaces the QIAstat-Dx Respiratory SARS-CoV-2 Panel. \u003c\/p\u003e\u003cp\u003eThe QIAstat-Dx Respiratory Panel Plus can be used on the QIAstat-Dx Analyzer 1.0, QIAstat-Dx Analyzer 2.0 and QIAstat-Dx Rise.\u003c\/p\u003e\u003cp\u003e6 individually packaged cartridges containing all reagents needed for sample preparation and multiplex RT-PCR, plus internal control, including six transfer pipettes.\u003c\/p\u003e\u003ch2\u003eFeatures\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eIntuitive workflow with minimal hands-on time\u003c\/li\u003e\n\u003cli\u003eUses RT-PCR to deliver comprehensive results in about an hour\u003c\/li\u003e\n\u003cli\u003eProvides Ct values and amplification curves for all detected pathogens directly on the instrument touchscreen\u003c\/li\u003e\n\u003cli\u003eNo precision pipetting required\u003c\/li\u003e\n\u003cli\u003eQIAsphere-connected for real-time updates and custom epidemiology reports*\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003ePrinciple\u003c\/h2\u003e\u003cp\u003eThe QIAstat-Dx Analyzer 2.0, combined with QIAstat-Dx assay cartridges, use real-time PCR to detect pathogen nucleic acids in human biological samples. The QIAstat-Dx Analyzer 2.0 and cartridges are designed as closed systems that contain all necessary reagents, enabling hands-off sample preparation. Detected real-time amplification signals are interpreted by the integrated software and are reported via an intuitive user interface.\u003c\/p\u003e\u003ch2\u003eProcedure\u003c\/h2\u003e\u003cp\u003eSetting up and running a QIAstat-Dx test requires minimal hands-on time and just a few simple steps.\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003eAdd the patient sample to the main port of the QIAstat-Dx cartridge using the plastic pipette provided. This step is fast and easy to perform and requires no precision pipetting.\u003c\/li\u003e\n\u003cli\u003ePress the Run Test button on the QIAstat-Dx touch screen and scan the sample ID barcode.\u003c\/li\u003e\n\u003cli\u003eScan the barcode of the cartridge you’re using.\u003c\/li\u003e\n\u003cli\u003eFor our QIAstat-Dx Gastrointestinal Panel 2 test, select the sample type (Para-Pak C\u0026amp;S or FecalSwab).\u003c\/li\u003e\n\u003cli\u003ePosition the cartridge on the instrument’s sample port. The cartridge will automatically move in and the test will start.\u003c\/li\u003e\n\u003cli\u003eAfter about an hour, view the comprehensive results.\u003c\/li\u003e\n\u003c\/ol\u003e\u003ch2\u003eDocuments\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/kithandbookandprotocol\/hb-3474-003-hb-r3-qiastatdx-respipanelplus-0825-us\" target=\"_blank\" rel=\"noopener\"\u003eQIAstat-Dx Respiratory Panel Plus Instructions for Use\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/scientificdocument\/qiastatdx-rp-plus-an-lv-us\" target=\"_blank\" rel=\"noopener\"\u003eGuidelines for Laboratory Verification of Performance of QIAstat-Dx Respiratory Panel Plus\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/kithandbookandprotocol\/hb-3598-003-r3-qiastatdx-respi-panel-mini-0825-us\" target=\"_blank\" rel=\"noopener\"\u003eQIAstat-Dx Respiratory Panel Mini Instructions for Use\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/scientificdocument\/qiastatdx-rp-mini-an-lv-us\" target=\"_blank\" rel=\"noopener\"\u003eGuidelines for Laboratory Verification of Performance of QIAstat-Dx Respiratory Panel Mini\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eOrdering Information\u003c\/h2\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eCat. no.\u003c\/th\u003e\n\u003cth\u003eProduct\u003c\/th\u003e\n\u003cth\u003eContents\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\u003ctr\u003e\n\u003ctd\u003e691224\u003c\/td\u003e\n\u003ctd\u003eQIAstat-Dx Respiratory Panel Plus\u003c\/td\u003e\n\u003ctd\u003e6 individually packaged cartridges containing all reagents needed for sample preparation and multiplex RT-PCR, plus internal control, including six transfer pipettes.\u003c\/td\u003e\n\u003c\/tr\u003e\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003e\u003cem\u003eQIAstat-Dx instruments and QIAstat-Dx panels are intended for in vitro diagnostic use.\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eFor up-to-date licensing information and product-specific disclaimers, see the respective QIAGEN kit instructions for use or user manual. QIAGEN instructions for use and user manuals are available at www.qiagen.com or can be requested from QIAGEN Technical Services (or your local distributor).\u003c\/em\u003e\u003c\/p\u003e","brand":"QIAGEN","offers":[{"title":"Default Title","offer_id":46798467858511,"sku":"691224","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/1_5_WebFullSizeImage_e977a351-5c74-4204-bee0-9f3c284df604.jpg?v=1789653380"},{"product_id":"qiagen-qiastat-dx-respiratory-panel-mini-691218","title":"QIAstat-Dx Respiratory Panel Mini","description":"\u003cp\u003e\u003cstrong\u003eQIAstat-Dx Respiratory Panel Mini\u003c\/strong\u003e – FDA-cleared test to analyze 5 viral targets for common pathogens causing respiratory symptoms, including Human Rhinovirus. This targeted panel is ideal for low-risk patients.\u003c\/p\u003e\u003ctable\u003e\n\u003ccaption\u003e\n\u003cstrong\u003eQIAstat-Dx Respiratory Panel Mini\u003c\/strong\u003e – 5 viral targets\u003c\/caption\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003ctd\u003eViruses \u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003cul\u003e\n\u003cli\u003eSevere Acute Respiratory Syndrome Coronavirus (SARS-CoV-2)  \u003c\/li\u003e\n\u003cli\u003eInfluenza A  \u003c\/li\u003e\n\u003cli\u003eInfluenza B\u003c\/li\u003e\n\u003cli\u003eRespiratory syncytial virus\u003c\/li\u003e\n\u003cli\u003eHuman Rhinovirus \u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003e6 individually packaged cartridges containing all reagents needed for sample preparation and multiplex RT-PCR, plus internal control, including six transfer pipettes.\u003c\/p\u003e\u003ch2\u003eFeatures\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eIntuitive workflow with minimal hands-on time\u003c\/li\u003e\n\u003cli\u003eUses RT-PCR to deliver comprehensive results in about an hour\u003c\/li\u003e\n\u003cli\u003eProvides Ct values and amplification curves for all detected pathogens directly on the instrument touchscreen\u003c\/li\u003e\n\u003cli\u003eNo precision pipetting required\u003c\/li\u003e\n\u003cli\u003eQIAsphere-connected for real-time updates and custom epidemiology reports*\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003ePrinciple\u003c\/h2\u003e\u003cp\u003eThe QIAstat-Dx Analyzer 2.0, combined with QIAstat-Dx assay cartridges, use real-time PCR to detect pathogen nucleic acids in human biological samples. The QIAstat-Dx Analyzer 2.0 and cartridges are designed as closed systems that contain all necessary reagents, enabling hands-off sample preparation. Detected real-time amplification signals are interpreted by the integrated software and are reported via an intuitive user interface.\u003c\/p\u003e\u003ch2\u003eProcedure\u003c\/h2\u003e\u003cp\u003eSetting up and running a QIAstat-Dx test requires minimal hands-on time and just a few simple steps.\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003eAdd the patient sample to the main port of the QIAstat-Dx cartridge using the plastic pipette provided. This step is fast and easy to perform and requires no precision pipetting.\u003c\/li\u003e\n\u003cli\u003ePress the Run Test button on the QIAstat-Dx touch screen and scan the sample ID barcode.\u003c\/li\u003e\n\u003cli\u003eScan the barcode of the cartridge you’re using.\u003c\/li\u003e\n\u003cli\u003eFor our QIAstat-Dx Gastrointestinal Panel 2 test, select the sample type (Para-Pak C\u0026amp;S or FecalSwab).\u003c\/li\u003e\n\u003cli\u003ePosition the cartridge on the instrument’s sample port. The cartridge will automatically move in and the test will start.\u003c\/li\u003e\n\u003cli\u003eAfter about an hour, view the comprehensive results.\u003c\/li\u003e\n\u003c\/ol\u003e\u003ch2\u003eDocuments\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/kithandbookandprotocol\/hb-3598-003-r3-qiastatdx-respi-panel-mini-0825-us\" target=\"_blank\" rel=\"noopener\"\u003eQIAstat-Dx Respiratory Panel Mini Instructions for Use\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/scientificdocument\/qiastatdx-rp-mini-an-lv-us\" target=\"_blank\" rel=\"noopener\"\u003eGuidelines for Laboratory Verification of Performance of QIAstat-Dx Respiratory Panel Mini\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/kithandbookandprotocol\/hb-3474-003-hb-r3-qiastatdx-respipanelplus-0825-us\" target=\"_blank\" rel=\"noopener\"\u003eQIAstat-Dx Respiratory Panel Plus Instructions for Use\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/scientificdocument\/qiastatdx-rp-plus-an-lv-us\" target=\"_blank\" rel=\"noopener\"\u003eGuidelines for Laboratory Verification of Performance of QIAstat-Dx Respiratory Panel Plus\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eOrdering Information\u003c\/h2\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eCat. no.\u003c\/th\u003e\n\u003cth\u003eProduct\u003c\/th\u003e\n\u003cth\u003eContents\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\u003ctr\u003e\n\u003ctd\u003e691218\u003c\/td\u003e\n\u003ctd\u003eQIAstat-Dx Respiratory Panel Mini\u003c\/td\u003e\n\u003ctd\u003e6 individually packaged cartridges containing all reagents needed for sample preparation and multiplex RT-PCR, plus internal control, including six transfer pipettes.\u003c\/td\u003e\n\u003c\/tr\u003e\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003e\u003cem\u003eQIAstat-Dx instruments and QIAstat-Dx panels are intended for in vitro diagnostic use.\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eFor up-to-date licensing information and product-specific disclaimers, see the respective QIAGEN kit instructions for use or user manual. QIAGEN instructions for use and user manuals are available at www.qiagen.com or can be requested from QIAGEN Technical Services (or your local distributor).\u003c\/em\u003e\u003c\/p\u003e","brand":"QIAGEN","offers":[{"title":"Default Title","offer_id":46798468055119,"sku":"691218","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/1_5_WebFullSizeImage_42c9b1b2-52c0-425f-826d-7ffb943b4ac4.jpg?v=1789653386"},{"product_id":"qiagen-qiastat-dx-gastrointestinal-panel-2-691413","title":"QIAstat-Dx Gastrointestinal Panel 2","description":"\u003cp\u003e\u003cstrong\u003eQIAstat-Dx Gastrointestinal Panel 2\u003c\/strong\u003e – Qualitative test to analyze 22 most common pathogens causing gastrointestinal infections, including differentiation of Shiga-like toxin producing E. coli (STEC) stx1 and stx2 .\u003c\/p\u003e\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth colspan=\"4\"\u003eQIAstat-Dx Gastrointestinal Panel 2 – 23 pathogens, corresponding to 22 bacterial, \u003cem\u003eviral and parasitic pathogens\u003c\/em\u003e\n\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth colspan=\"2\"\u003eBacteria\u003c\/th\u003e\n\u003cth\u003eViruses\u003c\/th\u003e\n\u003cth\u003eParasites\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003cp\u003e\u003cem\u003eCampylobacter (C. jejuni, C. upsaliensis, C. coli)\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eClostridium difficile\u003c\/em\u003e (toxin A\/B)\u003c\/p\u003e\n\u003cp\u003eEnteroaggregative \u003cem\u003eE. coli\u003c\/em\u003e (EAEC)\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eShigella\u003c\/em\u003e\/Enteroinvasive\u003cem\u003e E. coli\u003c\/em\u003e (EIEC)\u003c\/p\u003e\n\u003cp\u003eEnteropathogenic \u003cem\u003eE. coli\u003c\/em\u003e (EPEC)\u003c\/p\u003e\n\u003cp\u003eEnterotoxigenic \u003cem\u003eE. coli\u003c\/em\u003e (ETEC) \u003cem\u003elt\/st\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003ePlesiomonas shigelloides\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd\u003e\n\u003cp\u003e\u003cem\u003eSalmonella\u003c\/em\u003e spp.\u003c\/p\u003e\n\u003cp\u003eShiga-like toxin-producing \u003cem\u003eE. coli\u003c\/em\u003e (STEC) \u003cem\u003estx1\u003c\/em\u003e and \u003cem\u003estx2\u003c\/em\u003e (including specific identification of E. coli O157 serogroup within STEC)*\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eVibrio vulnificus\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eVibrio parahaemolyticus\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eVibrio cholerae\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eYersinia enterocolitica\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd\u003e\n\u003cp\u003eAdenovirus F40\/41\u003c\/p\u003e\n\u003cp\u003eAstrovirus\u003c\/p\u003e\n\u003cp\u003eNorovirus (GI, GII)\u003c\/p\u003e\n\u003cp\u003eRotavirus A\u003c\/p\u003e\n\u003cp\u003eSapovirus (GI, GII, GIV, GV)\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd\u003e\n\u003cp\u003e\u003cem\u003eCryptosporidium\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eCyclospora cayetanensis\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eEntamoeba histolytica\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eGiardia lamblia\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003e*The \u003cem\u003estx1\u003c\/em\u003e and \u003cem\u003estx2\u003c\/em\u003e toxin genes of STEC are reported separately by the QIAstat-Dx Gastrointestinal Panel 2.\u003c\/p\u003e\u003cp\u003e6 individually packaged cartridges containing all reagents needed for sample preparation and multiplex real-time RT-PCR, plus internal control, including six transfer pipettes.\u003c\/p\u003e\u003ch2\u003eFeatures\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eIntuitive workflow with minimal hands-on time\u003c\/li\u003e\n\u003cli\u003eUses real-time PCR to deliver comprehensive results in about an hour\u003c\/li\u003e\n\u003cli\u003eEasily view Ct values and amplification curves for all detected pathogens\u003c\/li\u003e\n\u003cli\u003eNo precision pipetting required and unique direct swab protocol for input into the cartridge\u003c\/li\u003e\n\u003cli\u003eQIAsphere-connected for real-time updates, proactive remote service and custom epidemiology reports\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003ePrinciple\u003c\/h2\u003e\u003cp\u003eThe QIAstat-Dx Analyzers 1.0 and 2.0, combined with QIAstat-Dx assay cartridges, use real-time PCR to detect pathogen nucleic acids in human biological samples. The cartridges are designed as closed systems containing the necessary reagents for automated sample processing, following a simple sample preparation and loading step.  Detected real-time amplification signals are interpreted by the integrated software and are reported via an intuitive user interface.\u003c\/p\u003e\u003ch2\u003eProcedure\u003c\/h2\u003e\u003cp\u003eSetting up and running a QIAstat-Dx test requires minimal hands-on time and just a few simple steps. \u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003eAdd the patient sample to the main port of the QIAstat-Dx cartridge using the plastic pipette provided. For our respiratory panels, you can alternatively apply the sample with a dry swab. This step is fast and easy to perform and requires no precision pipetting.\u003c\/li\u003e\n\u003cli\u003ePress the Run Test button on the QIAstat-Dx touch screen and scan the sample ID barcode.\u003c\/li\u003e\n\u003cli\u003eScan the barcode of the cartridge you’re using.\u003c\/li\u003e\n\u003cli\u003ePosition the cartridge on the instrument’s sample port. The cartridge will automatically move in and the test will start.\u003c\/li\u003e\n\u003cli\u003eAfter about an hour, view the comprehensive results.\u003c\/li\u003e\n\u003c\/ol\u003e\u003ch2\u003eDocuments\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/gb\/resources\/kithandbookandprotocol\/hb-3462-002-ivdr-r1-qiastat-dx-gi-panel-2-1124-ce-row\" target=\"_blank\" rel=\"noopener\"\u003eQIAstat-Dx Gastrointestinal Panel 2 Instructions for Use (IVDR)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/gb\/resources\/scientificdocument\/qiastatdx-gi2-ce-ivdr-an-lv-row\" target=\"_blank\" rel=\"noopener\"\u003eGuidelines for Laboratory Verification of Performance of QIAstat-Dx Gastrointestinal Panel 2 (IVDR)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/gb\/resources\/scientificdocument\/prom-21582-001-an-qiastat-dx-gi2-panel-verification-0922-row\" target=\"_blank\" rel=\"noopener\"\u003eGuidelines for Laboratory Verification of Performance of the QIAstat-Dx Gastrointestinal Panel 2\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eOrdering Information\u003c\/h2\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eCat. no.\u003c\/th\u003e\n\u003cth\u003eProduct\u003c\/th\u003e\n\u003cth\u003eContents\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\u003ctr\u003e\n\u003ctd\u003e691413\u003c\/td\u003e\n\u003ctd\u003eQIAstat-Dx Gastrointestinal Panel 2\u003c\/td\u003e\n\u003ctd\u003e6 individually packaged cartridges containing all reagents needed for sample preparation and multiplex real-time RT-PCR, plus internal control, including six transfer pipettes.\u003c\/td\u003e\n\u003c\/tr\u003e\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003e\u003cem\u003eThe QIAstat-Dx instruments and QIAstat-Dx panels are intended for in vitro diagnostic use. \u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eFor up-to-date licensing information and product-specific disclaimers, see the respective QIAGEN kit instructions for use or user manual. QIAGEN instructions for use and user manuals are available at www.qiagen.com or can be requested from QIAGEN Technical Services (or your local distributor). \u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eProduct availability may differ from country to country based on regulations and approvals. Contact your country representative for further details.\u003c\/em\u003e\u003c\/p\u003e","brand":"QIAGEN","offers":[{"title":"Default Title","offer_id":46798468087887,"sku":"691413","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/1_5_WebFullSizeImage_35120cb0-6c15-4b1c-bb29-96f9af9f227d.jpg?v=1789653387"},{"product_id":"qiagen-qiastat-dx-gastrointestinal-panel-2-mini-691424","title":"QIAstat-Dx Gastrointestinal Panel 2 Mini","description":"\u003cp\u003e\u003cstrong\u003eQIAstat-Dx Gastrointestinal Panel 2 Mini B\u0026amp;V\u003c\/strong\u003e – FDA-cleared test to analyze 4 bacterial and 1 viral target for common pathogens causing gastrointestinal symptoms using preserved stool samples (Para-Pak C\u0026amp;S and FecalSwab). This is our targeted seasonal panel, ideal for outpatient testing.\u003c\/p\u003e\u003ctable\u003e\n\u003ccaption\u003e\n\u003cstrong\u003eQIAstat-Dx GI Panel 2 Mini B\u0026amp;V\u003c\/strong\u003e – 5 bacterial and viral targets\u003c\/caption\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003ctd\u003eBacteria\u003c\/td\u003e\n\u003ctd\u003eViruses\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cem\u003eCampylobacter\u003c\/em\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cem\u003eSalmonella \u003c\/em\u003e\u003c\/li\u003e\n\u003cli\u003eShiga-like toxin\u003cem\u003e E. coli \u003c\/em\u003e(STEC)\u003c\/li\u003e\n\u003cli\u003e\u003cem\u003eShigella\u003c\/em\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/td\u003e\n\u003ctd\u003e\n\u003cul\u003e\n\u003cli\u003eNorovirus\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003eThe QIAstat-Dx GI Panel 2 Mini B\u0026amp;V is available for use on the QIAstat-Dx Analyzer 2.0 and the QIAstat-Dx Rise.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eQIAstat-Dx Gastrointestinal Panel 2 Mini B\u003c\/strong\u003e – FDA-cleared test to analyze 5 bacterial targets for common pathogens causing gastrointestinal symptoms using preserved stool samples (Para-Pak C\u0026amp;S and FecalSwab). This is our targeted panel, ideal for outpatient testing.\u003c\/p\u003e\u003ctable\u003e\n\u003ccaption\u003e\n\u003cstrong\u003eQIAstat-Dx GI Panel 2 Mini B\u003c\/strong\u003e – 5 bacterial targets\u003c\/caption\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eBacteria \u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cem\u003eCampylobacter\u003c\/em\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cem\u003eSalmonella\u003c\/em\u003e\u003c\/li\u003e\n\u003cli\u003eShiga-like toxin\u003cem\u003e E. coli \u003c\/em\u003e(STEC)\u003c\/li\u003e\n\u003cli\u003e\u003cem\u003eShigella\u003c\/em\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cem\u003eYersinia enterocolitica\u003c\/em\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eThe QIAstat-Dx GI Panel 2 Mini B is available for use on the QIAstat-Dx Analyzer 2.0 and the QIAstat-Dx Rise.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003e6 individually packaged cartridges containing all reagents needed for sample preparation and multiplex RT-PCR, plus internal control, including six transfer pipettes.\u003c\/p\u003e\u003ch2\u003eFeatures\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eIntuitive workflow with minimal hands-on time\u003c\/li\u003e\n\u003cli\u003eUses RT-PCR to deliver comprehensive results in about an hour\u003c\/li\u003e\n\u003cli\u003eProvides Ct values and amplification curves for all detected pathogens directly on the instrument touchscreen\u003c\/li\u003e\n\u003cli\u003eNo precision pipetting required\u003c\/li\u003e\n\u003cli\u003eQIAsphere-connected for real-time updates and custom epidemiology reports*\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003ePrinciple\u003c\/h2\u003e\u003cp\u003eThe QIAstat-Dx Analyzer 2.0, combined with QIAstat-Dx assay cartridges, use real-time PCR to detect pathogen nucleic acids in human biological samples. The QIAstat-Dx Analyzer 2.0 and cartridges are designed as closed systems that contain all necessary reagents, enabling hands-off sample preparation. Detected real-time amplification signals are interpreted by the integrated software and are reported via an intuitive user interface.\u003c\/p\u003e\u003ch2\u003eProcedure\u003c\/h2\u003e\u003cp\u003eSetting up and running a QIAstat-Dx test requires minimal hands-on time and just a few simple steps.\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003eAdd the patient sample to the main port of the QIAstat-Dx cartridge using the plastic pipette provided. This step is fast and easy to perform and requires no precision pipetting.\u003c\/li\u003e\n\u003cli\u003ePress the Run Test button on the QIAstat-Dx touch screen and scan the sample ID barcode.\u003c\/li\u003e\n\u003cli\u003eScan the barcode of the cartridge you’re using.\u003c\/li\u003e\n\u003cli\u003eFor our QIAstat-Dx Gastrointestinal Panel 2 test, select the sample type (Para-Pak C\u0026amp;S or FecalSwab).\u003c\/li\u003e\n\u003cli\u003ePosition the cartridge on the instrument’s sample port. The cartridge will automatically move in and the test will start.\u003c\/li\u003e\n\u003cli\u003eAfter about an hour, view the comprehensive results.\u003c\/li\u003e\n\u003c\/ol\u003e\u003ch2\u003eDocuments\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/kithandbookandprotocol\/hb-3600-004_r4_qiastatdx_gi2_minib_0326_us\" target=\"_blank\" rel=\"noopener\"\u003eQIAstat-Dx GI Panel 2 Mini B Instructions for Use\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/kithandbookandprotocol\/hb-3601-004_r4_qiastatdx_gi2_minibv_0326_us\" target=\"_blank\" rel=\"noopener\"\u003eQIAstat-Dx GI Panel 2 Mini B\u0026amp;V Instructions for Use\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/scientificdocument\/qiastatdx-gi2-mini-b-an-lv-us\" target=\"_blank\" rel=\"noopener\"\u003eGuidelines for Laboratory Verification of Performance of QIAstat-Dx GI Panel 2 Mini B\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/scientificdocument\/qiastatdx-gi2-mini-bv-an-lv-us\" target=\"_blank\" rel=\"noopener\"\u003eGuidelines for Laboratory Verification of Performance of QIAstat-Dx GI Panel 2 Mini B\u0026amp;V\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eOrdering Information\u003c\/h2\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eCat. no.\u003c\/th\u003e\n\u003cth\u003eProduct\u003c\/th\u003e\n\u003cth\u003eContents\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e691424\u003c\/td\u003e\n\u003ctd\u003eQIAstat-Dx GI Panel 2 Mini B\u0026amp;V\u003c\/td\u003e\n\u003ctd\u003e6 individually packaged cartridges containing all reagents needed for sample preparation and multiplex RT-PCR, plus internal control, including six transfer pipettes.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e691423\u003c\/td\u003e\n\u003ctd\u003eQIAstat-Dx GI Panel 2 Mini B\u003c\/td\u003e\n\u003ctd\u003e6 individually packaged cartridges containing all reagents needed for sample preparation and multiplex RT-real time PCR, plus internal control, including six transfer pipettes.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003e\u003cem\u003eQIAstat-Dx instruments and QIAstat-Dx panels are intended for in vitro diagnostic use.\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eFor up-to-date licensing information and product-specific disclaimers, see the respective QIAGEN kit instructions for use or user manual. QIAGEN instructions for use and user manuals are available at www.qiagen.com or can be requested from QIAGEN Technical Services (or your local distributor).\u003c\/em\u003e\u003c\/p\u003e","brand":"QIAGEN","offers":[{"title":"Mini B\u0026V","offer_id":46798468546639,"sku":"691424","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Mini B","offer_id":46798468579407,"sku":"691423","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/1_5_WebFullSizeImage_fdd4574f-76d4-4f4e-a152-f196f7b99716.jpg?v=1789653392"},{"product_id":"qiagen-qiastat-dx-meningitis-encephalitis-panel-ivdr-691612","title":"QIAstat-Dx Meningitis\/Encephalitis Panel (IVDR)","description":"\u003cp\u003e\u003cstrong\u003eQIAstat-Dx Meningitis\/Encephalitis Panel\u003c\/strong\u003e – Qualitative test to analyze 16 of the most common targets causing central nervous system infections (meningitis and encephalitis).\u003c\/p\u003e\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth colspan=\"3\"\u003eQIAstat-Dx Meningitis\/Encephalitis Panel – 16 bacterial, viral and fungal targets\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eBacteria\u003c\/th\u003e\n\u003cth\u003eViruses\u003c\/th\u003e\n\u003cth\u003eFungi\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003cp\u003e\u003cem\u003eEscherichia coli\u003c\/em\u003e K1\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eHaemophilus influenzae\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eListeria monocytogenes\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eNeisseria meningitidis\u003c\/em\u003e (encapsulated)\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eStreptococcus agalactiae\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eStreptococcus pneumoniae\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eMycoplasma pneumoniae\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eStreptococcus pyogenes\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd\u003e\n\u003cp\u003eCytomegalovirus\u003c\/p\u003e\n\u003cp\u003eEnterovirus\u003c\/p\u003e\n\u003cp\u003eHerpes simplex virus 1\u003c\/p\u003e\n\u003cp\u003eHerpes simplex virus 2\u003c\/p\u003e\n\u003cp\u003eHuman herpes virus 6\u003c\/p\u003e\n\u003cp\u003eHuman parechovirus\u003c\/p\u003e\n\u003cp\u003eVaricella zoster virus\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd\u003e\n\u003cem\u003eCryptococcus neoformans\/gattii\u003c\/em\u003e *\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003e*\u003cem\u003eCryptococcus neoformans\/Cryptococcus gattii\u003c\/em\u003e are both detected, but not differentiated, with the QIAstat-Dx Meningitis\/Encephalitis Panel.\u003c\/p\u003e\u003cp\u003e6 individually packaged cartridges containing all reagents needed for sample preparation and multiplex real-time RT-PCR, plus internal control, including six transfer pipettes.\u003c\/p\u003e\u003ch2\u003eFeatures\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eIntuitive workflow with minimal hands-on time\u003c\/li\u003e\n\u003cli\u003eUses real-time PCR to deliver comprehensive results in about an hour\u003c\/li\u003e\n\u003cli\u003eEasily view Ct values and amplification curves for all detected pathogens\u003c\/li\u003e\n\u003cli\u003eNo precision pipetting required and unique direct swab protocol for input into the cartridge\u003c\/li\u003e\n\u003cli\u003eQIAsphere-connected for real-time updates, proactive remote service and custom epidemiology reports\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003ePrinciple\u003c\/h2\u003e\u003cp\u003eThe QIAstat-Dx Analyzers 1.0 and 2.0, combined with QIAstat-Dx assay cartridges, use real-time PCR to detect pathogen nucleic acids in human biological samples. The cartridges are designed as closed systems containing the necessary reagents for automated sample processing, following a simple sample preparation and loading step.  Detected real-time amplification signals are interpreted by the integrated software and are reported via an intuitive user interface.\u003c\/p\u003e\u003ch2\u003eProcedure\u003c\/h2\u003e\u003cp\u003eSetting up and running a QIAstat-Dx test requires minimal hands-on time and just a few simple steps. \u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003eAdd the patient sample to the main port of the QIAstat-Dx cartridge using the plastic pipette provided. For our respiratory panels, you can alternatively apply the sample with a dry swab. This step is fast and easy to perform and requires no precision pipetting.\u003c\/li\u003e\n\u003cli\u003ePress the Run Test button on the QIAstat-Dx touch screen and scan the sample ID barcode.\u003c\/li\u003e\n\u003cli\u003eScan the barcode of the cartridge you’re using.\u003c\/li\u003e\n\u003cli\u003ePosition the cartridge on the instrument’s sample port. The cartridge will automatically move in and the test will start.\u003c\/li\u003e\n\u003cli\u003eAfter about an hour, view the comprehensive results.\u003c\/li\u003e\n\u003c\/ol\u003e\u003ch2\u003eDocuments\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/gb\/resources\/kithandbookandprotocol\/hb-3697-001-ivdr-qiastatdx-me-panel-0625-row\" target=\"_blank\" rel=\"noopener\"\u003eQIAstat-Dx Meningitis\/Encephalitis (ME) Panel Instructions for Use (IVDR)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/gb\/resources\/kithandbookandprotocol\/hb-3697-spr-001-qiastatdx-me-panel-ce-0725-row\" target=\"_blank\" rel=\"noopener\"\u003eQIAstat-Dx Meningitis\/Encephalitis (ME) Panel Summary of Safety and Performance\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/gb\/resources\/scientificdocument\/qiastatdx-me-ce-ivdr-an-lv-row\" target=\"_blank\" rel=\"noopener\"\u003eGuidelines for Laboratory Verification of Performance of QIAstat-Dx Meningitis\/Encephalitis (ME) Panel (IVDR)\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eOrdering Information\u003c\/h2\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eCat. no.\u003c\/th\u003e\n\u003cth\u003eProduct\u003c\/th\u003e\n\u003cth\u003eContents\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\u003ctr\u003e\n\u003ctd\u003e691612\u003c\/td\u003e\n\u003ctd\u003eQIAstat-Dx Meningitis\/Encephalitis Panel (IVDR)\u003c\/td\u003e\n\u003ctd\u003e6 individually packaged cartridges containing all reagents needed for sample preparation and multiplex real-time RT-PCR, plus internal control, including six transfer pipettes.\u003c\/td\u003e\n\u003c\/tr\u003e\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003e\u003cem\u003eThe QIAstat-Dx instruments and QIAstat-Dx panels are intended for in vitro diagnostic use. \u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eFor up-to-date licensing information and product-specific disclaimers, see the respective QIAGEN kit instructions for use or user manual. QIAGEN instructions for use and user manuals are available at www.qiagen.com or can be requested from QIAGEN Technical Services (or your local distributor). \u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eProduct availability may differ from country to country based on regulations and approvals. Contact your country representative for further details.\u003c\/em\u003e\u003c\/p\u003e","brand":"QIAGEN","offers":[{"title":"Default Title","offer_id":46798468513871,"sku":"691612","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/1_5_WebFullSizeImage_dcfce570-a320-4b43-8ac7-3358cf134dd3.jpg?v=1789653392"},{"product_id":"qiagen-qiastat-dx-viral-vesicular-panel-691731","title":"QIAstat-Dx Viral Vesicular Panel","description":"\u003cp\u003eThe QIAstat-Dx Analyzer, combined with QIAstat-Dx assay cartridges, uses real-time PCR to detect pathogen nucleic acids in human biological samples. The QIAstat-Dx Analyzer and cartridges are designed as a closed system that enables hands-off sample preparation followed by detection and identification of pathogen nucleic acids. Samples are inserted into a QIAstat-Dx cartridge, which contains all the reagents to isolate and amplify nucleic acids from the sample. Detected real-time amplification signals are interpreted by the integrated software and are reported via an intuitive user interface.\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003eAvailable panels utilize powerful QIAGEN sample and assay technologies, to deliver true Sample to Insight processing of even the most challenging samples.\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003e\u003cstrong\u003eQIAstat-Dx Viral Vesicular Panel:\u003c\/strong\u003e The QIAstat-Dx Viral Vesicular Panel can be used to detect viral nucleic acid from transport media by real-time RT-PCR. This multiplex PCR syndromic cartridge detects and differentiates 8 targets - mpox virus (MPXV) clade I*, MPXV clade II, orthopoxvirus (OPXV), herpes simplex virus (HSV) 1, HSV-2, human herpes virus 6, enterovirus and varicella zoster virus.\u003cbr\u003e \u003cbr\u003e*MPXV clade I does not detect Ib samples, these samples will give a positive orthopoxvirus (OPXV) result.\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003e\u003cstrong\u003eQIAstat-Dx Respiratory Panel:\u003c\/strong\u003e This version of our multiplex syndromic cartridge detects and differentiates 22 respiratory targets from nasopharyngeal swabs (NPS).\u003c\/p\u003e\u003cp\u003eSix individually packaged cartridges containing all reagents needed for sample preparation and multiplex real-time PCR plus internal control, including six transfer pipettes\u003c\/p\u003e\u003cp\u003e\u003cem\u003eFor research use only - not for use in diagnostic procedures.\u003c\/em\u003e\u003c\/p\u003e\u003ch2\u003eFeatures\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eIntuitive workflow with minimal hands-on time\u003c\/li\u003e\n\u003cli\u003eUses real-time PCR to deliver comprehensive results in about an hour\u003c\/li\u003e\n\u003cli\u003eEasily view Ct values and amplification curves for all detected pathogens\u003c\/li\u003e\n\u003cli\u003eNo precision pipetting required and unique direct swab protocol for input into the cartridge\u003c\/li\u003e\n\u003cli\u003eQIAsphere-connected for real-time updates, proactive remote service and custom epidemiology reports\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eDocuments\u003c\/h2\u003e\u003cul\u003e\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/gb\/resources\/kithandbookandprotocol\/hb-3633-001-r1-hb-qiastat-dx-viralvesicular-v2-0924-row\" target=\"_blank\" rel=\"noopener\"\u003eQIAstat-Dx Viral Vesicular Instructions for Use\u003c\/a\u003e\u003c\/li\u003e\u003c\/ul\u003e\u003ch2\u003eOrdering Information\u003c\/h2\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eCat. no.\u003c\/th\u003e\n\u003cth\u003eProduct\u003c\/th\u003e\n\u003cth\u003eContents\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\u003ctr\u003e\n\u003ctd\u003e691731\u003c\/td\u003e\n\u003ctd\u003eQIAstat-Dx Viral Vesicular Panel\u003c\/td\u003e\n\u003ctd\u003eSix individually packaged cartridges containing all reagents needed for sample preparation and multiplex real-time PCR plus internal control, including six transfer pipettes\u003c\/td\u003e\n\u003c\/tr\u003e\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003e\u003cem\u003eThe QIAstat-Dx Viral Vesicular Panel and QIAstat-Dx Respiratory Panel are for research use only. Not for use in diagnostic procedures. The QIAstat-Dx Viral Vesicular Panel and QIAstat-Dx Respiratory Panel are run on the QIAstat-Dx Analyzer.\u003c\/em\u003e\u003c\/p\u003e","brand":"QIAGEN","offers":[{"title":"Default Title","offer_id":46798468677711,"sku":"691731","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/1_5_WebFullSizeImage_ede18246-1275-48df-b9c8-af2ab5d89574.jpg?v=1789653398"},{"product_id":"qiagen-miseq-fgx-sequencing-system-for-forensic-genomics-15048976","title":"MiSeq FGx Sequencing System for Forensic Genomics","description":"\u003cp\u003eThe MiSeq FGx Sequencing System is the first and only next-generation sequencing (NGS) instrument designed, developed and validated for forensic genomics. Combining proven data quality with ease of use, the system is key to a unique, single-platform solution built on gold-standard NGS technology. Prepare and sequence libraries and analyze data in a single workflow designed to scale for a growing portfolio of applications, including new tools like Forensic Investigative Genetic Genealogy (FIGG). Dedicated reagent kits and matched analysis software empower answers for all human identification investigations.\u003c\/p\u003e\u003cp\u003eMiSeq FGx Sequencing System is a desktop NGS instrument with integrated software for run setup, results interpretation and reporting\u003c\/p\u003e\u003ch2\u003eFeatures\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eHigh-performance benchtop sequencer with intuitive touch‑screen and load-and-go reagents\u003c\/li\u003e\n\u003cli\u003eAdvanced capacity to process challenging DNA samples\u003c\/li\u003e\n\u003cli\u003eInterrogates hundreds of markers in a single workflow\u003c\/li\u003e\n\u003cli\u003eOptimized flexibility for human identification applications\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003ePerformance\u003c\/h2\u003e\u003cp\u003eThe MiSeq FGx System is integral to a validated workflow designed specifically for forensic laboratories. The system is fully supported with performance qualifications and available maintenance that align to requirements of a forensic laboratory. Building on the speed and accuracy of Illumina sequencing-by-synthesis (SBS) chemistry, the MiSeq FGx System brings the unprecedented focus of forensic genomics to NGS, granting criminal justice a powerful ally.\u003c\/p\u003e\n\u003cp\u003eSuperior analysis of complex DNA mixtures and degraded DNA \u003c\/p\u003e\n\u003cp\u003eIntegrated sequencing workflow consolidates library prep, sequencing, and analysis\u003c\/p\u003e\n\u003cp\u003eAdvanced capability with adjustable read lengths, dual run modes and two flow cells \u003c\/p\u003e\n\u003cp\u003eThe MiSeq FGx System is the first and only instrument to interrogate up to 96 combined SNP and STR libraries in a single run. The MiSeq FGx System preserves precious sample while demonstrating robust performance, developing more thorough, detailed DNA profiles from a wide range of sample types, biological molecules, and across the quality spectrum of high-quality genomic DNA (gDNA) to degraded, mixed and limited samples.\u003c\/p\u003e\n\u003cp\u003eTwo run modes promote a range of forensic genomics applications while retaining the flexibility to work in a research environment. Easily switch between two sequencing kits to tune output for the current application or sample batch size. Built on industry-leading Illumina SBS chemistry, the MiSeq FGx System meets strict performance requirements for comprehensive and conclusive results. Virtually eliminate context-specific errors, even within repetitive sequence regions or homopolymers and answer a wider range of questions in one targeted assay with multiplexing capability. An intuitive touchscreen interface simplifies instrument operation and the system monitors quality and performance metrics during a run. After sequencing, analysis starts automatically and completes in under one hour.\u003c\/p\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003e\u003cstrong\u003eFeature\u003c\/strong\u003e\u003c\/th\u003e\n\u003cth\u003e\u003cstrong\u003eDetails\u003c\/strong\u003e\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eThroughput\u003c\/td\u003e\n\u003ctd\u003e1–384 samples per run, depending on assay\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMaximum read length\u003c\/td\u003e\n\u003ctd\u003e2 x 300 bp, depending on assay\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eOutput (2 x 150 bp run)\u003c\/td\u003e\n\u003ctd\u003e≥ 5 Gb\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eReads passing filters\u003c\/td\u003e\n\u003ctd\u003e25 million\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eQ30 score (at read length of 2 x 150 bp)\u003c\/td\u003e\n\u003ctd\u003e≥ 80%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTotal overall accuracy \u003c\/td\u003e\n\u003ctd\u003e≥ 99.66%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTotal overall reproducibility\u003c\/td\u003e\n\u003ctd\u003e≥ 99.7%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBiomolecules that can be sequenced\u003c\/td\u003e\n\u003ctd\u003egDNA, RNA, mtDNA\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eModes\u003c\/td\u003e\n\u003ctd\u003eForensic (FGx) and Research Use Only (RUO)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePower requirements\u003c\/td\u003e\n\u003ctd\u003e100–240 V AC at 50\/60Hz, 10A, 400 W\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eRFID radio frequency\u003c\/td\u003e\n\u003ctd\u003e13.56 MHz\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eRFID power\u003c\/td\u003e\n\u003ctd\u003e100 mW\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eDimensions\u003c\/td\u003e\n\u003ctd\u003e68.6 cm × 56.5 cm × 52.3 cm (27 in × 22.2 in × 20.6 in)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWeight\u003c\/td\u003e\n\u003ctd\u003e54.5 kg (120 lbs)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003ch2\u003ePrinciple\u003c\/h2\u003e\u003cp\u003eCompared to size-based analysis of short tandem repeats (STRs) using capillary electrophoresis (CE), NGS detects the full spectrum of genetic variation in a DNA sample with a faster time to results than other technologies. Inherently sensitive, ForenSeq NGS technology goes beyond fragment size to identify underlying sequence variation. Comprehensive results are delivered quickly and clearly, displaying base-by-base sequences for easy interpretation with utmost confidence. Building on STR capabilities, NGS brings other advantages to modern forensic genomics, including analysis of nuclear single nucleotide polymorphisms (SNPs), mitochondrial DNA (mtDNA), messenger RNA (mRNA) and epigenetic markers, bolstering cases that require human identification while eliminating the need to weigh technical limitations against potentially informative data. Achieve superior results in a single sequencing run.\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003eThe MiSeq FGx System achieves exceptional data quality by employing a proprietary, reversible terminator‑based method that detects single bases as they are incorporated into massively parallel DNA strands. Fluorescent terminator dyes are imaged as each deoxynucleotide triphosphate (dNTP) is added and then cleaved to allow incorporation of the next base. With all four reversible, terminator-bound dNTPs present at each sequencing cycle, natural competition among bases minimizes incorporation bias. The software makes base calls directly from signal intensity measurements during each incorporation cycle, reducing raw error rates compared to other technologies. The result is highly accurate, base-by-base sequencing that minimizes sequence context‑specific errors, even within repetitive sequence regions or homopolymers.\u003c\/p\u003e\u003ch2\u003eProcedure\u003c\/h2\u003e\u003cp\u003eLibraries sequenced on the MiSeq FGx System follow the same core NGS workflow: library prep, sequencing and analysis. The first step uses a library prep kit to add primers to genomic DNA (gDNA), mtDNA or mRNA extracted from forensic samples for simultaneous capture and amplification of hundreds of target regions, generating dual-indexed libraries ready for sequencing. After library prep, load-and-go reagents streamline run setup. Simply thaw the prefilled reagent cartridge, add libraries to the cartridge, and insert the cartridge into the instrument. The system software accepts run parameters and starts sequencing with the push of a button.\u003c\/p\u003e\u003ch2\u003eApplications\u003c\/h2\u003e\u003cp\u003eThe MiSeq FGx System enables capabilities across all biological molecules and a growing number of applications, including both short- and long-range kinship analysis. Adjustable read lengths, flow cell options and choice of run modes allow unprecedented flexibility for matching data output to an ever-increasing range of human identification needs. The MiSeq FGx System delivers an enhanced capacity to analyze degraded DNA, low-quantity DNA, complex DNA mixtures and other challenging samples that can complicate or derail an investigation. Small amplicon sizes are well suited for interrogation of degraded DNA, while large numbers of markers—including many that are highly polymorphic—improve system ability to discern low-level minor components that CE might not detect. Additionally, one sequencing run interrogates hundreds of forensically relevant genetic markers, eliminating the need to choose between fragment length‑based STR kits or otherwise make trade-offs to accommodate challenging samples.\u003c\/p\u003e\u003ch2\u003eSoftware\u003c\/h2\u003e\u003cp\u003eThe MiSeq FGx System features an intuitive touch-screen interface that provides step-by-step guidance through each stage of a sequencing run, from consumables loading through run configuration and monitoring. Onboard cluster generation and automated analysis initialization minimize hands-on time. Complementing the onboard software, the system integrates with Universal Analysis Software (UAS), a fully optimized analysis platform that delivers a powerful suite of forensic‑tuned capabilities, including automatic detection of mixed samples, generation of population statistics, database‑compatible reports, and more. UAS ships preinstalled on a dedicated server that is independent of the instrument, eliminating the need for auxiliary hardware and computing resources and maintaining the minimal instrument footprint of only 0.4 square meters. \u003c\/p\u003e\u003ch2\u003eDocuments\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/validationandtechnicaldocument\/qpro-6229-ti-hid-miseq-fgxsequencingsystem-0424-ww\" target=\"_blank\" rel=\"noopener\"\u003eMiSeq FGx Sequencing System\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/ebook.qiagen.com\/books\/muhf\/\" target=\"_blank\" rel=\"noopener\"\u003eIntegrated workflows for sexual assault analysis: Reliable forensic workflows for complex sexual assault evidence\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/brochureandguide\/prom-19028-001-1125732-fly-hid-ngs-0821-ww\" target=\"_blank\" rel=\"noopener\"\u003eA new horizon of human identification possibilities with NGS\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/brochureandguide\/qpro-5802-fly-hid-nippt-0324-ww\" target=\"_blank\" rel=\"noopener\"\u003ePaternity Doubts Erased\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/brochureandguide\/qpro-11254-bro-hid-ngs-in-hid-0825-ww\" target=\"_blank\" rel=\"noopener\"\u003eReimagining Human Identification\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/validationandtechnicaldocument\/qpro-6230-ti-hid-forenseq-dnasignatureprepkit-0424-ww\" target=\"_blank\" rel=\"noopener\"\u003eForenSeq DNA Signature Prep Kit\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/validationandtechnicaldocument\/qpro-6310-ti-hid-kintelligence-ht-kit-0324-ww\" target=\"_blank\" rel=\"noopener\"\u003eForenSeq Kintelligence HT Kit\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/validationandtechnicaldocument\/qpro-6696-ti-hid-forenseq-kintelligencekit-0424-ww\" target=\"_blank\" rel=\"noopener\"\u003eForenSeq Kintelligence Kit\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eOrdering Information\u003c\/h2\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eCat. no.\u003c\/th\u003e\n\u003cth\u003eProduct\u003c\/th\u003e\n\u003cth\u003eContents\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\u003ctr\u003e\n\u003ctd\u003e15048976\u003c\/td\u003e\n\u003ctd\u003eMiSeq FGx Sequencing System\u003c\/td\u003e\n\u003ctd\u003eMiSeq FGx Sequencing System is a desktop NGS instrument with integrated software for run setup, results interpretation and reporting\u003c\/td\u003e\n\u003c\/tr\u003e\u003c\/tbody\u003e\n\u003c\/table\u003e","brand":"QIAGEN","offers":[{"title":"Default Title","offer_id":46798468710479,"sku":"15048976","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/1_5_WebFullSizeImage_532b6a71-90e2-4aa7-82af-f5669f61acc2.jpg?v=1789653399"},{"product_id":"qiagen-miseq-fgx-sequencing-reagent-kits-15066817","title":"Verogen MiSeq FGx Sequencing Reagent Kits","description":"\u003cp\u003eGenerate high-quality sequencing data with MiSeq FGx Sequencing Reagents. These pre-filled, ready-to-use cartridges leverage gold-standard sequencing-by-synthesis (SBS) chemistry to support a range of laboratory throughput requirements. MiSeq FGx Sequencing Reagents support both Forensic Genomics and Research Use Only modes on the MiSeq FGx Sequencing System to simplify inventory and ordering for all applications.\u003c\/p\u003e\u003ch2\u003eFeatures\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eAdjustable read length for flexibility across a broad range of applications\u003c\/li\u003e\n\u003cli\u003eFlexible kit sizes for deep sequencing or faster turnaround\u003c\/li\u003e\n\u003cli\u003ePre-filled cartridges with intuitive user workflow\u003c\/li\u003e\n\u003cli\u003eOptimized chemistry delivers exceptional data quality\u003c\/li\u003e\n\u003cli\u003eQuality controlled to meet forensic standards\u003c\/li\u003e\n\u003cli\u003eExtended shelf life supports long-term forensic projects\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003ePerformance\u003c\/h2\u003e\u003cp\u003eThe MiSeq FGx Reagent Kit has been optimized for sequencing forensic samples and delivers high-quality performance for a range of forensic applications. The extended read lengths enable deep sequencing of STRs, mtDNA and SNPs. The MiSeq FGx Reagent Micro Kit is purpose-built for lower throughput and faster sequencing time, while delivering equivalent quality. Both kit sizes are quality controlled to meet the high standards expected from forensic laboratories. The MiSeq FGx Sequencing Reagents are integral to the MiSeq FGx Sequencing System and support analysis of libraries across the range of Verogen NGS kits.\u003c\/p\u003e\u003ch2\u003ePrinciple\u003c\/h2\u003e\u003cp\u003eThe MiSeq FGx System achieves exceptional data quality by employing a proprietary, reversible terminator‑based method that detects single bases as they are incorporated into massively parallel DNA strands. Fluorescent terminator dyes are imaged as each deoxynucleotide triphosphate (dNTP) is added and then cleaved to allow incorporation of the next base. With all four reversible, terminator-bound dNTPs present at each sequencing cycle, natural competition among bases minimizes incorporation bias.\u003c\/p\u003e\n\u003cp\u003eThe MiSeq FGx Reagent Micro Kit and the MiSeq FGx Reagent Kit are identical in manufacture. With both kits, the best-in-class sequencing-by-synthesis (SBS) technology remains unaltered. The only difference is the surface area of the flow cell available for imaging. The MiSeq FGx System images the micro flow cell at approximately 35% of the standard flow cell area for a total output of 5 million reads.\u003c\/p\u003e\u003ch2\u003eProcedure\u003c\/h2\u003e\u003cp\u003eThe first sequencing step of the MiSeq FGx Sequencing System uses a library prep kit to add primers to genomic DNA (gDNA), mtDNA, or mRNA extracted from forensic samples for simultaneous capture and amplification of hundreds of target regions, generating dual-indexed libraries ready for sequencing. After library prep, load-and-go MiSeq FGx Sequencing Reagents streamline run setup. Simply thaw the prefilled reagent cartridge, add libraries to the cartridge, and insert the cartridge into the instrument. The system software accepts run parameters and starts sequencing with the push of a button.\u003c\/p\u003e\u003ch2\u003eApplications\u003c\/h2\u003e\u003cp\u003eThe MiSeq FGx System and the MiSeq FGx Reagent kits enable capabilities across all biological molecules and a growing number of forensic applications, including both short- and long-range kinship analysis. Adjustable read lengths, flow cell options and choice of run modes allow unprecedented flexibility for matching data output to an ever-increasing range of human identification needs. This gold-standard sequencing chemistry coupled with the trusted ForenSeq workflow and Universal Analysis Software can enable laboratories of all sizes and throughputs to adopt and operationalize NGS forensic workflows.\u003c\/p\u003e\u003ch2\u003eSoftware\u003c\/h2\u003e\u003cp\u003eThe MiSeq FGx System features an intuitive touch-screen interface that provides step-by-step guidance through each stage of a sequencing run. Complementing the onboard software, the system integrates with Universal Analysis Software (UAS), a fully optimized analysis platform that delivers a powerful suite of forensic‑tuned capabilities, including automatic detection of mixed samples, generation of population statistics, database‑compatible reports, and more.\u003c\/p\u003e\u003ch2\u003eDocuments\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/validationandtechnicaldocument\/qpro-6229-ti-hid-miseq-fgxsequencingsystem-0424-ww\" target=\"_blank\" rel=\"noopener\"\u003eMiSeq FGx Sequencing System\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/usermanual\/miseq-fgx-system-reference-guide-vd2018006-f-2\" target=\"_blank\" rel=\"noopener\"\u003eMiSeq FGx Sequencing System Reference Guide\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/ebook.qiagen.com\/books\/muhf\/\" target=\"_blank\" rel=\"noopener\"\u003eIntegrated workflows for sexual assault analysis: Reliable forensic workflows for complex sexual assault evidence\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/brochureandguide\/prom-19028-001-1125732-fly-hid-ngs-0821-ww\" target=\"_blank\" rel=\"noopener\"\u003eA new horizon of human identification possibilities with NGS\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/brochureandguide\/qpro-11254-bro-hid-ngs-in-hid-0825-ww\" target=\"_blank\" rel=\"noopener\"\u003eReimagining Human Identification\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/validationandtechnicaldocument\/qpro-6230-ti-hid-forenseq-dnasignatureprepkit-0424-ww\" target=\"_blank\" rel=\"noopener\"\u003eForenSeq DNA Signature Prep Kit\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/validationandtechnicaldocument\/qpro-6234-ti-hid-forenseq-imagenkit-1224-ww\" target=\"_blank\" rel=\"noopener\"\u003eForenSeq Imagen Kit\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/validationandtechnicaldocument\/qpro-6310-ti-hid-kintelligence-ht-kit-0324-ww\" target=\"_blank\" rel=\"noopener\"\u003eForenSeq Kintelligence HT Kit\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eOrdering Information\u003c\/h2\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eCat. no.\u003c\/th\u003e\n\u003cth\u003eProduct\u003c\/th\u003e\n\u003cth\u003eContents\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e15066817\u003c\/td\u003e\n\u003ctd\u003eVerogen MiSeq FGx Reagent Kit\u003c\/td\u003e\n\u003ctd\u003eSupports up to 12.5 million paired-end reads for deep sequencing or high-throughput sample processing\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e20021681\u003c\/td\u003e\n\u003ctd\u003eVerogen MiSeq FGx Reagent Micro Kit\u003c\/td\u003e\n\u003ctd\u003eSupports up to 5 million paired-end reads for small batch sizes and faster turnaround times\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003e\u003cem\u003eThe Verogen MiSeq FGx Sequencing Reagents is intended for molecular biology applications in forensic, human identity, and paternity testing. This product is not intended for diagnosis, prevention, or treatment of a disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"QIAGEN","offers":[{"title":"Reagent Kit","offer_id":46798468808783,"sku":"15066817","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Reagent Micro Kit","offer_id":46798468841551,"sku":"20021681","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/1_5_WebFullSizeImage_c2d502c2-ed46-4ecb-b0d3-2471fdb169f1.jpg?v=1789653404"},{"product_id":"qiagen-forenseq-signature-plus-kit-v16000213","title":"ForenSeq Signature Plus Kit","description":"\u003cp\u003eGenerate more comprehensive DNA profiles for up to 96 DNA samples with fewer than 2 hours of hands on time using our simple, plate-based workflow. The ForenSeq Signature Plus Kit is the next generation of the ForenSeq DNA Signature Prep Kit and introduces a new positive amplification control and UDI plate. All other components of the kit remain unchanged. The ForenSeq DNA Signature Prep Kit was the first next-generation sequencing (NGS)-based short-tandem repeat (STR) sequencing chemistry approved for upload to the National DNA Index System (NDIS) for casework. The ForenSeq DNA Signature Prep Kit is being retired due to a finite source of the positive amplification control material.\u003c\/p\u003e\n\u003cp\u003eThe ForenSeq Signature Plus Kit combines more than 200 markers, including autosomal, X- and Y-STRs, identity-informative, phenotype-informative and biogeographical ancestry-informative SNPs into a single, streamlined workflow, eliminating the need to run multiple STR tests. The easy, integrated workflow maximizes laboratory efficiency by simplifying training programs, validation procedures, proficiency testing and other quality assurance\/quality control measures required by external certification and accreditation programs. The solution is backwards compatible with current CE allele calling.\u003c\/p\u003e\u003ch2\u003eFeatures\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eInterrogate 200 genetic markers using a single streamlined workflow\u003c\/li\u003e\n\u003cli\u003eUDI plate for easier or automated transfer\u003c\/li\u003e\n\u003cli\u003eMultiplexing capability further boosts operational efficiency\u003c\/li\u003e\n\u003cli\u003eSuperior analysis of challenging and severely degraded samples\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003ePerformance\u003c\/h2\u003e\u003cp\u003eThe ForenSeq Signature Plus Kit is part of a complete, end-to-end massively parallel sequencing solution specifically designed for use in forensic genomics applications. The ForenSeq Signature Plus Kit allows your lab to prepare up to 96 DNA samples for Illumina next-generation sequencing (NGS) with a simple plate-based workflow.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eEliminate the need for multiple STR kits\u003c\/li\u003e\n\u003cli\u003eThe wider range of SNPs provides information not available with other technology\u003c\/li\u003e\n\u003cli\u003eObtain highly discriminating data from less than 100 pg of degraded or complex DNA\u003c\/li\u003e\n\u003cli\u003ePrepare up to 96 libraries simultaneously using an UDI plate and simple plate-based format\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThe ForenSeq Signature Plus Kit consolidates all autosomal short tandem repeat (STR) markers currently used around the world for casework and criminal DNA databasing into a single, streamlined workflow, eliminating the need to run multiple STR tests. In addition to autosomal, X-, and Y-STRs, the ForenSeq Signature Plus Kit offers marker sets not routinely available with traditional capillary electrophoresis (CE) methods. These include a dense set of identity-informative single nucleotide polymorphisms (iiSNPs) that are informative for source attribution, phenotypic-informative SNPs (piSNPs) that provide estimates of eye color (blue, intermediate, brown) and hair color (brown, red, black, blond), and biogeographical ancestry-informative SNPs (aiSNPs). These can be critical in generating investigative leads from “no suspect” cases that may have otherwise gone cold.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eForensic loci covered with the ForenSeq Signature Plus Kit\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eFeature\u003c\/th\u003e\n\u003cth\u003eNumber of markers\u003c\/th\u003e\n\u003cth\u003eAmplicon size (bp)\u003c\/th\u003e\n\u003cth\u003eDPMA\u003c\/th\u003e\n\u003cth\u003eDPMB\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eGlobal autosoma STRs\u003c\/td\u003e\n\u003ctd\u003e27\u003c\/td\u003e\n\u003ctd\u003e61–467\u003c\/td\u003e\n\u003ctd\u003eYes\u003c\/td\u003e\n\u003ctd\u003eYes\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eY-STRs\u003c\/td\u003e\n\u003ctd\u003e24\u003c\/td\u003e\n\u003ctd\u003e119–390\u003c\/td\u003e\n\u003ctd\u003eYes\u003c\/td\u003e\n\u003ctd\u003eYes\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eX-STRs\u003c\/td\u003e\n\u003ctd\u003e7\u003c\/td\u003e\n\u003ctd\u003e157–462\u003c\/td\u003e\n\u003ctd\u003eYes\u003c\/td\u003e\n\u003ctd\u003eYes\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eIdentity SNPs\u003c\/td\u003e\n\u003ctd\u003e94\u003c\/td\u003e\n\u003ctd\u003e63–261\u003c\/td\u003e\n\u003ctd\u003eYes\u003c\/td\u003e\n\u003ctd\u003eYes\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePhenotypic SNPs\u003c\/td\u003e\n\u003ctd\u003e22\u003c\/td\u003e\n\u003ctd\u003e73–227\u003c\/td\u003e\n\u003ctd\u003eNo\u003c\/td\u003e\n\u003ctd\u003eYes\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBiogeographical ancestry SNPs\u003c\/td\u003e\n\u003ctd\u003e56\u003c\/td\u003e\n\u003ctd\u003e67–200\u003c\/td\u003e\n\u003ctd\u003eNo\u003c\/td\u003e\n\u003ctd\u003eYes\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eIn a single reaction, Primer Mix A (DPMA) enables testing of all autosomal, X-, and Y-chromosome STR targets and the full set of iiSNPs. Primer Mix B (DPMB) includes the aiSNPs and piSNPs.\u003c\/p\u003e\n\u003cp\u003eThe ForenSeq Signature Plus Kit includes:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eDNA Primer Mix A: Contains primer pairs for 58 STRs (including 27 autosomal STRs, 7 X, and 24 Y haplotype markers) and 94 iiSNPs\u003c\/li\u003e\n\u003cli\u003eDNA Primer Mix B: Contains all markers in DNA Primer Mix A, plus primer pairs for 56 biogeographical aiSNPs and 22 piSNPs (2 aiSNPs are also used for phenotype estimation)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eMost SNPs included in the ForenSeq Signature Plus Kit contain amplicon sizes ≤125 bp, making them extremely well-suited for analysis of degraded DNA or even highly inhibited DNA extracts. The ForenSeq Signature Plus Kit also displays an improved ability to detect low-level minor components in mixtures that may otherwise go undetected with conventional STR and CE analysis. This increased power is due to the large number of markers included in the kit, many of which are highly polymorphic, coupled with the inherent sensitivity of the MiSeq FGx instrument.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSpecifications of the ForenSeq Signature Plus Kit\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eFeature\u003c\/th\u003e\n\u003cth\u003eDetails\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eSample types\u003c\/td\u003e\n\u003ctd\u003egDNA, buccal swabs, FTA card\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eRecommended input for human gDNA per sample\u003c\/td\u003e\n\u003ctd\u003e1 ng\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eRecommended input for FTA card punch per sample\u003c\/td\u003e\n\u003ctd\u003e1.2 mm\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMultiplexing capacity per run\u003c\/td\u003e\n\u003ctd\u003e8–96 samples\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eShort amplicon detection\u003c\/td\u003e\n\u003ctd\u003e≥65 bp\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLocus multiplexing\u003c\/td\u003e\n\u003ctd\u003eSimultaneous analysis of about 200 genetic markers\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTotal library prep time\u003c\/td\u003e\n\u003ctd\u003e7 hours and 15 minutes\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eHands-on times\u003c\/td\u003e\n\u003ctd\u003e1 hour and 45 minutes\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTotal sequencing time\u003c\/td\u003e\n\u003ctd\u003eAbout 28 hours with the MiSeq FGx Reagent Kit; about 22 hours with the MiSeq FGx Reagent Micro Kit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003ch2\u003ePrinciple\u003c\/h2\u003e\u003cp\u003eThe ForenSeq Signature Plus Kit is part of a fully integrated, sample-to-answer solution, including library preparation, DNA sequencing platform and data analysis software specifically designed for forensic genomics. With about 200 genetic markers in a single workflow, the MiSeq FGx Solution offers the most comprehensive multiplex of STRs and SNPs and the most straightforward path to human identification.\u003c\/p\u003e\u003ch2\u003eProcedure\u003c\/h2\u003e\u003cp\u003eThe ForenSeq Signature Plus Kit includes all reagents required to prepare DNA libraries for sequencing, including PCR reagents, UDI plate and purification and normalization beads. Simultaneously interrogate your choice of markers in a single amplification. Choose from either DNA Primer Set A (DPMA) or DNA Primer Set B (DPMB) to consolidate multiple existing capillary electrophoresis (CE)-based kits.\u003c\/p\u003e\u003ch2\u003eApplications\u003c\/h2\u003e\u003cp\u003eThe ForenSeq Signature Plus Kit is part of the ForenSeq MiSeq FGx Forensic Genomics Solution, a complete, fully validated DNA-to-data workflow specifically designed for forensic genomics applications.\u003c\/p\u003e\u003ch2\u003eSoftware\u003c\/h2\u003e\u003cp\u003eThe ForenSeq Signature Plus Kit is part of an integrated workflow that sequences libraries on the MiSeq FGx Sequencing System and analyzes data in Universal Analysis Software (UAS). Designed, developed, and manufactured as a high performance, end-to-end solution for forensic samples, the entire portfolio is backed by extensive technical support. In addition, quality-controlled manufacturing ensures reproducibility with the convenience of all-in-one library prep kits.\u003c\/p\u003e\u003ch2\u003eDocuments\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/kithandbookandprotocol\/hb-3613-001-hb-forenseq-dna-sig-plus-1024-ww\" target=\"_blank\" rel=\"noopener\"\u003eForenSeq DNA Signature Plus Kit Handbook\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/usermanual\/hb-3616-001-ug-uas-dna-sigplus-1024-ww\" target=\"_blank\" rel=\"noopener\"\u003eUniversal Analysis Software for ForenSeq Signature Plus Module User Guide\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/brochureandguide\/qpro-5802-fly-hid-nippt-0324-ww\" target=\"_blank\" rel=\"noopener\"\u003ePaternity Doubts Erased\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/brochureandguide\/qpro-11254-bro-hid-ngs-in-hid-0825-ww\" target=\"_blank\" rel=\"noopener\"\u003eReimagining Human Identification\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/scientificdocument\/qpro-8011-an-hid-age-estimation-ngs-dna-methylation-1224-ww\" target=\"_blank\" rel=\"noopener\"\u003eForensic age estimation with DNA methylation\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eOrdering Information\u003c\/h2\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eCat. no.\u003c\/th\u003e\n\u003cth\u003eProduct\u003c\/th\u003e\n\u003cth\u003eContents\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eV16000213\u003c\/td\u003e\n\u003ctd\u003eForenSeq Signature Plus Kit (96)\u003c\/td\u003e\n\u003ctd\u003eIncludes all the required reagents to prepare sequencing libraries from forensic DNA samples; part of the MiSeq FGx Forensic Genomics Solution\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eV16000214\u003c\/td\u003e\n\u003ctd\u003eForenSeq Signature Plus Kit (384)\u003c\/td\u003e\n\u003ctd\u003eIncludes all the required reagents to prepare sequencing libraries from forensic DNA samples; part of the MiSeq FGx Forensic Genomics Solution\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003e\u003cem\u003eThe ForenSeq Signature Plus Kit is intended for molecular biology applications in forensic, human identity, and paternity testing. This product is not intended for diagnosis, prevention, or treatment of a disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"QIAGEN","offers":[{"title":"96 reactions","offer_id":46798468907087,"sku":"V16000213","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"384 reactions","offer_id":46798468939855,"sku":"V16000214","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/1_5_WebFullSizeImage_7fc8a1c7-e14d-4ce8-aa2c-bdcde88c71c1.jpg?v=1789653406"},{"product_id":"qiagen-forenseq-mainstay-kit-v16000142","title":"Verogen ForenSeq MainstAY Kit","description":"\u003cp\u003eTarget the core autosomal and Y-STRs with the ForenSeq MainstAY Product Line, the most accessible way to generate highly discriminating data for mainstream casework and forensic genetic genealogy confirmatory testing. Choose between two geographically relevant options like the NDIS-approved ForenSeq MainstAY Kit, which is purpose-built to support a majority of national database STR uploads, or the ForenSeq MainstAY SE kit which includes the highly polymorphic SE33 marker. By focusing on established STRs used in routine human identification applications and maintaining compatibility with global databases, the MainstAY products ease the transition to next-generation sequencing. The familiar and proven ForenSeq workflow generates more comprehensive DNA profiles for up to 96 evidence samples with less than 2 hours of hands-on time.\u003c\/p\u003e\u003ch2\u003eFeatures\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eLargest combination of established STRs in one amplification\u003c\/li\u003e\n\u003cli\u003eMeets European\/SWGDAM minimal Y-haplotype, CODIS, Interpol and ESS requirements\u003c\/li\u003e\n\u003cli\u003eFull profiles from low input of gDNA\u003c\/li\u003e\n\u003cli\u003eDetect alleles from challenging samples with superior balance and high call rates\u003c\/li\u003e\n\u003cli\u003eSimultaneously sequence 96 samples per run\u003c\/li\u003e\n\u003cli\u003eApproved for upload to the National DNA Index System (NDIS) for casework (not SE)\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003ePerformance\u003c\/h2\u003e\u003cp\u003eForenSeq MainstAY offers an easy transition point to include next-generation sequencing (NGS) into your operational workflow. NGS supports the simultaneous typing of various categories of STRs in a single reaction, enabling the recovery of the maximum information from a forensic sample. NGS also combines the discriminatory power of STRs with additional sequence-level variation, which can resolve isoalleles within an STR. The ForenSeq MainstAY Kit contains reagents to amplify 27 autosomal and 25 Y-STR loci as small amplicons and generate sequencing data on the MiSeq FGx Sequencing System using the MiSeq FGx Reagent Micro Kit. With this workflow, both sequence and allele length polymorphism in the Au-STRs and Y- STRs can be identified in a single amplification. This eliminates the need to run multiple workflows and maximizes the informative value of a forensic sample, thereby increasing the statistical power of inclusion. NGS also eliminates the problem of overlapping alleles, allowing users to interrogate more alleles in the multiplex.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eThe combination of STR loci and Amelogenin is an effective tool for human identification\u003c\/li\u003e\n\u003cli\u003eMaintains compatibility with existing databases worldwide\u003c\/li\u003e\n\u003cli\u003eLow input recommendations of 1 ng gDNA deliver a reproducibly high call rate\u003c\/li\u003e\n\u003cli\u003eAnalyze sequence data in a familiar and easy-to-use interface with the MainstAY Analysis Module\u003c\/li\u003e\n\u003cli\u003eGenerate reports in less than 1.5 days\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eIncluding 27 Au-STRs, 25 Y-STRs and Amelogenin in a single reaction provides a higher expected likelihood ratio than most commercially available autosomal STR kits and enables direct comparisons of single-source profiles (e.g., in database searches and international data sharing) regardless of the assay used to type the comparative sample. The genetic profile generated by ForenSeq MainstAY enables casework searches with Au-STRs as well as haplotype searches with a Y-STR database. The Y-STRs produce a haplotype profile from male DNA which makes them extremely useful when working with male\/female mixtures. In the presence of only one male contributor, it can be used to exclude potential male contributors.\u003c\/p\u003e\n\u003ctable\u003e\n\u003ccaption\u003eMarkers in the ForenSeq MainstAY Kit\u003c\/caption\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003ctd\u003eAutosomal STRs\u003c\/td\u003e\n\u003ctd\u003eY-STRs\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eD1S1656 vWA CSF1PO SE33* D20S482\u003c\/td\u003e\n\u003ctd\u003eDYF387S1 DYS43 DYS393 DYS570\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTPOX D12S391 D6S1043 D21S11\u003c\/td\u003e\n\u003ctd\u003eDYS19 DYS448 DYS437 DYS576\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eD2S441 D13S317 D7S820 PentaD\u003c\/td\u003e\n\u003ctd\u003eDYS385a-b DYS460 DYS438 DYS612\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eD2S1338 PentaE D8S1179 D22S1045\u003c\/td\u003e\n\u003ctd\u003eDYS389I DYS481 DYS635 Y-GATA-H4\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eD3S1358 D16S539 D9S1122 TH01\u003c\/td\u003e\n\u003ctd\u003eDYS389II DYS505 DYS643\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eD4S2408 D17S1301\u003c\/td\u003e\n\u003ctd\u003eDYS390 DYS522\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFGA D18S51\u003c\/td\u003e\n\u003ctd\u003eDYS391 DYS533\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eD5S818 D19S433 D10S1248\u003c\/td\u003e\n\u003ctd\u003eDYS392 DYS549\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd colspan=\"2\"\u003eAmelogenin\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e* DPMD only for ForenSeq MainstAY SE\u003c\/p\u003e\n\u003cp\u003eThe maximum number of libraries that can be simultaneously sequenced depends upon the number of reads or the depth of coverage (DoC) desired per locus. Balanced read coverage across amplicons is also critical to locus and allele recovery. The ForenSeq MainstAY Kit has a small number of markers multiplexed in a single sequencing reaction resulting in high overall coverage. Interlocus balance was determined using MainstAY libraries from 1 ng of input DNA from 46 male Coriell samples, including a positive amplification control, 49 female Coriell samples, and an NTC. Average coverage across the Au-STRs and Y-STRs for male samples was 669 and 469 reads, respectively. Average coverage for the Au-STRs for female samples was 1065 reads. The fold difference between the Au-STRs with highest and lowest depth of coverage was 15x, while the fold difference between the Y-STRs with highest and lowest reads was 4.6x.The median interlocus balance for male samples, expressed as a percentage of total reads, was 1.9% (Au-STRs: 2.2% and Y-STRs: 1.6%). For female samples, the interlocus balance for the Au-STRs was 3.7%.\u003c\/p\u003e\n\u003cp\u003eThe intralocus balance (ILB) or heterozygous balance (HB) was calculated as a ratio of the lower number of allele reads to the higher number of allele reads for a heterozygote pair. Compared to CE-based STRs, NGS shows a larger range for the ILB due to amplification biases for smaller amplicons during library preparation and sequencing. ILB for heterozygotes and isometric genotype pairs was evaluated using the 1-ng DNA samples in this study for each sample and locus. All markers in the panel exhibited ILB values above 60% with a median ILB of 86%. The coverage and low variation of the ForenSeq MainstAY Kit indicates that amplicons are well balanced, which reduces the likelihood of locus or allelic dropout and improves the identification of minor contributors in a mixture (see figure ”Intralocus balance for genetic markers included in the ForenSeq MainstAY Kit with 1-ng DNA input”).\u003c\/p\u003e\n\u003cp\u003eThe ability to generate genotypes and haplotypes across a range of inputs was evaluated using serially diluted gDNA in template amounts of 1 ng, 500 pg, 250 pg, 125 pg, 62.5 pg, 31.25 pg, 15.625 pg, and 7.82 pg, in triplicate. 96 libraries were simultaneously sequenced using the MiSeq FGx Reagent Micro Kit. The ForenSeq MainstAY Kit offers a high level of sensitivity, generating full profiles (no allele loss) and 100% call rate with as little as 62.5 pg of input DNA when 96 libraries were simultaneously sequenced. To determine allele call rate and comparative accuracy of the sequencing-based genotype data, the genotypes and haplotypes were generated with the MainstAY Analysis Module in the Universal Analysis Software using the default settings and compared to orthogonal genotyping data from conventional genotyping methods (CE fragment length detection for STRs). Au-STRs demonstrated 100% concordance down to 62.5 pg, with a concordance of 95% even at 31 pg. Y-STRs demonstrated 100% concordance down to 125 pg, with 91% concordance down to 31 pg. All discordant calls were the result of stutter that exceeded the default stutter filter set for 1 ng samples..\u003c\/p\u003e\n\u003cp\u003eTo evaluate the concordance of the genotypes and haplotypes generated by the ForenSeq MainstAY Kit, 31 libraries including the NIST SRM 2391d standards, Coriell DNAs, a positive amplification control, and three NTCs were prepared and sequenced in triplicate. Data was analyzed using the MainstAY analysis module in the Universal Analysis Software with default analysis thresholds and stutter filters. Accuracy of the genotypes and haplotype alleles was determined by comparing it to orthogonal CE data. Precision and call rates were determined using repeatability and reproducibility experiments where libraries were prepared and sequenced from 15 control DNA samples in quadruplicate with one positive amplification control and three NTCs by three operators on three different MiSeq FGx instruments. High accuracy was observed in Au-STRs (99.82%) and Y-STRs (100%). Six discordant alleles were detected out of 3261 Au-STR alleles. No discordant alleles were detected for the 774 Y-STRs alleles. Similarly, high precision rates of 99.87% and 99.42% were observed for Au-STRs and Y-STRs, respectively. All discrepancies were attributed to stutter alleles exceeding the default stutter filters.\u003c\/p\u003e\n\u003cp\u003eTo evaluate the ability of the ForenSeq MainstAY Kit to detect minor alleles in low level contributors, mixtures of control female and male samples were generated at 1 ng, with the female sample as the major contributor. The percentage of the minor contributor in the mixture ranged from 50% to 0.2%. The number of unique, unshared minor allele contributor alleles in the mixture was assessed using the default analytical and interpretation thresholds, as well as stutter filters in the MainstAY analysis module in the Universal Analysis Software. At 50% minor contributor, 31 unique minor autosomal alleles and 27 Y alleles were detected. Approximately 15 unique minor autosomal alleles (50% unique Au-STR alleles) and 26 Y alleles were detectable at 5% minor contribution. At 1% minor contribution, over 10 Y-STR loci were detectable. ForenSeq MainstAY enables efficient identification of minor contributors in a mixture even at low level contributions.\u003c\/p\u003e\n\u003cp\u003eThe ability to type genotypes and haplotypes of degraded DNA samples with the ForenSeq MainstAY workflow was assessed using partially degraded gDNA that mimics forensic samples exposed to environmental and chemical stresses. Libraries from 1 ng of degraded blood from 30 samples, 1 positive amplification control and NTC, in triplicate were prepared and sequenced using the Miseq FGx Reagent Micro Kit. Degradation index (DI) was used to assess the sample quality of the libraries. Samples with a DI of 1–4 were considered not-degraded, samples with a DI of 4–10 were considered moderately degraded, and those with a DI \u0026gt;10 were considered severely degraded. The samples tested with MainstAY had a DI that ranged from 1 to 56, spanning low, moderate, and highly degraded samples. All STRs were accurately typed in samples with no degradation. Samples with moderate degradation showed \u0026gt;85% call rate of accurately typed STRs, while samples that were severely degraded had a call rate \u0026gt;71%, showing minimal loss of amplifiable STRs. The sample with the highest DI of 56 showed 60% recovery of alleles (40 of 74). ForenSeq MainstAY enables the detection of a high number of alleles even from severely degraded samples.\u003c\/p\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003ctd\u003eFeature\u003c\/td\u003e\n\u003ctd\u003eDetails\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eDNA input recommendation\u003c\/td\u003e\n\u003ctd\u003e1 ng per sample from gDNA, buccal swabs, FTA card; 1.2 mm per sample from FTA card punch\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eKit configuration\u003c\/td\u003e\n\u003ctd\u003e96 reaction kit and 384 reaction kit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eRecommended multiplexing capacity\u003c\/td\u003e\n\u003ctd\u003e8–96 samples per run\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLocus multiplexing capacity\u003c\/td\u003e\n\u003ctd\u003eSimultaneous analysis of 52 genetic markers\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePrimer mix content\u003c\/td\u003e\n\u003ctd\u003e27 global autosomal STRs including CODIS and European Standard set; 25 Y-STRs including minimum set for the Y Haplotype Reference Database (YHRD)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAmplicon size\u003c\/td\u003e\n\u003ctd\u003eMean: 235 bp; Maximum: 481 bp\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLow level mixture detection\u003c\/td\u003e\n\u003ctd\u003eDetects minor contributors at 5%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTotal prep time\u003c\/td\u003e\n\u003ctd\u003eLibrary: 7 hours and 15 minutes; Hands-on: 1 hour and 30 minutes\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTotal sequencing time\u003c\/td\u003e\n\u003ctd\u003eAbout 28 hours with the MiSeq FGx Reagent Kit; about 22 hours with the MiSeq FGx Reagent Micro Kit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003ch2\u003ePrinciple\u003c\/h2\u003e\u003cp\u003eThe ForenSeq MainstAY workflow is built on the familiar ForenSeq chemistry that underpins the Verogen library prep portfolio. This sensitive, PCR-based assay efficiently amplifies 53 markers with integrated Unique Dual Indices (UDIs), generating short amplicons that increase the likelihood of detecting alleles from degraded DNA. A DNA extract input volume of 8 μl supports flexibility for low concentration samples and dilution of inhibited samples.\u003c\/p\u003e\n\u003cp\u003eThis fully kitted solution includes a positive amplification control, enabling easy purchasing and calibration. The kit enables sequencing and analysis of up to 96 samples on the MiSeq FGx Reagent Micro Kit using the long paired-end read capability of the MiSeq FGx Sequencing System, maximizing sample throughput and minimizing cost per sample. A low gDNA input recommendation of 1 ng enables reliable and reproducible recovery of full profiles from high-quality single-source samples all the way down to 62.5 pg low input and difficult samples.\u003c\/p\u003e\u003ch2\u003eProcedure\u003c\/h2\u003e\u003cp\u003eThe ForenSeq MainstAY Kit enables an end-to-end workflow in under 30 hours when used in conjunction with the MiSeq FGx Sequencing System, the MiSeq FGx Reagent Micro Kit and the MainstAY analysis module in the Universal Analysis Software (UAS). The MainstAY Analysis Module provides guided exploration, rich visualization with project and sample views, and meticulous reviews of STR allele calls with extensive filtering and sorting capabilities. It also generates human-readable reports that can be exported in multiple formats. This integrated workflow provides a cost-effective entry point to laboratories considering NGS for forensic applications.\u003c\/p\u003e\n\u003cp\u003eThe workflow includes five safe stopping points and a pre-mixed adapter plate that increases library preparation efficiency and ease. The workflow is compatible with a variety of common sources of forensic DNA, such as extracted gDNA, crude lysates, and storage media card punches, such as FTA.\u003c\/p\u003e\u003ch2\u003eApplications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eFocused and efficient analysis for volume casework\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eSimultaneously interrogate the largest collection of well characterized loci including 27 autosomal STRs and 25 Y-STR markers for up to 96 samples. Generate balanced profiles compatible with all existing STR databases with as little as 100 pg. Efficiently analyze data with a minimal interaction analysis module and choose from a range of upload-ready export options compatible with regional database requirements.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eBetter data, similar cost\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eObtain highly discriminating data for core CODIS and European Standard Set (ESS) STR loci in a single amplification and sequencing run at a comparable cost to traditional CE analysis. Unlock the power of next-generation sequencing whatever your throughput requirement with a choice of two sequencing kit sizes.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eFully integrated and supported\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThe end-to-end workflow is based on the established ForenSeq process, enabling a diverse range of DNA analysis on a single, proven platform. The ForenSeq MainstAY Kit links seamlessly with UAS for rapid data assessment and single-click report generation.\u003c\/p\u003e\u003ch2\u003eSoftware\u003c\/h2\u003e\u003cp\u003eThe MainstAY analysis module in the Universal Analysis Software (UAS) enables the evaluation of sequencing data using familiar quality scores, threshold and guidance. Preconfigured analysis settings are provided within the solution that can be modified by the laboratory as needed. In addition, this module has been designed to increase the operational efficiency of high-volume forensic labs, with streamlined project and sample overviews that make it easy to review markers with QC indicators. New sorting and filtering capabilities allow users to categorize and evaluate a subset of STRs using a variety of QC indicators. Easier sequence analysis of STR alleles from populations of mixed alleles, such as isometric heterozygotes, is made possible by the ability to easily navigate between both allele calls and sequence level information.\u003c\/p\u003e\u003ch2\u003eDocuments\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/validationandtechnicaldocument\/qpro-6228-ti-hid-mainstayproductline-0424-ww\" target=\"_blank\" rel=\"noopener\"\u003eForenSeq MainstAY Product Line\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/kithandbookandprotocol\/forenseq-mainstay-reference-guide-pcr1-vd2020050-c\" target=\"_blank\" rel=\"noopener\"\u003eForenSeq MainstAY Kit Reference Guide\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/analysissoftware\/universal-analysis-software-v2-reference-guide-mainstay-vd2022001-reva\" target=\"_blank\" rel=\"noopener\"\u003eUniversal Analysis Software MainstAY Product Line Module v2.0 Reference Guide\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/ebook.qiagen.com\/books\/muhf\/\" target=\"_blank\" rel=\"noopener\"\u003eIntegrated workflows for sexual assault analysis: Reliable forensic workflows for complex sexual assault evidence\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/brochureandguide\/prom-19028-001-1125732-fly-hid-ngs-0821-ww\" target=\"_blank\" rel=\"noopener\"\u003eA new horizon of human identification possibilities with NGS\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/brochureandguide\/qpro-5802-fly-hid-nippt-0324-ww\" target=\"_blank\" rel=\"noopener\"\u003ePaternity Doubts Erased\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/brochureandguide\/qpro-11254-bro-hid-ngs-in-hid-0825-ww\" target=\"_blank\" rel=\"noopener\"\u003eReimagining Human Identification\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/scientificdocument\/qpro-6938-an-hid-cevsngs-degraded-samples-ver07-1024-ww\" target=\"_blank\" rel=\"noopener\"\u003eStreamlining degraded sample processing in forensic laboratories: Developing a decision tree for capillary electrophoresis and next-generation sequencing platforms\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eOrdering Information\u003c\/h2\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eCat. no.\u003c\/th\u003e\n\u003cth\u003eProduct\u003c\/th\u003e\n\u003cth\u003eContents\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eV16000142\u003c\/td\u003e\n\u003ctd\u003eVerogen ForenSeq MainstAY Kit (96)\u003c\/td\u003e\n\u003ctd\u003eIncludes all the required reagents for 96 reactions to prepare sequencing libraries generating data for mainstream casework and forensic genetic genealogy confirmatory testing\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eV16000128\u003c\/td\u003e\n\u003ctd\u003eVerogen ForenSeq MainstAY Kit (384)\u003c\/td\u003e\n\u003ctd\u003eIncludes all the required reagents for 384 reactions to prepare sequencing libraries generating data for mainstream casework and forensic genetic genealogy confirmatory testing\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eV16000183\u003c\/td\u003e\n\u003ctd\u003eVerogen ForenSeq MainstAY SE Kit (96)\u003c\/td\u003e\n\u003ctd\u003eIncludes all the required reagents for 96 reactions to prepare sequencing libraries generating data for mainstream casework and forensic genetic genealogy confirmatory testing including the same markers as in ForenSeq MainstAY Kit + SE33\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003e\u003cem\u003eThe Verogen ForenSeq MainstAY Kit is intended for molecular biology applications in forensic, human identity, and paternity testing. This product is not intended for diagnosis, prevention, or treatment of a disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"QIAGEN","offers":[{"title":"96 reactions","offer_id":46798469038159,"sku":"V16000142","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"384 reactions","offer_id":46798469070927,"sku":"V16000128","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"SE, 96 reactions","offer_id":46798469103695,"sku":"V16000183","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/1_5_WebFullSizeImage_2ced69b5-b498-4ff2-8b49-79f0f3ce9c4e.jpg?v=1789653411"},{"product_id":"qiagen-forenseq-mtdna-control-region-kit-v16000085","title":"Verogen ForenSeq mtDNA Control Region Kit","description":"\u003cp\u003eThe ForenSeq mtDNA Control Region Kit offers convenient, efficient library prep for interrogating the control region of the mitochondrial genome (mtGenome) with minimal DNA input and optimum sensitivity. Leveraging proven ForenSeq chemistry, the kit produces a concise data set from the entire control region for direct upload to CODIS. Multiplexing capability boosts operational efficiency without increases to costs or time.\u003c\/p\u003e\u003cp\u003eIncludes all the primary reagents necessary for 48 reactions for the preparation of complete mtDNA control region libraries\u003c\/p\u003e\u003ch2\u003eFeatures\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eOptimum sensitivity from minimal DNA input\u003c\/li\u003e\n\u003cli\u003eEnhanced variant detection using small amplicons from the latest databases\u003c\/li\u003e\n\u003cli\u003eExcellent resolution for severely degraded samples\u003c\/li\u003e\n\u003cli\u003eMultiplexing capability further boosts operational efficiency\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003ePerformance\u003c\/h2\u003e\u003cp\u003eThe ForenSeq mtDNA Control Region Kit links a powerful assay with industry-leading sequencing and integrates seamlessly with intuitive software for optimum laboratory efficiency. The ForenSeq mtDNA Control Region workflow is completely flexible and scalable for all throughput requirements, allowing laboratories to quickly generate complete mtDNA control region results for up to 48 samples simultaneously in less than two working days. For low throughput requirements, the kit’s 48 reactions maintain a 12-month shelf-life and for higher demand laboratories, a similar library preparation routine makes automation easy.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eShort mean amplicon size for maximum variant detection\u003c\/li\u003e\n\u003cli\u003eOptimized for inhibitor tolerance\u003c\/li\u003e\n\u003cli\u003eFlexible and scalable throughput\u003c\/li\u003e\n\u003cli\u003eIntegrated workflow for optimum laboratory efficiency\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThe high density of mutations concentrated in the mtDNA control region and the degraded nature of most forensic samples in which mtDNA analysis is used make optimal primer design challenging. The ForenSeq mtDNA Control Region kit is optimized to generate complete and actionable coverage, even for very low input amounts.\u003c\/p\u003e\n\u003cp\u003eTo improve performance on highly degraded material, the ForenSeq mtDNA Control Region kit uses more than 120 primers, designed from recently curated mtDNA variant and frequency data, generating 18 primary amplicons in the mtDNA control region. All primary amplicons are \u0026lt;150 bp in length, many \u0026lt; 100 bp – the lowest average amplicon size of any current commercial mtDNA assay system. All amplicons have a minimum overlap of 3 bp to avoid gaps in sequence following post run, bioinformatic trimming. A buffer system optimized for inhibitors that creates a robust amplification environment (see figure “An improved ForenSeq buffer system maximizes performance“).\u003c\/p\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003ctd\u003eFeature\u003c\/td\u003e\n\u003ctd\u003eDetails\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eTarget size\u003c\/td\u003e\n\u003ctd\u003e1200 bp mtDNA control region\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eDNA input recommendation\u003c\/td\u003e\n\u003ctd\u003e100 pg gDNA and mtDNA per sample\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eSample types\u003c\/td\u003e\n\u003ctd\u003eDNA extracted from a range of degraded samples, including bone, teeth and hair shaft\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eRecommended multiplexing capacity\u003c\/td\u003e\n\u003ctd\u003e3–48 libraries per run\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eNumber of primers\u003c\/td\u003e\n\u003ctd\u003e\u0026gt;120\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eNumber of amplicons\u003c\/td\u003e\n\u003ctd\u003e18\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAverage amplicon size\u003c\/td\u003e\n\u003ctd\u003e118 bp\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAmplicon overlap\u003c\/td\u003e\n\u003ctd\u003e≥ 3 bp\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTotal library prep time\u003c\/td\u003e\n\u003ctd\u003e7 hours and 45 minutes\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eHands-on time\u003c\/td\u003e\n\u003ctd\u003e1 hour and 30 minutes\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003ch2\u003ePrinciple\u003c\/h2\u003e\u003cp\u003eThe PCR-based assay deploys small amplicons sourced from the latest mitochondrial (mtDNA) databases for enhanced variant detection. A tiled approach overlaps the amplicons to prevent the sequence gaps that can lead to data loss, particularly in degraded samples. Complementing this tiled primer design, an enhanced buffer system delivers exceptional resistance to calcium, humic acid, and other relevant PCR inhibitors.\u003c\/p\u003e\u003ch2\u003eProcedure\u003c\/h2\u003e\u003cp\u003eThis user-friendly, automation-compatible solution provides a common workflow for a variety of study designs spanning multiple applications. The protocol includes two normalization methods to tailor library prep for a broad range of input material, from high-quality genomic DNA (gDNA) through low-level and complex samples, while a low input requirement expands possibilities for the most challenging samples. For efficient use of the reagent kit and accurate read assignment, index adapters provided in the library prep kit allow pooling and sequencing of up to 48 samples in one run.\u003c\/p\u003e\u003ch2\u003eApplications\u003c\/h2\u003e\u003cp\u003eMitochondrial DNA is a powerful alternative source of information when nuclear DNA is compromised or absent. Used for rootless hairs, teeth, bones, and other challenging sources, mtDNA has become routine for missing persons and disaster victim identification efforts. Previously, quality and scaling issues associated with traditional Sanger sequencing methods have confined mtDNA to a limited role in a few specialty centers. Verogen mtDNA workflows offer a unique combination of performance, efficiency, and ease of use so that any lab, of any size, can transition mtDNA analysis from Sanger sequencing to NGS, or improve your results obtained from other NGS technologies.\u003c\/p\u003e\u003ch2\u003eSoftware\u003c\/h2\u003e\u003cp\u003eThe ForenSeq mtDNA Control Region Kit pairs seamlessly with the ForenSeq mtDNA Analysis Module in UAS for ease-of-use and rapid review of mtDNA data. The software analyzes sequencing output for the control region and provides results less than one hour after run completion. Laboratories can review summarized or detailed results and compare up to nine samples on a clear and interactive user interface. Reports are compatible with multiple DNA databases.\u003c\/p\u003e\u003ch2\u003eDocuments\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/validationandtechnicaldocument\/qpro-6233-ti-hid-forenseq-mtdna-control-region-0824-ww\" target=\"_blank\" rel=\"noopener\"\u003eForenSeq mtDNA Control Region Solution\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/kithandbookandprotocol\/hb-3679-001-fseq-mtcr-prepstation-1025-ww\" target=\"_blank\" rel=\"noopener\"\u003eForenSeq mtDNA Control Region Kit Handbook for PrepStation\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/kithandbookandprotocol\/forenseq-mtdna-control-region-kit-reference-guide-vd2018024-b\" target=\"_blank\" rel=\"noopener\"\u003eForenSeq mtDNA Control Region Kit Reference Guide\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/additionalresource\/forenseq-mtdna-control-region-kit-materials-vd2020044-a\" target=\"_blank\" rel=\"noopener\"\u003eForenSeq mtDNA Control Region Kit Materials\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/brochureandguide\/prom-19028-001-1125732-fly-hid-ngs-0821-ww\" target=\"_blank\" rel=\"noopener\"\u003eA new horizon of human identification possibilities with NGS\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/brochureandguide\/qpro-11254-bro-hid-ngs-in-hid-0825-ww\" target=\"_blank\" rel=\"noopener\"\u003eReimagining Human Identification\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/analysissoftware\/universal-analysis-software-v2-0-reference-guide-vd2019002-d-2\" target=\"_blank\" rel=\"noopener\"\u003eUniversal Analysis Software v2.0 and above Reference Guide\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eOrdering Information\u003c\/h2\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eCat. no.\u003c\/th\u003e\n\u003cth\u003eProduct\u003c\/th\u003e\n\u003cth\u003eContents\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\u003ctr\u003e\n\u003ctd\u003eV16000085\u003c\/td\u003e\n\u003ctd\u003eVerogen ForenSeq mtDNA Control Region Kit\u003c\/td\u003e\n\u003ctd\u003eIncludes all the primary reagents necessary for 48 reactions for the preparation of complete mtDNA control region libraries\u003c\/td\u003e\n\u003c\/tr\u003e\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003e\u003cem\u003eThe Verogen ForenSeq mtDNA Control Region Kit is intended for molecular biology applications in forensic, human identity, and paternity testing. This product is not intended for diagnosis, prevention, or treatment of a disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"QIAGEN","offers":[{"title":"Default Title","offer_id":46798469005391,"sku":"V16000085","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/1_5_WebFullSizeImage_7fc8a1c7-e14d-4ce8-aa2c-bdcde88c71c1.jpg?v=1789653406"},{"product_id":"qiagen-forenseq-mtdna-whole-genome-kit-v16000086","title":"Verogen ForenSeq mtDNA Whole Genome Kit","description":"\u003cp\u003eThe ForenSeq mtDNA Whole Genome Kit offers a convenient and cost-effective library prep for sequencing the whole mitochondrial genome (mtGenome) with minimal DNA input and exceptional data recovery. Leveraging proven ForenSeq chemistry, the kit produces expanded data sets that promote population studies or provide additional resolution for severely degraded samples. Moreover, this solution has the lowest list price of any commercial whole genome assay. Multiplexing capability further boosts operational efficiency without increases to costs or time.\u003c\/p\u003e\u003cp\u003eIncludes all the primary reagents necessary for 48 reactions for the preparation of complete whole mtDNA genome libraries\u003c\/p\u003e\u003ch2\u003eFeatures\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eExceptional data recovery from minimal DNA input\u003c\/li\u003e\n\u003cli\u003eExpanded panel promotes population studies\u003c\/li\u003e\n\u003cli\u003eProvides additional resolution for severely degraded samples\u003c\/li\u003e\n\u003cli\u003eMultiplexing capability further boosts operational efficiency\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003ePerformance\u003c\/h2\u003e\u003cp\u003eThe ForenSeq mtDNA Whole Genome Kit features the highest resolution for mtGenome sequencing in the Verogen library prep portfolio. Tiled amplicons, fit-for-purpose buffers, and a thoughtfully designed protocol enable support for the lower end of DNA input amounts, various sample types, and a broad range of forensic and database applications, including missing persons, disaster victim identification (DVI), and population studies.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eHigh sensitivity across a range of gDNA inputs\u003c\/li\u003e\n\u003cli\u003eEnhanced recovery of low input samples\u003c\/li\u003e\n\u003cli\u003eRobust resistance to common inhibitors\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThe protocol includes an optional second purification to further improve the performance of low-level and complex samples. The figure “\u003cem\u003eHigh coverage across a range of input DNA amounts\u003c\/em\u003e” presents a comparison of coverage results for libraries with and without the second purification. Compared to a single purification, two purifications show progressive coverage advancements, culminating with 90% improvement at 2 pg. Another challenge of forensic sample analysis is the frequent presence of PCR inhibitors that can compromise library prep. When varying amounts of three inhibitors common in forensic mtDNA samples were added to 100 pg of Control DNA HL60, results shown in the figure “\u003cem\u003eBuffers highly resistant to relevant PCR inhibitors\u003c\/em\u003e” demonstrated high resistance with consistent coverage across all inputs.\u003c\/p\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003ctd\u003eFeature\u003c\/td\u003e\n\u003ctd\u003eDetails\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eDNA input recommendation\u003c\/td\u003e\n\u003ctd\u003e100 pg gDNA per sample\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eKit configuration\u003c\/td\u003e\n\u003ctd\u003e48 reactions\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMultiplexing capacity\u003c\/td\u003e\n\u003ctd\u003e16 libraries per run\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eNumber of primers\u003c\/td\u003e\n\u003ctd\u003e\u0026gt;500\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eNumber of amplicons\u003c\/td\u003e\n\u003ctd\u003e245\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAverage amplicon size\u003c\/td\u003e\n\u003ctd\u003e131 bp\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAmplicon overlap\u003c\/td\u003e\n\u003ctd\u003e≥3 bp\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTotal library prep time\u003c\/td\u003e\n\u003ctd\u003e7 hours and 45 minutes\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eHands-on time\u003c\/td\u003e\n\u003ctd\u003e1 hour and 45 minutes\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003ch2\u003ePrinciple\u003c\/h2\u003e\u003cp\u003eThe targeted PCR-based assay deploys small amplicons sourced from the latest mtDNA databases for enhanced variant detection. A tiled primer approach overlaps the amplicons to prevent the sequence gaps that can lead to data loss, particularly in degraded samples. Complementing this tiled primer design, an enhanced buffer system delivers exceptional resistance to calcium, humic acid, and other relevant PCR inhibitors.\u003c\/p\u003e\u003ch2\u003eProcedure\u003c\/h2\u003e\u003cp\u003eThis user-friendly, automation-compatible solution provides a common workflow for a variety of study designs spanning multiple applications. The protocol includes two normalization methods to tailor library prep for a broad range of input material, from high-quality genomic DNA (gDNA) through low-level and complex samples. A low input requirement expands possibilities for the most challenging samples. For efficient use of the reagent kit and accurate read assignment, index adapters provided in the library prep kit allow pooling and sequencing of up to 16 samples in one run. The tiled amplicon design of the whole genome kit is suited for analysis of the entire 16,569 bp human mtGenome. The assay includes reagents to amplify approximately 500 small amplicons and cover the entire genome in two PCR reactions.\u003c\/p\u003e\u003ch2\u003eApplications\u003c\/h2\u003e\u003cp\u003eMitochondrial DNA is a powerful alternative source of information when nuclear DNA is compromised or absent. Used for rootless hairs, teeth, bones, and other challenging sources, mtDNA has become routine for missing persons and disaster victim identification efforts. Previously, quality and scaling issues associated with traditional Sanger sequencing methods have confined mtDNA to a limited role in a few specialty centers. Verogen mtDNA workflows offer a unique combination of performance, efficiency, and ease of use so that any lab, of any size, can transition mtDNA analysis from Sanger sequencing to NGS, or improve results obtained from other NGS technologies.\u003c\/p\u003e\u003ch2\u003eSoftware\u003c\/h2\u003e\u003cp\u003eFor rapid review of mtDNA data, the ForenSeq mtDNA Whole Genome Kit pairs seamlessly with the ForenSeq mtDNA Analysis Module in Universal Analysis Software (UAS). UAS provides an NGS platform for analyzing and managing forensic genomic data, simplifying complex bioinformatics. The software analyzes sequencing output for the whole mitochondrial genome and provides results less than one hour after run completion. Laboratories can review summarized or detailed results and compare up to nine samples on a clear and interactive user interface. Reports are compatible with multiple DNA databases.\u003c\/p\u003e\u003ch2\u003eDocuments\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/validationandtechnicaldocument\/qpro-6232-ti-hid-forenseq-mtdna-whole-genome-0824-ww\" target=\"_blank\" rel=\"noopener\"\u003eForenSeq mtDNA Whole Genome Kit\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/kithandbookandprotocol\/hb-3681-001-fseq-mtwg-prepstation-1025-ww\" target=\"_blank\" rel=\"noopener\"\u003eForenSeq mtDNA Whole Genome Kit Handbook for PrepStation\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/kithandbookandprotocol\/forenseq-mtdna-whole-genome-kit-reference-guide-vd2020006-a\" target=\"_blank\" rel=\"noopener\"\u003eForenSeq mtDNA Whole Genome Kit Reference Guide\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/additionalresource\/forenseq-mtdna-whole-genome-kit-materials-vd2020008-a\" target=\"_blank\" rel=\"noopener\"\u003eForenSeq mtDNA Whole Genome Kit Materials\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/brochureandguide\/prom-19028-001-1125732-fly-hid-ngs-0821-ww\" target=\"_blank\" rel=\"noopener\"\u003eA new horizon of human identification possibilities with NGS\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/brochureandguide\/qpro-11254-bro-hid-ngs-in-hid-0825-ww\" target=\"_blank\" rel=\"noopener\"\u003eReimagining Human Identification\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/analysissoftware\/universal-analysis-software-v2-0-reference-guide-vd2019002-d-2\" target=\"_blank\" rel=\"noopener\"\u003eUniversal Analysis Software v2.0 and above Reference Guide\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eOrdering Information\u003c\/h2\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eCat. no.\u003c\/th\u003e\n\u003cth\u003eProduct\u003c\/th\u003e\n\u003cth\u003eContents\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\u003ctr\u003e\n\u003ctd\u003eV16000086\u003c\/td\u003e\n\u003ctd\u003eVerogen ForenSeq mtDNA Whole Genome Kit\u003c\/td\u003e\n\u003ctd\u003eIncludes all the primary reagents necessary for 48 reactions for the preparation of complete whole mtDNA genome libraries\u003c\/td\u003e\n\u003c\/tr\u003e\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003e\u003cem\u003eThe Verogen ForenSeq mtDNA Whole Genome Kit is intended for molecular biology applications in forensic, human identity, and paternity testing. This product is not intended for diagnosis, prevention, or treatment of a disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"QIAGEN","offers":[{"title":"Default Title","offer_id":46798469201999,"sku":"V16000086","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/1_5_WebFullSizeImage_7fc8a1c7-e14d-4ce8-aa2c-bdcde88c71c1.jpg?v=1789653406"},{"product_id":"qiagen-forenseq-kintelligence-kit-v16000120","title":"Verogen ForenSeq Kintelligence Kit","description":"\u003cp\u003eTarget 10,230 SNP markers explicitly curated for extended kinship outcomes with the ForenSeq Kintelligence Kit. The only sequence-based assay designed for forensic genetic genealogy (FGG), ForenSeq Kintelligence minimizes privacy concerns by excluding medically informative and minor allele frequency SNPs found in whole-genome sequencing (WGS) or array-based workflows. Robust PCR and primer designs allow for a single SNP multiplex that works across global populations.\u003c\/p\u003e\u003cp\u003eIncludes all the required reagents to prepare up to 12 low-quality forensic samples for forensic genetic genealogy\u003c\/p\u003e\u003ch2\u003eFeatures\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eStreamlined workflow for efficient assessment of forensically relevant SNPs\u003c\/li\u003e\n\u003cli\u003eForensically curated markers minimize medical data privacy concerns\u003c\/li\u003e\n\u003cli\u003eA single SNP multiplex works across global populations\u003c\/li\u003e\n\u003cli\u003ePair ForenSeq and GEDmatch workflows with application-specific support\u003c\/li\u003e\n\u003cli\u003eRetain full control of evidence and associated data in your laboratory\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003ePerformance\u003c\/h2\u003e\u003cp\u003eForenSeq Kintelligence is an integrated solution for forensic genetic genealogy (FGG). Libraries are prepared, sequenced and analyzed in a single, streamlined workflow for efficient assessment of forensically relevant SNPs. Developed according to existing STR-based methods, with input from on-market methods and established research and databases, the kit provides laboratories targeted sequencing and accurate analysis from forensic DNA samples, including those that are low-input and highly degraded. By applying a curated SNP set, a low input requirement, and a forensically validated workflow while building on established methodology, ForenSeq Kintelligence offers the opportunity to advance beyond dead ends and find resolution for cold cases, missing persons and unidentified human remains.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSequence compromised samples on a validated system for easy access to results\u003c\/li\u003e\n\u003cli\u003eCurated content design ensures data privacy with a SNP set selected for forensic relevance\u003c\/li\u003e\n\u003cli\u003eKeep evidence and associated data in your laboratory and retain full control\u003c\/li\u003e\n\u003cli\u003eFully integrated and supported to pair two familiar workflows, ForenSeq and GEDmatch\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eCold case samples and missing persons samples are often degraded due to advanced age, exposure to environmental elements and contaminants, and variable extraction and storage procedures. Accordingly, Verogen designed the ForenSeq Kintelligence Kit to deliver high recovery rates from compromised samples, performing studies analyzing degraded and inhibited casework-type samples and conducting a sensitivity assessment with control samples so that the kit reproducibly generates SNP calls across a range of input DNA amounts.\u003c\/p\u003e\n\u003cp\u003eForenSeq Kintelligence delivered high performance in mock casework studies that generated high call rates from degraded blood samples, teeth samples inhibited by calcium and contemporary bone samples subjected to the insults of cremation, burning and embalming. The sensitivity assessment evaluated control DNA at inputs ranging from 5 ng to 50 pg. The inputs ranging from 5 ng to 250 pg all achieved a call rate of 100%. Performance was similarly high at 100 pg and 50, at 99.9% and 99.6%, respectively. High average coverage of approximately 1500× across target sites allows these high call rates and ensures confident calls.\u003c\/p\u003e\n\u003cp\u003eGiven exposure to natural elements and prolonged degradation through age, cold case samples are prone to failing quality control checks and yielding poor coverage. This results in low DNA recovery and impacts allele call rates. To maximize recovery, ForenSeq Kintelligence buffers tolerate many common inhibitors including hematin, humic acid, indigo and tannic acid, and microbial contaminants such as E. coli. For 1 ng gDNA samples spiked with 10 ng microbial DNA, Verogen observed a SNP recovery rate of 100%. Control samples inhibited with spike-ins of significant amounts of other common forensic inhibitors demonstrated a high average call rate of 99.2%, comparable with control samples (see figure “An evaluation of inhibitor performance“). The high average call rate enables deep coverage of samples regardless of low input.\u003c\/p\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003ctd\u003eFeature\u003c\/td\u003e\n\u003ctd\u003eDetails\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eSample type\u003c\/td\u003e\n\u003ctd\u003egDNA from hair, bone, teeth, blood, semen and buccal swabs\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eDNA input recommendation\u003c\/td\u003e\n\u003ctd\u003e1 ng per sample\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eKit configuration\u003c\/td\u003e\n\u003ctd\u003e12 reactions\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eRecommended multiplexing capacity\u003c\/td\u003e\n\u003ctd\u003e3 libraries per run\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eNumber of SNPs\u003c\/td\u003e\n\u003ctd\u003e10,230\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMean amplicon size\u003c\/td\u003e\n\u003ctd\u003e\u0026lt; 150 bp\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTotal library prep time\u003c\/td\u003e\n\u003ctd\u003e8 hours\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eHands-on library prep time\u003c\/td\u003e\n\u003ctd\u003e1 hour and 55 minutes\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTotal sequencing time\u003c\/td\u003e\n\u003ctd\u003e28 hours\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003ch2\u003ePrinciple\u003c\/h2\u003e\u003cp\u003eA robust polymerase chain reaction (PCR) and primer design enables a single SNP multiplex, eliminating the need for multiple tests. The small average amplicon size of \u0026lt; 150 bp improves amplification efficiency and facilitates recovery and analysis of degraded DNA. Additionally, the ForenSeq Kintelligence Kit includes six unique dual index (UDI) adapters, which attach unique identifying sequences to each end of the sample for optimum data recovery.\u003c\/p\u003e\n\u003cp\u003eForenSeq Kintelligence queries 10,230 SNPs that have been carefully selected to support targeted sequencing for FGG.\u003c\/p\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003ctd\u003eCategory\u003c\/td\u003e\n\u003ctd\u003eNumber of SNPs\u003c\/td\u003e\n\u003ctd\u003ePercentage of total\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eAncestry SNPs\u003c\/td\u003e\n\u003ctd\u003e56\u003c\/td\u003e\n\u003ctd\u003e0.5%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eIdentity SNPs\u003c\/td\u003e\n\u003ctd\u003e94\u003c\/td\u003e\n\u003ctd\u003e1%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eKinship SNPs\u003c\/td\u003e\n\u003ctd\u003e9867\u003c\/td\u003e\n\u003ctd\u003e96%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePhenotype SNPs*\u003c\/td\u003e\n\u003ctd\u003e22\u003c\/td\u003e\n\u003ctd\u003e0.2%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eX-SNPs\u003c\/td\u003e\n\u003ctd\u003e106\u003c\/td\u003e\n\u003ctd\u003e1.2%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eY-SNPs\u003c\/td\u003e\n\u003ctd\u003e85\u003c\/td\u003e\n\u003ctd\u003e0.9%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e* Two SNPs overlap the ancestry and phenotype categories and are counted in the phenotype category only.\u003c\/p\u003e\n\u003cp\u003eThese SNPs overlap with relevant markers in the Illumina Infinium CytoSNP-850K BeadChip and Infinium Global Screening Array and are cross‑referenced against the Genome Aggregation Database (gnomAD) v3.0 and Single Nucleotide Polymorphism database (dbSNP) v151 for robust performance across global populations. Importantly, ForenSeq Kintelligence excludes the SNPs with known medical associations or low minor allele frequencies to limit privacy concerns and protect genetic health data.\u003c\/p\u003e\n\u003cp\u003eThe design of ForenSeq Kintelligence was influenced by ForenSeq DNA Signature Prep to include all biogeographical ancestry, identity and phenotype SNPs validated for investigative lead generation. Also included are informative Y-SNPs and X-SNPs to help with lineage and biological sex determination, respectively.\u003c\/p\u003e\n\u003cp\u003eAn optimized buffer system tolerates a range of inhibitors commonly found in forensic samples, such as calcium, indigo and humic acid, generating a \u0026gt; 98% call rate. Assay design provides a high level of process integrity and data quality so you can trust the analysis of even the most challenging forensic samples.\u003c\/p\u003e\u003ch2\u003eProcedure\u003c\/h2\u003e\u003cp\u003eForenSeq Kintelligence inputs are compatible with DNA extraction methods common in forensic laboratories. Library prep leverages the ForenSeq chemistry backbone that is foundational to the Verogen library prep portfolio. ForenSeq Kintelligence reagents enable preparation of up to 12 dual-indexed, human-specific libraries in 8 hours with only 1 hour and 55 minutes of hands-on time. Sequencing is completed in 28 hours and analysis in 1 hour for a fully integrated NGS workflow that delivers results, including a GEDmatch PRO report that users can directly upload to the database, in fewer than 40 hours. If a match exists, GEDmatch PRO produces results in fewer than 2 days.\u003c\/p\u003e\n\u003cp\u003eIn addition to providing rapid library prep that includes normalization, the ForenSeq chemistry offers a high degree of flexibility for sample sources such as buccal swabs, blood, bones and teeth, while an input volume of 25 μl enhances support for degraded and inhibited samples. The 12-reaction kit includes master mixes for amplification, purification beads for cleanup and straightforward protocols featuring six safe stopping points.\u003c\/p\u003e\u003ch2\u003eApplications\u003c\/h2\u003e\u003cp\u003eFGG combines microarray genotyping or whole‑genome sequencing (WGS) methods of DNA profile generation with comparisons of genetic relatives in genealogy databases such as GEDmatch, the largest database of voluntarily submitted DNA profiles for forensic comparisons. Comparisons made in a database allow genealogists to construct a family tree using census records, vital records, obituaries and newspaper archives, then trace the source of the DNA through the family tree.\u003c\/p\u003e\n\u003cp\u003eMicroarray and WGS-based methods cannot support the full spectrum of biological samples associated with forensic cases. These samples are often degraded or inhibited due to source material age or environmental exposure, resulting in low‑quality data that limits FGG. Microarrays and WGS also produce large amounts of medically relevant single nucleotide polymorphism (SNP) data that are not applicable to forensic applications, raising concerns about genetic data privacy and usage. The ForenSeq Kintelligence Kit is the only FGG assay fit for forensic purpose. Designed for sequencing on the National DNA Index System (NDIS)‑approved MiSeq FGx Sequencing System, data analysis in Universal Analysis Software (UAS), together with long‑range kinship analysis in GEDmatch PRO, ForenSeq Kintelligence and a Verogen STR assay can take you from DNA to a confirmed identity.\u003c\/p\u003e\u003ch2\u003eSoftware\u003c\/h2\u003e\u003cp\u003eThe end-to-end workflow of the ForenSeq Kintelligence Kit is based on the established ForenSeq process, enabling a diverse range of DNA analysis on a single, proven platform. The ForenSeq Kintelligence Kit links seamlessly with the ForenSeq Kintelligence Analysis Module in UAS for rapid data assessment and single-click report generation.\u003c\/p\u003e\u003ch2\u003eDocuments\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/validationandtechnicaldocument\/qpro-6696-ti-hid-forenseq-kintelligencekit-0424-ww\" target=\"_blank\" rel=\"noopener\"\u003eForenSeq Kintelligence Kit\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/kithandbookandprotocol\/forenseq-kintelligence-reference-guide-vd2020053-c\" target=\"_blank\" rel=\"noopener\"\u003eForenSeq Kintelligence Kit Reference Guide\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/scientificdocument\/qpro-5864-spos-hid-radecke-kintelligencevswgs-0224-ww-gedmatchpro\" target=\"_blank\" rel=\"noopener\"\u003eComparison of ForenSeq Kintelligence and Whole Genome Sequencing in searching for relatives in GEDmatch PRO\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/ebook.qiagen.com\/books\/muhf\/\" target=\"_blank\" rel=\"noopener\"\u003eIntegrated workflows for sexual assault analysis: Reliable forensic workflows for complex sexual assault evidence\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/brochureandguide\/qpro-5317-bro-hid-figgforle-1023-ww\" target=\"_blank\" rel=\"noopener\"\u003eA Law Enforcement Guide to Forensic Investigative Genetic Genealogy\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/brochureandguide\/prom-19028-001-1125732-fly-hid-ngs-0821-ww\" target=\"_blank\" rel=\"noopener\"\u003eA new horizon of human identification possibilities with NGS\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/brochureandguide\/qpro-11254-bro-hid-ngs-in-hid-0825-ww\" target=\"_blank\" rel=\"noopener\"\u003eReimagining Human Identification\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/brochureandguide\/qpro-7424-snedecor-synopsis-whitepaper-v4-lr\" target=\"_blank\" rel=\"noopener\"\u003eSynopsis of Snedecor\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eOrdering Information\u003c\/h2\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eCat. no.\u003c\/th\u003e\n\u003cth\u003eProduct\u003c\/th\u003e\n\u003cth\u003eContents\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\u003ctr\u003e\n\u003ctd\u003eV16000120\u003c\/td\u003e\n\u003ctd\u003eVerogen ForenSeq Kintelligence Kit\u003c\/td\u003e\n\u003ctd\u003eIncludes all the required reagents to prepare up to 12 low-quality forensic samples for forensic genetic genealogy\u003c\/td\u003e\n\u003c\/tr\u003e\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003e\u003cem\u003eThe Verogen ForenSeq Kintelligence Kit is intended for molecular biology applications in forensic, human identity, and paternity testing. This product is not intended for diagnosis, prevention, or treatment of a disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"QIAGEN","offers":[{"title":"Default Title","offer_id":46798469234767,"sku":"V16000120","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/1_5_WebFullSizeImage_7fc8a1c7-e14d-4ce8-aa2c-bdcde88c71c1.jpg?v=1789653406"},{"product_id":"qiagen-forenseq-kintelligence-ht-kit-v16000190","title":"ForenSeq Kintelligence HT Kit","description":"\u003cp\u003eForenSeq Kintelligence HT is the first targeted sequencing workflow designed for unidentified persons and remains or large-scale kinship projects. Targeting 10,230 SNP markers specifically curated for kinship determination, the assay is optimized to work with challenging samples such as bones. Leveraging the unique dual index (UDI) plate allows the library preparation workflow processing of up to 96 postmortem (PM) or antemortem (AM) samples before moving on to sequencing.\u003c\/p\u003e\n\u003cp\u003e \u003cbr\u003eThe ForenSeq Kintelligence HT workflow enables a higher level of multiplexing that balances throughput with the closer kinship determinations typically required for unidentified persons and remains. Detect at least third-degree kinship with 100% sensitivity and specificity when sequencing up to 12 postmortem samples or 36 antemortem samples per MiSeq FGx run. Analyze data in the Universal Analysis Software (UAS) using the preconfigured ForenSeq Kintelligence HT Analysis Method. Utilize the new UAS database exclusively for Kintelligence HT featuring local database storage, kinship comparison of postmortem to antemortem samples, and likelihood ratios for relationship comparisons.\u003c\/p\u003e\u003cp\u003eKit includes all the required reagents to prepare libraries from unidentified persons and remains samples\u003c\/p\u003e\u003ch2\u003eFeatures\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTargets 10,230 SNP markers explicitly curated for identification of unidentified persons and remains\u003c\/li\u003e\n\u003cli\u003eOvercomes challenges with bone samples with optimized PCR buffer\u003c\/li\u003e\n\u003cli\u003eUnique dual index (UDI) plate facilitates simple manual or automated transfer of the index adapters\u003c\/li\u003e\n\u003cli\u003eUp to 12 postmortem and 36 antemortem samples sequenced simultaneously to reach third degree relatives\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003ePerformance\u003c\/h2\u003e\u003cp\u003eThe ForenSeq Kintelligence HT kit is the first forensic assay to combine high throughput targeted SNP sequencing and local kinship analysis database for the large-scale identification of human remains. The fully integrated workflow includes optimized chemistry for highly degraded and contaminated samples, higher level multiplexing that balances throughput with closer kinship determinations, and a fit-for-purpose analysis software and kinship database that can be used  on a local database to maintain the privacy of the families concerned.\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003eForenSeq Kintelliegnce HT has optimized workflows for both postmortem (PM) and antemortem samples (AM) with sequencing capabilities up to 12 PM libraries and 36 AM libraries obtaining at least third degree relationship.\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003eHigh throughput, fit for purpose workflow:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eKinship power beyond STRs\u003cbr\u003eReliably determine relationships out to the third degree, even with degraded samples.\u003c\/li\u003e\n\u003cli\u003eSensitive solution for low input, low quality samples\u003cbr\u003eSequence compromised samples on a forensically validated system for easily accessible results.\u003c\/li\u003e\n\u003cli\u003eA local database for kinship analysis\u003cbr\u003ePair two familiar workflows, ForenSeq and GEDmatch PRO algorithms for kinship testing\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eFeature\u003c\/th\u003e\n\u003cth colspan=\"2\"\u003eDetails\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eKit configuration\u003c\/td\u003e\n\u003ctd colspan=\"2\"\u003e96 reactions\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eNumber of SNPs\u003c\/td\u003e\n\u003ctd colspan=\"2\"\u003e10,230\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMean amplicon size\u003c\/td\u003e\n\u003ctd colspan=\"2\"\u003e\u0026lt; 150 bp\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTotal library prep time\u003c\/td\u003e\n\u003ctd colspan=\"2\"\u003e10 hours\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eHands-on library prep time\u003c\/td\u003e\n\u003ctd colspan=\"2\"\u003e\u0026lt; 3 hours\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eSequencing time\u003c\/td\u003e\n\u003ctd colspan=\"2\"\u003e28 hours\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eSample type tested\u003c\/td\u003e\n\u003ctd colspan=\"2\"\u003eBlood, bone, buccal swabs, rooted hair, teeth, and semen\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e \u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003eAntemortem samples\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003ePostmortem samples\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eRecommended input\u003c\/td\u003e\n\u003ctd\u003e1 ng\u003c\/td\u003e\n\u003ctd\u003e500pg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMultiplexing capacity\u003c\/td\u003e\n\u003ctd\u003e36 libraries per run\u003c\/td\u003e\n\u003ctd\u003e12 libraries per run\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003ch2\u003ePrinciple\u003c\/h2\u003e\u003cp\u003eA robust PCR and primer design enables a single SNP multiplex, maximising kinship power. The small average amplicon size of \u0026lt; 150 bp improves amplification efficiency and facilitates recovery and analysis of degraded DNA. Additionally, the ForenSeq Kintelligence HT Kit includes 96 unique dual index (UDI) adapters, which attach unique identifying sequences to each end of the library for optimum data recovery.\u003c\/p\u003e\n\u003cp\u003eForenSeq Kintelligence HT queries 10,230 SNPs carefully selected to maximise kinship power.\u003c\/p\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eCategory\u003c\/td\u003e\n\u003ctd\u003eNumber of SNPs\u003c\/td\u003e\n\u003ctd\u003ePercentage of total\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAncestry SNPs\u003c\/td\u003e\n\u003ctd\u003e56\u003c\/td\u003e\n\u003ctd\u003e0,5%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eIdentity SNPs\u003c\/td\u003e\n\u003ctd\u003e94\u003c\/td\u003e\n\u003ctd\u003e1%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eKinship SNPs\u003c\/td\u003e\n\u003ctd\u003e9867\u003c\/td\u003e\n\u003ctd\u003e96%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePhenotype SNPs*\u003c\/td\u003e\n\u003ctd\u003e22\u003c\/td\u003e\n\u003ctd\u003e0,2%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eX-SNPs\u003c\/td\u003e\n\u003ctd\u003e106\u003c\/td\u003e\n\u003ctd\u003e1,2%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eY-SNPs\u003c\/td\u003e\n\u003ctd\u003e85\u003c\/td\u003e\n\u003ctd\u003e0,9%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e*Two SNPs overlap the ancestry and phenotype categories and are counted in the phenotype category only.\u003c\/p\u003e\n\u003cp\u003eThe ForenSeq Kintelligence HT Kit utilizes the same SNPs found in the original ForenSeq Kintelligence Kit, including the 9867 kinship SNPS, as well as all biogeographical ancestry, identity and phenotype SNPs validated for investigative lead generation. Also included are informative Y-SNPs and X-SNPs to help with lineage and biological sex determination, respectively.\u003c\/p\u003e\n\u003cp\u003eThese SNPs overlap with relevant markers in the Illumina Infinium CytoSNP-850K BeadChip and Infinium Global Screening Array and are cross referenced against the Genome Aggregation Database (gnomAD) v3.0 and Single Nucleotide Polymorphism database (dbSNP) v151 for robust performance across global populations. Importantly, ForenSeq Kintelligence HT excludes the SNPs with known medical associations or low minor allele frequencies to limit privacy concerns and protect genetic health data.\u003c\/p\u003e\n\u003cp\u003eAn optimized buffer system tolerates a range of inhibitors commonly found in forensic samples, such as calcium, indigo and humic acid, generating a \u0026gt; 98% call rate. Assay design provides a high level of process integrity and data quality so you can trust the analysis of even the most challenging forensic samples.\u003c\/p\u003e\u003ch2\u003eProcedure\u003c\/h2\u003e\u003cp\u003eForenSeq Kintelligence HT inputs are compatible with DNA extraction methods common in forensic laboratories. Library preparation leverages the same chemistry backbone that is foundational to the ForenSeq library prep portfolio. ForenSeq Kintelligence HT reagents enable preparation of up to 96 dual-indexed, human-specific libraries in 10 hours, with \u0026lt; 3 hours of hands-on time. Pooling libraries recommendation for sequencing are 12 PM samples or 36 AM samples.\u003c\/p\u003e\n\u003cp\u003eSequencing is completed in 28 hours and analysis in 1 hour, including upload to the local UAS database for kinship and likelihood analysis. The fully integrated NGS workflow delivers results. In addition to providing streamlined library prep that includes normalization, the ForenSeq chemistry offers a high degree of flexibility for sample sources such as buccal swabs, blood, bones and teeth. The 96-reaction kit includes master mixes for amplification, purification beads for cleanup and is supplied with straightforward protocols, featuring six safe stopping points.\u003c\/p\u003e\u003ch2\u003eApplications\u003c\/h2\u003e\u003cp\u003eThe ForenSeq Kintelligence HT Kit is the first forensic assay to combine high throughput targeted SNP sequencing and local kinship analysis for the identification of human remains in mass disaster or large-scale kinship projects. The fully integrated workflow includes optimized chemistry for highly degraded and contaminated samples and fit for purpose analysis software with a local kinship database. Library multiplexing recommendations balance throughput with the degree of relationship requirements.\u003c\/p\u003e\u003ch2\u003eSoftware\u003c\/h2\u003e\u003cp\u003eAs with all human identification scenarios, protection of genetic data from victims and families is important. Database access should be controlled for legislative and ethical reasons. The ForenSeq Kintelligence HT workflow includes the ability to create a private database within the UAS and built-in analysis tools repurposed from GEDmatch PRO to maintain sensitive information within a forensic environment.\u003c\/p\u003e\n\u003cp\u003eSamples processed with the ForenSeq Kintelligence HT Kit are analzyed using the UAS Kintelligence HT analysis module where users can view data and make edits if needed. Sample results are then accessable in the UAS database where kinship comparisons between two samples can be made utilizing the Query feature. When a user initiates a Query, an unknown sample(s) and a reference sampe(s) are compared in a pairwise manner. A range of metrics are displayed including shared cM, longest segment and kingship coefficient, allowing the user to make a determination of pedigree. Likelihood ratios are calculated for the compared samples when a specific relationship has been selected.\u003c\/p\u003e\u003ch2\u003eDocuments\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/validationandtechnicaldocument\/qpro-6310-ti-hid-kintelligence-ht-kit-0324-ww\" target=\"_blank\" rel=\"noopener\"\u003eForenSeq Kintelligence HT Kit\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/kithandbookandprotocol\/hb-3549-001-hb-forenseq-kintelligence-ht-0324-ww\" target=\"_blank\" rel=\"noopener\"\u003eForenSeq Kintelligence HT Kit Handbook\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/usermanual\/hb-3563-001-ug-uas-kintelligence-ht-0324-ww\" target=\"_blank\" rel=\"noopener\"\u003eUniversal Analysis Software User Guide for Kintelligence HT Module\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/brochureandguide\/qpro-5317-bro-hid-figgforle-1023-ww\" target=\"_blank\" rel=\"noopener\"\u003eA Law Enforcement Guide to Forensic Investigative Genetic Genealogy\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/brochureandguide\/qpro-11254-bro-hid-ngs-in-hid-0825-ww\" target=\"_blank\" rel=\"noopener\"\u003eReimagining Human Identification\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/validationandtechnicaldocument\/qpro-4484-ti-hid-figg-technologies-0224-ww\" target=\"_blank\" rel=\"noopener\"\u003eForensic Investigative Genetic Genealogy\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/scientificdocument\/qpro-5864-spos-hid-radecke-kintelligencevswgs-0224-ww-gedmatchpro\" target=\"_blank\" rel=\"noopener\"\u003eComparison of ForenSeq Kintelligence and Whole Genome Sequencing in searching for relatives in GEDmatch PRO\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eOrdering Information\u003c\/h2\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eCat. no.\u003c\/th\u003e\n\u003cth\u003eProduct\u003c\/th\u003e\n\u003cth\u003eContents\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\u003ctr\u003e\n\u003ctd\u003eV16000190\u003c\/td\u003e\n\u003ctd\u003eForenSeq Kintelligence HT Kit\u003c\/td\u003e\n\u003ctd\u003eKit includes all the required reagents to prepare libraries from unidentified persons and remains samples\u003c\/td\u003e\n\u003c\/tr\u003e\u003c\/tbody\u003e\n\u003c\/table\u003e","brand":"QIAGEN","offers":[{"title":"Default Title","offer_id":46798469496911,"sku":"V16000190","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/1_5_WebFullSizeImage_7fc8a1c7-e14d-4ce8-aa2c-bdcde88c71c1.jpg?v=1789653406"},{"product_id":"qiagen-forenseq-imagen-kit-v16000189","title":"Verogen ForenSeq Imagen Kit","description":"\u003cp\u003eThe Verogen ForenSeq Imagen kit is a library preparation kit offering two different primer mixes that allow the user to evaluate phenotypic SNPs with or without biogeographical ancestry. The ForenSeq Imagen workflow is a fully validated DNA-to-data workflow specifically designed for forensic genomics applications. The kit relies on established, peer-reviewed SNP marker sets that have been identified and tested by the forensic community.\u003c\/p\u003e\n\u003cp\u003eThe Verogen ForenSeq Imagen Kit is an optimized solution for operational forensic labs considering implementing an NGS-based lead generation workflow.\u003c\/p\u003e\u003cp\u003eIncludes the required reagents to process up to 96 samples simultaneously for phenotypic and biogeographical ancestry information to generate comprehensive DNA profiles\u003c\/p\u003e\u003ch2\u003eFeatures\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eEvaluation of phenotypic SNPs with or without biogeographical ancestry\u003c\/li\u003e\n\u003cli\u003eWorkflow tailored to integrate in operational forensic laboratories\u003c\/li\u003e\n\u003cli\u003eInteroperable and scalable with preconfigured reports for upload to third party tools\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003ePerformance\u003c\/h2\u003e\u003cp\u003eThe ForenSeq Imagen Kit offers the following features:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eA concentrated primer mix for increased sample input volume\u003c\/li\u003e\n\u003cli\u003eSimultaneous preparation of up to 96 libraries in one plate; each library is a collection of amplified DNA fragments from one sample\u003c\/li\u003e\n\u003cli\u003eAssay designed to maximize DNA profiles with degraded and low-input samples by generating short amplicons with Unique Dual Indices (UDIs)\u003c\/li\u003e\n\u003cli\u003eBuffer system to support inhibited forensic samples\u003c\/li\u003e\n\u003cli\u003eTwo primer mixes to generate insights based on existing and emerging regional regulation \n\u003cul\u003e\n\u003cli\u003eDPME – Amplifies SNP targets for the prediction of skin, hair and eye color, also referred to as external visible characteristics (EVC)\u003c\/li\u003e\n\u003cli\u003eDPMF (Geo) – Amplifies SNP targets for the prediction of EVCs in DPME and biogeographical ancestry (BGA) markers\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eBoth primer sets encompass 41 SNPs for the phenotypic estimations that include 22 SNPs for the estimation of hair color, 6 SNPs for the estimation of eye color, 36 markers for the estimation of skin color, with some SNPs common to more than one phenotype. Both primer sets encompass 14 Y-SNPs to enable robust estimation of biological sex. In addition, 56 SNPs for the estimation of biogeographic ancestry are included in one of the primer sets. Labs have the flexibility to use either of the two primer sets based on the regulatory approaches associated with their geography.\u003c\/p\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eFeature\u003c\/td\u003e\n\u003ctd\u003eDetails\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eSample type\u003c\/td\u003e\n\u003ctd\u003eExtracted gDNA from a range of common forensic sample types:\u003cbr\u003ebuccal swab lysate, bones, blood, teeth and FTA card \u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eRecommended input for gDNA\u003c\/td\u003e\n\u003ctd\u003e32 pg–1 ng per sample\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eRecommended input for FTA card punch\u003c\/td\u003e\n\u003ctd\u003e1.2 mm per sample\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eRecommended multiplexing capacity\u003c\/td\u003e\n\u003ctd\u003e8–96 libraries per run\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eNumber of primer mixes\u003c\/td\u003e\n\u003ctd\u003e2: DPME and DPMF (Geo)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePrimer mix content\u003c\/td\u003e\n\u003ctd\u003eDPME: 22 hair SNPs, 6 eye color SNPs, 36 skin color SNPs \u003cbr\u003eand 14 Y-SNPs (total of 55 SNPs)\u003cbr\u003eDPMF (Geo): 22 hair SNPs, 6 eye color SNPs, 36 skin color SNPs, \u003cbr\u003e56 BGA SNPs and 14 Y-SNPs (total of 111 SNPs)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eShort amplicon detection\u003c\/td\u003e\n\u003ctd\u003eHigh concentration of markers \u0026lt;150 bp\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTotal library prep time\u003c\/td\u003e\n\u003ctd\u003e7 hours and 15 minutes\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eHands-on time\u003c\/td\u003e\n\u003ctd\u003e1 hour and 30 minutes\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTotal sequencing time\u003c\/td\u003e\n\u003ctd\u003e~18 hours with the Verogen MiSeq FGx Reagent Micro Kit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\u003ch2\u003ePrinciple\u003c\/h2\u003e\u003cp\u003eThe Verogen ForenSeq Imagen Kit generates dual-indexed libraries for sequencing. Each sample is combined with a primer mix that contains a pair of tagged oligos for each target sequence. PCR cycles link the tags to copies of each target, forming DNA templates consisting of the regions of interest flanked by universal primer binding sequences. The tags are then used to attach index adapters and the resulting library is amplified, purified, and pooled for sequencing.\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003eThe table provides a summary of the number of markers associated with both primer sets in the Verogen ForenSeq Imagen Kit.\u003c\/p\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eSNP category\u003c\/th\u003e\n\u003cth\u003eNumber of markers\u003c\/th\u003e\n\u003cth\u003eAmplicon size range\u003cbr\u003e(bp)\u003c\/th\u003e\n\u003cth colspan=\"2\"\u003eIncluded in DNA primer\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e \u003c\/td\u003e\n\u003ctd\u003e \u003c\/td\u003e\n\u003ctd\u003e \u003c\/td\u003e\n\u003ctd\u003eMix E\u003c\/td\u003e\n\u003ctd\u003eMix F\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eY-SNPs*\u003c\/td\u003e\n\u003ctd\u003e14\u003c\/td\u003e\n\u003ctd\u003e88–130\u003c\/td\u003e\n\u003ctd\u003eYes\u003c\/td\u003e\n\u003ctd\u003eYes\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePhenotypic SNPs\u003c\/td\u003e\n\u003ctd\u003e41\u003c\/td\u003e\n\u003ctd\u003e69–227\u003c\/td\u003e\n\u003ctd\u003eYes\u003c\/td\u003e\n\u003ctd\u003eYes\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eHair color\u003c\/td\u003e\n\u003ctd\u003e22\u003c\/td\u003e\n\u003ctd\u003e92–227\u003c\/td\u003e\n\u003ctd\u003eYes\u003c\/td\u003e\n\u003ctd\u003eYes\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eEye color\u003c\/td\u003e\n\u003ctd\u003e6\u003c\/td\u003e\n\u003ctd\u003e73–119\u003c\/td\u003e\n\u003ctd\u003eYes\u003c\/td\u003e\n\u003ctd\u003eYes\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eSkin color\u003c\/td\u003e\n\u003ctd\u003e36\u003c\/td\u003e\n\u003ctd\u003e69–213\u003c\/td\u003e\n\u003ctd\u003eYes\u003c\/td\u003e\n\u003ctd\u003eYes\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBiogeographical** ancestry SNPs\u003c\/td\u003e\n\u003ctd\u003e56\u003c\/td\u003e\n\u003ctd\u003e67–200\u003c\/td\u003e\n\u003ctd\u003eNo\u003c\/td\u003e\n\u003ctd\u003eYes\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e* 4 SNPs overlap across eye, skin and hair color phenotypes; 13 SNPs overlap across hair and skin color phenotypes; and 2 SNPs overlap across eye and skin color phenotypes.\u003cbr\u003e** Only available in the EVC+BGA SNP panel (DPMF-Geo).\u003c\/p\u003e\u003ch2\u003eProcedure\u003c\/h2\u003e\u003cp\u003eThe ForenSeq Imagen workflow, comprising the ForenSeq Imagen kit, the MiSeq FGx Sequencing System with the MiSeq FGx Reagent Micro kit, and the ForenSeq Imagen analysis methods in the Universal Analysis Software (UAS), is a fully validated DNA-to-data workflow specifically designed for forensic genomics applications (see figure Verogen ForenSeq Imagen Kit workflow). \u003c\/p\u003e\n\u003cp\u003ePrepare the ForenSeq Imagen assay with DPME for External Visible Characteristics (EVC) and Appearance SNPs or DPMF (Geo) for EVC and Biogeographical Ancestry (BGA) SNPs.  \u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003eSequence with the MiSeq FGx Sequencing System using the MiSeq FGx Reagent Micro Kit.\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003eAnalyze with dedicated analysis modules preconfigured for Imagen and Imagen Geo analysis methods.\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003eBatch-download multiple report types from Imagen and Imagen Geo. Phenotype analysis reports are compatible with the HIrisPlex-S web application.\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003eUpload the phenotype report to the HIrisPlex-S web application for estimations.\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003eGenerate your reports. The data is reformatted in accessible form with the I-HAT macro tool hosted on the Verogen Data Analysis Server.\u003c\/p\u003e\u003ch2\u003eApplications\u003c\/h2\u003e\u003cp\u003eForensic DNA Phenotyping (FDP) can predict externally visible characteristics from DNA traces at a crime scene. FDP analysis can help focus police investigations with information on an unknown perpetrator when standard DNA profiling fails to inform on identification. \u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003eThe simple Verogen ForenSeq Imagen Kit plate-based assay is part of an integrated FDP workflow that sequences libraries on the MiSeq FGx Sequencing System and analyzes data in Universal Analysis Software (UAS). Seamless report integration with 3rd party software such as HIrisPlex-S allows users to access enhanced lead generation insights.\u003c\/p\u003e\u003ch2\u003eSoftware\u003c\/h2\u003e\u003cp\u003eData generated by the ForenSeq Imagen kit is optimized for analysis using the Universal Analysis Software. Two fit-for-purpose analysis methods enable labs to analyze data from the DPME or DPMF (Geo) primer mixes separately. The UAS generates SNP reports that can be uploaded to the HIrisPlex-S web application for predictions powered by solutions described in multiple peer-reviewed publications. \u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003eTo allow easy interpretation of complex statistical information, reports from the HIrisPlex-S web application can be parsed by the Imagen-HIrisPlex-S Analysis Tool (I-HAT) application on the UAS data server. The I-HAT macro generates human-readable reports that summarize the predictions and probabilities associated with typed SNPs. \u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003eAutomation of the lab workflow allows labs to onboard the entire ForenSeq Imagen workflow from lab to report with confidence. Robust out-of-the-box thresholds and settings allow easy validation and implementation. Rich data visualization capabilities enable labs to quickly gauge the quality of their sequencing run and SNP calls. Extensive filtering and sorting capabilities enable manual review of markers that require inspection.\u003c\/p\u003e\u003ch2\u003eDocuments\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/validationandtechnicaldocument\/qpro-6234-ti-hid-forenseq-imagenkit-1224-ww\" target=\"_blank\" rel=\"noopener\"\u003eForenSeq Imagen Kit\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/validationandtechnicaldocument\/forenseq-imagen-materials-epcr1-vd2022012-a\" target=\"_blank\" rel=\"noopener\"\u003eForenSeq Imagen Kit with the ForenSeq Enhanced PCR1 Buffer System\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/kithandbookandprotocol\/hb-3614-001-hb\" target=\"_blank\" rel=\"noopener\"\u003eForenSeq Imagen Kit Handbook for PrepStation\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/kithandbookandprotocol\/forenseq-imagen-reference-guide-pcr1-vd2022008-a\" target=\"_blank\" rel=\"noopener\"\u003eForenSeq Imagen Kit Reference Guide\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/kithandbookandprotocol\/forenseq-imagen-reference-guide-epcr1-vd2022011-a\" target=\"_blank\" rel=\"noopener\"\u003eForenSeq Imagen Kit with the Enhanced PCR1 Buffer System Reference Guide\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/analysissoftware\/universal-analysis-software-v2-reference-guide-imagen-vd2022014-reva\" target=\"_blank\" rel=\"noopener\"\u003eUniversal Analysis Software Imagen Module V2 Reference Guide # VD2022014 Rev. A August 2022\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/brochureandguide\/prom-19028-001-1125732-fly-hid-ngs-0821-ww\" target=\"_blank\" rel=\"noopener\"\u003eA new horizon of human identification possibilities with NGS\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.qiagen.com\/us\/resources\/brochureandguide\/qpro-11254-bro-hid-ngs-in-hid-0825-ww\" target=\"_blank\" rel=\"noopener\"\u003eReimagining Human Identification\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eOrdering Information\u003c\/h2\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eCat. no.\u003c\/th\u003e\n\u003cth\u003eProduct\u003c\/th\u003e\n\u003cth\u003eContents\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\u003ctr\u003e\n\u003ctd\u003eV16000189\u003c\/td\u003e\n\u003ctd\u003eVerogen ForenSeq Imagen Kit\u003c\/td\u003e\n\u003ctd\u003eIncludes the required reagents to process up to 96 samples simultaneously for phenotypic and biogeographical ancestry information to generate comprehensive DNA profiles\u003c\/td\u003e\n\u003c\/tr\u003e\u003c\/tbody\u003e\n\u003c\/table\u003e\u003cp\u003e\u003cem\u003eThe Verogen ForenSeq Imagen Kit is intended for molecular biology applications in forensic, human identity, and paternity testing. This product is not intended for diagnosis, prevention, or treatment of a disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"QIAGEN","offers":[{"title":"Default Title","offer_id":46798469464143,"sku":"V16000189","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/1_5_WebFullSizeImage_7fc8a1c7-e14d-4ce8-aa2c-bdcde88c71c1.jpg?v=1789653406"}],"url":"https:\/\/www.danyel.co.il\/collections\/qiagen.oembed","provider":"danyel biotech","version":"1.0","type":"link"}