{"title":"Bioprocessing \u0026 Cell Therapy","description":null,"products":[{"product_id":"nanoassemblr-commercial-formulation-system-flow-kits-1002277","title":"NanoAssemblr™ commercial formulation system flow kits","description":"\u003cp\u003eThe NanoAssemblr™ commercial formulation system flow kit includes the NxGen™ cartridge, pump heads, flow meters, and flow path and can be installed in less than 60 minutes. The flow kit is available as a single-use manufacturing flow kit and a limited, multi-use development flow kit.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSingle-use manufacturing flow kit: Enables manufacturing under cGMP conditions and eliminates the need for sanitizing and cleaning validation. Composed of biocompatible and animal-derived ingredient free materials, the single-use flow kit is fully assembled in a cleanroom and gamma-irradiated (25.0 to 45.0 kGy) for bioburden reduction.\u003c\/li\u003e\n\u003cli\u003eMulti-use development flow kit: Designed for research use only (RUO),  the multi-use flow kit helps facilitate  technology transfer and the production of engineering batches.\u003c\/li\u003e\n\u003cli\u003eSimple installation: The flow kit can be easily installed and ready for formulation quickly, supporting efficient changeover between production batches, minimizing the risk of cross-contamination, and enabling the manufacture of multiple RNA products within the same facility.\u003c\/li\u003e\n\u003cli\u003eIntuitive software: Guides the user through the installation of the flow kit and the entire workflow, reducing the risk of user error.\u003c\/li\u003e\n\u003cli\u003eComplete documentation: Validation guides, certificates of quality, and extractables data are available for all manufacturing flow kits.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cimg alt=\"\" class=\"img-responsive center-block\" src=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/zCleUSjPTs2D_rlsEO_AbA-original-png?v=cdbea092\" style=\"max-width: 800px;\"\u003e\u003c\/p\u003e\n\n\u003cp\u003eSchematic of the single-use flow path. The flow kit includes the NxGen™ cartridge, pump heads, flow meters, and flow path.\u003c\/p\u003e","brand":"Cytiva","offers":[{"title":"GMP manufacturing (1002279)","offer_id":45982004805711,"sku":"1002279","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"GMP manufacturing (1002280)","offer_id":45982004838479,"sku":"1002280","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"RUO (1002277)","offer_id":45982004871247,"sku":"1002277","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"RUO (1002278)","offer_id":45982004904015,"sku":"1002278","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/6tpExERRRvu3Ohc7Mee-sw-original-png_7d0e71c7-60db-4f3b-a903-b0116573d1ab.png?v=1785956279"},{"product_id":"hyclone-adcf-antifoam-solution-sh30897-01","title":"HyClone™ ADCF antifoam solution","description":"\u003cp\u003eHyClone™ ADCF antifoam irradiated solution products have 3% active simethicone and has been shown to effectively prevent foam from occurring in cell culture systems, as well as to quickly eliminate foam already formed.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eIrradiated Antifoam effectively prevents and dissipates foaming in cell culture systems.\u003c\/li\u003e\n\u003cli\u003eProvided in easy-to-use single-use bags.\u003c\/li\u003e\n\u003cli\u003eDesigned with tubing lines and fittings to enable easy connection and delivery to any cell culture system (customization possible).\u003c\/li\u003e\n\u003cli\u003eHyClone™ Antifoam is an emulsion with ~3% active simethicone.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThe products are delivered in single‑use bags designed with tubing lines and fittings to enable easy connection and delivery to various cell culture systems.  \u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-17826-pdf\"\u003eData file (PDF)\u003c\/a\u003e\u003c\/li\u003e\u003c\/ul\u003e","brand":"Cytiva","offers":[{"title":"1 × 500 mL","offer_id":45982005690447,"sku":"SH30897.01","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"8 × 500 mL","offer_id":45982005723215,"sku":"SH30897.04","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/digi-26792-original-png_e5bf1331-ec74-40b5-af28-d4c4eb8c9757.png?v=1785956329"},{"product_id":"connector-25-mm-tc-9-5-mm-hose-barb-56410980","title":"Connector 25 mm TC - 9.5 mm hose barb","description":"\u003cp\u003eSanitary to 3\/8 in hose barb adapter\u003c\/p\u003e","brand":"Cytiva","offers":[{"title":"25 mm (0.5\") TC 9.5 mm (0.375\") barb","offer_id":45982008901711,"sku":"56410980","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/digi-4425-original-png_dbfab000-9446-4ed5-add8-5f8d9c0882a7.png?v=1785956447"},{"product_id":"connector-25-mm-tc-6-4-mm-barb-56410979","title":"Connector 25 mm TC  - 6.4 mm barb","description":"\u003cp\u003eTCX HB, kit\u003c\/p\u003e","brand":"Cytiva","offers":[{"title":"Default Title","offer_id":45982008967247,"sku":"56410979","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/digi-4424-original-png_f305489b-05cf-4baf-9219-895cc0119141.png?v=1785956450"},{"product_id":"female-luer-male-luer-connector-56410577","title":"Female luer-male luer connector","description":"\u003cp\u003eFemale luer x male luer adapter, 10\u003c\/p\u003e","brand":"Cytiva","offers":[{"title":"10","offer_id":45982009000015,"sku":"56410577","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/digi-4392-original-png_06b312e8-4254-4373-80b3-e87c9addbb6d.png?v=1785956456"},{"product_id":"cytodex-1-gamma-microcarriers-sterilized-dry-powder-17548701","title":"Cytodex™ 1 Gamma microcarriers (sterilized, dry powder)","description":"\u003cp\u003eMicrocarrier for general use in sterilized dry powder form.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eGamma-sterilized and ready to use for quick culture start-up.\u003c\/li\u003e\n\u003cli\u003eDelivered in a convenient, single-use container system for easy transfer to various cell culture vessels.\u003c\/li\u003e\n\u003cli\u003eSupplied dry to save storage space and facilitate transportation.\u003c\/li\u003e\n\u003cli\u003eEnable culturing of anchorage-dependent cells in single-use bioreactor to eliminate the need for cleaning and cleaning validation.\u003c\/li\u003e\n\u003cli\u003eSupported by extensive product documentation to facilitate regulatory filing.\u003c\/li\u003e\n\u003cli\u003eSerum-free function testing to ensure performance\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eA general-purpose microcarrier\u003c\/p\u003e\n\n\u003cp\u003eSterilized Cytodex 1 Gamma is a general-purpose microcarrier particularly suitable for most established cell lines and for production of viruses or cell products from cultures of primary cells and normal diploid cell strains.\u003c\/p\u003e\n\n\u003cp\u003eCytodex 1 Gamma is designed by substituting a cross-linked dextran matrix with positively charged N, N-diethylaminoethyl (DEAE) groups distributed throughout the matrix.\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"\/solutions\/bioprocessing\/knowledge-center\/Scalable-ADCF-virus-production\"\u003eLearn how Cytodex 1 microcarriers were used in scalable ADCF virus production using HyClone VaccineXpress medium \u003c\/a\u003e\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-17654-pdf\"\u003eData file (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/d3.cytivalifesciences.com\/prod\/IFU\/29115815.pdf\"\u003eInstructions for use (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Cytiva","offers":[{"title":"3 kg","offer_id":45982014799951,"sku":"17548703","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"30 g","offer_id":45982014832719,"sku":"17548701","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"300 g","offer_id":45982014865487,"sku":"17548702","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/digi-3794-original-png.png?v=1782739468"},{"product_id":"cytodex-3-gamma-microcarriers-sterilized-dry-powder-17548802","title":"Cytodex™ 3 Gamma microcarriers (sterilized, dry powder)","description":"\u003cp\u003eThe microcarrier of choice for cells that are difficult to culture in vitro - particularly for cells with an epithelial-like morphology.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eGamma-sterilized and ready to use for quick culture start-up.\u003c\/li\u003e\n\u003cli\u003eDelivered in a convenient, single-use container system for easy transfer to various cell culture vessels.\u003c\/li\u003e\n\u003cli\u003eSupplied dry to save storage space and facilitate transportation.\u003c\/li\u003e\n\u003cli\u003eEnable culturing of anchorage-dependent cells in single-use bioreactor to eliminate the need for cleaning and cleaning validation.\u003c\/li\u003e\n\u003cli\u003eSupported by extensive product documentation to facilitate regulatory filing.\u003c\/li\u003e\n\u003cli\u003eSerum-free function testing to ensure performance.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eSuccessful serial subcultivation protocols\u003c\/p\u003e\n\u003cp\u003eCytodex 3 Gamma is designed by chemically coupling of a thin layer of denatured porcine collagen type 1 to the cross-linked dextran matrix. As the collagen surface layer can be digested by a variety of proteolytic enzymes, harvest of such cells from the microcarriers can be performed with maintained high cell viability and membrane integrity. This feature of Cytodex 3 Gamma is beneficial in the development of successful serial subcultivation protocols for scaling up culture volumes.\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-17654-pdf\"\u003eData file (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/d3.cytivalifesciences.com\/prod\/IFU\/29115815.pdf\"\u003eInstructions for use (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Cytiva","offers":[{"title":"3 kg","offer_id":45982014767183,"sku":"17548803","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"30 g","offer_id":45991796932687,"sku":"17548801","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"300 g","offer_id":45991796965455,"sku":"17548802","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/digi-3794-original-png_74c7a945-17d3-45ab-a166-c91be63416d1.png?v=1782905956"},{"product_id":"cytodex-3-microcarriers-dry-powder-17048501","title":"Cytodex™ 3 microcarriers (dry powder)","description":"\u003cp\u003eThe microcarrier of choice for cells that may be difficult to culture in vitro .\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eDesigned for culture of primary cells or those with an epithelioid morphology, especially cells with low plating-efficiency or differentiated or sensitive cell-types which are normally difficult to grow, e.g. hepatocytes, endocrine cells.\u003c\/li\u003e\n\u003cli\u003eContains a layer of acid-denatured porcine collagen (gelatin) on the surface of the microporous matrix.\u003c\/li\u003e\n\u003cli\u003eDesigned to yield harvested cells of the highest viability.\u003c\/li\u003e\n\u003cli\u003eTransparent for easy microscopic examination of attached cells.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eMicrocarrier culture\u003c\/p\u003e\n\u003cp\u003eMicrocarrier culture is a technique which makes possible the practical high yield culture of anchorage-dependent cells. Cytodex has been specifically developed for the culture of a wide range of animal cells in culture volumes ranging from a few ml to more than 6000 L. Using Cytodex in simple suspension culture systems provides yields of several million cells per mL.\u003c\/p\u003e\n\u003cp\u003eFormation\u003c\/p\u003e\n\u003cp\u003eFormed by chemically coupling a thin layer of denatured collagen to the cross-linked dextran matrix, this is the microcarrier of choice for cells that may be difficult to culture \u003ci\u003ein vitro\u003c\/i\u003e, and particularly for cells with an epithelial like morphology.\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-12160-pdf\"\u003eData file (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/d3.cytivalifesciences.com\/prod\/IFU\/18111979.pdf\"\u003eInstructions for use (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Cytiva","offers":[{"title":"2.5 kg","offer_id":45982015553615,"sku":"17048525","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"5 kg","offer_id":45982015586383,"sku":"17048504","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"10 g","offer_id":45982015619151,"sku":"17048501","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"100 g","offer_id":45982015651919,"sku":"17048502","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"500 g","offer_id":45982015684687,"sku":"17048503","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/digi-5457-original-png_075e6e08-2a48-47c5-bd63-84e693ec1d29.png?v=1785956721"},{"product_id":"cytodex-1-microcarriers-dry-powder-17044802","title":"Cytodex™ 1 microcarriers (dry powder)","description":"\u003cp\u003eA general-purpose microcarrier for most established, anchorage-dependent cell lines.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eGeneral-purpose microcarrier for most established, anchorage-dependent cell lines.\u003c\/li\u003e\n\u003cli\u003eContains positive charges throughout the microporous matrix.\u003c\/li\u003e\n\u003cli\u003eTransparent for easy microscopic examination of attached cells.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eIt is particularly suitable for most established cell lines and for production of viruses or cell products from cultures of primary cells and normal diploid cell strains.\u003c\/p\u003e\u003cp\u003eHigh yield culture of anchorage-dependent cells\u003c\/p\u003e\u003cp\u003eMicrocarrier culture is a technique which makes possible the practical high yield culture of anchorage-dependent cells. Cytodex has been specifically developed for the culture of a wide range of animal cells in culture volumes ranging from a few mL to more than 6000 L. Using Cytodex in simple suspension culture systems provides yields of several million cells per mL.\u003c\/p\u003e\u003cp\u003eSuitable for most established cell lines\u003c\/p\u003e\u003cp\u003eFormed by substituting a cross-linked dextran matrix with positively charged DEAE* groups distributed throughout the matrix, is a general purpose microcarrier. It is particularly suitable for most established cell lines and for production of viruses or cell products from cultures of primary cells and normal diploid cell strains.\u003c\/p\u003e\u003cp\u003e* N, N-diethylaminoethyl\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-12160-pdf\"\u003eData file (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/d3.cytivalifesciences.com\/prod\/IFU\/18111979.pdf\"\u003eInstructions for use (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Cytiva","offers":[{"title":"2.5 kg","offer_id":45982019125327,"sku":"17044825","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"5 kg","offer_id":45982019158095,"sku":"17044804","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"25 g","offer_id":45982019190863,"sku":"17044801","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"100 g","offer_id":45982019223631,"sku":"17044802","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"500 g","offer_id":45982019256399,"sku":"17044803","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/digi-5450-original-png_161077a8-8de5-430e-9c2e-86c300ee8dea.png?v=1785956869"},{"product_id":"female-luer-female-luer-connector-56411157","title":"Female luer-female luer connector","description":"\u003cp\u003eFemale to female luer fItting\u003c\/p\u003e","brand":"Cytiva","offers":[{"title":"10","offer_id":45982028398671,"sku":"56411157","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/digi-4727-original-png_9b191cb5-1606-4570-9415-9dd3edd82352.png?v=1785957190"},{"product_id":"hyclone-actipro-cell-culture-media-sh31037-02","title":"HyClone™ ActiPro™ cell culture media","description":"\u003cp\u003eHyClone™ ActiPro™ cell culture media has been formulated to provide high yields of recombinant proteins in bioprocesses using Chinese hamster ovary (CHO) cell lines. The cultured medium is chemically defined, animal-derived component-free (ADCF), and optimized for high-yield protein expression and production in batch or CHO fed-batch cell culture processes.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eDemonstrates high yields of recombinant protein\u003c\/li\u003e\n\u003cli\u003eDoes not contain hypoxanthine and thymidine (HAT supplement)\u003c\/li\u003e\n\u003cli\u003eChemically defined ADCF mAb media formulation\u003c\/li\u003e\n\u003cli\u003eProduction medium for batch or fed-batch fermentation processes\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eHyClone™ ActiPro™ cell culture medium is available in both liquid and powder forms for cell culture bioprocesses. This chemically defined medium is intended for use in combination with \u003ca href=\"\/shop\/cell-culture-and-fermentation\/media-and-feeds\/specialty-media\/hyclone-actism-cell-culture-media-p-05498\"\u003eHyClone™ ActiSM™ medium\u003c\/a\u003e and \u003ca href=\"\/shop\/cell-culture-and-fermentation\/reagents-and-supplements\/feed-supplements\/hyclone-cell-boost-7a-supplement-p-06179\"\u003eCell Boost™ 7a\u003c\/a\u003e and \u003ca href=\"\/shop\/cell-culture-and-fermentation\/media-and-feeds\/feed-supplements\/hyclone-cell-boost-7b-supplement-p-06306\"\u003eCell Boost™ 7b supplements\u003c\/a\u003e. ActiPro™ media and supplements are formulated for industrial production of recombinant proteins, including those requiring complex post-translational modifications and correct protein folding. In addition, this engineered ActiPro™ system of media and supplements can significantly reduce production process time.\u003c\/p\u003e\n\n\u003cp\u003eThe ActiPro™ system is suitable for general cell culture biomanufacturing with CHO cell lines such as CHO-GS, CHO-K1, CHO-DG44, and CHO-S. ActiPro™ cell culture media and supplements were designed with adaptation and CHO protein production in mind. ActiPro™ media and supplements are balanced formulations of amino acids, vitamins, salts, trace elements, and other components, meeting the metabolic needs of CHO cells in production. The cell culture system does not contain peptides, hydrolysates, phenol red, 2-mercaptoethanol, or growth factors such as insulin, to ensure batch-to-batch consistency and increased cell culture bioprocess efficiency. For fast-growing CHO cells with higher carbon consumption, glucose supplementation is needed.\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-17793-pdf\"\u003eData file (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/d3.cytivalifesciences.com\/prod\/IFU\/29871627.pdf\"\u003eInstructions for use (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Cytiva","offers":[{"title":"Liquid \/ 500 mL","offer_id":45982029676623,"sku":"SH31039.01","price":247.0,"currency_code":"ILS","in_stock":true},{"title":"Liquid \/ 1000 mL","offer_id":45982029709391,"sku":"SH31039.02","price":411.0,"currency_code":"ILS","in_stock":true},{"title":"Powder \/ 5 L","offer_id":45982029742159,"sku":"SH31037.01","price":1106.0,"currency_code":"ILS","in_stock":true},{"title":"Powder \/ 10 L","offer_id":45982029774927,"sku":"SH31037.02","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/digi-26596-original-png_a49cf8df-26bd-4059-bced-3a64de4be840.png?v=1785957246"},{"product_id":"readycircuit-single-use-jumper-tube-sets-sterilenz-tc-connectors-12410147","title":"ReadyCircuit single-use jumper tube sets: SterilEnz TC connectors","description":"\u003cp\u003eReadyCircuit jumper tube set with C-Flex® ID tubing terminating with ReadyMate to SterilEnz® TC connectors.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ePort tubing and ReadyMate single-use connectors are preconfigured into ReadyCircuits to connect with a variety of ReadyCircuit process components.\u003c\/li\u003e\n\u003cli\u003eJumper assemblies are supplied gamma-irradiated with a certificate of quality.\u003c\/li\u003e\n\u003cli\u003eC-Flex® jumpers enable tube sealing\/fusing and this facilitates aseptic connections pre- or post-processing.\u003c\/li\u003e\n\u003cli\u003eReinforced silicone jumpers enable operating pressures to 4 barg (60 psig).\u003c\/li\u003e\n\u003cli\u003eSilicone pump tubing jumpers enable the use of peristaltic pumps.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eBasic tubing assemblies consist of lengths of tubing with ReadyMate single-use connectors at each end. Other ReadyCircuit tubing assemblies include tubing or asingle-use connectors integrated with components such as Ts, Ys, reducers, sensors and filters.\u003c\/p\u003e\u003cp\u003eA variety of tubing assemblies\u003c\/p\u003e\u003cp\u003eMost ReadyCircuit assemblies use ReadyMate single-use connectors. These connectors enable aseptic system connections in a matter of seconds. 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Port configuration varies by bag type.\u003c\/p\u003e\n\n\u003cp\u003eReadyCircuit™ bag assembly types with ReadyKleer™ film\u003c\/p\u003e\n\n\u003cp\u003eScale-up capability is offered by ReadyCircuit™ bags, for maintained continuity in your development efforts. Bag types include sample bags for small-volume applications, 50 L horizontal pillow bag, 1, 5, 10, and 20 L 2-D hanging bags for use on mobile carts or trays, and 50, 100, 200, 500 and 1000 L 3-D bags for large-scale production.\u003c\/p\u003e\n\n\u003cp\u003eReadyKart mobile processing stations and supporting hardware are optimized to enable organization of ReadyCircuit™ assemblies into an efficient process scheme.\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/0WEtLt702EmgaMOCzRY-wA-pdf\"\u003eData file (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-16382-pdf\"\u003eInstructions for use (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Cytiva","offers":[{"title":"2 ports \/ 200 ml","offer_id":45982048059471,"sku":"12410226","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"2 ports \/ 500 mL","offer_id":45982048092239,"sku":"12410227","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"3 ports \/ 1 L","offer_id":45982048125007,"sku":"12410218","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"3 ports \/ \u003c 5 L","offer_id":45982048157775,"sku":"12410220","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"3 ports \/ 10 L","offer_id":45982048190543,"sku":"12410222","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"3 ports \/ 20 L","offer_id":45982048223311,"sku":"12410224","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"3 ports \/ 50 L","offer_id":45982048256079,"sku":"12410228","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"4 ports \/ 1 L","offer_id":45982048288847,"sku":"12410219","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"4 ports \/ \u003c 5 L","offer_id":45982048321615,"sku":"12410221","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"4 ports \/ 10 L","offer_id":45982048354383,"sku":"12410223","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"4 ports \/ 20 L","offer_id":45982048387151,"sku":"12410225","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"4 ports \/ 50 L","offer_id":45982048419919,"sku":"12410229","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/digi-9442-original-png_0be8693a-f14f-4166-baca-afbc4f39e897.png?v=1785957868"},{"product_id":"readytoprocess-mixer-accessories-28411575","title":"ReadyToProcess™ mixer accessories","description":"\u003cp\u003eCytiva offers several accessories for the ReadyToProcess™ Mixer, which can be purchased in kit form or separately. 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Other ReadyCircuit tubing assemblies include tubing or single-use connectors integrated with components such as Ts, Ys, reducers, sensors and filters.\u003c\/p\u003e\u003cp\u003eA variety of tubing assemblies\u003c\/p\u003e\u003cp\u003eYou can select and order a combination of ReadyCircuit tubing assemblies that meet specific processing needs.\u003c\/p\u003e\u003cp\u003eIntegration capability\u003c\/p\u003e\u003cp\u003eSome ReadyCircuit tubing assemblies include TC and Steam-Thru adaptors commonly used to connect disposable fluid paths to stainless steel process equipment.\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-15551-pdf\"\u003eData file (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-16382-pdf\"\u003eInstructions for use (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Cytiva","offers":[{"title":"24\"","offer_id":45982049861711,"sku":"28979438","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Standard (28979470)","offer_id":45982049894479,"sku":"28979470","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Standard (28979434)","offer_id":45982049927247,"sku":"28979434","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Standard (28979432)","offer_id":45982049960015,"sku":"28979432","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Standard (28979436)","offer_id":45982049992783,"sku":"28979436","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Standard (28979437)","offer_id":45982050025551,"sku":"28979437","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/69c2a45ee6724ce6b5869640310fc044_c0068a0c-cd59-4882-b332-109d471ad662.png?v=1785956229"},{"product_id":"readycircuit-single-use-sensor-assemblies-28979471","title":"ReadyCircuit™ single-use sensor assemblies","description":"\u003cp\u003eSingle-use tubing assemblies integrated with sensors for temperature, pressure and conductivity and compatible with SciLog BioProcessing Systems SciTemp™, SciPres™, and SciCon™ monitors (part numbers 080-790, 080-690, and 080-590, respectively).\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSensors and ReadyMate single-use connectors are preconfigured into sensor assemblies for immediate use in a ReadyCircuit assembly.\u003c\/li\u003e\n\u003cli\u003eSensors assemblies are supplied gamma-irradiated with a certificate of quality.\u003c\/li\u003e\n\u003cli\u003eAccurate and reliable pressure, temperature, and conductivity sensors with easy connection to read-out monitors.\u003c\/li\u003e\n\u003cli\u003eSensor data can be logged via the sensor monitor interfaces.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eSensor assemblies\u003c\/p\u003e\u003cp\u003eReadyCircuit Sensors are preconfigured assemblies of standard temperature, pressure and conductivity sensors, ReadyMate single-use connectors, and where applicable, reinforced silicone tubing.\u003c\/p\u003e\u003cp\u003eFluid path sizing\u003c\/p\u003e\u003cp\u003eSome of the standard components include 3\/8 inch pressure, temperature, and conductivity sensors with silicone tubing, and 3\/8 inch ReadyMate connectors. The larger ¾ inch diameter sensors utilize direct fractional T\/C ReadyMate connections.\u003c\/p\u003e\u003cp\u003eMonitoring systems\u003c\/p\u003e\u003cp\u003eAll sensors are compatible with their relevant \"parent\" SciLog, SciTemp, SciPres, or SciCon monitors.\u003c\/p\u003e\u003cp\u003eSensor connector and cables are lockable and waterproof.\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-15551-pdf\"\u003eData file (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-16382-pdf\"\u003eInstructions for use (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Cytiva","offers":[{"title":"Sensor Assembly with a Scilog pressure sensor and 6 in (152 mm) of AdvantaPure Reinforced Silicone 0.375 in (10 mm) ID tubing terminating with ReadyMate connectors.","offer_id":45982050123855,"sku":"28979471","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Sensor Assembly, SciLog pressure sensor","offer_id":45982050156623,"sku":"12410233","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Sensor Assembly with a Scilog conductivity sensor and 6 in (152 mm) of AdvantaPure Reinforced Silicone 0.375 in (10 mm) ID tubing terminating with ReadyMate connectors.","offer_id":45982050189391,"sku":"28979440","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Sensor Assembly, SciLog temperature sensor, 6\" of AdvantaPure reinforced silicone 0.375\"","offer_id":45982050222159,"sku":"28979439","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Sensor Assembly, SciLog conductivity sensor","offer_id":45982050254927,"sku":"12410243","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Sensor Assembly, SciLog temperature sensor","offer_id":45982050287695,"sku":"12410238","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/69c2a45ee6724ce6b5869640310fc044_c0068a0c-cd59-4882-b332-109d471ad662.png?v=1785956229"},{"product_id":"xda-exhaust-filter-tube-set-meissner-cf2vtv0-2-33b1-888-0417","title":"XDA Exhaust Filter Tube Set (Meissner CF2VTV0.2-33B1)","description":null,"brand":"Cytiva","offers":[{"title":"Default Title","offer_id":45982050418767,"sku":"888-0417","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/69c2a45ee6724ce6b5869640310fc044_c0068a0c-cd59-4882-b332-109d471ad662.png?v=1785956229"},{"product_id":"readycircuit-single-use-jumper-t-manifolds-12410182","title":"ReadyCircuit™ single-use jumper T manifolds","description":"\u003cp\u003eReadyCircuit jumper T manifolds, in 3 port sizes, with C-Flex® tubing terminating with ReadyMate single-use connectors.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e3, 4, and 6-port tubing versions terminating with ReadyMate single-use connectors.\u003c\/li\u003e\n\u003cli\u003eJumper assemblies are supplied gamma-irradiated with a certificate of quality.\u003c\/li\u003e\n\u003cli\u003eC-Flex® jumpers enable tube sealing\/fusing and this facilitates aseptic connections pre- or post-processing.\u003c\/li\u003e\n\u003cli\u003eReinforced silicone jumpers enable operating pressures to 4 barg (60 psig).\u003c\/li\u003e\n\u003cli\u003eSilicone pump tubing jumpers enable the use of peristaltic pumps.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eTubing jumper assemblies\u003c\/p\u003e\u003cp\u003eBasic tubing assemblies consist of lengths of tubing with ReadyMate single-use connectors at each end. 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The genderless design facilitates connection simplicity, reduces complexity of inventory, and creates flexibility in the assembly of single use flow paths.\u003c\/p\u003e\u003cp\u003eReadyKart mobile processing stations and supporting hardware are optimized to enable organization of ReadyCircuit assemblies into an efficient process scheme.\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-15551-pdf\"\u003eData file (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-16382-pdf\"\u003eInstructions for use (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Cytiva","offers":[{"title":"ReadyCircuit Jumper Y Manifold, 3 ports, 6\" of AdvantaPure reinforced silicone 0.75\"","offer_id":45982098587727,"sku":"12410196","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"ReadyCircuit Jumper Y Manifold, 3 ports, 6\" of  0.375\" tubing","offer_id":45982098620495,"sku":"12410190","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"ReadyCircuit Jumper Y Manifold, 3 ports, 6\" of  0.75\" tubing","offer_id":45982098653263,"sku":"12410192","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"ReadyCircuit Jumper Y Manifold, 3 ports, 6\" of  0.25\" tubing","offer_id":45982098686031,"sku":"12410189","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"ReadyCircuit Jumper Y Manifold, 3 ports, 6\" of AdvantaPure reinforced silicone 0.375\"","offer_id":45982098718799,"sku":"12410194","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"ReadyCircuit Jumper Y Manifold, 3 ports,  6\" of AdvantaPure reinforced silicone 0.5\"","offer_id":45982098751567,"sku":"12410195","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"ReadyCircuit Jumper Y Manifold, 3 ports, 6\" of AdvantaPure reinforced silicone 0.25\"","offer_id":45982098784335,"sku":"12410193","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"ReadyCircuit Jumper Y Manifold, 3 ports, 6\" of  0.5\" tubing","offer_id":45982098817103,"sku":"12410191","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/c6L6Q3p9RVeBvuGanVU5Tg-original-png_b3d74f39-d122-4253-af09-c063e7f4f6d9.png?v=1785958263"},{"product_id":"readykart-mobile-processing-spare-parts-28977918","title":"ReadyKart Mobile Processing Spare Parts","description":"\u003cul\u003e\n\u003cli\u003eQuick and convenient setup of fluid processing equipment saves time.\u003c\/li\u003e\n\u003cli\u003eNesting capabilities with hose\/tubing routing enables integration of multistep processes.\u003c\/li\u003e\n\u003cli\u003eAvailable components and optional equipment supports a wide range of fluid processing setups.\u003c\/li\u003e\n\u003cli\u003eBag holders rotate in 90° increments to accommodate bag style and equipment configuration.\u003c\/li\u003e\n\u003cli\u003eBag holders are height adjustable to accommodate any size pillow bags up to 20 L, including non-Cytiva bags.\u003c\/li\u003e\n\u003cli\u003eReplaceable shelves, with cutouts, accept bins that hold 100 and 200 L 3-D bags.\u003c\/li\u003e\n\u003cli\u003ePush handles on both ends of cart provide control during transportation.\u003c\/li\u003e\n\u003cli\u003eRemovable plastic end plate restricts, shields, or allows access to processing equipment. Endplate includes six process-tubing routing ports.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eReadyKart stations are manufactured out of 304 stainless steel parts to minimize maintenance and provide long service life. Two 360° heavy-duty casters make the cart easy to move even when fully loaded. The cart is available in two optimized sizes that fit through standard doors.\u003c\/p\u003e\u003cp\u003eReadyKart Mobile Processing stations are designed for scientists, process engineers, and laboratory technicians who need to configure fluid processing systems for product and process development or pilot manufacturing.\u003c\/p\u003e\u003cp\u003eWhen used with Cytiva's family of ReadyToProcess components, users can quickly configure a wide range of sterile and disposable fluid processing systems. ReadyKart stations allow for the ergonomic placement of equipment so that you can perform your tasks faster and better.\u003c\/p\u003e\u003cp\u003eCytiva manufactures ReadyKart Mobile Processing Station in two sizes—standard and mini. Each size includes two configurations: (1) the base framework with wheels to which you add individual components to meet your specific requirements; and (2) a fully configured cart that includes the framework and components required for fluid processing applications. Fully configured carts include an arm clamp assembly to suspend bags (two on a standard cart), filter holder, solid shelves, and a protective end panel.\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-15556-pdf\"\u003eData file (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-16381-pdf\"\u003eInstructions for use (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Cytiva","offers":[{"title":"ReadyKart Arm Gas Spring, (replacement part)","offer_id":45982098915407,"sku":"28977918","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/digi-4481-original-png_dcc609e9-a79a-4962-b873-8ca476a91857.png?v=1785958268"},{"product_id":"nanoassemblr-spark-nanoparticle-formulation-system-29873660","title":"NanoAssemblr™ Spark™ nanoparticle formulation system","description":"\u003cp\u003eThe NanoAssemblr™ Spark™ nanoparticle formulation system enables the production of nanoparticle formulation in volumes ranging from 25 – 250 μL, ideal for discovery and screening that involves scarce or expensive nucleic acids and nanoparticle excipients.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eRobust process and feedback - Electronic control minimizes batch-to-batch and user variability while providing real-time feedback to help optimize your formulation\u003c\/li\u003e\n\u003cli\u003eRapid production - Simply pipette starting materials into wells, and with the press of a button, the formulation is ready in seconds, allowing hundreds of formulations to be made in just a few hours\u003c\/li\u003e\n\u003cli\u003eWorkflow integration - Designed for operation in a sterile biosafety hood, the formulations can be made on-demand and applied to cells in culture\u003c\/li\u003e\n\u003cli\u003eScalable – Leveraging NxGen™ mixing technology, the formulations can be seamlessly scaled across the NanoAssemblr™ platform, accelerating future development\u003c\/li\u003e\n\u003cli\u003eExceptional sample recovery - Advanced NxGen™ mixing technology allows the formulation of microliter volumes with near complete sample recovery\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003ciframe allowfullscreen=\"\" allowtransparency=\"true\" class=\"vidyard_iframe\" frameborder=\"0\" height=\"360\" referrerpolicy=\"no-referrer-when-downgrade\" scrolling=\"no\" src=\"\/\/play.vidyard.com\/e2Cx2nPQsCRuTmpj4QtSVj.html?\" title=\"The NanoAssemblr® Spark™ | Robust Low Volume RNA-Lipid Nanoparticle Formulation\" width=\"640\"\u003e\u003c\/iframe\u003e\u003c\/p\u003e\n\n\u003cp\u003eThe Nanoassemblr™ Spark™ system enables robust low-volume RNA-lipid nanoparticle (LNP) formulations ideal for drug discovery and early preclinical development.\u003c\/p\u003e\n\n\u003cp\u003eSimple, easy workflow\u003c\/p\u003e\n\n\u003cp\u003eFormulations on the Nanoassemblr™ Spark™ system are ready in seconds. Plus, they can be made on-demand in a sterile hood for immediate cell culture applications.\u003c\/p\u003e\n\n\u003cp\u003e\u003cimg class=\"img-responsive center-block\" src=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/FRCKbj4TS7qPB9bLbabS4w-original-png\" style=\"width:800px;\"\u003e\u003c\/p\u003e\n\n\u003cp\u003eApplications\u003c\/p\u003e\n\n\u003cul\u003e\n\t\u003cli\u003eNucleic acid delivery and screening\u003c\/li\u003e\n\t\u003cli\u003eNanoparticle design and screening\u003c\/li\u003e\n\t\u003cli\u003eDrug discovery and target validation\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eRelated products\u003c\/p\u003e\n\n\u003cp\u003eNanoAssemblr™ Spark™ cartridges\u003c\/p\u003e\n\n\u003cp\u003e\u003ca href=\"\/shop\/lipid-nanoparticle-instruments-and-reagents\/nanoparticle-formulation-cartridges-and-flow-kits\/nanoassemblr-spark-cartridges-p-45323\"\u003eNanoAssemblr™ Spark™ cartridges\u003c\/a\u003e are equipped with NxGen™ mixing technology. No cleaning or validation is required: cartridges are single-use and gamma-irradiated.\u003c\/p\u003e\n\n\u003cp\u003e\u003cimg class=\"img-responsive center-block\" src=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/CR-m_hKvRfWYf1zpNQg97w-original\" style=\"width:500px;\"\u003e\u003c\/p\u003e\n\n\u003cp\u003ePressure test cartridges\u003c\/p\u003e\n\n\u003cp\u003ePressure test cartridges can be used to ensure optimal functioning of your system. Read the user guide below to learn more.\u003c\/p\u003e\n\n\u003cp\u003e\u003cimg class=\"img-responsive center-block\" src=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/mi2IJ5XGSdOsAsDWW83Kig-original\" style=\"width:500px;\"\u003e\u003c\/p\u003e\n\n\u003cp\u003eReagents\u003c\/p\u003e\n\n\u003cp\u003eExpand formulation capabilities and advance genomic medicines with specialized accessories and optimized \u003ca href=\"\/shop\/lipid-nanoparticle-instruments-and-reagents\/lipid-nanoparticle-reagents?sort=NameAsc\u0026amp;chunk=1\"\u003eLNP delivery reagents\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003cdiv class=\"row\"\u003e\n\u003cdiv class=\"col-sm-6\"\u003e\n\u003cp\u003e\u003cimg class=\"img-responsive center-block\" src=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/m2iEUkZ6Q4WprDPdvIMNlg-original\" style=\"width:500px;\"\u003e\u003c\/p\u003e\n\n\u003cp\u003eGenVoy-ILM™ T Cell Kit for mRNA\u003c\/p\u003e\n\n\u003cp\u003eThe GenVoy-ILM™ T Cell Kit for mRNA is a lipid nanoparticle reagent mix optimized for the delivery of mRNA into activated primary human T cells using mRNA-LNP.\u003c\/p\u003e\n\u003c\/div\u003e\n\n\u003cdiv class=\"col-sm-6\"\u003e\n\u003cp\u003e\u003cimg class=\"img-responsive center-block\" src=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/TvW056e8R664GV15GQ0ORQ-original\" style=\"width:500px;\"\u003e\u003c\/p\u003e\n\n\u003cp\u003eCytiva CD34+ HSC LNP kit, 100 μL\u003c\/p\u003e\n\n\u003cp\u003eThe Cytiva CD34+ HSC LNP kit, 100 μL enables the delivery of RNA into hematopoietic stem cells for \u003cem\u003eex vivo\u003c\/em\u003e gene delivery and knockout.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"Cytiva","offers":[{"title":"NanoAssemblr Spark Demo Kit - mRNA with Cartridges","offer_id":45982098948175,"sku":"29873660","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"NanoAssmblr™ Spark™ instrument","offer_id":45982098980943,"sku":"NIS0001","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/a6q30OH5SpquzWFcTYDDBw-original-png_125fc253-86d7-4f19-92b0-38ff18ff2341.png?v=1785958272"},{"product_id":"single-use-sample-manifold-888-0431","title":"Single use sample manifold","description":null,"brand":"Cytiva","offers":[{"title":"Default Title","offer_id":45982099079247,"sku":"888-0431","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/69c2a45ee6724ce6b5869640310fc044_c0068a0c-cd59-4882-b332-109d471ad662.png?v=1785956229"},{"product_id":"clamp-tool-assembly-stf-wet-29011018","title":"Clamp Tool Assembly-STF-Wet","description":"\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-16206-pdf\"\u003eData file (PDF)\u003c\/a\u003e\u003c\/li\u003e\u003c\/ul\u003e","brand":"Cytiva","offers":[{"title":"Default Title","offer_id":45982099210319,"sku":"29011018","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/69c2a45ee6724ce6b5869640310fc044_c0068a0c-cd59-4882-b332-109d471ad662.png?v=1785956229"},{"product_id":"readycircuit-single-use-3-d-bag-assemblies-12410208","title":"ReadyCircuit™ single-use 3-D bag assemblies","description":"\u003cp\u003eReadyCircuit™ single-use 3-D bag assemblies are designed for large-scale bioprocessing applications in 50, 100, 200, 500 and 1000 L sizes. They allow quick configuration and assembly of a wide range of sterile, fluid-processing circuits.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ePort tubing and ReadyMate disposable single-use connectors are preconfigured into ReadyCircuit™ assemblies to interconnect with a variety of ReadyCircuit™ process components.\u003c\/li\u003e\n\u003cli\u003eReadyCircuit™ bag assemblies are supplied as gamma-irradiated with a certificate of quality.\u003c\/li\u003e\n\u003cli\u003ePort orientation, bag designs, and supporting hardware ensures easily filling and product recovery.\u003c\/li\u003e\n\u003cli\u003eExceptional film clarity, low oxygen permeability, high tensile strength.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eReadyCircuit™ bag assembly types with ReadyKleer™ film\u003c\/p\u003e\n\n\u003cp\u003eScale-up capability is offered by ReadyCircuit™ bags, for maintained continuity in your development efforts. Bag types include sample bags for small-volume applications, 50 L horizontal pillow bag, 1, 5, 10, and 20 L 2-D hanging bags for use on mobile carts or trays, and 50, 100, 200, 500 and 1000 L 3-D bags for large-scale production.\u003c\/p\u003e\n\n\u003cp\u003eAseptic design\u003c\/p\u003e\n\n\u003cp\u003eReadyCircuit™ bags are supplied gamma irradiated with ReadyMate single-use connectors. Port configuration varies by bag type. Different sizes allow scale-up so continuity can be maintained.\u003c\/p\u003e\n\n\u003cp\u003eRelated accessories\u003c\/p\u003e\n\n\u003cp\u003eReadyKart mobile processing stations and supporting hardware are optimized to enable organization of ReadyCircuit™ assemblies into an efficient process scheme.\u003c\/p\u003e\n\n\u003cp\u003eReadyToProcess Bins are suitable for in-process storage and handling of bioprocess fluids, buffers, and media.\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-17235-pdf\"\u003eData file (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-16382-pdf\"\u003eInstructions for use (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Cytiva","offers":[{"title":"ReadyKart \/ 4 ports \/ 100 L","offer_id":45982099243087,"sku":"12410206","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"ReadyKart \/ 4 ports \/ 200 L","offer_id":45982099275855,"sku":"12410208","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"ReadyKart \/ 5 ports \/ 100 L","offer_id":45982099308623,"sku":"12410207","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"ReadyKart \/ 5 ports \/ 200 L","offer_id":45982099341391,"sku":"12410209","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/USE0lInv-UKI6fsFcB_YAg-original-png_a80e7c7b-92aa-4c07-a48f-7a5888492f83.png?v=1785958293"},{"product_id":"readytoprocess-single-use-hollow-fiber-cartridges-for-microfiltration-rtpcfp-2-e-4ms","title":"ReadyToProcess™ single-use hollow fiber cartridges for microfiltration","description":"\u003cp\u003eSingle-use hollow fiber microfiltration cartridges with ReadyMate single-use connectors enable easy installation and aseptic connections to ReadyCircuit products.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eLow total organic carbon, endotoxin, and conductivity.\u003c\/li\u003e\n\u003cli\u003ePreconditioned for reduced conductivity and TOC level.\u003c\/li\u003e\n\u003cli\u003eGamma irradiated for sterility.\u003c\/li\u003e\n\u003cli\u003eMinimal or no rinse-out needed prior to use.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eSafer, faster drug development\u003c\/p\u003e\u003cp\u003eReadyToProcess hollow fiber cartridges enable simpler, safer, and faster drug development by eliminating device preparation steps such as wetting and sterilizing. The single-use nature of the cartridges eliminates the need for cleaning protocols and cleaning validation.\u003c\/p\u003e\u003cp\u003eReadyMate single-use connectors\u003c\/p\u003e\u003cp\u003eReadyToProcess hollow fiber cartridges incorporate ReadyMate single-use connectors. These allow installation and aseptic connection of ReadyToProcess hollow fiber cartridges to other components within the ReadyToProcess product platform, including bioprocess containers and tubing assemblies.\u003c\/p\u003e\u003cp\u003eReadyToProcess hollow fiber cartridges are processed to wet the membrane, lower total organic carbon (TOC) and conductivity, and minimize endotoxin and bioburden levels. They are then packaged in high-purity water and sterilized via exposure to gamma radiation.\u003c\/p\u003e\u003cp\u003eTypical applications of ReadyToProcess hollow fiber cartridges include:\n\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eAseptic clarification and purification of vaccines, monoclonal antibodies, recombinant proteins, and plasmids.\u003c\/li\u003e\n\u003cli\u003eAseptic cell processing.\u003c\/li\u003e\n\u003cli\u003eEnvironments where terminal sterilization is not feasible.\u003c\/li\u003e\n\u003cli\u003ePreclinical through large-scale manufacturing.\u003c\/li\u003e\n\u003cli\u003eFast-track drug development processes.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-18402-pdf\"\u003eData file (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca 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use.\u003c\/li\u003e\n\u003cli\u003ePreconditioned for reduced conductivity and TOC level.\u003c\/li\u003e\n\u003cli\u003eGamma irradiated for sterility.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eCross flow filtration solutions for safer, faster drug development\u003c\/p\u003e\n\n\u003cp\u003eCross flow filtration (CFF), also known as tangential flow filtration (TFF), is a fast and efficient technique for concentration, diafiltration (buffer exchange and desalting), and fractionation of biomolecules. ReadyToProcess™ hollow fiber cartridge filters enable simpler, safer, and faster drug development by eliminating device preparation steps such as wetting and sterilizing. The single-use nature of the cartridges allows elimination of associated cleaning protocols and cleaning validation.\u003c\/p\u003e\n\n\u003cp\u003eReadyMate™ single-use connectors\u003c\/p\u003e\n\n\u003cp\u003eReadyToProcess™ hollow fiber cartridge filters incorporate ReadyMate™ disposable aseptic connectors. These allow installation and aseptic connection of ReadyToProcess™ hollow fiber cartridges to other components within the ReadyToProcess™ product platform, including bioprocess containers and tubing assemblies.\u003c\/p\u003e\n\n\u003cp\u003eOur hollow fiber cartridges are processed to wet the membrane, lower total organic carbon (TOC) and conductivity, and minimize endotoxin and bioburden levels.\u003c\/p\u003e\n\n\u003cp\u003eHow to identify and order the right ultrafiltration cartridge filter for your application\u003c\/p\u003e\n\n\u003cp\u003eCytiva cartridges are produced in a range of formats and housing sizes to suit different applications and process scales. 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These metal sleeves, strategically placed around the syringe, ensure optimal thermal contact between the syringe heaters of the system and syringes of varying sizes.\u003c\/p\u003e\n\u003cp\u003eHeating package inserts are specific to the instrument. See the order table for more information.\u003c\/p\u003e\n\n\u003cp\u003eNanoAssemblr™ Ignite heating package compatibility\u003c\/p\u003e\n\n\u003cp\u003eEach NanoAssemblr™ Ignite heating package insert is labeled with a size. The table below shows which insert is appropriate for each compatible syringe manufacturer.\u003c\/p\u003e\n\n\u003cdiv class=\"table-responsive\"\u003e\n\u003ctable class=\"table table-bordered\"\u003e\n\t\u003cthead\u003e\n\t\t\u003ctr\u003e\n\t\t\t\u003ctd rowspan=\"2\" style=\"text-align: center;\"\u003eSyringe size\u003c\/td\u003e\n\t\t\t\u003ctd colspan=\"8\" style=\"text-align: center;\"\u003eHeating insert size\u003c\/td\u003e\n\t\t\u003c\/tr\u003e\n\t\t\u003ctr\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003eBD\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003eB Braun Injekt\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003eB Braun Omnifix\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003eTerumo\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003eShinva Ande\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003eKDL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003eWEGO\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003eKOVAX\u003c\/td\u003e\n\t\t\u003c\/tr\u003e\n\t\u003c\/thead\u003e\n\t\u003ctbody\u003e\n\t\t\u003ctr\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e1 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e1 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e1 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e1 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e1 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e3 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e1 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003ex\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e3 mL\u003c\/td\u003e\n\t\t\u003c\/tr\u003e\n\t\t\u003ctr\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e2 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003ex\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003ex\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003ex\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003ex\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e3 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e3 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e3 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003ex\u003c\/td\u003e\n\t\t\u003c\/tr\u003e\n\t\t\u003ctr\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e2.5 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003ex\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003ex\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003ex\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003ex\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003ex\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003ex\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003ex\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003ex\u003c\/td\u003e\n\t\t\u003c\/tr\u003e\n\t\t\u003ctr\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e3 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e3 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003ex\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e3 mL-O\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e3 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e3 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003ex\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003ex\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003ex\u003c\/td\u003e\n\t\t\u003c\/tr\u003e\n\t\t\u003ctr\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e5 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e5 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e5 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e5 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e5 mL-T\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e5 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e5 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e5 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003ex\u003c\/td\u003e\n\t\t\u003c\/tr\u003e\n\t\t\u003ctr\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e10 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e10 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e10 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e10 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e10 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e10 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e10 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e10 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003ex\u003c\/td\u003e\n\t\t\u003c\/tr\u003e\n\t\t\u003ctr\u003e\n\t\t\t\u003ctd colspan=\"9\"\u003eX: Syringe not suppotred by Ignite instrument\u003c\/td\u003e\n\t\t\u003c\/tr\u003e\n\t\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\n\u003cp\u003eNanoAssemblr™ Ignite+ heating package compatibility\u003c\/p\u003e\n\n\u003cp\u003eEach NanoAssemblr™ Ignite+ heating package insert is labeled with a size. The table below shows which insert is appropriate for each compatible syringe manufacturer.\u003c\/p\u003e\n\n\u003cdiv class=\"table-responsive\"\u003e\n\u003ctable class=\"table table-bordered\"\u003e\n\t\u003cthead\u003e\n\t\t\u003ctr\u003e\n\t\t\t\u003ctd rowspan=\"2\" style=\"text-align: center;\"\u003eSyringe size\u003c\/td\u003e\n\t\t\t\u003ctd colspan=\"8\" style=\"text-align: center;\"\u003eHeating insert size\u003c\/td\u003e\n\t\t\u003c\/tr\u003e\n\t\t\u003ctr\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003eBD\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003eB Braun Injekt\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003eB Braun Omnifix\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003eTerumo\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003eShinva Ande\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003eKDL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003eWEGO\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003eKOVAX\u003c\/td\u003e\n\t\t\u003c\/tr\u003e\n\t\u003c\/thead\u003e\n\t\u003ctbody\u003e\n\t\t\u003ctr\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e1 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e1 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e1 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e1 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e1 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e3 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e1 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003ex\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e3 mL\u003c\/td\u003e\n\t\t\u003c\/tr\u003e\n\t\t\u003ctr\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e2 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003ex\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003ex\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003ex\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003ex\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e3 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e3 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e3 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003ex\u003c\/td\u003e\n\t\t\u003c\/tr\u003e\n\t\t\u003ctr\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e2.5 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003ex\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003ex\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003ex\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003ex\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003ex\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003ex\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003ex\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003ex\u003c\/td\u003e\n\t\t\u003c\/tr\u003e\n\t\t\u003ctr\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e3 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e3 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003ex\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e3 mL-O\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e3 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e3 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003ex\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003ex\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003ex\u003c\/td\u003e\n\t\t\u003c\/tr\u003e\n\t\t\u003ctr\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e5 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e5 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e5 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e5 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e5 mL-T\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e5 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e5 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e5 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003ex\u003c\/td\u003e\n\t\t\u003c\/tr\u003e\n\t\t\u003ctr\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e10 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e10 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e10 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e10 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e10 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e10 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e10 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e10 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003ex\u003c\/td\u003e\n\t\t\u003c\/tr\u003e\n\t\t\u003ctr\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e20 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e20 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e20 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e20 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e20 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003ex\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003ex\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003ex\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003ex\u003c\/td\u003e\n\t\t\u003c\/tr\u003e\n\t\t\u003ctr\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e30 mL\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e✓\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003ex\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e✓\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003e✓\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003ex\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003ex\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003ex\u003c\/td\u003e\n\t\t\t\u003ctd style=\"text-align: center;\"\u003ex\u003c\/td\u003e\n\t\t\u003c\/tr\u003e\n\t\t\u003ctr\u003e\n\t\t\t\u003ctd colspan=\"9\"\u003eX: Syringe not suppotred by Ignite+ instrument\u003cbr\u003e\n\t\t\t✓: No insert is needed for the specified surringe\u003c\/td\u003e\n\t\t\u003c\/tr\u003e\n\t\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e","brand":"Cytiva","offers":[{"title":"Ignite \/ 1","offer_id":45982107697231,"sku":"NIN0068","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Ignite+ \/ 1 (1001404)","offer_id":45982107729999,"sku":"1001404","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Ignite+ \/ 1 (1001403)","offer_id":45982107762767,"sku":"1001403","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/Q3_qn2V0Taq6_E6fRYfc1Q-original-png_0b3434df-5ac5-4736-92f8-f3de1552e289.png?v=1785958370"},{"product_id":"genvoy-ilm-reagents-and-kits-1002763","title":"GenVoy-ILM™ reagents and kits","description":"\u003cp\u003eGenVoy-ILM™ reagents are LNP reagents that enable the production of RNA-LNPs using the NanoAssemblr™ Ignite™ and Ignite+™ instruments. The resulting LNPs formed by mixing GenVoy-ILM™ and nucleic acids using Ignite™ and Ignite+™ instruments feature a homogeneous core structure. This reagent has been designed to:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eEnable target validation: The excellent transfection efficiency and remarkably low cytotoxicity exhibited by GenVoy-ILM™ LNPs enable effective RNA-mediated gene silencing, gene expression, and gene editing in primary cells, stem cells, and non-adherent cells.\u003c\/li\u003e\n\u003cli\u003eDemonstrate therapeutic performance: These reagents are designed to enable effective formulation in developing proof of concept data for RNA-based therapeutics.\u003c\/li\u003e\n\u003cli\u003eEnable process development: The resulting formulation can be used as a reference formulation at all development scales to establish a scalable process for GMP manufacturing to support clinical development\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThis reagent is available in two formats, smaller and larger volumes for different formulation needs, with or without added dye for visualization.\u003c\/p\u003e\n\n\u003cp class=\"-font--plus-1 -padding--title-md\"\u003eGenVoy-ILM™ demo on the NanoAssemblr™ Ignite™ system\u003c\/p\u003e\n\n\u003cp\u003e\u003ciframe allowfullscreen=\"\" allowtransparency=\"true\" class=\"vidyard_iframe\" frameborder=\"0\" height=\"360\" referrerpolicy=\"no-referrer-when-downgrade\" scrolling=\"no\" src=\"\/\/play.vidyard.com\/ZcqTxsshgwJjYf1xdRxfp9.html?\" title=\"GenVoy Ignite Video Demo\" width=\"640\"\u003e\u003c\/iframe\u003e\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\u003cli\u003e\u003ca href=\"https:\/\/d3.cytivalifesciences.com\/prod\/IFU\/0NIN1182.pdf\"\u003eInstructions for use (PDF)\u003c\/a\u003e\u003c\/li\u003e\u003c\/ul\u003e","brand":"Cytiva","offers":[{"title":"Ignite, Ignite+ (1002763)","offer_id":45982111498319,"sku":"1002763","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Ignite, Ignite+ (1002771)","offer_id":45982111531087,"sku":"1002771","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Ignite, Ignite+ (1002773)","offer_id":45982111563855,"sku":"1002773","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Ignite, Ignite+ (1002769)","offer_id":45982111596623,"sku":"1002769","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Ignite, Ignite+ (1002775)","offer_id":45982111629391,"sku":"1002775","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/sDyieNvbSLiZkTUUKY4mkg-original-png_98021580-9989-4df5-b0d7-9cc91e7250eb.png?v=1785958429"},{"product_id":"nanoassemblr-spark-cartridges-nis0013","title":"NanoAssemblr™ Spark™ cartridges","description":"\u003cp\u003eNanoAssemblr™ Spark™ cartridges are equipped with NxGen™ mixing technology for use on the NanoAssemblr™ Spark™ systems for nanoparticle formulation.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eNon-turbulent flow conditions for particle formation ensure reproducible results for a wide range of nanoparticle types\u003c\/li\u003e\n\u003cli\u003eNo priming or cleaning required; cartridges are single-use and gamma-irradiated for sterility\u003c\/li\u003e\n\u003cli\u003eCompatible with a wide range of solvents to make a diverse array of nanomedicine formulations\u003c\/li\u003e\n\u003cli\u003eRapid, controlled, homogenous mixing results in reproducible, high-quality nanoparticles\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Cytiva","offers":[{"title":"NanoAssemblr Spark Cartridges - 80 Pack","offer_id":45982112022607,"sku":"NIS0013","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"NanoAssemblr Spark Cartridges - 20 Pack","offer_id":45982112055375,"sku":"NIS0009","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/CR-m_hKvRfWYf1zpNQg97w-original-png_5a1dca27-6394-449c-b94f-3261e2babc45.png?v=1785958437"},{"product_id":"xuri-il-2-growth-factor-29062790","title":"Xuri™ IL-2 growth factor","description":"\u003cp\u003eInterleukin-2 available in two formats – powder or liquid. This growth factor reliably activates T lymphocytes for efficient cell expansion. Meets USP \u0026lt;1043\u0026gt; for cell therapy ancillary material as applicable to supplier.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eGain peace of mind. Produced under a certified GMP license regularly qualified by licensing authorities. Sterility- and endotoxin-tested according to USP.\u003c\/li\u003e\n\u003cli\u003eReproducible. No need to revalidate each new lot.\u003c\/li\u003e\n\u003cli\u003eManage contamination risk. Easily connect Xuri IL-2 Syringe to a bag via Luer connection.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eFunctionality of this product is based on biological activity assays. Animal component-free. All Xuri reagents and media are compatible with Xuri Cell Expansion System.\u003c\/p\u003e\u003cp\u003eInterleukin-2\u003c\/p\u003e\u003cp\u003eInterleukin-2 promotes the growth, activity and maintenance of T and B lymphocytes. 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USP Chapter ‹1043› ‘Ancillary materials for cell, gene and tissue-engineered products’ has been followed in the design of these products.\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-17164-pdf\"\u003eData file (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/d3.cytivalifesciences.com\/prod\/IFU\/29083091.pdf\"\u003eInstructions for use (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Cytiva","offers":[{"title":"Standard \/ Standard","offer_id":45982111891535,"sku":"29062789","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Liquid \/ 1 mg","offer_id":45982111924303,"sku":"29295127","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Powder \/ 1 mg","offer_id":45982111957071,"sku":"29062790","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/digi-27179-original-png_4232634e-62f6-44c0-8487-5541c9baae71.png?v=1785958436"},{"product_id":"xdr-50-pro-bag-888-0086-c","title":"XDR-50 Pro bag","description":null,"brand":"Cytiva","offers":[{"title":"Default Title","offer_id":45982112120911,"sku":"888-0086-C","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/69c2a45ee6724ce6b5869640310fc044_c0068a0c-cd59-4882-b332-109d471ad662.png?v=1785956229"},{"product_id":"process-scale-ultrafiltration-hollow-fiber-tangential-flow-cartridges-ufp-750-c-55a","title":"Process scale ultrafiltration hollow fiber tangential flow cartridges","description":"\u003cp\u003eHollow fiber cartridges for process scale ultrafiltration, with a polysulfone membrane available in a range of pore sizes.\u003c\/p\u003e\n\u003cp\u003eWide selection, standard connection\u003c\/p\u003e\u003cp\u003eProcess-scale hollow fiber cartridges offered by Cytiva are provided in 8 basic configurations covering a membrane area range of 0.92 to 28 m² (9.9 to 300 ft²) depending on the fiber internal diameter.\u003c\/p\u003e\u003cp\u003eAll of these process-scale cartridges feature sanitary connections for both the feed\/retentate and permeate ports. 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This provides the flexibility to add supplements to the bag within a functionally closed system.\u003c\/p\u003e\u003cp\u003eMinimize variability for consistent performance\u003c\/p\u003e\u003cp\u003eXuri T cell expansion medium is manufactured under a strict quality management system and the fully validated production process ensures consistency across batches, improving control in achieving the desired cell numbers.\u003c\/p\u003e\u003cp\u003eUSP \u0026lt;1043\u0026gt; compliance\u003c\/p\u003e\u003cp\u003eA smooth submission process is key when dealing with cell therapy regulatory requirements. To help users assess and document production processes, Cytiva supplies Xuri T cell expansion medium with a comprehensive documentation support package that meets USP \u0026lt;1043\u0026gt; ‘ancillary materials for cell, gene, and tissue-engineered products’, within the responsibilities applicable to a supplier.\u003c\/p\u003e\u003cp\u003eEnd user responsibility\u003c\/p\u003e\u003cp\u003eOther aspects of USP \u0026lt;1043\u0026gt; will be the responsibility of the end user to assess. Cytiva cannot fulfill USP \u0026lt;1043\u0026gt; in regard to application and therapy specific aspects (e.g., use in finished therapeutic, assessment of removal from a finished therapeutic and possibly biocompatibility, cytotoxicity or adventitious agent testing). The product is chemically defined and free from any human or animal derived components.\u003c\/p\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/digi-18382-pdf\"\u003eData file (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/d3.cytivalifesciences.com\/prod\/IFU\/29112375.pdf\"\u003eInstructions for use (PDF)\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Cytiva","offers":[{"title":"1000 mL","offer_id":45982115299407,"sku":"29185231","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Standard","offer_id":45982115332175,"sku":"29185230","price":0.0,"currency_code":"ILS","in_stock":true}]},{"product_id":"genvoy-ilm-t-cell-kits-for-mrna-1000701","title":"GenVoy-ILM™ T cell kits for mRNA","description":"\u003cp\u003eGenVoy-ILM™ T cell Kit for mRNA is a lipid nanoparticle (LNP) reagent mix optimized for the delivery of mRNA or CRISPR Cas9 mRNA with gRNA into human primary T cells using LNPs prepared on the NanoAssemblr™ Spark™ and Ignite™ systems.\u003c\/p\u003e\n\u003cp class=\"-font--plus-1 -padding--title-md\"\u003eGenVoy-ILM™ T cell Kits for mRNA offers the following benefits:\u003c\/p\u003e\n\n\u003cul\u003e\n\t\u003cli class=\"-font--body\"\u003e\n\u003cstrong\u003eHighly efficient knockout and expression:\u003c\/strong\u003e The mRNA or mRNA\/sgRNA can be delivered into activated human primary T cells consistently with high gene knockout efficiency.\u003c\/li\u003e\n\t\u003cli class=\"-font--body\"\u003e\n\u003cstrong\u003eHigh cell viability:\u003c\/strong\u003e Maintain high T cell viability, even after sequential genetic manipulation.\u003c\/li\u003e\n\t\u003cli class=\"-font--body\"\u003e\n\u003cstrong\u003eScalable:\u003c\/strong\u003e Scale your cell therapy research on the NanoAssemblr™ platform from discovery to preclinical.\u003c\/li\u003e\n\t\u003cli class=\"-font--body\"\u003e\n\u003cstrong\u003eValidated with T cell manufacturing workflow:\u003c\/strong\u003e Optimized and validated for downstream T cell culture workflow.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eThe kits enable researchers to establish a clinically relevant and scalable method for \u003cem\u003eex vivo\u003c\/em\u003e gene delivery and gene editing to advance the development of T cell therapies. These kits can be used at various stages of cell therapy research and development from discovery to preclinical across the NanoAssemblr™ platforms.\u003c\/p\u003e\n\n\u003cp class=\"-font--plus-1 -padding--title-md\"\u003eGreater ratio of engineered T cells compared to electroporation (EP)\u003c\/p\u003e\n\n\u003cp class=\"-font--minus-1\"\u003eUsing the GenVoy-ILM™ T cell Kit for mRNA to deliver mRNA into activated human primary T cells results in an increased number of engineered T cells. This method demonstrates a more effective gene delivery method compared to EP.\u003c\/p\u003e\n\n\u003cp\u003e\u003cimg alt=\"\" class=\"img-responsive center-block\" src=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/jZUKP9BQSEulL99fjFiXWA-large\" style=\"max-width: 1250px;\"\u003e\u003c\/p\u003e\n\n\u003cp class=\"-font--minus-1\"\u003eTransfection efficiency was measured by protein expression via flow cytometry at 24 and 48 hours post-treatment. EP was performed by following the manufacturer’s protocol, and LNP treatment was performed following the GenVoy-ILM™ T cell Kit for mRNA on Spark™ protocol. Untreated cells (UT) were used as control. **p\u0026lt;0.01, ****p\u0026lt;0.0001 by one-way ANOVA.\u003c\/p\u003e\n\n\u003cp class=\"-font--plus-1 -padding--title-md\"\u003eUniform cellular protein expression\u003c\/p\u003e\n\n\u003cp\u003eEngineering human primary T cells using the GenVoy-ILM™ T cell Kit for mRNA results in highly uniform protein expression across the treated cell population.\u003c\/p\u003e\n\n\u003cp\u003e\u003cimg alt=\"\" class=\"img-responsive center-block\" src=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/1CPxSKqlTTSsuN91NrkbTg-original-png\" style=\"max-width: 1250px;\"\u003e\u003c\/p\u003e\n\n\u003cp class=\"-font--minus-1\"\u003eRepresentative mean fluorescence intensity (MFI) plots of cell surface protein expression were generated using flow cytometry at 24 and 48 hours post-treatment. EP was performed by following the manufacturer’s protocol. Untreated cells (UT) were used as controls.\u003c\/p\u003e\n\n\u003cp class=\"-font--plus-1 -padding--title-md\"\u003eHighly viable T cells\u003c\/p\u003e\n\n\u003cp\u003eActivated human primary T cells remain highly viable after \u003cem\u003eex vivo\u003c\/em\u003e gene delivery using the GenVoy-ILM™ T cell Kit for mRNA.\u003c\/p\u003e\n\n\u003cp\u003e\u003cimg alt=\"\" class=\"img-responsive center-block\" src=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/mCKHQJyVQlWPxdADf2_KoQ-original-png?v=343d1041\" style=\"max-width: 1250px;\"\u003e\u003c\/p\u003e\n\n\u003cp class=\"-font--minus-1\"\u003eCell viability was measured via flow cytometry at 24 and 48 hours post-treatment. EP was performed by following the manufacturer’s protocol, and LNP treatment was performed following the GenVoy-ILM™ T cell Kit for mRNA on Spark™ protocol. Untreated cells (UT) were used as controls. ****p\u0026lt;0.0001 by one-way ANOVA.\u003c\/p\u003e\n\n\u003cp class=\"-font--plus-1 -padding--title-md\"\u003eMulti-step engineering of T cells for off-the-shelf cell therapy\u003c\/p\u003e\n\n\u003cp\u003eAchieve highly efficient genome editing knockouts in combination with high levels of CD19 CAR expression. This allows for the engineering of functional and viable “universal” CAR T cells that effectively kill CD19+ tumor cells.\u003c\/p\u003e\n\n\u003cp\u003e\u003cimg alt=\"\" class=\"img-responsive center-block\" src=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/V48HbQ3hQkqHupJqZpOZEA-original-png?v=60dbe059\" style=\"max-width: 1150px;\"\u003e\u003c\/p\u003e\n\n\u003cp class=\"-font--minus-1\"\u003eA) Schematic illustration of experiment. mRNA-LNPs containing sgRNA + Cas9 mRNA were added to primary T cells. Cells expanded prior to treatment with CD19 CAR mRNA-LNPs. At 24 hours post CAR mRNA-LNP treatment, CD19+ T cell killing assay was conducted for 16 hours. B) TCR knockout efficiency was assessed. Starting sample was TCR negative selected to further purify the TCR- population. C) Left: Percent CD19 CAR expression 24 hours after treatment with CAR mRNA-LNPs at 3.2 μg RNA\/million cells, when population is TCR+, or TCR−. Right: Corresponding cell viabilities, normalized to the untreated population. D) Functional killing of CD19+ B cells (SUP-B15) by either UT, TCR+\/CAR+, or gene-edited TCR−\/CAR+ T cells at the indicated effector to target ratios (E:T). For all, a dose of 3.2 μg RNA\/million cells was applied. Error bars represent standard deviation. Statistical significance was evaluated using t-tests or one-way ANOVA among the shown groups (2).\u003c\/p\u003e\n\n\u003cp class=\"-font--plus-1 -padding--title-md\"\u003eScale up from discovery to preclinical\u003c\/p\u003e\n\n\u003cp\u003eThe data demonstrates that the GenVoy-ILM™ T cell Kits and the scalable NanoAssemblr™ platform enable robust and equivalent performance on both the Spark™ and Ignite™ instruments enabling scale up from discovery to preclinical.\u003c\/p\u003e\n\n\u003cp\u003e\u003cimg alt=\"\" class=\"img-responsive center-block\" src=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/_6AxVcEQSKKQptBRUsXjCw-original-png?v=fe1a20aa\" style=\"max-width: 1250px;\"\u003e \u003cimg alt=\"\" class=\"img-responsive center-block\" src=\"https:\/\/cdn.cytivalifesciences.com\/api\/public\/content\/812C6PHyQ7eq6Rr6GInWrw-original-png?v=04b8a698\" style=\"max-width: px;\"\u003e\u003c\/p\u003e\n\n\u003cp class=\"-font--minus-1\"\u003eA) GFP and B) CD19 CAR transfection efficiency 24 hours post mRNA-LNP addition. C) Levels of single target (T cell receptor, TCR) knockout, and D) Double target (TCR and CD52) knockout through sgRNA and Cas9 mRNA delivery. E) Functional killing of CD19+ B cells (SUP-B15) in a 16-hour co-culture experiment. For all: a dose of 3.2 μg RNA\/million cells was applied to human primary T cells. RNA-LNPs were prepared according to the GenVoy-ILM™ T cell Kit for mRNA on Spark™ or Ignite™ user guides. Average gene expression and gene knockout was detected by flow cytometry showing at minimum n=8 independent RNA-LNP preparations and n=2 donors. Functional killing performance was detected by flow cytometry showing n=2 independent RNA-LNP preparations and n=2 donors. Error bars represent standard deviation with statistical significance evaluated using t-tests among selected groups (2).\u003c\/p\u003e\n\n\u003cp class=\"-font--plus-1 -padding--title-md\"\u003eKit components\u003c\/p\u003e\n\n\u003cdiv class=\"table-responsive\"\u003e\n\u003ctable class=\"table table-bordered\"\u003e\n\t\u003cthead\u003e\n\t\t\u003ctr\u003e\n\t\t\t\u003cth class=\"-font--body\"\u003e \u003c\/th\u003e\n\t\t\t\u003cth class=\"-font--body\"\u003eGenVoy-ILM™ T cell Kit for mRNA, Spark™, (Part no. 1000700)\u003c\/th\u003e\n\t\t\t\u003cth class=\"-font--body\"\u003eGenVoy-ILM™ T cell Kit for mRNA w\/ 5 Spark™ cartridge, (Part no. 1000683)\u003c\/th\u003e\n\t\t\t\u003cth class=\"-font--body\"\u003eGenVoy-ILM™ T cell Kit for mRNA, Ignite™, 3 mL, (Part no. 1001144)\u003c\/th\u003e\n\t\t\t\u003cth class=\"-font--body\"\u003eGenVoy-ILM™ T cell Kit for mRNA, Ignite™, 6 mL, (Part no. 1001161)\u003c\/th\u003e\n\t\t\u003c\/tr\u003e\n\t\u003c\/thead\u003e\n\t\u003ctbody\u003e\n\t\t\u003ctr\u003e\n\t\t\t\u003ctd class=\"-font--body\"\u003eLipid mix\u003c\/td\u003e\n\t\t\t\u003ctd class=\"-font--body\"\u003e90 µL\u003c\/td\u003e\n\t\t\t\u003ctd class=\"-font--body\"\u003e90 µL\u003c\/td\u003e\n\t\t\t\u003ctd class=\"-font--body\"\u003e3 mL\u003c\/td\u003e\n\t\t\t\u003ctd class=\"-font--body\"\u003e6 mL\u003c\/td\u003e\n\t\t\u003c\/tr\u003e\n\t\t\u003ctr\u003e\n\t\t\t\u003ctd class=\"-font--body\"\u003eFormulation buffer (10X)\u003c\/td\u003e\n\t\t\t\u003ctd class=\"-font--body\"\u003e30 µL\u003c\/td\u003e\n\t\t\t\u003ctd class=\"-font--body\"\u003e30 µL\u003c\/td\u003e\n\t\t\t\u003ctd class=\"-font--body\"\u003e2 mL\u003c\/td\u003e\n\t\t\t\u003ctd class=\"-font--body\"\u003e4 mL\u003c\/td\u003e\n\t\t\u003c\/tr\u003e\n\t\t\u003ctr\u003e\n\t\t\t\u003ctd class=\"-font--body\"\u003eDilution buffer (10X)\u003c\/td\u003e\n\t\t\t\u003ctd class=\"-font--body\"\u003e900 µL\u003c\/td\u003e\n\t\t\t\u003ctd class=\"-font--body\"\u003e900 µL\u003c\/td\u003e\n\t\t\t\u003ctd class=\"-font--body\"\u003e40 mL\u003c\/td\u003e\n\t\t\t\u003ctd class=\"-font--body\"\u003e80 mL\u003c\/td\u003e\n\t\t\u003c\/tr\u003e\n\t\t\u003ctr\u003e\n\t\t\t\u003ctd class=\"-font--body\"\u003eCryopreservation buffer (2X)\u003c\/td\u003e\n\t\t\t\u003ctd class=\"-font--body\"\u003e-\u003c\/td\u003e\n\t\t\t\u003ctd class=\"-font--body\"\u003e-\u003c\/td\u003e\n\t\t\t\u003ctd class=\"-font--body\"\u003e3 mL\u003c\/td\u003e\n\t\t\t\u003ctd class=\"-font--body\"\u003e6 mL\u003c\/td\u003e\n\t\t\u003c\/tr\u003e\n\t\t\u003ctr\u003e\n\t\t\t\u003ctd class=\"-font--body\"\u003eApolipoprotein-E (ApoE)\u003c\/td\u003e\n\t\t\t\u003ctd class=\"-font--body\"\u003e50 µg\u003c\/td\u003e\n\t\t\t\u003ctd class=\"-font--body\"\u003e50 µg\u003c\/td\u003e\n\t\t\t\u003ctd class=\"-font--body\"\u003e500 µg\u003c\/td\u003e\n\t\t\t\u003ctd class=\"-font--body\"\u003e500 µg x 2\u003c\/td\u003e\n\t\t\u003c\/tr\u003e\n\t\t\u003ctr\u003e\n\t\t\t\u003ctd class=\"-font--body\"\u003eSpark Cartridges\u003c\/td\u003e\n\t\t\t\u003ctd class=\"-font--body\"\u003e-\u003c\/td\u003e\n\t\t\t\u003ctd class=\"-font--body\"\u003e5\u003c\/td\u003e\n\t\t\t\u003ctd class=\"-font--body\"\u003e-\u003c\/td\u003e\n\t\t\t\u003ctd class=\"-font--body\"\u003e-\u003c\/td\u003e\n\t\t\u003c\/tr\u003e\n\t\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003ch2\u003eDocuments\u003c\/h2\u003e\n\u003cul\u003e\u003cli\u003e\u003ca href=\"https:\/\/d3.cytivalifesciences.com\/prod\/IFU\/01001343.pdf\"\u003eInstructions for use (PDF)\u003c\/a\u003e\u003c\/li\u003e\u003c\/ul\u003e","brand":"Cytiva","offers":[{"title":"Ignite (1001144)","offer_id":45982115627087,"sku":"1001144","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Ignite (1001161)","offer_id":45982115659855,"sku":"1001161","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Spark (1000701)","offer_id":45982115692623,"sku":"1000701","price":0.0,"currency_code":"ILS","in_stock":true},{"title":"Spark (29874064)","offer_id":45982115725391,"sku":"29874064","price":0.0,"currency_code":"ILS","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/files\/W-GiOF0YT7G2-ss2TM1BvQ-original-png_b3850b8e-04d7-4599-9cd8-cfb896f2b679.png?v=1785958486"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0712\/0748\/5519\/collections\/digi-49605-original-png_f49ea7b5-4e1e-4ad4-be3d-800ec3ca0146.png?v=1790861248","url":"https:\/\/www.danyel.co.il\/collections\/bioprocessing-and-cell-therapy.oembed","provider":"danyel biotech","version":"1.0","type":"link"}