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href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-17788-pdf\"\u003eInstructions for use (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Cytiva","offers":[{"title":"SH30852.01 \/ 100 mL","offer_id":45982128439375,"sku":"SH30852.01","price":74.0,"currency_code":"ILS","in_stock":true},{"title":"SH30853.01 \/ 100 mL","offer_id":45982128472143,"sku":"SH30853.01","price":71.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/digi-23429-original-png_ffa67c47-3637-4f6c-982d-7ff9768796fb.png?v=1785958601"},{"product_id":"hyclone-defined-fetal-bovine-serum-fbs-united-states-origin-sh30070-03ih25-40","title":"HyClone™ Defined Fetal Bovine Serum (FBS), United States Origin","description":"\u003cp\u003eOur highest quality FBS, HyClone™ US-origin Defined FBS is proprietary serial 40 nm-filtered, virus-tested to meet Title 9 CFR (Code of Federal Regulations), with an extensive biochemical profile.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eWell-defined: assay results for over 50 components, with additional testing available.\u003c\/li\u003e\n\u003cli\u003eUS origin: sourced and processed in the United States with complete traceability to origin.\u003c\/li\u003e\n\u003cli\u003eUltra-low endotoxin: ≤ 5 EU\/mL endotoxin for reduced research and production risk.\u003c\/li\u003e\n\u003cli\u003eSterile-filtered: proprietary serial 40 nm filter process.\u003c\/li\u003e\n\u003cli\u003ePost-filtration treatments: γ-irradiated and heat-inactivated FBS options also available.\u003c\/li\u003e\n\u003cli\u003eVirus-tested: broad virus panel testing in accordance with 9 CFR 113.53.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003ePurchase orders with specific lot requests, quoted reserves and\/or call off orders should be submitted through \u003ca href=\"\/support\/contact-us\"\u003eCustomer Service.\u003c\/a\u003e\u003c\/em\u003e\u003c\/p\u003e\n\n\u003cp\u003eFetal bovine serum (FBS) is a nutrient-rich cell culture supplement that is high in growth factors and low in antibodies, compared to non-fetal sera.\u003c\/p\u003e\n\n\u003cp\u003eDefined FBS for cell culture confidence and consistency\u003c\/p\u003e\n\n\u003cp\u003eHyClone™ Defined FBS is widely used by cell culturists who have a concern for viral contaminants and require an extensive biochemical profile. The final serum is assayed for over 50 components, including proteins, hormones, growth factors, metabolites, and nutrients important for cell culture. Assay results are included in the certificate of analysis and the biochemical assay list. Additional testing, including EMEA conformance testing, is also available.\u003c\/p\u003e\n\n\u003cp\u003eExceptionally low endotoxin levels\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin contamination is a significant concern when producing cell culture-derived products for use in humans or animals. The presence of endotoxin in cell cultures can also have adverse and unpredictable effects on cell growth, function and phenotype that can compromise research results. Our patented closed-system blood collection method and rigorous quality control testing ensure that HyClone™ Defined FBS contains ≤ 5 EU\/mL endotoxin and ≤ 15 mg\/dL hemoglobin. Low hemoglobin levels in the final product are an indication that extensive cell lysis has not occurred, confirming that the fetal blood has been handled appropriately during collection and transport.\u003c\/p\u003e\n\n\u003cp\u003eVirus-tested and quality-assured for reduced contamination risk\u003c\/p\u003e\n\n\u003cp\u003eHyClone™ Defined FBS is filtered through proprietary serial 40 nm (0.04 μm) pore size-rated filters, which are the most retentive filters used in commercial FBS production. This type of filtration is practical in reducing risk while maintaining high performance in cell growth.\u003c\/p\u003e\n\n\u003cp\u003eStudies demonstrate that this filtration regimen has no adverse effect on cell growth. Before dispensing, each lot of serum is pooled using true pool technology to ensure uniformity and consistency between bottles.\u003c\/p\u003e\n\n\u003cp\u003eThe final serum is virus-tested according to 9 CFR 113.53 to demonstrate that there are no detectable levels of specified viruses, pathogenic agents, and hemadsorbing agents. Robust sterility testing further confirms that the final product contains no detectable growth of bacteria or fungi (current USP) and no detectable mycoplasma.\u003c\/p\u003e\n\n\u003cp\u003ePost-filtration treatments for added process security\u003c\/p\u003e\n\n\u003cp\u003eGamma-irradiated and heat-inactivated FBS options are available to further reduce the risk of adventitious agents, particularly when manufacturing products for use in humans or animals. The irradiation process is validated to deliver a multiple validated dose ranges starting at a minimum dose of 25 kGy.\u003c\/p\u003e\n\n\u003cp\u003eRegulatory and supply chain security\u003c\/p\u003e\n\n\u003cp\u003eFor decades, Cytiva's HyClone™ premium bovine serum products have exceeded industry standards for quality, purity, and regulatory compliance. HyClone™ serum processes are traceability-certified by the International Serum Industry Association (ISIA). In addition, Cytiva has chosen to be an early adopter of scientific traceability by Oritain™ to prove the country of origin of their premium bovine serum products from the United States, Australia, and New Zealand. Premium bovine serum samples from different regions have been analyzed and Oritain™ has created a database of the unique ‘Origin Fingerprint’ that is exclusive to each country of origin. \u003ca href=\"https:\/\/oritain.com\/verified\/verified-partners\/cytiva\/\" target=\"_blank\"\u003eLearn more\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003eTemperature excursions happen, both in transport and on the bench. \u003ca href=\"\/solutions\/bioprocessing\/knowledge-center\/fetal-bovine-serum-storage-temperature\"\u003eStorage condition effects on fetal bovine serum for cell culture whitepaper\u003c\/a\u003e shows how HyClone™ serum maintain viable cell density and cell growth and stay within specification under various temperatures and timeframes.\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-17854-pdf\"\u003eData file (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-17789-pdf\"\u003eInstructions for use (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Cytiva","offers":[{"title":"50 mL (SH30070.01HI)","offer_id":45982128537679,"sku":"SH30070.01HI","price":613.0,"currency_code":"ILS","in_stock":true},{"title":"50 mL (SH30070.01)","offer_id":45982128570447,"sku":"SH30070.01","price":523.0,"currency_code":"ILS","in_stock":true},{"title":"100 mL (SH30070.02HI)","offer_id":45982128603215,"sku":"SH30070.02HI","price":1072.0,"currency_code":"ILS","in_stock":true},{"title":"100 mL (SH30070.02)","offer_id":45982128635983,"sku":"SH30070.02","price":884.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30070.03IH25-40)","offer_id":45982128668751,"sku":"SH30070.03IH25-40","price":4325.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30070.03IH30-45)","offer_id":45982128701519,"sku":"SH30070.03IH30-45","price":4325.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30070.03IR25-40)","offer_id":45982128734287,"sku":"SH30070.03IR25-40","price":3789.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30070.03IR30-45)","offer_id":45982128767055,"sku":"SH30070.03IR30-45","price":3789.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30070.03HI)","offer_id":45982128799823,"sku":"SH30070.03HI","price":3789.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30070.03)","offer_id":45982128832591,"sku":"SH30070.03","price":3688.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/digi-26812-original-png_ddac5794-6a17-4445-95ff-4a4148186458.png?v=1785958601"},{"product_id":"hyclone-super-low-igg-fetal-bovine-serum-fbs-us-origin-sh30898-03ih25-40","title":"HyClone™ Super Low IgG Fetal Bovine Serum (FBS), US origin","description":"\u003cp\u003eHyClone™ Super Low IgG Fetal Bovine Serum (FBS), US origin is designed for applications where extremely low levels of inherent bovine IgG are required. Super Low IgG FBS has been chromatographically treated to reduce IgG levels to less than 5 µg\/mL, while still retaining excellent cell growth properties.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSourced in the US\u003c\/li\u003e\n\u003cli\u003eComplete traceability is provided back to the original source, as certified by the International Serum Industry Association (ISIA).\u003c\/li\u003e\n\u003cli\u003e40 nm filtered\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003ePurchase orders with specific lot requests, quoted reserves, and\/or call-off orders should be submitted through \u003ca href=\"\/support\/contact-us\"\u003eCustomer Service\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003eAdditional treatments are available: HyClone™ FBS heat inactivated (HI) and HyClone™ FBS irradiated (IR). Additional testing, including EMEA-conforming testing, is also available.\u003c\/p\u003e","brand":"Cytiva","offers":[{"title":"50 mL","offer_id":45982128898127,"sku":"SH30898.01","price":590.0,"currency_code":"ILS","in_stock":true},{"title":"100 mL (SH30898.02HI)","offer_id":45982128930895,"sku":"SH30898.02HI","price":871.0,"currency_code":"ILS","in_stock":true},{"title":"100 mL (SH30898.02)","offer_id":45982128963663,"sku":"SH30898.02","price":767.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30898.03IH25-40)","offer_id":45982128996431,"sku":"SH30898.03IH25-40","price":3363.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30898.03IR25-40)","offer_id":45982129029199,"sku":"SH30898.03IR25-40","price":3313.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30898.03HI)","offer_id":45982129061967,"sku":"SH30898.03HI","price":3313.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30898.03)","offer_id":45982129094735,"sku":"SH30898.03","price":3206.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/69c2a45ee6724ce6b5869640310fc044_c0068a0c-cd59-4882-b332-109d471ad662.png?v=1785956229"},{"product_id":"hyclone-defined-fetal-bovine-serum-fbs-new-zealand-origin-sh31194-03hi","title":"HyClone™ Defined Fetal Bovine Serum (FBS), New Zealand Origin","description":"\u003cp\u003eOur highest quality FBS, HyClone™ NZ-origin Defined FBS is proprietary serial 40 nm-filtered, virus-tested to 9 CFR standard, and supplied with an extensive biochemical profile.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eWell-defined: assay results for over 50 components, with additional testing available\u003c\/li\u003e\n\u003cli\u003eNZ origin: sourced and processed in New Zealand with complete traceability to origin\u003c\/li\u003e\n\u003cli\u003eUltra-low endotoxin: ≤ 5 EU\/mL endotoxin for reduced research and production risk\u003c\/li\u003e\n\u003cli\u003eSterile-filtered: Proprietary serial 40 nm filter process\u003c\/li\u003e\n\u003cli\u003ePost-filtration treatments: γ-irradiated and heat-inactivated FBS options are available\u003c\/li\u003e\n\u003cli\u003eVirus-tested: broad virus panel testing in accordance with 9 CFR 113.53\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003ePurchase orders with specific lot requests, quoted reserves and\/or call off orders should be submitted through \u003ca href=\"\/support\/contact-us\"\u003eCustomer Service.\u003c\/a\u003e\u003c\/em\u003e\u003c\/p\u003e\n\n\u003cp\u003eFetal bovine serum (FBS) is a nutrient-rich cell culture supplement that is high in growth factors and low in antibodies, compared to non-fetal sera. \u003c\/p\u003e\n\n\u003cp\u003eDefined FBS for cell culture confidence and consistency\u003c\/p\u003e\n\n\u003cp\u003eHyClone™ Defined FBS is widely used by cell culturists who have a concern for viral contaminants and require an extensive biochemical profile. The final serum is assayed for over 50 components, including proteins, hormones, growth factors, metabolites, and nutrients important for cell culture. Assay results are included in the certificate of analysis and the biochemical assay list. Additional testing, including EMEA conformance testing, is also available.\u003c\/p\u003e\n\n\u003cp\u003eExceptionally low endotoxin levels\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin contamination is a significant concern when producing cell culture-derived products for use in humans or animals. The presence of endotoxin in cell cultures can also have adverse and unpredictable effects on cell growth, function and phenotype that can compromise research results. Our patented closed-system blood collection method and rigorous quality control testing ensure that HyClone™ defined FBS contains ≤ 5 EU\/mL endotoxin and ≤ 15 mg\/dL hemoglobin. Low hemoglobin levels in the final product are an indication that extensive cell lysis has not occurred, confirming that the fetal blood has been handled appropriately during collection and transport.\u003c\/p\u003e\n\n\u003cp\u003eVirus-tested and quality-assured for reduced contamination risk\u003c\/p\u003e\n\n\u003cp\u003eHyClone™ Defined FBS is filtered through proprietary serial 40 nm (0.04 μm) pore size-rated filters, which are the most retentive filters used in commercial FBS production. This type of filtration is practical in reducing risk while maintaining high performance in cell growth.\u003c\/p\u003e\n\n\u003cp\u003eStudies demonstrate that this filtration regimen has no adverse effect on cell growth. Before dispensing, each lot of serum is pooled using true pool technology to ensure uniformity and consistency between bottles.\u003c\/p\u003e\n\n\u003cp\u003eThe final serum is virus-tested according to 9 CFR 113.53 to demonstrate that there are no detectable levels of specified viruses, pathogenic agents, and hemadsorbing agents. Robust sterility testing further confirms that the final product contains no detectable growth of bacteria or fungi (current USP) and no detectable mycoplasma.\u003c\/p\u003e\n\n\u003cp\u003ePost-filtration treatments for added process security\u003c\/p\u003e\n\n\u003cp\u003eGamma-irradiated and heat-inactivated FBS options are available to further reduce the risk of adventitious agents, particularly when manufacturing products for use in humans or animals. The irradiation process is validated to deliver multiple validated dose ranges starting at 25 kGy\u003c\/p\u003e\n\n\u003cp\u003eRegulatory and supply chain security\u003c\/p\u003e\n\n\u003cp\u003eFor decades, Cytiva's HyClone™ premium bovine serum products have exceeded industry standards for quality, purity, and regulatory compliance. HyClone™ serum processes are traceability-certified by the International Serum Industry Association (ISIA). In addition, Cytiva has chosen to be an early adopter of scientific traceability by Oritain™ to prove the country of origin of their premium bovine serum products from the United States, Australia, and New Zealand. Premium bovine serum samples from different regions have been analyzed and Oritain has created a database of the unique ‘Origin Fingerprint’ that is exclusive to each country of origin. \u003ca href=\"https:\/\/oritain.com\/verified\/verified-partners\/cytiva\/\" target=\"_blank\"\u003eLearn more\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eTemperature excursions happen, both in transport and on the bench. \u003ca href=\"\/solutions\/bioprocessing\/knowledge-center\/fetal-bovine-serum-storage-temperature\"\u003eStorage condition effects on fetal bovine serum for cell culture whitepaper\u003c\/a\u003e shows how HyClone™ serum maintain viable cell density and cell growth and stay within specification under various temperatures and timeframes.\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-17854-pdf\"\u003eData file (PDF)\u003c\/a\u003e\u003c\/li\u003e\u003c\/ul\u003e","brand":"Cytiva","offers":[{"title":"50 mL (SH31194.01HI)","offer_id":45982129487951,"sku":"SH31194.01HI","price":559.0,"currency_code":"ILS","in_stock":true},{"title":"50 mL (SH31194.01)","offer_id":45982129520719,"sku":"SH31194.01","price":486.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH31194.03HI)","offer_id":45982129553487,"sku":"SH31194.03HI","price":3243.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH31194.03IR30-45)","offer_id":45982129586255,"sku":"SH31194.03IR30-45","price":3243.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH31194.03)","offer_id":45982129619023,"sku":"SH31194.03","price":2921.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/hdhhqFFjTUqCZzVeXJsg7g-original-png_184b739e-3d32-4622-821f-05f4bbae8a37.png?v=1785958607"},{"product_id":"hyclone-characterized-fetal-bovine-serum-au-origin-sh30084-03ih25-40","title":"HyClone™ Characterized Fetal Bovine Serum, AU Origin","description":"\u003cp\u003eThis premium HyClone™ Fetal Bovine Australian-origin Serum is well-characterized, triple 100 nm filtered, virus-tested to 9 CFR standard, and traceability-certified (ISIA, Oritain).\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eAustralian origin: benefit from Australian husbandry methods and certified traceability\u003c\/li\u003e\n\u003cli\u003eCharacterized: assayed for a variety of critical components and biochemical characteristics\u003c\/li\u003e\n\u003cli\u003eEndotoxin-tested: certificate of analysis confirms ≤ 10 EU\/mL endotoxin\u003c\/li\u003e\n\u003cli\u003eTriple-filtered: serial Triple 100 nm pore size-rated filtering for reliable microbial depletion\u003c\/li\u003e\n\u003cli\u003ePost-filtration treatments: γ-irradiated and heat-inactivated FBS options also available\u003c\/li\u003e\n\u003cli\u003eVirus-tested: broad virus panel testing in accordance with 9 CFR 113.53\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003ePurchase orders with specific lot requests, quoted reserves and\/or call off orders should be submitted through \u003ca href=\"\/support\/contact-us\"\u003eCustomer Service.\u003c\/a\u003e\u003c\/em\u003e\u003c\/p\u003e\n\n\u003cp\u003eFetal bovine serum (FBS) is a nutrient-rich cell culture supplement that is high in growth factors and low in antibodies, compared to non-fetal sera.\u003c\/p\u003e\n\n\u003cp\u003eWhy choose HyClone\u003csup\u003eTM\u003c\/sup\u003e Australian Origin FBS?\u003c\/p\u003e\n\n\u003cp\u003eHyClone Australian Origin serum is sourced from Australian abattoirs approved by the U.S. Department of Agriculture (USDA) or Australian Quarantine and Inspection Service (AQIS). The Australian methods of animal husbandry exhibit excellent animal nutrition and healthcare. Australia is an isolated continent, thus making animal disease and control management easier than in most areas of the world.\u003c\/p\u003e\n\n\u003cp\u003eCharacterized FBS for cell culture\u003c\/p\u003e\n\n\u003cp\u003eHyClone Characterized FBS is an excellent alternative to more expensive defined sera, and meets the requirements of most discriminating FBS users. The final serum is assayed for important proteins, hormones, growth factors, metabolites, and nutrients that support healthy cell cultures. Assay results are included in the certificate of analysis and biochemical assay list. Additional testing, including EMEA-conforming testing, is also available.\u003c\/p\u003e\n\n\u003cp\u003eHave Confidence in Security of Supply with Secondary Sourcing\u003c\/p\u003e\n\n\u003cp\u003eFetal Bovine Serum from a single origin may be limited, so it’s important to qualify FBS products from other countries to increase your security of supply. HyClone Characterized FBS from United States (US), New Zealand (NZ) and Australia (AUS) have been evaluated and tested to show equivalent performance. \u003ca href=\"\/solutions\/bioprocessing\/knowledge-center\/fbs-origin-equivalence-study\"\u003eRead our full study\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003cp\u003eBacterial endotoxin-tested\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin contamination is a significant concern in research and manufacturing, especially when producing cell culture-derived products for use in humans or animals. The presence of endotoxin in cell cultures can also have adverse and unpredictable effects on cell growth, function and phenotype that can compromise research results. Our patented closed-system blood collection method and rigorous quality control testing ensure that HyClone Characterized FBS meets industry standards of ≤ 10 EU\/mL endotoxin. The final product also contains ≤ 25 mg\/dL hemoglobin, which is an indicator of appropriate handling during collection and transport.\u003c\/p\u003e\n\n\u003cp\u003eVirus-tested and quality-assured for reduced contamination risk\u003c\/p\u003e\n\n\u003cp\u003eHyClone Characterized FBS is triple-filtered through serial 100 nm (0.10 μm) pore size-rated filters, which has become an industry standard for cell culture grade FBS. Before dispensing, each lot of serum is pooled using true pool technology to minimize variability from bottle to bottle.\u003c\/p\u003e\n\n\u003cp\u003eThe final serum is virus-tested according to 9 CFR 113.53 to demonstrate that there are no detectable levels of specified viruses, pathogenic agents, and hemadsorbing agents. Robust sterility testing further confirms that the final product contains no detectable growth of bacteria or fungi (current USP) and no detectable mycoplasma.\u003c\/p\u003e\n\n\u003cp\u003ePost-filtration treatments for added process security\u003c\/p\u003e\n\n\u003cp\u003eGamma-irradiated and heat-inactivated FBS options are available to further reduce the risk of adventitious agents, particularly when manufacturing products for use in humans or animals. The irradiation process is validated to deliver a minimum dose of 25 kGy.\u003c\/p\u003e\n\n\u003cp\u003eRegulatory and supply chain security\u003c\/p\u003e\n\n\u003cp\u003eFor decades, Cytiva's HyClone™ premium bovine serum products have exceeded industry standards for quality, purity, and regulatory compliance. HyClone™ serum processes are traceability traceability-certified by the International Serum Industry Association (ISIA) and, . Iin addition, Cytiva has chosen to be an early adopter of scientific traceability by Oritain to prove the country of origin of their premium bovine serum products from the United States, Australia and New Zealand. Premium bovine serum samples from different regions have been analyzed and Oritain has created a database of the unique ‘Origin Fingerprint’ that is exclusive to each country of origin. Learn more \u003ca href=\"https:\/\/oritain.com\/partners\/cytiva\" target=\"_blank\"\u003ehere\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003eTemperature excursions happen, both in transport and on the bench. \u003ca href=\"\/solutions\/bioprocessing\/knowledge-center\/fetal-bovine-serum-storage-temperature\"\u003eStorage condition effects on fetal bovine serum for cell culture whitepaper\u003c\/a\u003e shows how HyClone™ serum maintain viable cell density and cell growth and stay within specification under various temperatures and timeframes.\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-17665-pdf\"\u003eData file (PDF)\u003c\/a\u003e\u003c\/li\u003e\u003c\/ul\u003e","brand":"Cytiva","offers":[{"title":"500 mL (SH30084.03IH25-40)","offer_id":45982129160271,"sku":"SH30084.03IH25-40","price":3206.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30084.03IR30-45)","offer_id":45982129193039,"sku":"SH30084.03IR30-45","price":2915.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30084.03IR30-40)","offer_id":45982129225807,"sku":"SH30084.03IR30-40","price":2915.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30084.03HI)","offer_id":45982129258575,"sku":"SH30084.03HI","price":2915.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30084.03IR25-40)","offer_id":45982129291343,"sku":"SH30084.03IR25-40","price":2915.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30084.03)","offer_id":45982129324111,"sku":"SH30084.03","price":2787.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/digi-23384-original-png_72dd9205-83fd-4091-b15b-8baaec8061da.png?v=1785958609"},{"product_id":"hyclone-defined-fetal-bovine-serum-fbs-australian-origin-sh31195-03ir30-45","title":"HyClone™ Defined Fetal Bovine Serum (FBS), Australian Origin","description":"\u003cp\u003eOur highest quality FBS, HyClone™ AU-origin defined FBS is proprietary serial 40 nm-filtered, virus-tested to 9 CFR standard, and supplied with an extensive biochemical profile.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eWell-defined: assay results for over 50 components, with additional testing available\u003c\/li\u003e\n\u003cli\u003eAU origin: sourced in Australia and processed in New Zealand with complete traceability to origin\u003c\/li\u003e\n\u003cli\u003eUltra-low endotoxin: ≤ 5 EU\/mL endotoxin for reduced research and production risk\u003c\/li\u003e\n\u003cli\u003eSterile-filtered: proprietary serial 40 nm filter process\u003c\/li\u003e\n\u003cli\u003ePost-filtration treatments: γ-irradiated and heat-inactivated FBS options are available\u003c\/li\u003e\n\u003cli\u003eVirus-tested: broad virus panel testing in accordance with 9 CFR 113.53\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003ePurchase orders with specific lot requests, quoted reserves and\/or call off orders should be submitted through \u003ca href=\"\/support\/contact-us\"\u003eCustomer Service\u003c\/a\u003e.\u003c\/em\u003e\u003c\/p\u003e\n\n\u003cp\u003eFetal bovine serum (FBS) is a nutrient-rich cell culture supplement that is high in growth factors and low in antibodies, compared to non-fetal sera.\u003c\/p\u003e\n\n\u003cp\u003eDefined FBS for cell culture confidence and consistency\u003c\/p\u003e\n\n\u003cp\u003eHyClone™ Defined FBS is widely used by cell culturists who have a concern for viral contaminants and require an extensive biochemical profile. The final serum is assayed for over 50 components, including proteins, hormones, growth factors, metabolites, and nutrients important for cell culture. Assay results are included in the certificate of analysis and the biochemical assay list. Additional testing, including EMEA conformance testing, is also available.\u003c\/p\u003e\n\n\u003cp\u003eExceptionally low endotoxin levels\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin contamination is a significant concern when producing cell culture-derived products for use in humans or animals. The presence of endotoxin in cell cultures can also have adverse and unpredictable effects on cell growth, function and phenotype that can compromise research results. Our patented closed-system blood collection method and rigorous quality control testing ensure that HyClone™ Defined FBS contains ≤ 5 EU\/mL endotoxin and ≤ 15 mg\/dL hemoglobin. Low hemoglobin levels in the final product are an indication that extensive cell lysis has not occurred, confirming that the fetal blood has been handled appropriately during collection and transport.\u003c\/p\u003e\n\n\u003cp\u003eVirus-tested and quality-assured for reduced contamination risk\u003c\/p\u003e\n\n\u003cp\u003eHyClone™ Defined FBS is filtered through proprietary serial 40 nm (0.04 μm) pore size-rated filters, which are the most retentive filters used in commercial FBS production. This type of filtration is practical in reducing risk while maintaining high performance in cell growth.\u003c\/p\u003e\n\n\u003cp\u003eStudies demonstrate that this filtration regimen has no adverse effect on cell growth. Before dispensing, each lot of serum is pooled using true pool technology to ensure uniformity and consistency between bottles.\u003c\/p\u003e\n\n\u003cp\u003eThe final serum is virus-tested according to 9 CFR 113.53 to demonstrate that there are no detectable levels of specified viruses, pathogenic agents, and hemadsorbing agents. Robust sterility testing further confirms that the final product contains no detectable growth of bacteria or fungi (current USP) and no detectable mycoplasma.\u003c\/p\u003e\n\n\u003cp\u003ePost-filtration treatments for added process security\u003c\/p\u003e\n\n\u003cp\u003eGamma-irradiated and heat-inactivated FBS options are available to further reduce the risk of adventitious agents, particularly when manufacturing products for use in humans or animals. The irradiation process is validated to deliver multiple validated dose ranges starting at 25 kGy.\u003c\/p\u003e\n\n\u003cp\u003eRegulatory and supply chain security\u003c\/p\u003e\n\n\u003cp\u003eFor decades, Cytiva's HyClone™ premium bovine serum products have exceeded industry standards for quality, purity, and regulatory compliance. HyClone™ serum processes are traceability-certified by the International Serum Industry Association (ISIA). In addition, Cytiva has chosen to be an early adopter of scientific traceability by Oritain™ to prove the country of origin of their premium bovine serum products from the United States, Australia, and New Zealand. Premium bovine serum samples from different regions have been analyzed and Oritain has created a database of the unique ‘Origin Fingerprint’ that is exclusive to each country of origin. \u003ca href=\"https:\/\/oritain.com\/verified\/verified-partners\/cytiva\/\" target=\"_blank\"\u003eLearn more.\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eTemperature excursions happen, both in transport and on the bench. \u003ca href=\"\/solutions\/bioprocessing\/knowledge-center\/fetal-bovine-serum-storage-temperature\"\u003eStorage condition effects on fetal bovine serum for cell culture whitepaper\u003c\/a\u003e shows how HyClone™ serum maintain viable cell density and cell growth and stay within specification under various temperatures and timeframes.\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-17854-pdf\"\u003eData file (PDF)\u003c\/a\u003e\u003c\/li\u003e\u003c\/ul\u003e","brand":"Cytiva","offers":[{"title":"50 mL (SH31195.01HI)","offer_id":45982129651791,"sku":"SH31195.01HI","price":570.0,"currency_code":"ILS","in_stock":true},{"title":"50 mL (SH31195.01)","offer_id":45982129684559,"sku":"SH31195.01","price":429.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH31195.03IR30-45)","offer_id":45982129717327,"sku":"SH31195.03IR30-45","price":3129.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH31195.03HI)","offer_id":45982129750095,"sku":"SH31195.03HI","price":3129.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH31195.03)","offer_id":45982129782863,"sku":"SH31195.03","price":3069.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/N9bNOFxSQQ-9tq2lA7RjFw-original-png_7f8546fa-c7b3-420f-8551-7e68a7b5fb2a.png?v=1785958612"},{"product_id":"hyclone-dialyzed-fetal-bovine-serum-fbs-u-s-origin-sh30079-03ih25-40","title":"HyClone™ dialyzed Fetal Bovine Serum (FBS), U.S. origin","description":"\u003cp\u003eFor applications that need serum without low molecular weight components.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSourced in the USA with complete traceability back to original source\u003c\/li\u003e\n\u003cli\u003eLow in antibodies and high in growth factors\u003c\/li\u003e\n\u003cli\u003eProduced using true pool technology for uniformity and consistency from bottle to bottle\u003c\/li\u003e\n\u003cli\u003eFiltered through three sequential 100nm (0.1um) pore size-rated filters\u003c\/li\u003e\n\u003cli\u003eVirus panel testing according to 9 CFR 113.53\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003ePurchase orders with specific lot requests, quoted reserves and\/or call off orders should be submitted through \u003ca href=\"\/support\/contact-us\"\u003eCustomer Service.\u003c\/a\u003e\u003c\/em\u003e\u003c\/p\u003e\n\n\u003cp\u003eHyClone Dialyzed Fetal Bovine Serum is used in applications requiring serum depleted from low-molecular weight components of less than Mr 10 000. The serum is subjected to dialysis through a diafiltration process that reduces concentrations of small molecules such as nucleotides and amino acids that are necessary for alternative biochemical survival pathways. The process reduces hypoxanthine and thymidine concentrations below detectable levels. While producing the same results, a major difference between diafiltration and traditional dialysis is that the driving force for diafiltration is hydrostatic pressure, rather than the concentration gradient for traditional dialysis. Monitoring glucose concentrations carefully controls the diafiltration process. The glucose concentration, which is representative of the extent of dialysis, is reported for each lot of serum.\u003c\/p\u003e\u003cp\u003eDialyzed FBS is assayed for gamma globulin, alkaline phosphatase, lactate dehydrogenase, glutamic pyruvic transaminase, glutamic oxaloacetic transaminase, pH, total protein, albumin, blood urea nitrogen, creatinine, total bilirubin, sodium, potassium, calcium, chloride, inorganic phosphorus, osmolality, iron, total iron binding capacity (TIBC), percent iron saturation, glucose, and IgG. Included assays are subject to change without notice.\u003c\/p\u003e\u003cp\u003eAdditional treatments available including heat-inactivation and irradiation. Additional testing, including EMEA-conforming testing, is also available.\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-17828-pdf\"\u003eData file (PDF)\u003c\/a\u003e\u003c\/li\u003e\u003c\/ul\u003e","brand":"Cytiva","offers":[{"title":"50 mL (SH30079.01HI)","offer_id":45982129881167,"sku":"SH30079.01HI","price":476.0,"currency_code":"ILS","in_stock":true},{"title":"50 mL (SH30079.01)","offer_id":45982129913935,"sku":"SH30079.01","price":385.0,"currency_code":"ILS","in_stock":true},{"title":"100 mL (SH30079.02HI)","offer_id":45982129946703,"sku":"SH30079.02HI","price":750.0,"currency_code":"ILS","in_stock":true},{"title":"100 mL (SH30079.02)","offer_id":45982129979471,"sku":"SH30079.02","price":660.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30079.03IH25-40)","offer_id":45982130012239,"sku":"SH30079.03IH25-40","price":2965.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30079.03IR25-40)","offer_id":45982130045007,"sku":"SH30079.03IR25-40","price":2858.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30079.03HI)","offer_id":45982130077775,"sku":"SH30079.03HI","price":2858.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30079.03)","offer_id":45982130110543,"sku":"SH30079.03","price":2754.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/digi-26812-original-png_ddac5794-6a17-4445-95ff-4a4148186458.png?v=1785958601"},{"product_id":"hyclone-characterized-fetal-bovine-serum-fbs-new-zealand-origin-sh30406-02ih25-40","title":"HyClone™ Characterized Fetal Bovine Serum (FBS), New Zealand Origin","description":"\u003cp\u003eEnhance growth of cells with New Zealand sourced HyClone Characterized Fetal Bovine Serum.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSourced in New Zealand with complete traceability back to the original source.\u003c\/li\u003e\n\u003cli\u003eLow in antibodies and high in growth factors\u003c\/li\u003e\n\u003cli\u003eProduced using true pool technology for uniformity and consistency from bottle to bottle\u003c\/li\u003e\n\u003cli\u003eFiltered through three sequential 100 nm (0.1 µm) pore size-rated filters\u003c\/li\u003e\n\u003cli\u003eVirus panel testing according to 9 CFR 113.53\u003c\/li\u003e\n\u003cli\u003eEndotoxin-tested: certificate of analysis confirms ≤ 10 EU\/mL endotoxin\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003ePurchase orders with specific lot requests, quoted reserves and\/or call off orders should be submitted through \u003ca href=\"\/support\/contact-us\"\u003eCustomer Service.\u003c\/a\u003e\u003c\/em\u003e\u003c\/p\u003e\n\n\u003cp\u003eHyClone Characterized Fetal Bovine Serum (FBS), New Zealand Origin is carefully collected, processed, and filtered in our own New Zealand facility. The great expanse of the Pacific ocean has protected New Zealand’s islands from many outside influences, both geographically and biologically. One of the benefits of this isolation is that New Zealand has the fewest reported bovine diseases in the world, making Characterized FBS, New Zealand Origin an excellent source of bovine serum as it offers greater security.\u003c\/p\u003e\n\n\u003cp\u003eCharacterized FBS is assayed for gamma globulin, alkaline phosphatase, lactate dehydrogenase, glutamic pyruvic transaminase, glutamic oxaloacetic transaminase, pH, total protein, albumin, blood urea nitrogen, creatinine, total bilirubin, sodium, potassium, calcium, chloride, inorganic phosphorus, osmolality, iron, total iron binding capacity (TIBC), percent iron saturation, glucose, and IgG. Included assays are subject to change without notice.\u003c\/p\u003e\n\n\u003cp\u003eAdditional treatments available including heat-inactivation and irradiation. Additional testing, including EMEA-conforming testing, is also available.\u003c\/p\u003e\n\n\u003cp\u003eFor decades, Cytiva's HyClone™ premium bovine serum products have exceeded industry standards for quality, purity, and regulatory compliance. HyClone™ serum processes are traceability certified by the International Serum Industry Association (ISIA) and, in addition, Cytiva has chosen to be an early adopter of scientific traceability by Oritain to prove the country of origin of their premium bovine serum products from the United States, Australia and New Zealand. Premium bovine serum samples from different regions have been analyzed and Oritain has created a database of the unique ‘Origin Fingerprint’ that is exclusive to each country of origin. Learn more \u003ca href=\"https:\/\/oritain.com\/partners\/cytiva\" target=\"_blank\"\u003ehttps:\/\/oritain.com\/partners\/cytiva\u003c\/a\u003e\u003c\/p\u003e\n\n\u003cp\u003eHave Confidence in Security of Supply with Secondary Sourcing\u003c\/p\u003e\n\n\u003cp\u003eFetal Bovine Serum from a single origin may be limited, so it’s important to qualify FBS products from other countries to increase your security of supply. HyClone Characterized FBS from United States (US), New Zealand (NZ) and Australia (AUS) have been evaluated and tested to show equivalent performance. \u003ca href=\"\/solutions\/bioprocessing\/knowledge-center\/fbs-origin-equivalence-study\"\u003eRead our full study\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003eTemperature excursions happen, both in transport and on the bench. \u003ca href=\"\/solutions\/bioprocessing\/knowledge-center\/fetal-bovine-serum-storage-temperature\"\u003eStorage condition effects on fetal bovine serum for cell culture whitepaper\u003c\/a\u003e shows how HyClone™ serum maintain viable cell density and cell growth and stay within specification under various temperatures and timeframes.\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-17664-pdf\"\u003eData file (PDF)\u003c\/a\u003e\u003c\/li\u003e\u003c\/ul\u003e","brand":"Cytiva","offers":[{"title":"500 mL (SH30406.02IH25-40)","offer_id":45982130143311,"sku":"SH30406.02IH25-40","price":3082.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30406.02HI)","offer_id":45982130176079,"sku":"SH30406.02HI","price":2998.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30406.02IR30-45)","offer_id":45982130208847,"sku":"SH30406.02IR30-45","price":2998.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30406.02IR25-40)","offer_id":45982130241615,"sku":"SH30406.02IR25-40","price":2998.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30406.02)","offer_id":45982130274383,"sku":"SH30406.02","price":2911.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30406.02IR30-40)","offer_id":45982130307151,"sku":"SH30406.02IR30-40","price":2998.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/digi-23382-original-png_5252c55c-984f-4493-80cc-25710e869f56.png?v=1785958616"},{"product_id":"hyclone-characterized-tetracycline-screened-fetal-bovine-serum-fbs-u-s-origin-sh30071-03tih25-40","title":"HyClone™ Characterized Tetracycline Screened Fetal Bovine Serum (FBS), U.S. origin","description":"\u003cp\u003eEnhance cell culture growth with U.S. sourced Cytiva HyClone™ Characterized Fetal Bovine Serum (FBS), screened for undetectable tetracycline levels, designed for researchers using tetracycline-regulated gene expression in cultured cells, and filtered through sequential 100 nm pore-size filters.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSuitable for expression studies in Tet-on\/Tet-off systems\u003c\/li\u003e\n\u003cli\u003eSourced in the USA with complete traceability back to original source\u003c\/li\u003e\n\u003cli\u003eLow in antibodies and high in growth factors\u003c\/li\u003e\n\u003cli\u003eVirus panel testing according to 9 CFR 113.53\u003c\/li\u003e\n\u003cli\u003e100 nm filtration\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003ePurchase orders with specific lot requests, quoted reserves and\/or call off orders should be submitted through \u003ca href=\"\/support\/contact-us\"\u003eCustomer Service.\u003c\/a\u003e\u003c\/em\u003e\u003c\/p\u003e\n\n\u003cp\u003eHyClone™ Characterized Tetracycline Screened Fetal Bovine Serum (FBS) is designed for researchers using tetracycline-regulated gene expression systems in cultured cells. These systems rely on the presence or absence of tetracycline in the growth medium to either turn off or turn on gene expression. The presence of tetracycline in the serum might interfere with such systems. To eliminate the possibility of interference, the tetracycline content of several Characterized FBS lots is determined by ELISA. The lots with undetectable tetracycline levels are selected as Tetracycline Screened FBS.\u003c\/p\u003e\n\n\u003cp\u003eHyClone™ Characterized Fetal Bovine Serum (FBS) is produced using true pool processing, which minimizes bottle-to-bottle variability. This FBS product is filtered through three sequential 100 nm (0.1 µm) pore size-rated filters. Each lot of FBS is subjected to virus panel testing according to 9 CFR 113.53. HyClone™ Characterized FBS is assayed for many components, including gamma globulin, glucose, and IgG.\u003c\/p\u003e\n\n\u003cp\u003eAdditional treatments available including heat-inactivation and irradiation. Additional testing, including EMA-conforming testing, is also available.\u003c\/p\u003e\n\u003cp\u003eTemperature excursions happen, both in transport and on the bench. \u003ca href=\"\/solutions\/bioprocessing\/knowledge-center\/fetal-bovine-serum-storage-temperature\"\u003eStorage condition effects on fetal bovine serum for cell culture whitepaper\u003c\/a\u003e shows how HyClone™ serum maintain viable cell density and cell growth and stay within specification under various temperatures and timeframes.\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-17982-pdf\"\u003eData file (PDF)\u003c\/a\u003e\u003c\/li\u003e\u003c\/ul\u003e","brand":"Cytiva","offers":[{"title":"500 mL (SH30071.03TIH25-40)","offer_id":45982130405455,"sku":"SH30071.03TIH25-40","price":2965.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30071.03TH)","offer_id":45982130438223,"sku":"SH30071.03TH","price":2754.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30071.03T)","offer_id":45982130470991,"sku":"SH30071.03T","price":2650.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/digi-26613-original-png_0d275a5b-ec7e-4623-bc42-6ddf1f1ac9a9.png?v=1785958620"},{"product_id":"hyclone-charcoal-dextran-treated-fetal-bovine-serum-u-s-origin-sh30068-03ir25-40","title":"HyClone™ Charcoal\/Dextran treated Fetal Bovine Serum, U.S. Origin","description":"\u003cp\u003eContains reduced levels of many hormones and growth factors.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSourced in the USA with complete traceability back to original source\u003c\/li\u003e\n\u003cli\u003eProduced using true pool technology for uniformity and consistency from bottle to bottle\u003c\/li\u003e\n\u003cli\u003eFiltered through three sequential 100nm (0.1um) pore size-rated filters\u003c\/li\u003e\n\u003cli\u003eVirus panel testing according to 9 CFR 113.53\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003ePurchase orders with specific lot requests, quoted reserves and\/or call off orders should be submitted through \u003ca href=\"\/support\/contact-us\"\u003eCustomer Service.\u003c\/a\u003e\u003c\/em\u003e\u003c\/p\u003e\n\n\u003cp\u003eHyClone charcoal\/dextran treated Fetal Bovine Serum is available for users requiring reduced levels of various hormones. High-quality FBS is processed using a proprietary charcoal\/dextran treatment that has been shown to reduce the levels of many hormones and growth factors. Charcoal\/dextran treatment has been shown to be effective in reducing steroid levels for use of the serum in receptor studies or estrogen-related investigations. Other studies indicate that charcoal\/dextran treatments may be used to minimize lot-to-lot serum variability.\u003c\/p\u003e\n\n\u003cp\u003eCharcoal\/Dextran Treated FBS is assayed for gamma globulin, alkaline phosphatase, lactate dehydrogenase, glutamic pyruvic transaminase, glutamic oxaloacetic transaminase, pH, total protein, albumin, blood urea nitrogen, creatinine, total bilirubin, sodium, potassium, calcium, chloride, inorganic phosphorus, osmolality, iron, total iron binding capacity (TIBC), percent iron saturation, glucose, and IgG. Included assays are subject to change without notice.\u003c\/p\u003e\n\n\u003cp\u003eAdditional treatments available including heat-inactivation and irradiation. Additional testing, including EMEA-conforming testing, is also available.\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-17977-pdf\"\u003eData file (PDF)\u003c\/a\u003e\u003c\/li\u003e\u003c\/ul\u003e","brand":"Cytiva","offers":[{"title":"50 mL (SH30068.01HI)","offer_id":45982130503759,"sku":"SH30068.01HI","price":486.0,"currency_code":"ILS","in_stock":true},{"title":"50 mL (SH30068.01)","offer_id":45982130536527,"sku":"SH30068.01","price":395.0,"currency_code":"ILS","in_stock":true},{"title":"100 mL (SH30068.02HI)","offer_id":45982130569295,"sku":"SH30068.02HI","price":760.0,"currency_code":"ILS","in_stock":true},{"title":"100 mL (SH30068.02)","offer_id":45982130602063,"sku":"SH30068.02","price":670.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30068.03IR25-40)","offer_id":45982130634831,"sku":"SH30068.03IR25-40","price":2911.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30068.03HI)","offer_id":45982130667599,"sku":"SH30068.03HI","price":2911.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30068.03)","offer_id":45982130700367,"sku":"SH30068.03","price":2804.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/digi-23356-original-png_08b3dce6-1509-4dd5-b60d-e9f69cc9ef14.png?v=1785958621"},{"product_id":"hyclone-characterized-embryonic-stem-cell-screened-fetal-bovine-serum-fbs-u-s-origin-sh30071-03eh","title":"HyClone™ Characterized Embryonic Stem Cell Screened Fetal Bovine Serum (FBS), U.S. origin","description":"\u003cp\u003eEnhance growth of cells with U.S. sourced Cytiva HyClone™ Characterized Embryonic Stem (ES) Cell Screened Fetal Bovine Serum (FBS), filtered through serial 100 nm pore-size rated filters and tested for endotoxin, hemoglobin, and extensive biochemical profile assays.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSupports the growth of undifferentiated murine embryonic stem cells\u003c\/li\u003e\n\u003cli\u003eTested according to a protocol adapted from Gene Targeting, A.L. Joyner, 1995\u003c\/li\u003e\n\u003cli\u003eSourced in the USA with complete traceability back to the original source.\u003c\/li\u003e\n\u003cli\u003eLow in antibodies and high in growth factors\u003c\/li\u003e\n\u003cli\u003eVirus panel testing according to 9 CFR 113.53\u003c\/li\u003e\n\u003cli\u003e100 nm filtration\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003ePurchase orders with specific lot requests, quoted reserves and\/or call off orders should be submitted through \u003ca href=\"\/support\/contact-us\"\u003eCustomer Service.\u003c\/a\u003e\u003c\/em\u003e\u003c\/p\u003e\n\n\u003cp\u003eHyClone™ Characterized ES (Murine) Screened FBS minimizes the need for prescreening serum, saving both time and money, while providing the assurance that the serum used has been screened by experienced ES cell culturists. The screening includes plating efficiency, colony morphology, and toxicity tests.\u003c\/p\u003e\n\n\u003cp\u003eHyClone™ Characterized Fetal Bovine Serum (FBS) is produced using true pool processing, which minimizes bottle-to-bottle variability. This FBS product is filtered through three sequential 100 nm (0.1 µm) pore size-rated filters. Each lot of FBS is subjected to virus panel testing according to 9 CFR 113.53. HyClone™ Characterized FBS is assayed for many components, including gamma globulin, glucose, and IgG.\u003c\/p\u003e\n\n\u003cp\u003eAdditional treatments available including heat-inactivation and irradiation. Additional testing, including EMA-conforming testing, is also available.\u003c\/p\u003e\n\u003cp\u003eTemperature excursions happen, both in transport and on the bench. \u003ca href=\"\/solutions\/bioprocessing\/knowledge-center\/fetal-bovine-serum-storage-temperature\"\u003eStorage condition effects on fetal bovine serum for cell culture whitepaper\u003c\/a\u003e shows how HyClone™ serum maintain viable cell density and cell growth and stay within specification under various temperatures and timeframes.\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-18128-pdf\"\u003eData file (PDF)\u003c\/a\u003e\u003c\/li\u003e\u003c\/ul\u003e","brand":"Cytiva","offers":[{"title":"100 mL (SH30071.02EH)","offer_id":45982130798671,"sku":"SH30071.02EH","price":838.0,"currency_code":"ILS","in_stock":true},{"title":"100 mL (SH30071.02E)","offer_id":45982130831439,"sku":"SH30071.02E","price":750.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30071.03EH)","offer_id":45982130864207,"sku":"SH30071.03EH","price":2754.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30071.03E)","offer_id":45982130896975,"sku":"SH30071.03E","price":2650.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/digi-26827-original-png_d3a5700f-f8b2-4a34-ae6f-b8786003f152.png?v=1785958623"},{"product_id":"hyclone-characterized-fetal-bovine-serum-fbs-u-s-origin-sh30071-03ih30-45","title":"HyClone™ Characterized Fetal Bovine Serum (FBS), U.S. Origin","description":"\u003cp\u003eEnhance growth of cells with U.S. sourced HyClone Characterized Fetal Bovine Serum (FBS).\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eHyClone characterized fetal bovine serum (FBS) is sourced in the USA. Complete traceability is provided back to the original source, as certified by the International Serum Industry Association (ISIA).\u003c\/li\u003e\n\u003cli\u003eAdditional traceability testing of premium HyClone fetal bovine serum is performed by our collaborator, Oritain.\u003c\/li\u003e\n\u003cli\u003eHyClone FBS serum is low in antibodies and high in growth factors to support robust growth and division of cells, including embryonic stem cells.\u003c\/li\u003e\n\u003cli\u003eEndotoxin-tested: certificate of analysis confirms ≤ 10 EU\/mL endotoxin\u003c\/li\u003e\n\u003cli\u003eTriple-filtered: Triple 100 nm pore size-rated filtering for reliable microbial depletion\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003ePurchase orders with specific lot requests, quoted reserves, and\/or call-off orders should be submitted through \u003ca href=\"\/support\/contact-us\"\u003eCustomer Service.\u003c\/a\u003e\u003c\/em\u003e\u003c\/p\u003e\n\n\u003cp\u003eHyClone characterized fetal bovine serum (FBS) is produced using true pool technology, which minimizes bottle-to-bottle variability. This FBS product is filtered through three sequential 100 nm (0.1 µm) pore size-rated filters. Each lot of FBS is subjected to virus panel testing according to 9 CFR 113.53. HyClone characterized FBS is assayed for many components, including gamma globulin, glucose, and IgG.\u003c\/p\u003e\n\n\u003cp\u003eAdditional treatments are available: HyClone FBS heat inactivated (HI) and HyClone FBS irradiated (IR). Additional testing, including EMEA-conforming testing, is also available.\u003c\/p\u003e\n\n\u003cp\u003eFetal bovine serum used in cell culture\u003c\/p\u003e\n\n\u003cp\u003eFetal bovine serum (FBS) is frequently added to cell culture media to promote cell growth and division. Because of its high content of growth factors and other nutrients that meet the metabolic needs of eukaryotic cells, FBS serum is frequently used to grow mammalian cells including embryonic stem cells.\u003c\/p\u003e\n\n\u003cp\u003eHyClone FBS is certified for traceability\u003c\/p\u003e\n\n\u003cp\u003eThe manufacturing processes used to create HyClone serum are traceability certified by the International Serum Industry Association (ISIA). To further support product traceability, we were an early adopter of \u003ca href=\"https:\/\/oritain.com\/partners\/cytiva\" target=\"_blank\"\u003eScientific Traceability by Oritain\u003c\/a\u003e to prove the country of origin of premium bovine sera products from the United States, Australia, and New Zealand. Premium bovine serum samples from different regions have been analyzed, and Oritain has created a database of the unique 'Origin Fingerprint' exclusive to each country of origin.\u003c\/p\u003e\n\n\u003cp\u003eHave Confidence in Security of Supply with Secondary Sourcing\u003c\/p\u003e\n\n\u003cp\u003eFetal Bovine Serum from a single origin may be limited, so it’s important to qualify FBS products from other countries to increase your security of supply. HyClone Characterized FBS from United States (US), New Zealand (NZ) and Australia (AUS) have been evaluated and tested to show equivalent performance. \u003ca href=\"\/solutions\/bioprocessing\/knowledge-center\/fbs-origin-equivalence-study\"\u003eRead our full study\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003eTemperature excursions happen, both in transport and on the bench. \u003ca href=\"\/solutions\/bioprocessing\/knowledge-center\/fetal-bovine-serum-storage-temperature\"\u003eStorage condition effects on fetal bovine serum for cell culture whitepaper\u003c\/a\u003e shows how HyClone™ serum maintain viable cell density and cell growth and stay within specification under various temperatures and timeframes.\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-17551-pdf\"\u003eData file (PDF)\u003c\/a\u003e\u003c\/li\u003e\u003c\/ul\u003e","brand":"Cytiva","offers":[{"title":"50 mL (SH30071.01HI)","offer_id":45982130929743,"sku":"SH30071.01HI","price":449.0,"currency_code":"ILS","in_stock":true},{"title":"50 mL (SH30071.01)","offer_id":45982130962511,"sku":"SH30071.01","price":358.0,"currency_code":"ILS","in_stock":true},{"title":"100 mL (SH30071.02HI)","offer_id":45982130995279,"sku":"SH30071.02HI","price":693.0,"currency_code":"ILS","in_stock":true},{"title":"100 mL (SH30071.02)","offer_id":45982131028047,"sku":"SH30071.02","price":603.0,"currency_code":"ILS","in_stock":true},{"title":"100 mL (SH30071.02IR25-40)","offer_id":45982131060815,"sku":"SH30071.02IR25-40","price":821.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30071.03IH30-45)","offer_id":45982131093583,"sku":"SH30071.03IH30-45","price":2717.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30071.03IH25-40)","offer_id":45982131126351,"sku":"SH30071.03IH25-40","price":2717.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30071.03HI)","offer_id":45982131159119,"sku":"SH30071.03HI","price":2613.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30071.03IR25-40)","offer_id":45982131191887,"sku":"SH30071.03IR25-40","price":2613.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30071.03IR30-45)","offer_id":45982131224655,"sku":"SH30071.03IR30-45","price":2613.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30071.03)","offer_id":45982131257423,"sku":"SH30071.03","price":2506.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/digi-23380-original-png.png?v=1782740579"},{"product_id":"hyclone-characterized-insect-cell-screened-fetal-bovine-serum-fbs-u-s-origin-sh30071-03i","title":"HyClone™ Characterized Insect Cell Screened Fetal Bovine Serum (FBS), U.S. origin","description":"\u003cp\u003eEnhance cell culture growth with U.S. sourced Cytiva HyClone™ Characterized Insect Cell Screened Fetal Bovine Serum (FBS), filtered through serial 100 nm pore-size rated filters and identified through lots that offer exceptional performance with baculovirus expression vector systems (BEVS).\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eOptimizes growth performance of insect cells\u003c\/li\u003e\n\u003cli\u003eSourced in the USA with complete traceability back to original source\u003c\/li\u003e\n\u003cli\u003eLow in antibodies and high in growth factors\u003c\/li\u003e\n\u003cli\u003eVirus panel testing according to 9 CFR 113.53\u003c\/li\u003e\n\u003cli\u003e100 nm filtration\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003ePurchase orders with specific lot requests, quoted reserves and\/or call off orders should be submitted through \u003ca href=\"\/support\/contact-us\"\u003eCustomer Service.\u003c\/a\u003e\u003c\/em\u003e\u003c\/p\u003e\n\n\u003cp\u003eWith use of baculovirus expression vector systems (BEVS), more researchers are culturing insect cells. The serum is screened to identify lots that offer excellent performance with BEVS. This screening involves comparing cell yield and viability using insect cells grown in various test lots for four passages. These test lots are compared with a control lot that has demonstrated the ability to support robust growth of insect cells.\u003c\/p\u003e\n\n\u003cp\u003eHyClone™ Characterized Fetal Bovine Serum (FBS) is produced using true pool processing, which minimizes bottle-to-bottle variability. This FBS product is filtered through three sequential 100 nm (0.1 µm) pore size-rated filters. Each lot of FBS is subjected to virus panel testing according to 9 CFR 113.53. HyClone™ Characterized FBS is assayed for many components, including gamma globulin, glucose, and IgG.\u003c\/p\u003e\n\n\u003cp\u003eAdditional treatments available including heat-inactivation and irradiation. Additional testing, including EMA-conforming testing, is also available.\u003c\/p\u003e\n\u003cp\u003eTemperature excursions happen, both in transport and on the bench. \u003ca href=\"\/solutions\/bioprocessing\/knowledge-center\/fetal-bovine-serum-storage-temperature\"\u003eStorage condition effects on fetal bovine serum for cell culture whitepaper\u003c\/a\u003e shows how HyClone™ serum maintain viable cell density and cell growth and stay within specification under various temperatures and timeframes.\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-17981-pdf\"\u003eData file (PDF)\u003c\/a\u003e\u003c\/li\u003e\u003c\/ul\u003e","brand":"Cytiva","offers":[{"title":"500 mL","offer_id":45982131388495,"sku":"SH30071.03I","price":2650.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/digi-41412-original-png_9ae9f561-b986-495c-8fcd-0c37ae46de2c.png?v=1785958629"},{"product_id":"hyclone-characterized-human-mesenchymal-stem-cell-screened-fetal-bovine-serum-fbs-u-s-origin-sh30071","title":"HyClone™ Characterized Human Mesenchymal Stem Cell Screened Fetal Bovine Serum (FBS), U.S. origin","description":"\u003cp\u003eEnhance human mesenchymal stem cell growth.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eDesigned for human mesenchymal stem cells\u003c\/li\u003e\n\u003cli\u003eSourced in the USA with complete traceability back to original source\u003c\/li\u003e\n\u003cli\u003eLow in antibodies and high in growth factors\u003c\/li\u003e\n\u003cli\u003eVirus panel testing according to 9 CFR 113.53\u003c\/li\u003e\n\u003cli\u003e100 nm filtration\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003ePurchase orders with specific lot requests, quoted reserves and\/or call off orders should be submitted through \u003ca href=\"\/support\/contact-us\"\u003eCustomer Service.\u003c\/a\u003e\u003c\/em\u003e\u003c\/p\u003e\n\n\u003cp\u003eEach lot is screened by growing human mesenchymal stem cells (hMSC) over a minimum of three subculture generations with 10 percent serum. Human MSC are then observed for evidence of nutritional deficiency, cytotoxicity or morphological aberrations. The serum is tested in parallel with a control lot which has been demonstrated to support the growth of hMSC.\u003c\/p\u003e\n\n\u003cp\u003eHyClone™ Characterized Fetal Bovine Serum (FBS) is produced using true pool processing, which minimizes bottle-to-bottle variability. This FBS product is filtered through three sequential 100 nm (0.1 µm) pore size-rated filters. Each lot of FBS is subjected to virus panel testing according to 9 CFR 113.53. HyClone™ Characterized FBS is assayed for many components, including gamma globulin, glucose, and IgG.\u003c\/p\u003e\n\n\u003cp\u003eAdditional treatments available including heat-inactivation and irradiation. Additional testing, including EMA-conforming testing, is also available.\u003c\/p\u003e\n\n\u003cp\u003eTemperature excursions happen, both in transport and on the bench. \u003ca href=\"\/solutions\/bioprocessing\/knowledge-center\/fetal-bovine-serum-storage-temperature\"\u003eStorage condition effects on fetal bovine serum for cell culture whitepaper\u003c\/a\u003e shows how HyClone™ serum maintain viable cell density and cell growth and stay within specification under various temperatures and timeframes.\u003c\/p\u003e","brand":"Cytiva","offers":[{"title":"500 mL","offer_id":45982131355727,"sku":"SH30071.03M","price":2650.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/69c2a45ee6724ce6b5869640310fc044_c0068a0c-cd59-4882-b332-109d471ad662.png?v=1785956229"},{"product_id":"hyclone-standard-fetal-bovine-serum-fbs-u-s-origin-sh30088-03ih25-40","title":"HyClone™ Standard Fetal Bovine Serum (FBS), U.S. Origin","description":"\u003cp\u003eEnhance cell culture growth with U.S. sourced quality cell culture-grade HyClone Standard Fetal Bovine Serum.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSourced in the USA with complete traceability back to original source\u003c\/li\u003e\n\u003cli\u003eLow in antibodies and high in growth factors\u003c\/li\u003e\n\u003cli\u003eProduced using true pool technology for uniformity and consistency from bottle to bottle\u003c\/li\u003e\n\u003cli\u003eFiltered through three sequential 100 nm (0.1 µm) pore size-rated filters\u003c\/li\u003e\n\u003cli\u003eVirus panel testing according to 9 CFR 113.53\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003ePurchase orders with specific lot requests, quoted reserves and\/or call off orders should be submitted through \u003ca href=\"\/support\/contact-us\"\u003eCustomer Service.\u003c\/a\u003e\u003c\/em\u003e\u003c\/p\u003e\n\n\u003cp\u003eHyClone Standard Fetal Bovine Serum (FBS), U.S. origin is an economical alternative to characterized and defined FBS. Standard FBS is ideal for research applications.\u003c\/p\u003e\n\n\u003cp\u003eStandard FBS is assayed for gamma globulin, alkaline phosphatase, lactate dehydrogenase, glutamic pyruvic transaminase, glutamic oxaloacetic transaminase, pH, total protein, albumin, blood urea nitrogen, creatinine, total bilirubin, sodium, potassium, calcium, chloride, inorganic phosphorus, osmolality, iron, total iron binding capacity (TIBC) and IgG. Included assays are subject to change without notice.\u003c\/p\u003e\n\n\u003cp\u003eAdditional treatments available including heat-inactivation and irradiation. Additional testing, including EMEA-conforming testing, is also available.\u003c\/p\u003e\n\u003cp\u003eTemperature excursions happen, both in transport and on the bench. \u003ca href=\"\/solutions\/bioprocessing\/knowledge-center\/fetal-bovine-serum-storage-temperature\"\u003eStorage condition effects on fetal bovine serum for cell culture whitepaper\u003c\/a\u003e shows how HyClone™ serum maintain viable cell density and cell growth and stay within specification under various temperatures and timeframes.\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-17914-pdf\"\u003eData file (PDF)\u003c\/a\u003e\u003c\/li\u003e\u003c\/ul\u003e","brand":"Cytiva","offers":[{"title":"100 mL (SH30088.02HI)","offer_id":45982131519567,"sku":"SH30088.02HI","price":590.0,"currency_code":"ILS","in_stock":true},{"title":"100 mL (SH30088.02)","offer_id":45982131552335,"sku":"SH30088.02","price":570.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30088.03IH25-40)","offer_id":45982131585103,"sku":"SH30088.03IH25-40","price":2245.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30088.03IR25-40)","offer_id":45982131617871,"sku":"SH30088.03IR25-40","price":2141.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30088.03HI)","offer_id":45982131650639,"sku":"SH30088.03HI","price":2141.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30088.03)","offer_id":45982131683407,"sku":"SH30088.03","price":2033.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/digi-23355-original-png_9cc258bf-ae8a-4c98-ba72-902069c1b9c4.png?v=1785958635"},{"product_id":"hyclone-fetalclone-ii-serum-u-s-origin-sh30066-03ih25-40","title":"HyClone™ FetalClone™ II serum, U.S. origin","description":"\u003cp\u003eOptimized for the growth of CHO cells and derivatives.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eOptimized for the growth of CHO cells and derivatives\u003c\/li\u003e\n\u003cli\u003eOffering the same basic formulation as our FetalClone™ I serum, with additional growth factors and supplements\u003c\/li\u003e\n\u003cli\u003eIgG levels comparable with those found in FBS\u003c\/li\u003e\n\u003cli\u003eImproved cell growth performance relative to FBS\u003c\/li\u003e\n\u003cli\u003eHigh lot-to-lot consistency\u003c\/li\u003e\n\u003cli\u003eLow endotoxin and hemoglobin levels\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003ePurchase orders with specific lot requests, quoted reserves and\/or call off orders should be submitted through \u003ca href=\"\/support\/contact-us\"\u003eCustomer Service.\u003c\/a\u003e\u003c\/em\u003e\u003c\/p\u003e\n\n\u003cp\u003eU.S. Sourced HyClone™ FetalClone™ II engineered serum is an economical alternative to Fetal Bovine Serum (FBS), delivering both cost-effectiveness and high performance.\u003c\/p\u003e\n\n\u003cp\u003eSterile filtered using three sequential 100 nm (0.1 µm) pore-size rated filters. Each lot undergoes extensive quality performance and analytical testing\u003c\/p\u003e\n\n\u003cp\u003eAdditional treatments available including heat-inactivation and irradiation. Additional testing, including EMEA-conforming testing, is also available.\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-17798-pdf\"\u003eData file (PDF)\u003c\/a\u003e\u003c\/li\u003e\u003c\/ul\u003e","brand":"Cytiva","offers":[{"title":"100 mL (SH30066.02HI)","offer_id":45982131454031,"sku":"SH30066.02HI","price":399.0,"currency_code":"ILS","in_stock":true},{"title":"100 mL (SH30066.02)","offer_id":45991997079631,"sku":"SH30066.02","price":305.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30066.03IH25-40)","offer_id":45991997112399,"sku":"SH30066.03IH25-40","price":1477.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30066.03IR30-45)","offer_id":45991997145167,"sku":"SH30066.03IR30-45","price":1370.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30066.03IR25-40)","offer_id":45991997177935,"sku":"SH30066.03IR25-40","price":1370.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30066.03HI)","offer_id":45991997210703,"sku":"SH30066.03HI","price":1370.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30066.03)","offer_id":45991997243471,"sku":"SH30066.03","price":1263.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/digi-23350-original-png.png?v=1782740587"},{"product_id":"hyclone-fetalclone-iii-serum-u-s-origin-sh30109-03ir30-45","title":"HyClone™ FetalClone™ III serum, U.S. origin","description":"\u003cp\u003eAn economical alternative to Fetal Bovine Serum (FBS).\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eThe most widely applicable of our FetalClone family of products, designed to include fibroblasts in its applications\u003c\/li\u003e\n\u003cli\u003eOffering the same basic formulation found in FetalClone II, with additional growth factors and supplements\u003c\/li\u003e\n\u003cli\u003eIgG levels comparable with those found in FBS\u003c\/li\u003e\n\u003cli\u003eImproved cell growth performance relative to FBS\u003c\/li\u003e\n\u003cli\u003eHigh lot-to-lot consistency\u003c\/li\u003e\n\u003cli\u003eLow endotoxin and hemoglobin levels\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003ePurchase orders with specific lot requests, quoted reserves and\/or call off orders should be submitted through \u003ca href=\"\/support\/contact-us\"\u003eCustomer Service.\u003c\/a\u003e\u003c\/em\u003e\u003c\/p\u003e\n\n\u003cp\u003eU.S. Sourced HyClone FetalClone III offers the same basic formulation of FetalClone II with additional growth factors and supplements.\u003c\/p\u003e\u003cp\u003eSterile filtered using three sequential  100 nm (0.1 µm) pore-size rated filters. Each lot undergoes extensive quality performance and analytical testing\u003c\/p\u003e\u003cp\u003eAdditional treatments available including heat-inactivation and irradiation. Additional testing, including EMEA-conforming testing, is also available.\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-17799-pdf\"\u003eData file (PDF)\u003c\/a\u003e\u003c\/li\u003e\u003c\/ul\u003e","brand":"Cytiva","offers":[{"title":"100 mL (SH30109.02HI)","offer_id":45982131978319,"sku":"SH30109.02HI","price":399.0,"currency_code":"ILS","in_stock":true},{"title":"100 mL (SH30109.02)","offer_id":45982132011087,"sku":"SH30109.02","price":305.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30109.03IR30-45)","offer_id":45982132043855,"sku":"SH30109.03IR30-45","price":1370.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30109.03HI)","offer_id":45982132076623,"sku":"SH30109.03HI","price":1370.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30109.03IR25-40)","offer_id":45982132109391,"sku":"SH30109.03IR25-40","price":1370.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30109.03)","offer_id":45982132142159,"sku":"SH30109.03","price":1263.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/digi-4039-original-png_73b4c957-c521-446b-a1a1-09ebc06c50f1.png?v=1785958640"},{"product_id":"hyclone-fetalclone-i-serum-u-s-origin-sh30080-03hi","title":"HyClone™ FetalClone™ I serum, U.S. origin","description":"\u003cp\u003eOptimized for the growth of hybridoma cells.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eOptimized for the growth of hybridoma cells\u003c\/li\u003e\n\u003cli\u003eIgG levels comparable with those found in FBS\u003c\/li\u003e\n\u003cli\u003eDemonstrated cell growth performance equivalency to FBS\u003c\/li\u003e\n\u003cli\u003eHigh lot-to-lot consistency\u003c\/li\u003e\n\u003cli\u003eLow endotoxin and hemoglobin levels\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003ePurchase orders with specific lot requests, quoted reserves and\/or call off orders should be submitted through \u003ca href=\"\/support\/contact-us\"\u003eCustomer Service.\u003c\/a\u003e\u003c\/em\u003e\u003c\/p\u003e\n\n\u003cp\u003eSterile filtered using three sequential  100 nm (0.1 µm) pore-size rated filters. Each lot undergoes extensive quality performance and analytical testing\u003c\/p\u003e\u003cp\u003eAdditional treatments available including heat-inactivation and irradiation. Additional testing, including EMEA-conforming testing, is also available.\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-17797-pdf\"\u003eData file (PDF)\u003c\/a\u003e\u003c\/li\u003e\u003c\/ul\u003e","brand":"Cytiva","offers":[{"title":"100 mL (SH30080.02HI)","offer_id":45982131814479,"sku":"SH30080.02HI","price":399.0,"currency_code":"ILS","in_stock":true},{"title":"100 mL (SH30080.02)","offer_id":45982131847247,"sku":"SH30080.02","price":305.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30080.03HI)","offer_id":45982131880015,"sku":"SH30080.03HI","price":1370.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30080.03IR25-40)","offer_id":45982131912783,"sku":"SH30080.03IR25-40","price":1370.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30080.03)","offer_id":45982131945551,"sku":"SH30080.03","price":1263.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/digi-23352-original-png_a0b1320c-370d-4fbe-b807-2dfa0f1e94f5.png?v=1785958640"},{"product_id":"hyclone-newborn-bovine-calf-serum-us-origin-sh30118-04hi","title":"HyClone™ Newborn Bovine Calf Serum, US Origin","description":"\u003cp\u003eBovine calf serum products are excellent and cost-effective alternatives to fetal bovine serum (FBS). Bovine calf serum products contain exceptionally high levels of transferrin, which can provide three to four times as much available iron as FBS. Key features of HyClone™ Newborn Bovine Calf Serum include:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eComplete traceability back to original source\u003c\/li\u003e\n\u003cli\u003eLow in antibodies and high in growth factors\u003c\/li\u003e\n\u003cli\u003eVirus panel testing according to 9 CFR 113.53\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eHyClone™ Newborn Bovine Calf Serum, US Origin undergoes the same careful collection and processing procedures (including venipuncture) used for our bovine serum products. Newborn calf serum is sourced from animals that are typically less than 10 days old and filtered through three sequential 100 nm (0.1 μm) pore sized-rated filters.\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-17862-pdf\"\u003eData file (PDF)\u003c\/a\u003e\u003c\/li\u003e\u003c\/ul\u003e","brand":"Cytiva","offers":[{"title":"100 mL (SH30118.02HI)","offer_id":45982132535375,"sku":"SH30118.02HI","price":201.0,"currency_code":"ILS","in_stock":true},{"title":"100 mL (SH30118.02)","offer_id":45982132568143,"sku":"SH30118.02","price":111.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30118.03HI)","offer_id":45982132600911,"sku":"SH30118.03HI","price":576.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30118.03IR25-40)","offer_id":45982132633679,"sku":"SH30118.03IR25-40","price":576.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30118.03)","offer_id":45982132666447,"sku":"SH30118.03","price":469.0,"currency_code":"ILS","in_stock":true},{"title":"1000 mL (SH30118.04HI)","offer_id":45982132699215,"sku":"SH30118.04HI","price":1012.0,"currency_code":"ILS","in_stock":true},{"title":"1000 mL (SH30118.04)","offer_id":45982132731983,"sku":"SH30118.04","price":948.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/mALhfPfkBkWRlpJ9xJVwQw-original-png_f7375448-59b3-484b-bb4c-bbc0ad098a9e.png?v=1785958647"},{"product_id":"hyclone-cosmic-calf-serum-u-s-origin-sh30087-04hi","title":"HyClone™ Cosmic Calf Serum, U.S. origin","description":"\u003cp\u003eA bovine calf serum fortified with iron and growth promoting factors for growing a broad spectrum of cell types.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSourced in the USA with complete traceability back to original source\u003c\/li\u003e\n\u003cli\u003eAge of animal at time of collection approximately 16-24 weeks\u003c\/li\u003e\n\u003cli\u003eLow in antibodies and high in growth factors\u003c\/li\u003e\n\u003cli\u003eVirus panel testing according to 9 CFR 113.53\u003c\/li\u003e\n\u003cli\u003eSupplemented with iron and growth-promoting factors\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eHyClone Cosmic Calf serum is a high-performing bovine calf serum that has been fortified with iron and a proprietary blend of growth-promoting factors. The result is a naturally derived, high-quality engineered serum that has demonstrated excellent performance with a broad range of cell types.\u003c\/p\u003e\u003cp\u003eCosmic Calf Serum, U.S. origin is filtered through sequential 100 nm (0.1 µm) pore size-rated filters. Before dispensing, each lot of serum is pooled using true pool technology to ensure uniformity and consistency between bottles.\u003c\/p\u003e\u003cp\u003eAdditional treatments available including heat-inactivation and irradiation. Additional testing, including EMEA-conforming testing, is also available.\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-17549-pdf\"\u003eData file (PDF)\u003c\/a\u003e\u003c\/li\u003e\u003c\/ul\u003e","brand":"Cytiva","offers":[{"title":"100 mL (SH30087.02HI)","offer_id":45982132240463,"sku":"SH30087.02HI","price":194.0,"currency_code":"ILS","in_stock":true},{"title":"100 mL (SH30087.02)","offer_id":45982132273231,"sku":"SH30087.02","price":101.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30087.03HI)","offer_id":45982132305999,"sku":"SH30087.03HI","price":539.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30087.03IR25-40)","offer_id":45982132338767,"sku":"SH30087.03IR25-40","price":539.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30087.03)","offer_id":45982132371535,"sku":"SH30087.03","price":456.0,"currency_code":"ILS","in_stock":true},{"title":"1000 mL (SH30087.04HI)","offer_id":45982132404303,"sku":"SH30087.04HI","price":945.0,"currency_code":"ILS","in_stock":true},{"title":"1000 mL (SH30087.04IR30-45)","offer_id":45982132437071,"sku":"SH30087.04IR30-45","price":945.0,"currency_code":"ILS","in_stock":true},{"title":"1000 mL (SH30087.04IR25-40)","offer_id":45982132469839,"sku":"SH30087.04IR25-40","price":945.0,"currency_code":"ILS","in_stock":true},{"title":"1000 mL (SH30087.04)","offer_id":45982132502607,"sku":"SH30087.04","price":861.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/digi-23386-original-png_f63d3892-8d6f-4ec9-94a1-61a977663512.png?v=1785958644"},{"product_id":"hyclone-iron-supplemented-calf-serum-u-s-origin-sh30072-04ih25-40","title":"HyClone™ Iron-Supplemented Calf Serum, U.S. origin","description":"\u003cp\u003eContains additional iron to boost serum transferrin to physiological levels.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSourced in the USA with complete traceability back to original source\u003c\/li\u003e\n\u003cli\u003eCost-effective alternative to FBS\u003c\/li\u003e\n\u003cli\u003eAge of animal at time of collection approximately 16-24 weeks\u003c\/li\u003e\n\u003cli\u003eLow in antibodies and high in growth factors\u003c\/li\u003e\n\u003cli\u003eVirus panel testing according to 9 CFR 113.53\u003c\/li\u003e\n\u003cli\u003eSupplemented with iron and growth-promoting factors\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003ePurchase orders with specific lot requests, quoted reserves and\/or call off orders should be submitted through \u003ca href=\"\/support\/contact-us\"\u003eCustomer Service.\u003c\/a\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003eHyClone Iron-Supplemented Bovine Calf Serum, U.S. origin is collected by venipuncture from formula-fed veal calves, which produce exceptionally high levels of transferrin. This serum is carefully supplemented with iron to load serum transferrin levels to physiological levels. Bovine calf serum products , when supplemented, can provide three to four times as much available iron as FBS. In many applications, the performance of calf serum will equal or even surpass that of FBS.\u003c\/p\u003e\u003cp\u003eIron-supplemented Bovine Calf Serum, U.S. origin is filtered through sequential 100 nm (0.1 µm) pore size-rated filters. Before dispensing, each lot of serum is pooled using true pool technology to ensure uniformity and consistency between bottles.\u003c\/p\u003e\u003cp\u003eAdditional treatments available including heat-inactivation and irradiation. 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Before dispensing, each lot of serum is pooled using true pool technology to ensure uniformity and consistency between bottles.\u003c\/p\u003e\u003cp\u003eAdditional treatments available including heat-inactivation and irradiation. 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Before dispensing, each lot of serum is pooled using true pool technology to ensure uniformity and consistency between bottles.\u003c\/p\u003e\u003cp\u003eAdditional treatments available including heat-inactivation and irradiation. 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Use with attachment-dependent cell types, including MRC-5, Vero, and CHO K-1 cell lines grown with or without serum. Simply substitute it for porcine trypsin ― there’s no need to adjust your protocol. When stored at -20°C HyrTryp™ has a shelf life of 12 months from the manufacturing date. \u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-46169-pdf\"\u003eData file (PDF)\u003c\/a\u003e\u003c\/li\u003e\u003c\/ul\u003e","brand":"Cytiva","offers":[{"title":"100 mL","offer_id":45982135451727,"sku":"SV30209.01","price":189.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL","offer_id":45982135484495,"sku":"SV30209.02","price":377.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/digi-45482-original-png_7d2a34c5-010d-4937-b3af-415bd8773722.png?v=1785958689"},{"product_id":"hyclone-dulbecco-s-phosphate-buffered-saline-dpbs-sh30378-03","title":"HyClone™ Dulbecco’s Phosphate Buffered Saline (DPBS)","description":"\u003cp\u003eHyClone™ Dulbecco’s Phosphate Buffered Saline (DPBS) is a balanced salt solution designed for diverse cell culture applications. 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DMEM medium composition also includes ferric nitrate, making this cell culture medium an option for certain cell lines requiring iron for cell growth. HyClone DMEM media preparations are available in high or \u003ca href=\"\/shop\/cell-culture-and-fermentation\/media-and-feeds\/classical-media\/hyclone-dulbecco's-modified-eagle-medium-dmem-with-low-glucose-liquid-p-06363\"\u003elow glucose formulations\u003c\/a\u003e, as well as with or without L-glutamine, magnesium, and sodium pyruvate. DMEM formulation options may also include phenol red as a pH indicator. All available DMEM media products contain a sodium bicarbonate buffer with or without HEPES to maintain optimal culture pH.\u003c\/p\u003e\n\n\u003cp\u003eHyClone DMEM raw material components are screened through strict quality control testing for lot-to-lot consistency. DMEM liquid media products are hydrated using purified water and undergo sterile filtration.\u003c\/p\u003e\n\n\u003cp\u003eWhat is DMEM media used for?\u003c\/p\u003e\n\n\u003cp\u003eDMEM is used for a variety of mammalian cell culture manufacturing processes and research applications. DMEM media formulations have supported tumorigenicity studies, virus replication analyses, and investigations into the influence of cell culture media on gene expression. DMEM medium is commonly used for adherent cells and has been the cell culture medium of choice for hybridoma, fibroblast, neuron, and smooth muscle cell lines as well as many other tissues types. DMEM medium is frequently combined with \u003ca href=\"\/shop\/cell-culture-and-fermentation\/sera\/fetal-bovine-serum\/hyclone-characterized-fetal-bovine-serum-fbs-u-s-origin-p-06336\"\u003efetal bovine serum (FBS)\u003c\/a\u003e as DMEM media composition does not include the growth factors, proteins, hormones, or lipids needed to promote cell growth\u003c\/p\u003e","brand":"Cytiva","offers":[{"title":"6 × 1000 mL (SH30285.LS)","offer_id":45982137843791,"sku":"SH30285.LS","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"6 × 1000 mL (SH30081.LS)","offer_id":45992006778959,"sku":"SH30081.LS","price":284.0,"currency_code":"ILS","in_stock":true},{"title":"6 × 1000 mL (SH30022.LS)","offer_id":45992006811727,"sku":"SH30022.LS","price":260.0,"currency_code":"ILS","in_stock":true},{"title":"6 × 1000 mL (SH30243.LS)","offer_id":45992006844495,"sku":"SH30243.LS","price":246.0,"currency_code":"ILS","in_stock":true},{"title":"6 × 500 mL (SH30285.FS)","offer_id":45992006877263,"sku":"SH30285.FS","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"6 × 500 mL (SH30081.FS)","offer_id":45992006910031,"sku":"SH30081.FS","price":185.0,"currency_code":"ILS","in_stock":true},{"title":"6 × 500 mL (SH30243.FS)","offer_id":45992006942799,"sku":"SH30243.FS","price":157.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30284.01)","offer_id":45992006975567,"sku":"SH30284.01","price":48.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30285.01)","offer_id":45992007008335,"sku":"SH30285.01","price":36.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30081.01)","offer_id":45992007041103,"sku":"SH30081.01","price":35.0,"currency_code":"ILS","in_stock":true},{"title":"500 mL (SH30243.01)","offer_id":45992007073871,"sku":"SH30243.01","price":28.0,"currency_code":"ILS","in_stock":true},{"title":"1000 mL (SH30585.02)","offer_id":45992007106639,"sku":"SH30585.02","price":89.0,"currency_code":"ILS","in_stock":true},{"title":"1000 mL (SH30081.02)","offer_id":45992007139407,"sku":"SH30081.02","price":58.0,"currency_code":"ILS","in_stock":true},{"title":"1000 mL (SH30284.02)","offer_id":45992007172175,"sku":"SH30284.02","price":76.0,"currency_code":"ILS","in_stock":true},{"title":"1000 mL (SH30285.02)","offer_id":45992007204943,"sku":"SH30285.02","price":68.0,"currency_code":"ILS","in_stock":true},{"title":"1000 mL (SH30243.02)","offer_id":45992007237711,"sku":"SH30243.02","price":45.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/digi-23404-original-png.png?v=1782740657"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/collections\/TBS8083C.png?v=1791736668","url":"https:\/\/www.danyel.co.il\/collections\/cell-culture-media-and-reagents.oembed","provider":"danyel biotech","version":"1.0","type":"link"}